3AAEA

Crystal structure of actin capping protein in complex with carmil fragment
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
270
structure length
270
Chain Sequence
RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYDDQVLITEHGDLGNGRFLDPRNKISFKFDHLRKEASDPQPEDTESALKQWRDACDSALRAYVKDHYPNGFCTVYGKSIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVAAVLKIQVHYYEDGNVQLVSHKDIQDSVQVSSDVQTAKEFIKIIENAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Two distinct mechanisms for the regulation of actin capping protein-competitive or allosteric inhibitions
rcsb
source organism Gallus gallus
molecule tags Protein binding
molecule keywords F-actin-capping protein subunit alpha-1
total genus 77
structure length 270
sequence length 270
chains with identical sequence C, E, G, I
ec nomenclature
pdb deposition date 2009-11-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01267 F-actin_cap_A F-actin capping protein alpha subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 3aaeA01
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 3aaeA02
3AA7A 3LK41 5ADXK 3AA7B 2KXPB 3AA1A 3AA1B 3LK2B 2KXPA 3AAEB 2KZ7A 3AA6B 3AA0B 1IZNA 3LK3A 5ADXL 5AFUK 3AAAA 3AAAB 3AAEA 3LK2A 3LK3B 5AFUL 3AA0A 1IZNB 3AA6A 2KZ7B 3LK42 4AKRA 4AKRB
chains in the Genus database with same CATH superfamily
5H2FO 2YNKA 2IJCA 2MHLA 3LK41 5FVNA 2AF7A 3NSGA 2O4DA 2WVPA 2XG6A 4O3WA 1YS5A 2FGQX 5PRNA 4PUXA 1HXUA 2PORA 4BUMX 2R4PA 3AA1A 4KRAA 4RL9A 4RLBA 5TISO 4FSOA 1BH3A 1MPFA 1HXXA 4K3CA 2KXPA 3AAEB 2Y0LA 2KZ7A 4GCQA 1HXTA 2IWVA 4U9CA 1PRNA 4GCPA 5ADXL 3UPGA 4FSPA 5G26A 1LW1A 2R4OA 4FT6A 4O3ZA 1GFOA 4UB8O 4FMSA 4AKMA 3K19A 3VZUX 1KNCA 3AAAB 2ODJA 2GMYA 4FRTA 3POXA 3HWBA 4D65A 4G75A 3C1LA 1OPFA 4LSIA 2ERVA 3DZMA 1OSMA 5GTHO 3LK3B 5AFUL 4JCHA 5GTIO 1IZNB 4AUIA 3KVDD 3LVYA 1H6S1 4QQ1A 1Q9FA 3UAQA 1QJPA 5DL8A 1THQA 3VY9X 3PGSA 3SY9A 4G9QA 2AXTO 5DL7A 4FZLA 4UB6O 4N58A 2X9KA 2XTRA 3HOEA 3KZIO 4JFBA 4AYNA 2N2MA 3FYXA 4C00A 1QJ9A 2O4VA 2J4UP 3PQSA 4K3BA 4Z3TA 3LK2B 1GFQA 3O0EA 2OYOA 4FQEA 1BT9A 4E1TA 3AA6B 3AA0B 4LSFA 1G90A 3GP6A 3VE2A 1GFPA 5E79O 5G38A 1PHOA 4RJWA 3PQUA 2J1NA 5D5DA 4C69X 2IWWA 4FOZA 1T16A 3WI4A 1GU9A 3DA3A 5EE2A 4F4BA 2KDYA 4LSEA 4KR4A 4O49A 3T24A 6PRNA 2Q0TA 4AYMC 