1KI0A

The x-ray structure of human angiostatin
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
253
structure length
253
Chain Sequence
LSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILECEEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHERTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Homo sapiens
publication title The X-ray crystallographic structure of the angiogenesis inhibitor angiostatin.
pubmed doi rcsb
molecule keywords ANGIOSTATIN
total genus 58
structure length 253
sequence length 253
ec nomenclature ec 3.4.21.7: Plasmin.
pdb deposition date 2001-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00051 Kringle Kringle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.20.10 Mainly Beta Beta Barrel Plasminogen Kringle 4 Plasminogen Kringle 4 1ki0A02
2.40.20.10 Mainly Beta Beta Barrel Plasminogen Kringle 4 Plasminogen Kringle 4 1ki0A03
2.40.20.10 Mainly Beta Beta Barrel Plasminogen Kringle 4 Plasminogen Kringle 4 1ki0A01
1JFNA 1B2IA 1NL1A 1PK2A 1GP9A 5CS3A 2K51A 4HZHA 2DOHX 4BVVA 2PF1A 2L0SA 4BV7A 3SP8A 2HPPP 5COEA 3K65A 5CSQA 5CT1A 2KNFA 5CT2A 2FD6A 2SPTA 5HPGA 2HPQP 2PF2A 4BV5A 2FEBA 4NZQA 2DOIA 5CS1A 2PK4A 4DURA 1GMOA 1A0HA 4IUAA 1I5KA 5CS5A 3MKPA 1NK1A 1HPKA 1NL2A 3BT1A 3BT2A 1PK4A 4KIVA 1KDUA 1URKA 5CT3A 4CIKA 2QJ4A 3KIVA 1CEBA 1HPJA 4O03A 4BVDA 1PMKA 3LAQA 4BVCA 1PMLA 1PKRA 1KI0A 1KIVA 5CS9A 1TPKA 3NXPA 2KJ4A 1I71A 3HN4A 1KRNA 4BVWA 2I9BA 2K4RA 1GMNA 4D3CA 1BHTA 4A5TS 1CEAA 5CP9A 2I9AA 3E6PL 3U73A 2QJ2A
chains in the Genus database with same CATH superfamily
1JFNA 1B2IA 1NL1A 1PK2A 1GP9A 5CS3A 2K51A 4HZHA 2DOHX 4BVVA 2PF1A 2L0SA 4BV7A 3SP8A 2HPPP 5COEA 3K65A 5CSQA 5CT1A 2KNFA 5CT2A 2FD6A 2SPTA 5HPGA 2HPQP 2PF2A 4BV5A 2FEBA 4NZQA 2DOIA 5CS1A 2PK4A 4DURA 1GMOA 1A0HA 4IUAA 1I5KA 5CS5A 3MKPA 1NK1A 1HPKA 1NL2A 3BT1A 3BT2A 1PK4A 4KIVA 1KDUA 1URKA 5CT3A 4CIKA 2QJ4A 3KIVA 1CEBA 1HPJA 4O03A 4BVDA 1PMKA 3LAQA 4BVCA 1PMLA 1PKRA 1KI0A 1KIVA 5CS9A 1TPKA 3NXPA 2KJ4A 1I71A 3HN4A 1KRNA 4BVWA 2I9BA 2K4RA 1GMNA 4D3CA 1BHTA 4A5TS 1CEAA 5CP9A 2I9AA 3E6PL 3U73A 2QJ2A
chains in the Genus database with same CATH topology
1JFNA 1B2IA 1NL1A 1PK2A 1GP9A 5CS3A 2K51A 4HZHA 2DOHX 4BVVA 2PF1A 2L0SA 4BV7A 3SP8A 2HPPP 5COEA 3K65A 5CSQA 5CT1A 2KNFA 5CT2A 2FD6A 2SPTA 5HPGA 2HPQP 2PF2A 4BV5A 2FEBA 4NZQA 2DOIA 5CS1A 2PK4A 4DURA 1GMOA 1A0HA 4IUAA 1I5KA 5CS5A 3MKPA 1NK1A 1HPKA 1NL2A 3BT1A 3BT2A 1PK4A 4KIVA 1KDUA 1URKA 5CT3A 4CIKA 2QJ4A 3KIVA 1CEBA 1HPJA 4O03A 4BVDA 1PMKA 3LAQA 4BVCA 1PMLA 1PKRA 1KI0A 1KIVA 5CS9A 1TPKA 3NXPA 2KJ4A 1I71A 3HN4A 1KRNA 4BVWA 2I9BA 2K4RA 1GMNA 4D3CA 1BHTA 4A5TS 