3AA1A

Crystal structure of actin capping protein in complex with the cp-binding motif derived from ckip-1
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
271
structure length
271
Chain Sequence
RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYDDQVLITEHGDLGNGRFLDPRNKISFKFDHLRKEASDPQPEDTESALKQWRDACDSALRAYVKDHYPNGFCTVYGKSIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVAAVLKIQVHYYEDGNVQLVSHKDIQDSVQVSSDVQTAKEFIKIIENAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Two distinct mechanisms for actin capping protein regulation--steric and allosteric inhibition
pubmed doi rcsb
source organism Gallus gallus
molecule tags Protein binding
molecule keywords F-actin-capping protein subunit alpha-1
total genus 83
structure length 271
sequence length 271
ec nomenclature
pdb deposition date 2009-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01267 F-actin_cap_A F-actin capping protein alpha subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 3aa1A01
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 3aa1A02
2KXPB 5AFUK 3AAEA 3LK42 3AA1B 3AAEB 5ADXK 3LK3B 2KZ7A 3LK3A 3AA0B 3AA0A 2KZ7B 3LK41 3AA7B 3LK2A 4AKRB 2KXPA 4AKRA 3AA6A 3AAAA 1IZNB 1IZNA 3AA7A 3LK2B 5AFUL 5ADXL 3AAAB 3AA6B 3AA1A
chains in the Genus database with same CATH superfamily
2KXPB 5AFUK 2XE5A 4XNLA 4FT6A 5GTIO 1ZHYA 2PFXA 2IWVA 2KC0A 4AYDC 1P8CA 4GCQA 4AKMA 1H6S1 3VZTX 5H2FO 1T16A 4RLBA 2Y2XA 4FZLA 3AAEB 3AA6B 2MNHA 3A0HO 3SZVA 3GP6A 4FSOA 4O3ZA 1BH3A 2PRRA 3LK3B 3QRAA 4RL9A 8PRNA 2AF7A 6PRNA 1ORMA 5DIKA 3POQA 3LK41 3PORA 5DL8A 4AKRB 4FUVA 3T20A 3KZIO 1ME5A 4G9QA 4AZLA 3HWBA 2M07A 3VY9X 4LSFA 2QEUA 4KRAA 4N74A 3VY8X 2ODJA 2WJRA 2ZFGA 3C5OA 2IJCA 3UPGA 4G76A 1IZNB 4U9CA 2KDYA 4FSPA 4D64A 5AFUL 3BS0A 1GFMA 2XE1A 3PGRA 3PGSA 4GHBA 1LW1A 3PRNA 2W81C 2PRNA 1HXTA 2F1CX 2QTKA 3RBHA 3SY9A 4AYID 2GE4A 4N58A 3PQUA 3JCUO 3TZGA 2CWQA 4AYMC 4AYNA 5D5DA 3VZWX 3D7IA 2Y0HA 3AA1B 3SYBA 1Q9GA 4RJWA 5G39A 4C4VA 3C1LA 2FGRA 2J1NA 5DIPA 3DWNA 4FRXA 3PF1A 3LK3A 4UB8O 4FQEA 2FGQX 2O4VA 4LSIA 4XNKA 5FVNA 3AA7B 3FYXA 4AUIA 2X27X 4LSHA 1ZHZA 4O3YA 2WVPA 4FMSA 2R4PA 3SZDA 2WJQA 4FZNA 2LFUA 1OPFA 2R4OA 4KR8A 1PHOA 3EMNX 3V8UA 3WI4A 3WU2O 4D5UA 4F4BA 5DL6A 3PQSA 3AA6A 4JCHA 3DWOX 