2F1CX 3DWNA 4AYID 3RBHA 3SYBA 3AA0A 2KC0A 1QJ8A 2OUWA 2WJRA 4LSHA 4O4UA 4FUVA 4AKRA 2M07A 3NJTA 4GCSA 4AYEC 2FGRA 5B5EO 3HW9A 3AA7A 2OMFA 1ORMA 2JMMA 2LHFA 5ADXK 3A0HO 8PRNA 5IYUA 2PFXA 2F1VA 3WU2O 3AA1B 3DA4A 1MM5A 2Y7SA 3D7IA 3BRZA 4E1SA 3DWOX 4AYDC 2R89A 4C4VA 3A0BO 4GHBA 2JQYA 2K0LA 1P4TA 3PRNA 4FESA 4PR7A 2GE4A 2WJQA 4RJXA 4O3YA 5AFUK 2K4TA 4RLCA 1BXWA 2XE1A 2ZLDA 3WI5A 3QRAA 3SZVA 5JDPA 3AAAA 1T1LA 5G3AA 5KAIO 5T5FA 3JTYA 3EMNX 5G39A 5DL6A 3SYSA 1P8CA 2XMXA 3AAEA 2F1TA 3VY8X 3SZDA 5B66O 5GV0A 2R4LA 4AKRB 2ZFGA 1E54A 3POQA 1VKEA 2KZ7B 4B61A 3LK42 4N74A 3QRCA 3VE1A 3PF1A 3PGUA 4N59A 1ME5A 2R4NA 2CWQA 2ES9A 2XE2A 3BRYA 1GFNA 2W81C 1ZHYA 4KR8A 4FZNA 3TZGA 2M06A 2XE3A 3JCUO 3PORA 4FRXA 3PGRA 4XNKA 3AA7B 5KAFO 1ZHZA 2KXPB 1ZHTA 3VZWX 5DL5A 4CTDA 2YPVA 3A2SX 4G76A 2Y2XA 1GFMA 2R88A 2QEUA 2R8AA 4IL6O 4N75A 4C4VB 1IZNA 2JN8A 2QTKA 2Y0HA 4O3XB 4PJ0O 3LK3A 5DIKA 3POUA 2N2LA 3HOLA 3T0SA 4AZLA 7PRNA 1ZHXA 4FZMA 3G7GA 4D5UA 4AFKA 2XE5A 2PRNA 4D64A 2X27X 1ZHWA 4XNLA 3VZTX 1Q9GA 2LFUA 5DIPA 3BEYA 3LK2A 1MM4A 4GF4A 4O4XA 1S5LO 3UU2A 2MNHA 3AA6A 2Y0KA 3SY7A 3V8UA 3T20A 2PRRA 2XTQA 3BS0A 3C5OA 2W80C
chains in the Genus database with same CATH topology
2YNKA 2IJCA 2MHLA 3LK41 5FVNA 2AF7A 3NSGA 2O4DA 2XG6A 4O3WA 1YS5A 2FGQX 5PRNA 4PUXA 1HXUA 2PORA 5IYUA 4BUMX 3AA1A 4KRAA 4RL9A 4RLBA 4FSOA 1BH3A 1MPFA 1HXXA 2KXPA 3AAEB 2Y0LA 2KZ7A 4GCQA 1HXTA 3UPGA 4U9CA 1PRNA 4GCPA 5ADXL 4FSPA 5G26A 1LW1A 4FT6A 4O3ZA 1GFOA 4AKMA 4FMSA 3K19A 3VZUX 1KNCA 3AAAB 2ODJA 2GMYA 4FRTA 3POXA 3HWBA 4D65A 4G75A 3C1LA 1OPFA 4LSIA 2ERVA 1OSMA 3LK3B 5AFUL 4JCHA 1IZNB 4AUIA 3KVDD 3LVYA 1H6S1 4QQ1A 1Q9FA 3UAQA 1QJPA 5DL8A 1THQA 3VY9X 3SY9A 4G9QA 5DL7A 4FZLA 4N58A 2XTRA 4AYNA 3HOEA 4JFBA 2J4UP 2N2MA 3FYXA 1QJ9A 2O4VA 3PQSA 4Z3TA 3LK2B 1GFQA 3O0EA 2OYOA 1BT9A 4E1TA 3AA6B 3AA0B 4LSFA 1G90A 3GP6A 3VE2A 1GFPA 1PHOA 4RJWA 3PQUA 2J1NA 5D5DA 4C69X 4FOZA 3WI4A 1GU9A 3DA3A 5EE2A 4F4BA 2KDYA 4LSEA 4KR4A 4O49A 3T24A 6PRNA 2Q0TA 4AYMC 4AYID 3RBHA 3SYBA 3AA0A 2KC0A 1QJ8A 2OUWA 4LSHA 4O4UA 4FUVA 4AKRA 2M07A 4GCSA 4AYEC 2FGRA 3HW9A 3AA7A 2OMFA 1ORMA 2JMMA 2LHFA 5ADXK 8PRNA 2PFXA 2F1VA 3AA1B 3DA4A 1MM5A 2Y7SA 3D7IA 4E1SA 4AYDC 4GHBA 2K0LA 3PRNA 1P4TA 4FESA 4RJXA 2GE4A 4O3YA 5AFUK 2K4TA 4RLCA 1BXWA 2XE1A 