1I5KA

Structure and binding determinants of the recombinant kringle-2 domain of human plasminogen to an internal peptide from a group a streptococcal surface protein
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
79
structure length
79
Chain Sequence
ECMHGSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRDLRPWCFTTDPNKRWEYCDIPRC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and binding determinants of the recombinant kringle-2 domain of human plasminogen to an internal peptide from a group A Streptococcal surface protein.
pubmed doi rcsb
molecule tags Blood clotting
source organism Homo sapiens
molecule keywords PLASMINOGEN
total genus 19
structure length 79
sequence length 79
chains with identical sequence B
ec nomenclature ec 3.4.21.7: Plasmin.
pdb deposition date 2001-02-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00051 Kringle Kringle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.20.10 Mainly Beta Beta Barrel Plasminogen Kringle 4 Plasminogen Kringle 4 1i5kA00
1JFNA 2QJ2A 4BV7A 4BVCA 4BVVA 2KJ4A 1GMOA 1NL2A 1BHTA 4BV5A 3KIVA 2I9BA 5CT1A 2PF1A 5COEA 4O03A 1I5KA 1NK1A 5HPGA 2K4RA 1URKA 1PK4A 1NL1A 3HN4A 2HPQP 1HPKA 2FD6A 5CT3A 4DURA 3BT2A 1KIVA 3MKPA 2KNFA 2DOHX 1CEAA 3BT1A 2SPTA 4NZQA 5CS9A 3E6PL 3NXPA 1HPJA 2DOIA 2I9AA 1PMKA 1I71A 3SP8A 4IUAA 5CSQA 1CEBA 2FEBA 2PK4A 1A0HA 1GP9A 5CT2A 3U73A 1KDUA 2HPPP 3K65A 3LAQA 4HZHA 1GMNA 2QJ4A 5CS1A 5CS5A 2L0SA 1KRNA 5CS3A 4BVWA 4CIKA 4A5TS 1B2IA 1PK2A 1TPKA 2PF2A 4D3CA 4BVDA 1PMLA 2K51A 1KI0A 4KIVA 5CP9A 1PKRA
chains in the Genus database with same CATH superfamily
1JFNA 2QJ2A 4BV7A 4BVCA 4BVVA 2KJ4A 1GMOA 1NL2A 1BHTA 4BV5A 3KIVA 2I9BA 5CT1A 2PF1A 5COEA 4O03A 1I5KA 1NK1A 5HPGA 2K4RA 1URKA 1PK4A 1NL1A 3HN4A 2HPQP 1HPKA 2FD6A 5CT3A 4DURA 3BT2A 1KIVA 3MKPA 2KNFA 2DOHX 1CEAA 3BT1A 2SPTA 4NZQA 5CS9A 3E6PL 3NXPA 1HPJA 2DOIA 2I9AA 1PMKA 1I71A 3SP8A 4IUAA 5CSQA 1CEBA 2FEBA 2PK4A 1A0HA 1GP9A 5CT2A 3U73A 1KDUA 2HPPP 3K65A 3LAQA 4HZHA 1GMNA 2QJ4A 5CS1A 5CS5A 2L0SA 1KRNA 5CS3A 4BVWA 4CIKA 4A5TS 1B2IA 1PK2A 1TPKA 2PF2A 4D3CA 4BVDA 1PMLA 2K51A 1KI0A 4KIVA 5CP9A 1PKRA
chains in the Genus database with same CATH topology
1JFNA 2QJ2A 4BV7A 4BVCA 4BVVA 2KJ4A 1GMOA 1NL2A 1BHTA 4BV5A 3KIVA 2I9BA 5CT1A 2PF1A 5COEA 4O03A 1I5KA 1NK1A 5HPGA 2K4RA 1URKA 1PK4A 1NL1A 3HN4A 2HPQP 1HPKA 2FD6A 5CT3A 4DURA 3BT2A 1KIVA 3MKPA 2KNFA 2DOHX 1CEAA 3BT1A 2SPTA 4NZQA 5CS9A 3E6PL 3NXPA 1HPJA 2DOIA 2I9AA 1PMKA 1I71A 3SP8A 4IUAA 5CSQA 1CEBA 2FEBA 2PK4A 1A0HA 1GP9A 5CT2A 3U73A 1KDUA 2HPPP 3K65A 3LAQA 4HZHA 1GMNA 2QJ4A 5CS1A 5CS5A 2L0SA 1KRNA 5CS3A 4BVWA 4CIKA 4A5TS 1B2IA 1PK2A 