2C23A

14-3-3 protein beta (human) in complex with exoenzyme s peptide
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
230
structure length
225
Chain Sequence
MDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Protein-Protein Interactions in the 14-3-3 Protein Family.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords 14-3-3 BETA/ALPHA
total genus 98
structure length 225
sequence length 230
ec nomenclature
pdb deposition date 2005-09-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 2c23A00
4FJ3A 2O02A 5BY9A 5IQPA 3MHRA 2O8PA 2C1JA 3SMMA 5J31A 5EXAA 4J6SA 5BTVA 3P1PA 1O9FA 4DX0A 1O9CA 3SP5A 4DHOA 4ZQ0A 1YZ5A 3AXYC 3UZDA 4DAUA 5D3EA 4O46A 2C63A 4ZDRA 4N7GA 4Y3BA 2BR9A 5HF3A 4N7YA 3RDHA 3UALA 4DNKA 3NKXA 5LU2A 4JC3A 4FR3A 4QLIA 3P1SA 4Y5IA 3O8IA 1QJAA 3IQUA 3P1OA 4DHNA 2C23A 5D2DA 3LW1A 3P1RA 3SMOA 4DHTA 3M50A 1YWTA 1A37A 1QJBA 3T0MA 4DHRA 1A4OA 2BQ0A 2BTPA 1A38A 4F7RA 4DHQA 3P1NA 4BG6A 5LVZA 1O9EA 2O98A 4JDDA 3UX0A 3T0LA 4N84A 3UBWA 1IB1A 5EWZA 5F74A 4Y32A 3SMKA 2WH0A 3SPRA 4DHUA 2V7DA 4IEAA 2C74A 4DATA 3M51A 5D3FA 3CU8A 3SMNA 5LU1A 2C1NA 4FL5A 4GNTA 4WRQA 2B05A 4HKCA 4DHSA 3P1QA 5LX2A 3IQVA 2NPMA 3IQJA 3EFZA 3U9XA 1O9DA 3SMLA 4IHLA 4DHMA 4DHPA 4E2EA 3E6YA 5LHOA
chains in the Genus database with same CATH superfamily
4FJ3A 2O02A 5BY9A 5IQPA 3CQCA 3MHRA 4QX3A 2O8PA 2C1JA 3SMMA 5J31A 5EXAA 4ARYA 4J6SA 5BTVA 3P1PA 1O9FA 4DX0A 1O9CA 3SP5A 4DHOA 4ZQ0A 4QX0A 1YZ5A 3AXYC 3UZDA 4DAUA 5D3EA 4O46A 2C63A 4ZDRA 4N7GA 4Y3BA 2BR9A 5HF3A 4N7YA 3RDHA 3UALA 4DNKA 3NKXA 5LU2A 1URJA 4JC3A 4ARXA 1JI6A 4FR3A 4QLIA 3P1SA 4Y5IA 3O8IA 1QJAA 3IQUA 3P1OA 4DHNA 2C23A 5D2DA 3LW1A 3P1RA 3SMOA 4DHTA 3M50A 1YWTA 1A37A 1QJBA 3T0MA 4DHRA 1A4OA 2BQ0A 2BTPA 1A38A 3CQGA 4F7RA 3X0UA 4DHQA 3P1NA 4BG6A 5LVZA 1O9EA 2O98A 4JDDA 4D8MA 3UX0A 3T0LA 4N84A 4QX1A 3UBWA 3ZHEB 1IB1A 1I5PA 4QX2A 5EWZA 5F74A 1DLCA 4Y32A 3SMKA 2WH0A 3SPRA 4DHUA 2V7DA 4IEAA 2C74A 4DATA 3M51A 5D3FA 3CU8A 3SMNA 5LU1A 2C1NA 4FL5A 4GNTA 1CIYA 1W99A 4WRQA 2B05A 1S2XA 4HKCA 4DHSA 3EB7A 3P1QA 2C9KA 5LX2A 3IQVA 2NPMA 4W8JA 3IQJA 3EFZA 3I4RA 1O9DA 3U9XA 3SMLA 4IHLA 4DHMA 4MOAA 4DHPA 4E2EA 3E6YA 5LHOA