2XG6A 3AAAA 3PGUA 4G75A 1GFOA 3UU2A 1IZNA 3AA7A 3HW9A 1MPFA 2Y0KA 3WI5A 5ADXL 2XE3A 4PR7A 3DZMA 3KVDD 1S5LO 4RLCA 5T5FA 4C00A 1P4TA 4JFBA 1VKEA 5G3AA 3HOEA 4C4VB 1YS5A 1GFNA 5B5EO 3K19A 1QJPA 4O49A 4N59A 5EE2A 2M06A 5KAFO 4KR4A 1THQA 2ZLDA 1BT9A 4PJ0O 5KAIO 4FOZA 5ADXK 2XTQA 3POXA 2KZ7A 3AA0B 2R89A 3JTYA 3O0EA 4GF4A 2GMYA 3BRYA 3A0BO 4N75A 1MM5A 1HXXA 1QJ8A 1QJ9A 5JDPA 1E54A 3T24A 3DA4A 4K3BA 3A2SX 5TISO 2Q0TA 1ZHXA 2KXPA 2XE2A 4GCPA 4QQ1A 3VZUX 4E1SA 1ZHWA 2YPVA 4K3CA 2F1TA 3T0SA 2N2MA 1GFPA 2K0LA 2N2LA 3BEYA 2ES9A 5E79O 2J4UP 1GU9A 1KNCA 5G26A 3AA1A 1OSMA 3NSGA 5B66O 2YNKA 2K4TA 3AAEA 3LK42 4O3WA 4RJXA 1BXWA 5GV0A 5GTHO 1ZHTA 2O4DA 2R4LA 3QRCA 2W80C 1HXUA 2R8AA 4UB6O 3BRZA 4CTDA 2OYOA 2OUWA 2IWWA 4D65A 4GCSA 3VE1A 3LVYA 2OMFA 3VE2A 3AA0A 2KZ7B 3POUA 4IL6O 4Z3TA 3LK2A 1GFQA 5DL5A 4FZMA 4B61A 2XTRA 2X9KA 1G90A 2JQYA 4O3XB 5IYUA 2AXTO 4LSEA 1T1LA 1PRNA 5DL7A 5G38A 2XMXA 2PORA 7PRNA 4AKRA 2Y0LA 4FESA 2MHLA 2Y7SA 4FRTA 2LHFA 5PRNA 4C69X 4E1TA 3SYSA 2JN8A 2JMMA 3HOLA 3G7GA 1Q9FA 3LK2B 2R4NA 3NJTA 4AYEC 4BUMX 3UAQA 4O4UA 4PUXA 3AAAB 3DA3A 2ERVA 1MM4A 2R88A 4AFKA 4O4XA 2F1VA 3SY7A
chains in the Genus database with same CATH topology
2KXPB 5AFUK 2XE5A 4XNLA 4FT6A 1ZHYA 2PFXA 2KC0A 4AYDC 1P8CA 4GCQA 4AKMA 1H6S1 3VZTX 4RLBA 2Y2XA 4FZLA 3AAEB 3AA6B 2MNHA 3SZVA 3GP6A 4FSOA 4O3ZA 1BH3A 2PRRA 3LK3B 3QRAA 4RL9A 8PRNA 2AF7A 6PRNA 1ORMA 5DIKA 3POQA 3LK41 3PORA 5DL8A 4AKRB 4FUVA 3T20A 1ME5A 4G9QA 4AZLA 3HWBA 2M07A 3VY9X 4LSFA 2QEUA 4KRAA 3VY8X 2ODJA 3C5OA 2ZFGA 2IJCA 3UPGA 4G76A 1IZNB 4U9CA 2KDYA 4FSPA 4D64A 5AFUL 1GFMA 2XE1A 4GHBA 1LW1A 3PRNA 2W81C 2PRNA 1HXTA 2QTKA 3RBHA 3SY9A 4AYID 2GE4A 4N58A 3PQUA 3TZGA 2CWQA 4AYMC 4AYNA 5D5DA 3VZWX 3D7IA 2Y0HA 3AA1B 3SYBA 1Q9GA 4RJWA 3C1LA 2FGRA 2J1NA 5DIPA 4FRXA 3LK3A 2FGQX 2O4VA 4LSIA 4XNKA 5FVNA 3AA7B 3FYXA 4AUIA 2X27X 4LSHA 1ZHZA 4O3YA 4FMSA 3SZDA 4KR8A 4FZNA 2LFUA 1OPFA 3WI4A 1PHOA 3EMNX 3V8UA 4D5UA 4F4BA 5DL6A 3PQSA 3AA6A 4JCHA 4G75A 2XG6A 3AAAA 3UU2A 1GFOA 1IZNA 3AA7A 3HW9A 1MPFA 2Y0KA 3WI5A 5ADXL 2XE3A 5T5FA 3KVDD 4RLCA 1P4TA 4JFBA 1VKEA 3HOEA 1YS5A 1GFNA 3K19A 1QJPA 4O49A 4N59A 5EE2A 2M06A 4KR4A 1THQA 2ZLDA 1BT9A 4FOZA 5ADXK 2XTQA 3POXA 2KZ7A 3AA0B 3JTYA 3O0EA 4GF4A 2GMYA 1MM5A 1HXXA 1QJ8A 1QJ9A 5JDPA 1E54A 