2ZLDA 3WI5A 3QRAA 3SZVA 5JDPA 3AAAA 5T5FA 3SYSA 3JTYA 3EMNX 5DL6A 3VY8X 1P8CA 2XMXA 3AAEA 2F1TA 3SZDA 5GV0A 2ZFGA 1E54A 3POQA 1VKEA 2KZ7B 4B61A 3LK42 3QRCA 3VE1A 4N59A 1ME5A 2CWQA 2ES9A 2XE2A 4AKRB 1GFNA 2W81C 1ZHYA 4KR8A 4FZNA 3TZGA 2M06A 2XE3A 3PORA 4FRXA 4XNKA 3AA7B 1ZHZA 2KXPB 1ZHTA 3VZWX 5DL5A 2YPVA 3A2SX 4G76A 2Y2XA 1GFMA 2QEUA 1IZNA 2JN8A 2QTKA 2Y0HA 4O3XB 3T0SA 3LK3A 5DIKA 3POUA 2N2LA 3HOLA 4AZLA 7PRNA 1ZHXA 4FZMA 3G7GA 4D5UA 4AFKA 2XE5A 2PRNA 4D64A 2X27X 1ZHWA 4XNLA 3VZTX 1Q9GA 2LFUA 5DIPA 3BEYA 3LK2A 1MM4A 4GF4A 4O4XA 3UU2A 2MNHA 3AA6A 2Y0KA 3SY7A 3V8UA 3T20A 2PRRA 2XTQA 3C5OA 2W80C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AA7 A;  3LK4 1;  5ADX K;  3AA7 B;  2KXP B;  3AA1 A;  3AA1 B;  3LK2 B;  2KXP A;  3AAE B;  2KZ7 A;  3AA6 B;  3AA0 B;  1IZN A;  3LK3 A;  5ADX L;  5AFU K;  3AAA A;  3AAA B;  3AAE A;  3LK2 A;  3LK3 B;  5AFU L;  3AA0 A;  1IZN B;  3AA6 A;  2KZ7 B;  3LK4 2;  4AKR A;  4AKR B; 
#chains in the Genus database with same CATH topology
 5H2F O;  2YNK A;  2IJC A;  2MHL A;  3LK4 1;  5FVN A;  2AF7 A;  3NSG A;  2O4D A;  2WVP A;  2XG6 A;  4O3W A;  1YS5 A;  2FGQ X;  5PRN A;  4PUX A;  1HXU A;  2POR A;  4BUM X;  2R4P A;  3AA1 A;  4KRA A;  4RL9 A;  4RLB A;  5TIS O;  4FSO A;  1BH3 A;  1MPF A;  1HXX A;  4K3C A;  2KXP A;  3AAE B;  2Y0L A;  2KZ7 A;  4GCQ A;  1HXT A;  2IWV A;  4U9C A;  1PRN A;  4GCP A;  5ADX L;  3UPG A;  4FSP A;  5G26 A;  1LW1 A;  2R4O A;  4FT6 A;  4O3Z A;  1GFO A;  4UB8 O;  4FMS A;  4AKM A;  3K19 A;  3VZU X;  1KNC A;  3AAA B;  2ODJ A;  2GMY A;  4FRT A;  3POX A;  3HWB A;  4D65 A;  4G75 A;  3C1L A;  1OPF A;  4LSI A;  2ERV A;  3DZM A;  1OSM A;  5GTH O;  3LK3 B;  5AFU L;  4JCH A;  5GTI O;  1IZN B;  4AUI A;  3KVD D;  3LVY A;  1H6S 1;  4QQ1 A;  1Q9F A;  3UAQ A;  1QJP A;  5DL8 A;  1THQ A;  3VY9 X;  3PGS A;  3SY9 A;  4G9Q A;  2AXT O;  5DL7 A;  4FZL A;  4UB6 O;  4N58 A;  2X9K A;  2XTR A;  3HOE A;  3KZI O;  4JFB A;  4AYN A;  2N2M A;  3FYX A;  4C00 A;  1QJ9 A;  2O4V A;  2J4U P;  3PQS A;  4K3B A;  4Z3T A;  3LK2 B;  1GFQ A;  3O0E A;  2OYO A;  4FQE A;  1BT9 A;  4E1T A;  3AA6 B;  3AA0 B;  4LSF A;  1G90 A;  3GP6 A;  3VE2 A;  1GFP A;  5E79 O;  5G38 A;  1PHO A;  4RJW A;  3PQU A;  2J1N A;  5D5D A;  4C69 X;  2IWW A;  4FOZ A;  1T16 A;  