1HPJA

Solution nmr structure of the human plasminogen kringle 1 domain complexed with 6-aminohexanoic acid at ph 5.3, 310k, derived from randomly generated structures using simulated annealing, 12 structures
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
79
structure length
79
Chain Sequence
CKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILEC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the epsilon-aminohexanoic acid complex of human plasminogen kringle 1.
pubmed doi rcsb
molecule tags Serine protease
molecule keywords PLASMINOGEN
total genus 10
structure length 79
sequence length 79
ec nomenclature ec 3.4.21.7: Plasmin.
pdb deposition date 1996-08-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00051 Kringle Kringle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.20.10 Mainly Beta Beta Barrel Plasminogen Kringle 4 Plasminogen Kringle 4 1hpjA00
1GMOA 1HPKA 5CT1A 2HPQP 1BHTA 4D3CA 2DOHX 1URKA 1KI0A 2K4RA 1NK1A 1B2IA 1TPKA 2I9AA 5COEA 4A5TS 1A0HA 2QJ2A 1PMKA 4DURA 5CT3A 4BVVA 3BT2A 4HZHA 2PK4A 2I9BA 5CS3A 2KNFA 2PF2A 4BV7A 5CS5A 2PF1A 5CP9A 1GP9A 1I5KA 3SP8A 4BVDA 4CIKA 3NXPA 1PMLA 3MKPA 2KJ4A 1GMNA 1JFNA 4BVCA 4IUAA 5CT2A 2SPTA 3K65A 5CSQA 5CS9A 1CEBA 3U73A 2DOIA 4KIVA 1PKRA 1KRNA 1KIVA 5HPGA 1CEAA 1HPJA 4NZQA 1NL1A 3E6PL 5CS1A 2FD6A 2QJ4A 4BVWA 3LAQA 2FEBA 3KIVA 1PK2A 3BT1A 2L0SA 3HN4A 4O03A 4BV5A 1NL2A 2K51A 1KDUA 2HPPP 1I71A 1PK4A
chains in the Genus database with same CATH superfamily
1GMOA 1HPKA 5CT1A 2HPQP 1BHTA 4D3CA 2DOHX 1URKA 1KI0A 2K4RA 1NK1A 1B2IA 1TPKA 2I9AA 5COEA 4A5TS 1A0HA 2QJ2A 1PMKA 4DURA 5CT3A 4BVVA 3BT2A 4HZHA 2PK4A 2I9BA 5CS3A 2KNFA 2PF2A 4BV7A 5CS5A 2PF1A 5CP9A 1GP9A 1I5KA 3SP8A 4BVDA 4CIKA 3NXPA 1PMLA 3MKPA 2KJ4A 1GMNA 1JFNA 4BVCA 4IUAA 5CT2A 2SPTA 3K65A 5CSQA 5CS9A 1CEBA 3U73A 2DOIA 4KIVA 1PKRA 1KRNA 1KIVA 5HPGA 1CEAA 1HPJA 4NZQA 1NL1A 3E6PL 5CS1A 2FD6A 2QJ4A 4BVWA 3LAQA 2FEBA 3KIVA 1PK2A 3BT1A 2L0SA 3HN4A 4O03A 4BV5A 1NL2A 2K51A 1KDUA 2HPPP 1I71A 1PK4A
chains in the Genus database with same CATH topology
1GMOA 1HPKA 5CT1A 2HPQP 1BHTA 4D3CA 2DOHX 1URKA 1KI0A 2K4RA 1NK1A 1B2IA 1TPKA 2I9AA 5COEA 4A5TS 1A0HA 2QJ2A 1PMKA 4DURA 5CT3A 4BVVA 3BT2A 4HZHA 2PK4A 2I9BA 5CS3A 2KNFA 2PF2A 4BV7A 5CS5A 2PF1A 5CP9A 1GP9A 1I5KA 3SP8A 4BVDA 4CIKA 3NXPA 1PMLA 3MKPA 2KJ4A 1GMNA 1JFNA 4BVCA 4IUAA 5CT2A 2SPTA 3K65A 5CSQA 5CS9A 1CEBA 3U73A 2DOIA 4KIVA 1PKRA 1KRNA 1KIVA 5HPGA 1CEAA 1HPJA 4NZQA 1NL1A 3E6PL 5CS1A 2FD6A 2QJ4A 4BVWA 3LAQA 2FEBA 3KIVA 1PK2A 3BT1A 2L0SA 3HN4A 4O03A 4BV5A 1NL2A 2K51A 1KDUA 2HPPP 1I71A 