3T24A 3DA4A 3A2SX 2Q0TA 1ZHXA 2KXPA 2XE2A 4GCPA 4QQ1A 3VZUX 4E1SA 1ZHWA 2YPVA 2F1TA 3T0SA 2N2MA 1GFPA 2K0LA 2N2LA 3BEYA 2ES9A 2J4UP 1GU9A 1KNCA 5G26A 3AA1A 1OSMA 3NSGA 2YNKA 2K4TA 3AAEA 3LK42 4O3WA 4RJXA 1BXWA 5GV0A 1ZHTA 2O4DA 3QRCA 2W80C 1HXUA 2OYOA 2OUWA 4D65A 4GCSA 3VE1A 3LVYA 2OMFA 3VE2A 3AA0A 2KZ7B 3POUA 4Z3TA 3LK2A 1GFQA 5DL5A 4FZMA 4B61A 2XTRA 1G90A 4O3XB 5IYUA 4LSEA 1PRNA 5DL7A 7PRNA 2XMXA 2PORA 4AKRA 2Y0LA 4FESA 2MHLA 2Y7SA 4FRTA 2LHFA 5PRNA 4C69X 4E1TA 3SYSA 2JN8A 2JMMA 3HOLA 3G7GA 1Q9FA 3LK2B 4AYEC 4BUMX 3UAQA 4O4UA 4PUXA 3AAAB 3DA3A 2ERVA 1MM4A 4AFKA 4O4XA 2F1VA 3SY7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KXP B;  5AFU K;  3AAE A;  3LK4 2;  3AA1 B;  3AAE B;  5ADX K;  3LK3 B;  2KZ7 A;  3LK3 A;  3AA0 B;  3AA0 A;  2KZ7 B;  3LK4 1;  3AA7 B;  3LK2 A;  4AKR B;  2KXP A;  4AKR A;  3AA6 A;  3AAA A;  1IZN B;  1IZN A;  3AA7 A;  3LK2 B;  5AFU L;  5ADX L;  3AAA B;  3AA6 B;  3AA1 A; 
#chains in the Genus database with same CATH topology
 2KXP B;  5AFU K;  2XE5 A;  4XNL A;  4FT6 A;  5GTI O;  1ZHY A;  2PFX A;  2IWV A;  2KC0 A;  4AYD C;  1P8C A;  4GCQ A;  4AKM A;  1H6S 1;  3VZT X;  5H2F O;  1T16 A;  4RLB A;  2Y2X A;  4FZL A;  3AAE B;  3AA6 B;  2MNH A;  3A0H O;  3SZV A;  3GP6 A;  4FSO A;  4O3Z A;  1BH3 A;  2PRR A;  3LK3 B;  3QRA A;  4RL9 A;  8PRN A;  2AF7 A;  6PRN A;  1ORM A;  5DIK A;  3POQ A;  3LK4 1;  3POR A;  5DL8 A;  4AKR B;  4FUV A;  3T20 A;  3KZI O;  1ME5 A;  4G9Q A;  4AZL A;  3HWB A;  2M07 A;  3VY9 X;  4LSF A;  2QEU A;  4KRA A;  4N74 A;  3VY8 X;  2ODJ A;  2WJR A;  2ZFG A;  3C5O A;  2IJC A;  3UPG A;  4G76 A;  1IZN B;  4U9C A;  2KDY A;  4FSP A;  4D64 A;  5AFU L;  3BS0 A;  1GFM A;  2XE1 A;  3PGR A;  3PGS A;  4GHB A;  1LW1 A;  3PRN A;  2W81 C;  2PRN A;  1HXT A;  2F1C X;  2QTK A;  3RBH A;  3SY9 A;  4AYI D;  2GE4 A;  4N58 A;  3PQU A;  3JCU O;  3TZG A;  2CWQ A;  4AYM C;  4AYN A;  5D5D A;  3VZW X;  3D7I A;  2Y0H A;  3AA1 B;  3SYB A;  1Q9G A;  4RJW A;  5G39 A;  4C4V A;  3C1L A;  2FGR A;  2J1N A;  5DIP A;  3DWN A;  4FRX A;  3PF1 A;  3LK3 A;  4UB8 O;  4FQE A;  2FGQ X;  2O4V A;  4LSI A;  4XNK A;  5FVN A;  3AA7 B;  3FYX A;  4AUI A;  2X27 X;  4LSH A;  1ZHZ A;  4O3Y A;  2WVP A;  4FMS A;  2R4P A;  3SZD A;  2WJQ A;  4FZN A;  2LFU A;  1OPF A;  