3WI4 A;  1GU9 A;  3DA3 A;  5EE2 A;  4F4B A;  2KDY A;  4LSE A;  4KR4 A;  4O49 A;  3T24 A;  6PRN A;  2Q0T A;  4AYM C;  2F1C X;  3DWN A;  4AYI D;  3RBH A;  3SYB A;  3AA0 A;  2KC0 A;  1QJ8 A;  2OUW A;  2WJR A;  4LSH A;  4O4U A;  4FUV A;  4AKR A;  2M07 A;  3NJT A;  4GCS A;  4AYE C;  2FGR A;  5B5E O;  3HW9 A;  3AA7 A;  2OMF A;  1ORM A;  2JMM A;  2LHF A;  5ADX K;  3A0H O;  8PRN A;  5IYU A;  2PFX A;  2F1V A;  3WU2 O;  3AA1 B;  3DA4 A;  1MM5 A;  2Y7S A;  3D7I A;  3BRZ A;  4E1S A;  3DWO X;  4AYD C;  2R89 A;  4C4V A;  3A0B O;  4GHB A;  2JQY A;  2K0L A;  1P4T A;  3PRN A;  4FES A;  4PR7 A;  2GE4 A;  2WJQ A;  4RJX A;  4O3Y A;  5AFU K;  2K4T A;  4RLC A;  1BXW A;  2XE1 A;  2ZLD A;  3WI5 A;  3QRA A;  3SZV A;  5JDP A;  3AAA A;  1T1L A;  5G3A A;  5KAI O;  5T5F A;  3JTY A;  3EMN X;  5G39 A;  5DL6 A;  3SYS A;  1P8C A;  2XMX A;  3AAE A;  2F1T A;  3VY8 X;  3SZD A;  5B66 O;  5GV0 A;  2R4L A;  4AKR B;  2ZFG A;  1E54 A;  3POQ A;  1VKE A;  2KZ7 B;  4B61 A;  3LK4 2;  4N74 A;  3QRC A;  3VE1 A;  3PF1 A;  3PGU A;  4N59 A;  1ME5 A;  2R4N A;  2CWQ A;  2ES9 A;  2XE2 A;  3BRY A;  1GFN A;  2W81 C;  1ZHY A;  4KR8 A;  4FZN A;  3TZG A;  2M06 A;  2XE3 A;  3JCU O;  3POR A;  4FRX A;  3PGR A;  4XNK A;  3AA7 B;  5KAF O;  1ZHZ A;  2KXP B;  1ZHT A;  3VZW X;  5DL5 A;  4CTD A;  2YPV A;  3A2S X;  4G76 A;  2Y2X A;  1GFM A;  2R88 A;  2QEU A;  2R8A A;  4IL6 O;  4N75 A;  4C4V B;  1IZN A;  2JN8 A;  2QTK A;  2Y0H A;  4O3X B;  4PJ0 O;  3LK3 A;  5DIK A;  3POU A;  2N2L A;  3HOL A;  3T0S A;  4AZL A;  7PRN A;  1ZHX A;  4FZM A;  3G7G A;  4D5U A;  4AFK A;  2XE5 A;  2PRN A;  4D64 A;  2X27 X;  1ZHW A;  4XNL A;  3VZT X;  1Q9G A;  2LFU A;  5DIP A;  3BEY A;  3LK2 A;  1MM4 A;  4GF4 A;  4O4X A;  1S5L O;  3UU2 A;  2MNH A;  3AA6 A;  2Y0K A;  3SY7 A;  3V8U A;  3T20 A;  2PRR A;  2XTQ A;  3BS0 A;  3C5O A;  2W80 C; 
#chains in the Genus database with same CATH homology
 2YNK A;  2IJC A;  2MHL A;  3LK4 1;  5FVN A;  2AF7 A;  3NSG A;  2O4D A;  2XG6 A;  4O3W A;  1YS5 A;  2FGQ X;  5PRN A;  4PUX A;  1HXU A;  2POR A;  5IYU A;  4BUM X;  3AA1 A;  4KRA A;  4RL9 A;  4RLB A;  4FSO A;  1BH3 A;  1MPF A;  1HXX A;  2KXP A;  3AAE B;  2Y0L A;  2KZ7 A;  4GCQ A;  1HXT A;  3UPG A;  4U9C A;  1PRN A;  4GCP A;  5ADX L;  4FSP A;  5G26 A;  