chains in the Genus database with same CATH topology
4FJ3A 2O02A 5BY9A 5IQPA 3MHRA 2O8PA 2C1JA 3SMMA 5J31A 5EXAA 4J6SA 5BTVA 3P1PA 1O9FA 4DX0A 1O9CA 3SP5A 4DHOA 4ZQ0A 1YZ5A 3AXYC 3UZDA 4DAUA 5D3EA 4O46A 2C63A 4ZDRA 4N7GA 4Y3BA 2BR9A 5HF3A 4N7YA 3RDHA 3UALA 4DNKA 3NKXA 5LU2A 4JC3A 4FR3A 4QLIA 3P1SA 4Y5IA 3O8IA 1QJAA 3IQUA 3P1OA 4DHNA 2C23A 5D2DA 3LW1A 3P1RA 3SMOA 4DHTA 3M50A 1YWTA 1A37A 1QJBA 3T0MA 4DHRA 1A4OA 2BQ0A 2BTPA 1A38A 4F7RA 4DHQA 3P1NA 4BG6A 5LVZA 1O9EA 2O98A 4JDDA 3UX0A 3T0LA 4N84A 3UBWA 1IB1A 5EWZA 5F74A 4Y32A 3SMKA 2WH0A 3SPRA 4DHUA 2V7DA 4IEAA 2C74A 4DATA 3M51A 5D3FA 3CU8A 3SMNA 5LU1A 2C1NA 4FL5A 4GNTA 4WRQA 2B05A 4HKCA 4DHSA 3P1QA 5LX2A 3IQVA 2NPMA 3IQJA 3EFZA 3U9XA 1O9DA 3SMLA 4IHLA 4DHMA 4DHPA 4E2EA 3E6YA 5LHOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FJ3 A;  2O02 A;  5BY9 A;  5IQP A;  3MHR A;  2O8P A;  2C1J A;  3SMM A;  5J31 A;  5EXA A;  4J6S A;  5BTV A;  3P1P A;  1O9F A;  4DX0 A;  1O9C A;  3SP5 A;  4DHO A;  4ZQ0 A;  1YZ5 A;  3AXY C;  3UZD A;  4DAU A;  5D3E A;  4O46 A;  2C63 A;  4ZDR A;  4N7G A;  4Y3B A;  2BR9 A;  5HF3 A;  4N7Y A;  3RDH A;  3UAL A;  4DNK A;  3NKX A;  5LU2 A;  4JC3 A;  4FR3 A;  4QLI A;  3P1S A;  4Y5I A;  3O8I A;  1QJA A;  3IQU A;  3P1O A;  4DHN A;  2C23 A;  5D2D A;  3LW1 A;  3P1R A;  3SMO A;  4DHT A;  3M50 A;  1YWT A;  1A37 A;  1QJB A;  3T0M A;  4DHR A;  1A4O A;  2BQ0 A;  2BTP A;  1A38 A;  4F7R A;  4DHQ A;  3P1N A;  4BG6 A;  5LVZ A;  1O9E A;  2O98 A;  4JDD A;  3UX0 A;  3T0L A;  4N84 A;  3UBW A;  1IB1 A;  5EWZ A;  5F74 A;  4Y32 A;  3SMK A;  2WH0 A;  3SPR A;  4DHU A;  2V7D A;  4IEA A;  2C74 A;  4DAT A;  3M51 A;  5D3F A;  3CU8 A;  3SMN A;  5LU1 A;  2C1N A;  4FL5 A;  4GNT A;  4WRQ A;  2B05 A;  4HKC A;  4DHS A;  3P1Q A;  5LX2 A;  3IQV A;  2NPM A;  3IQJ A;  3EFZ A;  3U9X A;  1O9D A;  3SML A;  4IHL A;  4DHM A;  4DHP A;  4E2E A;  3E6Y A;  5LHO A; 
#chains in the Genus database with same CATH topology
