5F74A

Crystal structure of chrebp:14-3-3 complex bound with amp
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
231
structure length
229
Chain Sequence
TMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLILNATQAESKVFYLKMKGDYFRYLSEVASGENKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Metabolite Regulation of Nuclear Localization of Carbohydrate-response Element-binding Protein (ChREBP): ROLE OF AMP AS AN ALLOSTERIC INHIBITOR.
pubmed doi rcsb
molecule tags Transcription
source organism Mus musculus
molecule keywords 14-3-3 protein beta/alpha
total genus 98
structure length 229
sequence length 231
ec nomenclature
pdb deposition date 2015-12-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 5f74A00
3SPRA 5LX2A 4J6SA 3EFZA 3U9XA 4HKCA 4N7YA 3UBWA 2C23A 4DHUA 4O46A 1A38A 4DATA 5D2DA 5BTVA 3SMLA 1YWTA 1A37A 5LHOA 4DX0A 3T0LA 4N84A 3RDHA 2BTPA 2NPMA 3SMOA 1O9FA 3SMMA 3IQUA 3E6YA 4IHLA 4DNKA 3P1QA 3P1SA 5LVZA 3NKXA 2C74A 4DHNA 4WRQA 4DHTA 5EWZA 4JDDA 1O9DA 3P1NA 1QJAA 4FL5A 1YZ5A 3SMNA 4N7GA 4ZDRA 1O9EA 4DHRA 2BR9A 1QJBA 4FJ3A 5D3FA 4Y32A 4GNTA 2C1NA 2O8PA 4Y5IA 3SP5A 3CU8A 5BY9A 2C1JA 2B05A 3IQJA 3SMKA 5LU2A 5LU1A 3UALA 5EXAA 1O9CA 3MHRA 3O8IA 5F74A 4DHMA 4DHQA 2V7DA 4F7RA 2O98A 3AXYC 3M51A 2WH0A 5J31A 2C63A 3T0MA 5D3EA 4E2EA 3P1PA 3P1RA 4DHSA 1A4OA 4IEAA 2BQ0A 2O02A 4QLIA 4FR3A 3UX0A 3UZDA 4DHOA 4ZQ0A 3LW1A 4DAUA 4JC3A 1IB1A 5IQPA 3M50A 4BG6A 4DHPA 4Y3BA 3IQVA 3P1OA 5HF3A
chains in the Genus database with same CATH superfamily
3SPRA 5LX2A 4J6SA 3EFZA 3U9XA 4HKCA 4N7YA 3UBWA 2C23A 4DHUA 4O46A 3EB7A 1A38A 4DATA 5D2DA 5BTVA 3SMLA 4D8MA 1YWTA 1A37A 5LHOA 4DX0A 3T0LA 4N84A 3RDHA 2BTPA 2NPMA 3SMOA 4ARYA 1O9FA 4W8JA 3X0UA 3SMMA 4QX0A 3IQUA 3E6YA 4IHLA 4DNKA 3P1QA 3P1SA 5LVZA 3NKXA 4QX3A 1CIYA 4MOAA 2C74A 4DHNA 4WRQA 4DHTA 5EWZA 4JDDA 1O9DA 3P1NA 1QJAA 4FL5A 1YZ5A 4QX2A 1W99A 3SMNA 4N7GA 1URJA 4ZDRA 3CQGA 1O9EA 4DHRA 2BR9A 1QJBA 3CQCA 4FJ3A 1S2XA 5D3FA 4Y32A 4GNTA 2C1NA 2O8PA 4Y5IA 3SP5A 3CU8A 5BY9A 2C1JA 2B05A 3ZHEB 3IQJA 3SMKA 5LU2A 5LU1A 3UALA 5EXAA 1O9CA 3MHRA 3O8IA 5F74A 4DHMA 4DHQA 2V7DA 4F7RA 2O98A 3AXYC 3M51A 2WH0A 1DLCA 5J31A 2C63A 3T0MA 5D3EA 4E2EA 3P1PA 3P1RA 4DHSA 1A4OA 1I5PA 4IEAA 2BQ0A 2O02A 4QLIA 4FR3A 3UX0A 4QX1A 3UZDA 4DHOA 4ZQ0A 3LW1A 2C9KA 4ARXA 4DAUA 4JC3A 1IB1A 5IQPA 3M50A 4BG6A 4DHPA 3I4RA 4Y3BA 3IQVA 3P1OA 1JI6A 5HF3A