1LW1 A;  4FT6 A;  4O3Z A;  1GFO A;  4AKM A;  4FMS A;  3K19 A;  3VZU X;  1KNC A;  3AAA B;  2ODJ A;  2GMY A;  4FRT A;  3POX A;  3HWB A;  4D65 A;  4G75 A;  3C1L A;  1OPF A;  4LSI A;  2ERV A;  1OSM A;  3LK3 B;  5AFU L;  4JCH A;  1IZN B;  4AUI A;  3KVD D;  3LVY A;  1H6S 1;  4QQ1 A;  1Q9F A;  3UAQ A;  1QJP A;  5DL8 A;  1THQ A;  3VY9 X;  3SY9 A;  4G9Q A;  5DL7 A;  4FZL A;  4N58 A;  2XTR A;  4AYN A;  3HOE A;  4JFB A;  2J4U P;  2N2M A;  3FYX A;  1QJ9 A;  2O4V A;  3PQS A;  4Z3T A;  3LK2 B;  1GFQ A;  3O0E A;  2OYO A;  1BT9 A;  4E1T A;  3AA6 B;  3AA0 B;  4LSF A;  1G90 A;  3GP6 A;  3VE2 A;  1GFP A;  1PHO A;  4RJW A;  3PQU A;  2J1N A;  5D5D A;  4C69 X;  4FOZ A;  3WI4 A;  1GU9 A;  3DA3 A;  5EE2 A;  4F4B A;  2KDY A;  4LSE A;  4KR4 A;  4O49 A;  3T24 A;  6PRN A;  2Q0T A;  4AYM C;  4AYI D;  3RBH A;  3SYB A;  3AA0 A;  2KC0 A;  1QJ8 A;  2OUW A;  4LSH A;  4O4U A;  4FUV A;  4AKR A;  2M07 A;  4GCS A;  4AYE C;  2FGR A;  3HW9 A;  3AA7 A;  2OMF A;  1ORM A;  2JMM A;  2LHF A;  5ADX K;  8PRN A;  2PFX A;  2F1V A;  3AA1 B;  3DA4 A;  1MM5 A;  2Y7S A;  3D7I A;  4E1S A;  4AYD C;  4GHB A;  2K0L A;  3PRN A;  1P4T A;  4FES A;  4RJX A;  2GE4 A;  4O3Y A;  5AFU K;  2K4T A;  4RLC A;  1BXW A;  2XE1 A;  2ZLD A;  3WI5 A;  3QRA A;  3SZV A;  5JDP A;  3AAA A;  5T5F A;  3SYS A;  3JTY A;  3EMN X;  5DL6 A;  3VY8 X;  1P8C A;  2XMX A;  3AAE A;  2F1T A;  3SZD A;  5GV0 A;  2ZFG A;  1E54 A;  3POQ A;  1VKE A;  2KZ7 B;  4B61 A;  3LK4 2;  3QRC A;  3VE1 A;  4N59 A;  1ME5 A;  2CWQ A;  2ES9 A;  2XE2 A;  4AKR B;  1GFN A;  2W81 C;  1ZHY A;  4KR8 A;  4FZN A;  3TZG A;  2M06 A;  2XE3 A;  3POR A;  4FRX A;  4XNK A;  3AA7 B;  1ZHZ A;  2KXP B;  1ZHT A;  3VZW X;  5DL5 A;  2YPV A;  3A2S X;  4G76 A;  2Y2X A;  1GFM A;  2QEU A;  1IZN A;  2JN8 A;  2QTK A;  2Y0H A;  4O3X B;  3T0S A;  3LK3 A;  5DIK A;  3POU A;  2N2L A;  3HOL A;  4AZL A;  7PRN A;  1ZHX A;  4FZM A;  3G7G A;  4D5U A;  4AFK A;  2XE5 A;  2PRN A;  4D64 A;  2X27 X;  1ZHW A;  4XNL A;  3VZT X;  1Q9G A;  2LFU A;  5DIP A;  3BEY A;  3LK2 A;  1MM4 A;  4GF4 A;  4O4X A;  3UU2 A;  2MNH A;  3AA6 A;  2Y0K A;  3SY7 A;  3V8U A;  3T20 A;  2PRR A;  2XTQ A;  3C5O A;  2W80 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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