 4FJ3 A;  2O02 A;  5BY9 A;  5IQP A;  3CQC A;  3MHR A;  4QX3 A;  2O8P A;  2C1J A;  3SMM A;  5J31 A;  5EXA A;  4ARY A;  4J6S A;  5BTV A;  3P1P A;  1O9F A;  4DX0 A;  1O9C A;  3SP5 A;  4DHO A;  4ZQ0 A;  4QX0 A;  1YZ5 A;  3AXY C;  3UZD A;  4DAU A;  5D3E A;  4O46 A;  2C63 A;  4ZDR A;  4N7G A;  4Y3B A;  2BR9 A;  5HF3 A;  4N7Y A;  3RDH A;  3UAL A;  4DNK A;  3NKX A;  5LU2 A;  1URJ A;  4JC3 A;  4ARX A;  1JI6 A;  4FR3 A;  4QLI A;  3P1S A;  4Y5I A;  3O8I A;  1QJA A;  3IQU A;  3P1O A;  4DHN A;  2C23 A;  5D2D A;  3LW1 A;  3P1R A;  3SMO A;  4DHT A;  3M50 A;  1YWT A;  1A37 A;  1QJB A;  3T0M A;  4DHR A;  1A4O A;  2BQ0 A;  2BTP A;  1A38 A;  3CQG A;  4F7R A;  3X0U A;  4DHQ A;  3P1N A;  4BG6 A;  5LVZ A;  1O9E A;  2O98 A;  4JDD A;  4D8M A;  3UX0 A;  3T0L A;  4N84 A;  4QX1 A;  3UBW A;  3ZHE B;  1IB1 A;  1I5P A;  4QX2 A;  5EWZ A;  5F74 A;  1DLC A;  4Y32 A;  3SMK A;  2WH0 A;  3SPR A;  4DHU A;  2V7D A;  4IEA A;  2C74 A;  4DAT A;  3M51 A;  5D3F A;  3CU8 A;  3SMN A;  5LU1 A;  2C1N A;  4FL5 A;  4GNT A;  1CIY A;  1W99 A;  4WRQ A;  2B05 A;  1S2X A;  4HKC A;  4DHS A;  3EB7 A;  3P1Q A;  2C9K A;  5LX2 A;  3IQV A;  2NPM A;  4W8J A;  3IQJ A;  3EFZ A;  3I4R A;  1O9D A;  3U9X A;  3SML A;  4IHL A;  4DHM A;  4MOA A;  4DHP A;  4E2E A;  3E6Y A;  5LHO A; 
#chains in the Genus database with same CATH homology
 4FJ3 A;  2O02 A;  5BY9 A;  5IQP A;  3MHR A;  2O8P A;  2C1J A;  3SMM A;  5J31 A;  5EXA A;  4J6S A;  5BTV A;  3P1P A;  1O9F A;  4DX0 A;  1O9C A;  3SP5 A;  4DHO A;  4ZQ0 A;  1YZ5 A;  3AXY C;  3UZD A;  4DAU A;  5D3E A;  4O46 A;  2C63 A;  4ZDR A;  4N7G A;  4Y3B A;  2BR9 A;  5HF3 A;  4N7Y A;  3RDH A;  3UAL A;  4DNK A;  3NKX A;  5LU2 A;  4JC3 A;  4FR3 A;  4QLI A;  3P1S A;  4Y5I A;  3O8I A;  1QJA A;  3IQU A;  3P1O A;  4DHN A;  2C23 A;  5D2D A;  3LW1 A;  3P1R A;  3SMO A;  4DHT A;  3M50 A;  1YWT A;  1A37 A;  1QJB A;  3T0M A;  4DHR A;  1A4O A;  2BQ0 A;  2BTP A;  1A38 A;  4F7R A;  4DHQ A;  3P1N A;  4BG6 A;  5LVZ A;  1O9E A;  2O98 A;  4JDD A;  3UX0 A;  3T0L A;  4N84 A;  3UBW A;  1IB1 A;  5EWZ A;  5F74 A;  4Y32 A;  3SMK A;  2WH0 A;  3SPR A;  4DHU A;  2V7D A;  4IEA A;  2C74 A;  4DAT A;  3M51 A;  5D3F A;  3CU8 A;  3SMN A;  5LU1 A;  2C1N A;  4FL5 A;  4GNT A;  4WRQ A;  2B05 A;  4HKC A;  4DHS A;  3P1Q A;  5LX2 A;  3IQV A;  2NPM A;  3IQJ A;  3EFZ A;  3U9X A;  1O9D A;  3SML A;  4IHL A;  4DHM A;  4DHP A;  4E2E A;  3E6Y A;  5LHO A; 
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