chains in the Genus database with same CATH topology
3SPRA 5LX2A 4J6SA 3EFZA 3U9XA 4HKCA 4N7YA 3UBWA 2C23A 4DHUA 4O46A 1A38A 4DATA 5D2DA 5BTVA 3SMLA 1YWTA 1A37A 5LHOA 4DX0A 3T0LA 4N84A 3RDHA 2BTPA 2NPMA 3SMOA 1O9FA 3SMMA 3IQUA 3E6YA 4IHLA 4DNKA 3P1QA 3P1SA 5LVZA 3NKXA 2C74A 4DHNA 4WRQA 4DHTA 5EWZA 4JDDA 1O9DA 3P1NA 1QJAA 4FL5A 1YZ5A 3SMNA 4N7GA 4ZDRA 1O9EA 4DHRA 2BR9A 1QJBA 4FJ3A 5D3FA 4Y32A 4GNTA 2C1NA 2O8PA 4Y5IA 3SP5A 3CU8A 5BY9A 2C1JA 2B05A 3IQJA 3SMKA 5LU2A 5LU1A 3UALA 5EXAA 1O9CA 3MHRA 3O8IA 5F74A 4DHMA 4DHQA 2V7DA 4F7RA 2O98A 3AXYC 3M51A 2WH0A 5J31A 2C63A 3T0MA 5D3EA 4E2EA 3P1PA 3P1RA 4DHSA 1A4OA 4IEAA 2BQ0A 2O02A 4QLIA 4FR3A 3UX0A 3UZDA 4DHOA 4ZQ0A 3LW1A 4DAUA 4JC3A 1IB1A 5IQPA 3M50A 4BG6A 4DHPA 4Y3BA 3IQVA 3P1OA 5HF3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SPR A;  5LX2 A;  4J6S A;  3EFZ A;  3U9X A;  4HKC A;  4N7Y A;  3UBW A;  2C23 A;  4DHU A;  4O46 A;  1A38 A;  4DAT A;  5D2D A;  5BTV A;  3SML A;  1YWT A;  1A37 A;  5LHO A;  4DX0 A;  3T0L A;  4N84 A;  3RDH A;  2BTP A;  2NPM A;  3SMO A;  1O9F A;  3SMM A;  3IQU A;  3E6Y A;  4IHL A;  4DNK A;  3P1Q A;  3P1S A;  5LVZ A;  3NKX A;  2C74 A;  4DHN A;  4WRQ A;  4DHT A;  5EWZ A;  4JDD A;  1O9D A;  3P1N A;  1QJA A;  4FL5 A;  1YZ5 A;  3SMN A;  4N7G A;  4ZDR A;  1O9E A;  4DHR A;  2BR9 A;  1QJB A;  4FJ3 A;  5D3F A;  4Y32 A;  4GNT A;  2C1N A;  2O8P A;  4Y5I A;  3SP5 A;  3CU8 A;  5BY9 A;  2C1J A;  2B05 A;  3IQJ A;  3SMK A;  5LU2 A;  5LU1 A;  3UAL A;  5EXA A;  1O9C A;  3MHR A;  3O8I A;  5F74 A;  4DHM A;  4DHQ A;  2V7D A;  4F7R A;  2O98 A;  3AXY C;  3M51 A;  2WH0 A;  5J31 A;  2C63 A;  3T0M A;  5D3E A;  4E2E A;  3P1P A;  3P1R A;  4DHS A;  1A4O A;  4IEA A;  2BQ0 A;  2O02 A;  4QLI A;  4FR3 A;  3UX0 A;  3UZD A;  4DHO A;  4ZQ0 A;  3LW1 A;  4DAU A;  4JC3 A;  1IB1 A;  5IQP A;  3M50 A;  4BG6 A;  4DHP A;  4Y3B A;  3IQV A;  3P1O A;  5HF3 A; 
#chains in the Genus database with same CATH topology
