1HPJA

Solution nmr structure of the human plasminogen kringle 1 domain complexed with 6-aminohexanoic acid at ph 5.3, 310k, derived from randomly generated structures using simulated annealing, 12 structures
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
79
structure length
79
Chain Sequence
CKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILEC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the epsilon-aminohexanoic acid complex of human plasminogen kringle 1.
pubmed doi rcsb
molecule keywords PLASMINOGEN
molecule tags Serine protease
total genus 10
structure length 79
sequence length 79
ec nomenclature ec 3.4.21.7: Plasmin.
pdb deposition date 1996-08-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00051 Kringle Kringle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.20.10 Mainly Beta Beta Barrel Plasminogen Kringle 4 Plasminogen Kringle 4 1hpjA00
1A0HA 3SP8A 4HZHA 4BVDA 2PK4A 1KDUA 1I71A 5CSQA 4BV7A 4BV5A 1GMOA 4IUAA 2I9BA 5CS1A 1PKRA 1URKA 1KRNA 4BVVA 1PMKA 3MKPA 1GMNA 1NK1A 2DOIA 5CS9A 5CS5A 2DOHX 4NZQA 4KIVA 2I9AA 2PF2A 2HPQP 1CEBA 1TPKA 4O03A 2L0SA 5HPGA 4D3CA 1PK4A 2K4RA 3LAQA 3U73A 2SPTA 4DURA 3BT1A 5CT3A 3K65A 3BT2A 1BHTA 2PF1A 3NXPA 3HN4A 1GP9A 5CS3A 5CT2A 1NL2A 1KI0A 1HPKA 1JFNA 1B2IA 2QJ4A 4BVCA 1CEAA 2QJ2A 2KNFA 2KJ4A 4A5TS 4BVWA 3E6PL 1HPJA 3KIVA 1NL1A 1PK2A 1KIVA 1PMLA 2FD6A 5CP9A 5COEA 2FEBA 1I5KA 5CT1A 2K51A 4CIKA 2HPPP
chains in the Genus database with same CATH superfamily
1A0HA 3SP8A 4HZHA 4BVDA 2PK4A 1KDUA 1I71A 5CSQA 4BV7A 4BV5A 1GMOA 4IUAA 2I9BA 5CS1A 1PKRA 1URKA 1KRNA 4BVVA 1PMKA 3MKPA 1GMNA 1NK1A 2DOIA 5CS9A 5CS5A 2DOHX 4NZQA 4KIVA 2I9AA 2PF2A 2HPQP 1CEBA 1TPKA 4O03A 2L0SA 5HPGA 4D3CA 1PK4A 2K4RA 3LAQA 3U73A 2SPTA 4DURA 3BT1A 5CT3A 3K65A 3BT2A 1BHTA 2PF1A 3NXPA 3HN4A 1GP9A 5CS3A 5CT2A 1NL2A 1KI0A 1HPKA 1JFNA 1B2IA 2QJ4A 4BVCA 1CEAA 2QJ2A 2KNFA 2KJ4A 4A5TS 4BVWA 3E6PL 1HPJA 3KIVA 1NL1A 1PK2A 1KIVA 1PMLA 2FD6A 5CP9A 5COEA 2FEBA 1I5KA 5CT1A 2K51A 4CIKA 2HPPP
chains in the Genus database with same CATH topology
1A0HA 3SP8A 4HZHA 4BVDA 2PK4A 1KDUA 1I71A 5CSQA 4BV7A 4BV5A 1GMOA 4IUAA 2I9BA 5CS1A 1PKRA 1URKA 1KRNA 4BVVA 1PMKA 3MKPA 1GMNA 1NK1A 2DOIA 5CS9A 5CS5A 2DOHX 4NZQA 4KIVA 2I9AA 2PF2A 2HPQP 1CEBA 1TPKA 4O03A 2L0SA 5HPGA 4D3CA 1PK4A 2K4RA 3LAQA 3U73A 2SPTA 4DURA 3BT1A 5CT3A 3K65A 3BT2A 1BHTA 2PF1A 3NXPA 3HN4A 1GP9A 5CS3A 5CT2A 1NL2A 1KI0A 1HPKA 1JFNA 1B2IA 2QJ4A 4BVCA 1CEAA 2QJ2A 2KNFA 2KJ4A 4A5TS 4BVWA 3E6PL 1HPJA 3KIVA 1NL1A 1PK2A 1KIVA 1PMLA 2FD6A 5CP9A 5COEA 2FEBA 1I5KA 5CT1A 2K51A 4CIKA 2HPPP