2R4O A;  4KR8 A;  1PHO A;  3EMN X;  3V8U A;  3WI4 A;  3WU2 O;  4D5U A;  4F4B A;  5DL6 A;  3PQS A;  3AA6 A;  4JCH A;  3DWO X;  2XG6 A;  3AAA A;  3PGU A;  4G75 A;  1GFO A;  3UU2 A;  1IZN A;  3AA7 A;  3HW9 A;  1MPF A;  2Y0K A;  3WI5 A;  5ADX L;  2XE3 A;  4PR7 A;  3DZM A;  3KVD D;  1S5L O;  4RLC A;  5T5F A;  4C00 A;  1P4T A;  4JFB A;  1VKE A;  5G3A A;  3HOE A;  4C4V B;  1YS5 A;  1GFN A;  5B5E O;  3K19 A;  1QJP A;  4O49 A;  4N59 A;  5EE2 A;  2M06 A;  5KAF O;  4KR4 A;  1THQ A;  2ZLD A;  1BT9 A;  4PJ0 O;  5KAI O;  4FOZ A;  5ADX K;  2XTQ A;  3POX A;  2KZ7 A;  3AA0 B;  2R89 A;  3JTY A;  3O0E A;  4GF4 A;  2GMY A;  3BRY A;  3A0B O;  4N75 A;  1MM5 A;  1HXX A;  1QJ8 A;  1QJ9 A;  5JDP A;  1E54 A;  3T24 A;  3DA4 A;  4K3B A;  3A2S X;  5TIS O;  2Q0T A;  1ZHX A;  2KXP A;  2XE2 A;  4GCP A;  4QQ1 A;  3VZU X;  4E1S A;  1ZHW A;  2YPV A;  4K3C A;  2F1T A;  3T0S A;  2N2M A;  1GFP A;  2K0L A;  2N2L A;  3BEY A;  2ES9 A;  5E79 O;  2J4U P;  1GU9 A;  1KNC A;  5G26 A;  3AA1 A;  1OSM A;  3NSG A;  5B66 O;  2YNK A;  2K4T A;  3AAE A;  3LK4 2;  4O3W A;  4RJX A;  1BXW A;  5GV0 A;  5GTH O;  1ZHT A;  2O4D A;  2R4L A;  3QRC A;  2W80 C;  1HXU A;  2R8A A;  4UB6 O;  3BRZ A;  4CTD A;  2OYO A;  2OUW A;  2IWW A;  4D65 A;  4GCS A;  3VE1 A;  3LVY A;  2OMF A;  3VE2 A;  3AA0 A;  2KZ7 B;  3POU A;  4IL6 O;  4Z3T A;  3LK2 A;  1GFQ A;  5DL5 A;  4FZM A;  4B61 A;  2XTR A;  2X9K A;  1G90 A;  2JQY A;  4O3X B;  5IYU A;  2AXT O;  4LSE A;  1T1L A;  1PRN A;  5DL7 A;  5G38 A;  2XMX A;  2POR A;  7PRN A;  4AKR A;  2Y0L A;  4FES A;  2MHL A;  2Y7S A;  4FRT A;  2LHF A;  5PRN A;  4C69 X;  4E1T A;  3SYS A;  2JN8 A;  2JMM A;  3HOL A;  3G7G A;  1Q9F A;  3LK2 B;  2R4N A;  3NJT A;  4AYE C;  4BUM X;  3UAQ A;  4O4U A;  4PUX A;  3AAA B;  3DA3 A;  2ERV A;  1MM4 A;  2R88 A;  4AFK A;  4O4X A;  2F1V A;  3SY7 A; 
#chains in the Genus database with same CATH homology
 2KXP B;  5AFU K;  2XE5 A;  4XNL A;  4FT6 A;  1ZHY A;  2PFX A;  2KC0 A;  4AYD C;  1P8C A;  4GCQ A;  4AKM A;  1H6S 1;  3VZT X;  4RLB A;  2Y2X A;  4FZL A;  3AAE B;  3AA6 B;  2MNH A;  3SZV A;  3GP6 A;  4FSO A;  4O3Z A;  1BH3 A;  2PRR A;  3LK3 B;  3QRA A;  4RL9 A;  8PRN A;  2AF7 A;  6PRN A;  1ORM A;  5DIK A;  3POQ A;  3LK4 1;  3POR A;  5DL8 A;  4AKR B;  4FUV