1TPKA 2PF2A 4D3CA 4BVDA 1PMLA 2K51A 1KI0A 4KIVA 5CP9A 1PKRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JFN A;  2QJ2 A;  4BV7 A;  4BVC A;  4BVV A;  2KJ4 A;  1GMO A;  1NL2 A;  1BHT A;  4BV5 A;  3KIV A;  2I9B A;  5CT1 A;  2PF1 A;  5COE A;  4O03 A;  1I5K A;  1NK1 A;  5HPG A;  2K4R A;  1URK A;  1PK4 A;  1NL1 A;  3HN4 A;  2HPQ P;  1HPK A;  2FD6 A;  5CT3 A;  4DUR A;  3BT2 A;  1KIV A;  3MKP A;  2KNF A;  2DOH X;  1CEA A;  3BT1 A;  2SPT A;  4NZQ A;  5CS9 A;  3E6P L;  3NXP A;  1HPJ A;  2DOI A;  2I9A A;  1PMK A;  1I71 A;  3SP8 A;  4IUA A;  5CSQ A;  1CEB A;  2FEB A;  2PK4 A;  1A0H A;  1GP9 A;  5CT2 A;  3U73 A;  1KDU A;  2HPP P;  3K65 A;  3LAQ A;  4HZH A;  1GMN A;  2QJ4 A;  5CS1 A;  5CS5 A;  2L0S A;  1KRN A;  5CS3 A;  4BVW A;  4CIK A;  4A5T S;  1B2I A;  1PK2 A;  1TPK A;  2PF2 A;  4D3C A;  4BVD A;  1PML A;  2K51 A;  1KI0 A;  4KIV A;  5CP9 A;  1PKR A; 
#chains in the Genus database with same CATH topology
 1JFN A;  2QJ2 A;  4BV7 A;  4BVC A;  4BVV A;  2KJ4 A;  1GMO A;  1NL2 A;  1BHT A;  4BV5 A;  3KIV A;  2I9B A;  5CT1 A;  2PF1 A;  5COE A;  4O03 A;  1I5K A;  1NK1 A;  5HPG A;  2K4R A;  1URK A;  1PK4 A;  1NL1 A;  3HN4 A;  2HPQ P;  1HPK A;  2FD6 A;  5CT3 A;  4DUR A;  3BT2 A;  1KIV A;  3MKP A;  2KNF A;  2DOH X;  1CEA A;  3BT1 A;  2SPT A;  4NZQ A;  5CS9 A;  3E6P L;  3NXP A;  1HPJ A;  2DOI A;  2I9A A;  1PMK A;  1I71 A;  3SP8 A;  4IUA A;  5CSQ A;  1CEB A;  2FEB A;  2PK4 A;  1A0H A;  1GP9 A;  5CT2 A;  3U73 A;  1KDU A;  2HPP P;  3K65 A;  3LAQ A;  4HZH A;  1GMN A;  2QJ4 A;  5CS1 A;  5CS5 A;  2L0S A;  1KRN A;  5CS3 A;  4BVW A;  4CIK A;  4A5T S;  1B2I A;  1PK2 A;  1TPK A;  2PF2 A;  4D3C A;  4BVD A;  1PML A;  2K51 A;  1KI0 A;  4KIV A;  5CP9 A;  1PKR A; 
#chains in the Genus database with same CATH homology
 1JFN A;  2QJ2 A;  4BV7 A;  4BVC A;  4BVV A;  2KJ4 A;  1GMO A;  1NL2 A;  1BHT A;  4BV5 A;  3KIV A;  2I9B A;  5CT1 A;  2PF1 A;  5COE A;  4O03 A;  1I5K A;  1NK1 A;  5HPG A;  2K4R A;  1URK A;  1PK4 A;  1NL1 A;  3HN4 A;  2HPQ P;  1HPK A;  2FD6 A;  5CT3 A;  4DUR A;  3BT2 A;  1KIV A;  3MKP A;  2KNF A;  2DOH X;  1CEA A;  3BT1 A;  2SPT A;  4NZQ A;  5CS9 A;  3E6P L;  3NXP A;  1HPJ A;  2DOI A;  2I9A A;  1PMK A;  1I71 A;  3SP8 A;  4IUA A;  5CSQ A;  1CEB A;  2FEB A;  2PK4 A;  1A0H A;  1GP9 A;  5CT2 A;  3U73 A;  1KDU A;  2HPP P;  3K65 A;  3LAQ A;  4HZH A;  1GMN A;  2QJ4 A;  5CS1 A;  5CS5 A;  2L0S A;  1KRN A;  5CS3 A;  4BVW A;  4CIK A;  4A5T S;  1B2I A;  1PK2 A;  1TPK A;  2PF2 A;  4D3C A;  4BVD A;  1PML A;  2K51 A;  1KI0 A;  4KIV A;  5CP9 A;  1PKR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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