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1A0H A;  3SP8 A;  4HZH A;  4BVD A;  2PK4 A;  1KDU A;  1I71 A;  5CSQ A;  4BV7 A;  4BV5 A;  1GMO A;  4IUA A;  2I9B A;  5CS1 A;  1PKR A;  1URK A;  1KRN A;  4BVV A;  1PMK A;  3MKP A;  1GMN A;  1NK1 A;  2DOI A;  5CS9 A;  5CS5 A;  2DOH X;  4NZQ A;  4KIV A;  2I9A A;  2PF2 A;  2HPQ P;  1CEB A;  1TPK A;  4O03 A;  2L0S A;  5HPG A;  4D3C A;  1PK4 A;  2K4R A;  3LAQ A;  3U73 A;  2SPT A;  4DUR A;  3BT1 A;  5CT3 A;  3K65 A;  3BT2 A;  1BHT A;  2PF1 A;  3NXP A;  3HN4 A;  1GP9 A;  5CS3 A;  5CT2 A;  1NL2 A;  1KI0 A;  1HPK A;  1JFN A;  1B2I A;  2QJ4 A;  4BVC A;  1CEA A;  2QJ2 A;  2KNF A;  2KJ4 A;  4A5T S;  4BVW A;  3E6P L;  1HPJ A;  3KIV A;  1NL1 A;  1PK2 A;  1KIV A;  1PML A;  2FD6 A;  5CP9 A;  5COE A;  2FEB A;  1I5K A;  5CT1 A;  2K51 A;  4CIK A;  2HPP P; 
#chains in the Genus database with same CATH topology
 1A0H A;  3SP8 A;  4HZH A;  4BVD A;  2PK4 A;  1KDU A;  1I71 A;  5CSQ A;  4BV7 A;  4BV5 A;  1GMO A;  4IUA A;  2I9B A;  5CS1 A;  1PKR A;  1URK A;  1KRN A;  4BVV A;  1PMK A;  3MKP A;  1GMN A;  1NK1 A;  2DOI A;  5CS9 A;  5CS5 A;  2DOH X;  4NZQ A;  4KIV A;  2I9A A;  2PF2 A;  2HPQ P;  1CEB A;  1TPK A;  4O03 A;  2L0S A;  5HPG A;  4D3C A;  1PK4 A;  2K4R A;  3LAQ A;  3U73 A;  2SPT A;  4DUR A;  3BT1 A;  5CT3 A;  3K65 A;  3BT2 A;  1BHT A;  2PF1 A;  3NXP A;  3HN4 A;  1GP9 A;  5CS3 A;  5CT2 A;  1NL2 A;  1KI0 A;  1HPK A;  1JFN A;  1B2I A;  2QJ4 A;  4BVC A;  1CEA A;  2QJ2 A;  2KNF A;  2KJ4 A;  4A5T S;  4BVW A;  3E6P L;  1HPJ A;  3KIV A;  1NL1 A;  1PK2 A;  1KIV A;  1PML A;  2FD6 A;  5CP9 A;  5COE A;  2FEB A;  1I5K A;  5CT1 A;  2K51 A;  4CIK A;  2HPP P; 
#chains in the Genus database with same CATH homology
 1A0H A;  3SP8 A;  4HZH A;  4BVD A;  2PK4 A;  1KDU A;  1I71 A;  5CSQ A;  4BV7 A;  4BV5 A;  1GMO A;  4IUA A;  2I9B A;  5CS1 A;  1PKR A;  1URK A;  1KRN A;  4BVV A;  1PMK A;  3MKP A;  1GMN A;  1NK1 A;  2DOI A;  5CS9 A;  5CS5 A;  2DOH X;  4NZQ A;  4KIV A;  2I9A A;  2PF2 A;  2HPQ P;  1CEB A;  1TPK A;  4O03 A;  2L0S A;  5HPG A;  4D3C A;  1PK4 A;  2K4R A;  3LAQ A;  3U73 A;  2SPT A;  4DUR A;  3BT1 A;  5CT3 A;  3K65 A;  3BT2 A;  1BHT A;  2PF1 A;  3NXP A;  3HN4 A;  1GP9 A;  5CS3 A;  5CT2 A;  1NL2 A;  1KI0 A;  1HPK A;  1JFN A;  1B2I A;  2QJ4 A;  4BVC A;  1CEA A;  2QJ2 A;  2KNF A;  2KJ4 A;  4A5T S;  4BVW A;  3E6P L;  1HPJ A;  3KIV A;  1NL1 A;  1PK2 A;  1KIV A;  1PML A;  2FD6 A;  5CP9 A;  5COE A;  2FEB A;  1I5K A;  5CT1 A;  2K51 A;  4CIK A;  2HPP P; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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