A;  3T20 A;  1ME5 A;  4G9Q A;  4AZL A;  3HWB A;  2M07 A;  3VY9 X;  4LSF A;  2QEU A;  4KRA A;  3VY8 X;  2ODJ A;  3C5O A;  2ZFG A;  2IJC A;  3UPG A;  4G76 A;  1IZN B;  4U9C A;  2KDY A;  4FSP A;  4D64 A;  5AFU L;  1GFM A;  2XE1 A;  4GHB A;  1LW1 A;  3PRN A;  2W81 C;  2PRN A;  1HXT A;  2QTK A;  3RBH A;  3SY9 A;  4AYI D;  2GE4 A;  4N58 A;  3PQU A;  3TZG A;  2CWQ A;  4AYM C;  4AYN A;  5D5D A;  3VZW X;  3D7I A;  2Y0H A;  3AA1 B;  3SYB A;  1Q9G A;  4RJW A;  3C1L A;  2FGR A;  2J1N A;  5DIP A;  4FRX A;  3LK3 A;  2FGQ X;  2O4V A;  4LSI A;  4XNK A;  5FVN A;  3AA7 B;  3FYX A;  4AUI A;  2X27 X;  4LSH A;  1ZHZ A;  4O3Y A;  4FMS A;  3SZD A;  4KR8 A;  4FZN A;  2LFU A;  1OPF A;  3WI4 A;  1PHO A;  3EMN X;  3V8U A;  4D5U A;  4F4B A;  5DL6 A;  3PQS A;  3AA6 A;  4JCH A;  4G75 A;  2XG6 A;  3AAA A;  3UU2 A;  1GFO A;  1IZN A;  3AA7 A;  3HW9 A;  1MPF A;  2Y0K A;  3WI5 A;  5ADX L;  2XE3 A;  5T5F A;  3KVD D;  4RLC A;  1P4T A;  4JFB A;  1VKE A;  3HOE A;  1YS5 A;  1GFN A;  3K19 A;  1QJP A;  4O49 A;  4N59 A;  5EE2 A;  2M06 A;  4KR4 A;  1THQ A;  2ZLD A;  1BT9 A;  4FOZ A;  5ADX K;  2XTQ A;  3POX A;  2KZ7 A;  3AA0 B;  3JTY A;  3O0E A;  4GF4 A;  2GMY A;  1MM5 A;  1HXX A;  1QJ8 A;  1QJ9 A;  5JDP A;  1E54 A;  3T24 A;  3DA4 A;  3A2S X;  2Q0T A;  1ZHX A;  2KXP A;  2XE2 A;  4GCP A;  4QQ1 A;  3VZU X;  4E1S A;  1ZHW A;  2YPV A;  2F1T A;  3T0S A;  2N2M A;  1GFP A;  2K0L A;  2N2L A;  3BEY A;  2ES9 A;  2J4U P;  1GU9 A;  1KNC A;  5G26 A;  3AA1 A;  1OSM A;  3NSG A;  2YNK A;  2K4T A;  3AAE A;  3LK4 2;  4O3W A;  4RJX A;  1BXW A;  5GV0 A;  1ZHT A;  2O4D A;  3QRC A;  2W80 C;  1HXU A;  2OYO A;  2OUW A;  4D65 A;  4GCS A;  3VE1 A;  3LVY A;  2OMF A;  3VE2 A;  3AA0 A;  2KZ7 B;  3POU A;  4Z3T A;  3LK2 A;  1GFQ A;  5DL5 A;  4FZM A;  4B61 A;  2XTR A;  1G90 A;  4O3X B;  5IYU A;  4LSE A;  1PRN A;  5DL7 A;  7PRN A;  2XMX A;  2POR A;  4AKR A;  2Y0L A;  4FES A;  2MHL A;  2Y7S A;  4FRT A;  2LHF A;  5PRN A;  4C69 X;  4E1T A;  3SYS A;  2JN8 A;  2JMM A;  3HOL A;  3G7G A;  1Q9F A;  3LK2 B;  4AYE C;  4BUM X;  3UAQ A;  4O4U A;  4PUX A;  3AAA B;  3DA3 A;  2ERV A;  1MM4 A;  4AFK A;  4O4X A;  2F1V A;  3SY7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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