1ME5A

Crystal structure of mycobacterium tuberculosis alkylperoxidase ahpd h132q mutant
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
173
structure length
173
Chain Sequence
IEKLKAALPEYAKDIKLNLSSITRSSVLDQEQLWGTLLASAAATRNPQVLADIGAEATDHLSAAARHAALGAAAIMGMNNVFYRGRGFLEGRYDDLRPGLRMNIIANPGIPKANFELWSFAVSAINGCSQCLVAHEHTLRTVGVDREAIFEALKAAAIVSGVAQALATIEALS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The mechanism of Mycobacterium tuberculosis alkylhydroperoxidase AhpD as defined by mutagenesis, crystallography, and kinetics.
pubmed doi rcsb
molecule keywords ALKYLHYDROPEROXIDASE D
molecule tags Oxidoreductase
source organism Mycobacterium tuberculosis
total genus 57
structure length 173
sequence length 173
chains with identical sequence B, C
ec nomenclature ec 1.11.1.15: Peroxiredoxin.
pdb deposition date 2002-08-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02627 CMD Carboxymuconolactone decarboxylase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.10 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 1me5A00
2AF7A 2OYOA 2IJCA 1KNCA 1VKEA 1ME5A 2Q0TA 2QEUA 3D7IA 3BEYA 2OUWA 2PFXA 1P8CA 2O4DA 5DIKA 2CWQA 3LVYA 4G9QA 2PRRA 1LW1A 2GMYA 3C1LA 1GU9A 5DIPA
chains in the Genus database with same CATH superfamily
2AF7A 3AA1A 2OYOA 2IJCA 1KNCA 2JN8A 4AKRA 1VKEA 1ME5A 2Q0TA 2KXPA 2QEUA 3AAAA 3BEYA 3D7IA 2OUWA 3LK41 2PFXA 1P8CA 2O4DA 5DIKA 2CWQA 5ADXK 3LVYA 2ES9A 4G9QA 2PRRA 3AAEA 3AA0A 2KZ7A 3LK3A 3AA7A 1LW1A 3LK2A 3AA6A 2GMYA 5AFUK 3C1LA 1IZNA 1GU9A 5DIPA
chains in the Genus database with same CATH topology
2AF7A 3AA1A 2OYOA 2IJCA 1KNCA 2JN8A 4AKRA 1VKEA 1ME5A 2Q0TA 2KXPA 2QEUA 3AAAA 3BEYA 3D7IA 2OUWA 3LK41 2PFXA 1P8CA 2O4DA 5DIKA 2CWQA 5ADXK 3LVYA 2ES9A 4G9QA 2PRRA 3AAEA 3AA0A 2KZ7A 3LK3A 3AA7A 1LW1A 3LK2A 3AA6A 2GMYA 5AFUK 3C1LA 1IZNA 1GU9A 5DIPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AF7 A;  2OYO A;  2IJC A;  1KNC A;  1VKE A;  1ME5 A;  2Q0T A;  2QEU A;  3D7I A;  3BEY A;  2OUW A;  2PFX A;  1P8C A;  2O4D A;  5DIK A;  2CWQ A;  3LVY A;  4G9Q A;  2PRR A;  1LW1 A;  2GMY A;  3C1L A;  1GU9 A;  5DIP A; 
#chains in the Genus database with same CATH topology
 2AF7 A;  3AA1 A;  2OYO A;  2IJC A;  1KNC A;  2JN8 A;  4AKR A;  1VKE A;  1ME5 A;  2Q0T A;  2KXP A;  2QEU A;  3AAA A;  3BEY A;  3D7I A;  2OUW A;  3LK4 1;  2PFX A;  1P8C A;  2O4D A;  5DIK A;  2CWQ A;  5ADX K;  3LVY A;  2ES9 A;  4G9Q A;  2PRR A;  3AAE A;  3AA0 A;  2KZ7 A;  3LK3 A;  3AA7 A;  1LW1 A;  3LK2 A;  3AA6 A;  2GMY A;  5AFU K;  3C1L A;  1IZN A;  1GU9 A;  5DIP A; 
#chains in the Genus database with same CATH homology
 2AF7 A;  3AA1 A;  2OYO A;  2IJC A;  1KNC A;  2JN8 A;  4AKR A;  1VKE A;  1ME5 A;  2Q0T A;  2KXP A;  2QEU A;  3AAA A;  3BEY A;  3D7I A;  2OUW A;  3LK4 1;  2PFX A;  1P8C A;  2O4D A;  5DIK A;  2CWQ A;  5ADX K;  3LVY A;  2ES9 A;  4G9Q A;  2PRR A;  3AAE A;  3AA0 A;  2KZ7 A;  3LK3 A;  3AA7 A;  1LW1 A;  3LK2 A;  3AA6 A;  2GMY A;  5AFU K;  3C1L A;  1IZN A;  1GU9 A;  5DIP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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