1PK4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GMO A;  1HPK A;  5CT1 A;  2HPQ P;  1BHT A;  4D3C A;  2DOH X;  1URK A;  1KI0 A;  2K4R A;  1NK1 A;  1B2I A;  1TPK A;  2I9A A;  5COE A;  4A5T S;  1A0H A;  2QJ2 A;  1PMK A;  4DUR A;  5CT3 A;  4BVV A;  3BT2 A;  4HZH A;  2PK4 A;  2I9B A;  5CS3 A;  2KNF A;  2PF2 A;  4BV7 A;  5CS5 A;  2PF1 A;  5CP9 A;  1GP9 A;  1I5K A;  3SP8 A;  4BVD A;  4CIK A;  3NXP A;  1PML A;  3MKP A;  2KJ4 A;  1GMN A;  1JFN A;  4BVC A;  4IUA A;  5CT2 A;  2SPT A;  3K65 A;  5CSQ A;  5CS9 A;  1CEB A;  3U73 A;  2DOI A;  4KIV A;  1PKR A;  1KRN A;  1KIV A;  5HPG A;  1CEA A;  1HPJ A;  4NZQ A;  1NL1 A;  3E6P L;  5CS1 A;  2FD6 A;  2QJ4 A;  4BVW A;  3LAQ A;  2FEB A;  3KIV A;  1PK2 A;  3BT1 A;  2L0S A;  3HN4 A;  4O03 A;  4BV5 A;  1NL2 A;  2K51 A;  1KDU A;  2HPP P;  1I71 A;  1PK4 A; 
#chains in the Genus database with same CATH topology
 1GMO A;  1HPK A;  5CT1 A;  2HPQ P;  1BHT A;  4D3C A;  2DOH X;  1URK A;  1KI0 A;  2K4R A;  1NK1 A;  1B2I A;  1TPK A;  2I9A A;  5COE A;  4A5T S;  1A0H A;  2QJ2 A;  1PMK A;  4DUR A;  5CT3 A;  4BVV A;  3BT2 A;  4HZH A;  2PK4 A;  2I9B A;  5CS3 A;  2KNF A;  2PF2 A;  4BV7 A;  5CS5 A;  2PF1 A;  5CP9 A;  1GP9 A;  1I5K A;  3SP8 A;  4BVD A;  4CIK A;  3NXP A;  1PML A;  3MKP A;  2KJ4 A;  1GMN A;  1JFN A;  4BVC A;  4IUA A;  5CT2 A;  2SPT A;  3K65 A;  5CSQ A;  5CS9 A;  1CEB A;  3U73 A;  2DOI A;  4KIV A;  1PKR A;  1KRN A;  1KIV A;  5HPG A;  1CEA A;  1HPJ A;  4NZQ A;  1NL1 A;  3E6P L;  5CS1 A;  2FD6 A;  2QJ4 A;  4BVW A;  3LAQ A;  2FEB A;  3KIV A;  1PK2 A;  3BT1 A;  2L0S A;  3HN4 A;  4O03 A;  4BV5 A;  1NL2 A;  2K51 A;  1KDU A;  2HPP P;  1I71 A;  1PK4 A; 
#chains in the Genus database with same CATH homology
 1GMO A;  1HPK A;  5CT1 A;  2HPQ P;  1BHT A;  4D3C A;  2DOH X;  1URK A;  1KI0 A;  2K4R A;  1NK1 A;  1B2I A;  1TPK A;  2I9A A;  5COE A;  4A5T S;  1A0H A;  2QJ2 A;  1PMK A;  4DUR A;  5CT3 A;  4BVV A;  3BT2 A;  4HZH A;  2PK4 A;  2I9B A;  5CS3 A;  2KNF A;  2PF2 A;  4BV7 A;  5CS5 A;  2PF1 A;  5CP9 A;  1GP9 A;  1I5K A;  3SP8 A;  4BVD A;  4CIK A;  3NXP A;  1PML A;  3MKP A;  2KJ4 A;  1GMN A;  1JFN A;  4BVC A;  4IUA A;  5CT2 A;  2SPT A;  3K65 A;  5CSQ A;  5CS9 A;  1CEB A;  3U73 A;  2DOI A;  4KIV A;  1PKR A;  1KRN A;  1KIV A;  5HPG A;  1CEA A;  1HPJ A;  4NZQ A;  1NL1 A;  3E6P L;  5CS1 A;  2FD6 A;  2QJ4 A;  4BVW A;  3LAQ A;  2FEB A;  3KIV A;  1PK2 A;  3BT1 A;  2L0S A;  3HN4 A;  4O03 A;  4BV5 A;  1NL2 A;  2K51 A;  1KDU A;  2HPP P;  1I71 A;  1PK4 A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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