1CEAA 5CP9A 2I9AA 3E6PL 3U73A 2QJ2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JFN A;  1B2I A;  1NL1 A;  1PK2 A;  1GP9 A;  5CS3 A;  2K51 A;  4HZH A;  2DOH X;  4BVV A;  2PF1 A;  2L0S A;  4BV7 A;  3SP8 A;  2HPP P;  5COE A;  3K65 A;  5CSQ A;  5CT1 A;  2KNF A;  5CT2 A;  2FD6 A;  2SPT A;  5HPG A;  2HPQ P;  2PF2 A;  4BV5 A;  2FEB A;  4NZQ A;  2DOI A;  5CS1 A;  2PK4 A;  4DUR A;  1GMO A;  1A0H A;  4IUA A;  1I5K A;  5CS5 A;  3MKP A;  1NK1 A;  1HPK A;  1NL2 A;  3BT1 A;  3BT2 A;  1PK4 A;  4KIV A;  1KDU A;  1URK A;  5CT3 A;  4CIK A;  2QJ4 A;  3KIV A;  1CEB A;  1HPJ A;  4O03 A;  4BVD A;  1PMK A;  3LAQ A;  4BVC A;  1PML A;  1PKR A;  1KI0 A;  1KIV A;  5CS9 A;  1TPK A;  3NXP A;  2KJ4 A;  1I71 A;  3HN4 A;  1KRN A;  4BVW A;  2I9B A;  2K4R A;  1GMN A;  4D3C A;  1BHT A;  4A5T S;  1CEA A;  5CP9 A;  2I9A A;  3E6P L;  3U73 A;  2QJ2 A; 
#chains in the Genus database with same CATH topology
 1JFN A;  1B2I A;  1NL1 A;  1PK2 A;  1GP9 A;  5CS3 A;  2K51 A;  4HZH A;  2DOH X;  4BVV A;  2PF1 A;  2L0S A;  4BV7 A;  3SP8 A;  2HPP P;  5COE A;  3K65 A;  5CSQ A;  5CT1 A;  2KNF A;  5CT2 A;  2FD6 A;  2SPT A;  5HPG A;  2HPQ P;  2PF2 A;  4BV5 A;  2FEB A;  4NZQ A;  2DOI A;  5CS1 A;  2PK4 A;  4DUR A;  1GMO A;  1A0H A;  4IUA A;  1I5K A;  5CS5 A;  3MKP A;  1NK1 A;  1HPK A;  1NL2 A;  3BT1 A;  3BT2 A;  1PK4 A;  4KIV A;  1KDU A;  1URK A;  5CT3 A;  4CIK A;  2QJ4 A;  3KIV A;  1CEB A;  1HPJ A;  4O03 A;  4BVD A;  1PMK A;  3LAQ A;  4BVC A;  1PML A;  1PKR A;  1KI0 A;  1KIV A;  5CS9 A;  1TPK A;  3NXP A;  2KJ4 A;  1I71 A;  3HN4 A;  1KRN A;  4BVW A;  2I9B A;  2K4R A;  1GMN A;  4D3C A;  1BHT A;  4A5T S;  1CEA A;  5CP9 A;  2I9A A;  3E6P L;  3U73 A;  2QJ2 A; 
#chains in the Genus database with same CATH homology
 1JFN A;  1B2I A;  1NL1 A;  1PK2 A;  1GP9 A;  5CS3 A;  2K51 A;  4HZH A;  2DOH X;  4BVV A;  2PF1 A;  2L0S A;  4BV7 A;  3SP8 A;  2HPP P;  5COE A;  3K65 A;  5CSQ A;  5CT1 A;  2KNF A;  5CT2 A;  2FD6 A;  2SPT A;  5HPG A;  2HPQ P;  2PF2 A;  4BV5 A;  2FEB A;  4NZQ A;  2DOI A;  5CS1 A;  2PK4 A;  4DUR A;  1GMO A;  1A0H A;  4IUA A;  1I5K A;  5CS5 A;  3MKP A;  1NK1 A;  1HPK A;  1NL2 A;  3BT1 A;  3BT2 A;  1PK4 A;  4KIV A;  1KDU A;  1URK A;  5CT3 A;  4CIK A;  2QJ4 A;  3KIV A;  1CEB A;  1HPJ A;  4O03 A;  4BVD A;  1PMK A;  3LAQ A;  4BVC A;  1PML A;  1PKR A;  1KI0 A;  1KIV A;  5CS9 A;  1TPK A;  3NXP A;  2KJ4 A;  1I71 A;  3HN4 A;  1KRN A;  4BVW A;  2I9B A;  2K4R A;  1GMN A;  4D3C A;  1BHT A;  4A5T S;  1CEA A;  5CP9 A;  2I9A A;  3E6P L;  3U73 A;  2QJ2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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