 3SPR A;  5LX2 A;  4J6S A;  3EFZ A;  3U9X A;  4HKC A;  4N7Y A;  3UBW A;  2C23 A;  4DHU A;  4O46 A;  3EB7 A;  1A38 A;  4DAT A;  5D2D A;  5BTV A;  3SML A;  4D8M A;  1YWT A;  1A37 A;  5LHO A;  4DX0 A;  3T0L A;  4N84 A;  3RDH A;  2BTP A;  2NPM A;  3SMO A;  4ARY A;  1O9F A;  4W8J A;  3X0U A;  3SMM A;  4QX0 A;  3IQU A;  3E6Y A;  4IHL A;  4DNK A;  3P1Q A;  3P1S A;  5LVZ A;  3NKX A;  4QX3 A;  1CIY A;  4MOA A;  2C74 A;  4DHN A;  4WRQ A;  4DHT A;  5EWZ A;  4JDD A;  1O9D A;  3P1N A;  1QJA A;  4FL5 A;  1YZ5 A;  4QX2 A;  1W99 A;  3SMN A;  4N7G A;  1URJ A;  4ZDR A;  3CQG A;  1O9E A;  4DHR A;  2BR9 A;  1QJB A;  3CQC A;  4FJ3 A;  1S2X A;  5D3F A;  4Y32 A;  4GNT A;  2C1N A;  2O8P A;  4Y5I A;  3SP5 A;  3CU8 A;  5BY9 A;  2C1J A;  2B05 A;  3ZHE B;  3IQJ A;  3SMK A;  5LU2 A;  5LU1 A;  3UAL A;  5EXA A;  1O9C A;  3MHR A;  3O8I A;  5F74 A;  4DHM A;  4DHQ A;  2V7D A;  4F7R A;  2O98 A;  3AXY C;  3M51 A;  2WH0 A;  1DLC A;  5J31 A;  2C63 A;  3T0M A;  5D3E A;  4E2E A;  3P1P A;  3P1R A;  4DHS A;  1A4O A;  1I5P A;  4IEA A;  2BQ0 A;  2O02 A;  4QLI A;  4FR3 A;  3UX0 A;  4QX1 A;  3UZD A;  4DHO A;  4ZQ0 A;  3LW1 A;  2C9K A;  4ARX A;  4DAU A;  4JC3 A;  1IB1 A;  5IQP A;  3M50 A;  4BG6 A;  4DHP A;  3I4R A;  4Y3B A;  3IQV A;  3P1O A;  1JI6 A;  5HF3 A; 
#chains in the Genus database with same CATH homology
 3SPR A;  5LX2 A;  4J6S A;  3EFZ A;  3U9X A;  4HKC A;  4N7Y A;  3UBW A;  2C23 A;  4DHU A;  4O46 A;  1A38 A;  4DAT A;  5D2D A;  5BTV A;  3SML A;  1YWT A;  1A37 A;  5LHO A;  4DX0 A;  3T0L A;  4N84 A;  3RDH A;  2BTP A;  2NPM A;  3SMO A;  1O9F A;  3SMM A;  3IQU A;  3E6Y A;  4IHL A;  4DNK A;  3P1Q A;  3P1S A;  5LVZ A;  3NKX A;  2C74 A;  4DHN A;  4WRQ A;  4DHT A;  5EWZ A;  4JDD A;  1O9D A;  3P1N A;  1QJA A;  4FL5 A;  1YZ5 A;  3SMN A;  4N7G A;  4ZDR A;  1O9E A;  4DHR A;  2BR9 A;  1QJB A;  4FJ3 A;  5D3F A;  4Y32 A;  4GNT A;  2C1N A;  2O8P A;  4Y5I A;  3SP5 A;  3CU8 A;  5BY9 A;  2C1J A;  2B05 A;  3IQJ A;  3SMK A;  5LU2 A;  5LU1 A;  3UAL A;  5EXA A;  1O9C A;  3MHR A;  3O8I A;  5F74 A;  4DHM A;  4DHQ A;  2V7D A;  4F7R A;  2O98 A;  3AXY C;  3M51 A;  2WH0 A;  5J31 A;  2C63 A;  3T0M A;  5D3E A;  4E2E A;  3P1P A;  3P1R A;  4DHS A;  1A4O A;  4IEA A;  2BQ0 A;  2O02 A;  4QLI A;  4FR3 A;  3UX0 A;  3UZD A;  4DHO A;  4ZQ0 A;  3LW1 A;  4DAU A;  4JC3 A;  1IB1 A;  5IQP A;  3M50 A;  4BG6 A;  4DHP A;  4Y3B A;  3IQV A;  3P1O A;  5HF3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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