5AFUK

Cryo-em structure of dynein tail-dynactin-bicd2n complex
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
275
structure length
275
Chain Sequence
RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYEDQVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPEEVDGSLKSWRESCDSALRAYVKDHYSNGFCTVYAKNIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSVTVSNEAQTAKEFIKIIEHAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structure of the Dynactin Complex and its Interaction with Dynein.
pubmed doi rcsb
molecule tags Motor protein
molecule keywords DYNEIN TAIL
total genus 65
structure length 275
sequence length 275
ec nomenclature
pdb deposition date 2015-01-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 5afuK01
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 5afuK02
3LK3B 3AA7A 5AFUK 3AA6B 3LK3A 3AA1A 3AAEA 1IZNA 1IZNB 3AAEB 3AAAB 3AAAA 3LK42 5ADXL 3LK2A 3AA0B 3AA0A 3LK2B 2KZ7A 5ADXK 2KXPA 2KXPB 3LK41 2KZ7B 3AA7B 3AA6A 4AKRA 5AFUL 4AKRB 3AA1B
chains in the Genus database with same CATH superfamily
3WI5A 1QJPA 3A2SX 3AA6B 3GP6A 4O3XB 4N59A 4CTDA 1GFQA 3AA1A 5DL6A 1IZNA 3O0EA 3AAAB 2WJRA 4N74A 4O3ZA 2GE4A 4PJ0O 5PRNA 3UAQA 2Y2XA 5T5FA 4XNLA 3FYXA 1HXXA 2M07A 1VKEA 3PF1A 4LSEA 4AKMA 1T1LA 3LK2A 4UB6O 5H2FO 4D64A 2ZFGA 4XNKA 2PRRA 2PRNA 2ODJA 4RJWA 3SY7A 5ADXK 3WU2O 5G39A 1HXUA 3QRAA 1P4TA 3BS0A 1ORMA 2IWVA 2JN8A 3POUA 2ZLDA 2XTRA 5JDPA 5AFUL 2ERVA 4RL9A 2LFUA 2OYOA 4KR4A 3HOEA 3POQA 5E79O 2J1NA 5KAIO 3WI4A 4C4VA 4G76A 1QJ8A 3DWNA 3V8UA 4E1SA 2W81C 2ES9A 2MNHA 1PRNA 2Y0LA 3PQSA 3JTYA 4PUXA 1ZHWA 3K19A 4KR8A 3SZVA 5IYUA 4GHBA 5AFUK 1G90A 3T24A 1T16A 1MM5A 3AAEA 1ZHTA 3LK42 3PRNA 4K3BA 5B5EO 5G3AA 4FSPA 2XE5A 4GCQA 5G38A 4FOZA 2YNKA 2R89A 4F4BA 3UU2A 2WVPA 2AF7A 3D7IA 3HOLA 5GTIO 3BRYA 4RJXA 1ZHXA 3LK2B 4AYNA 4O49A 2F1VA 5GTHO 4C00A 1BT9A 4FZLA 2KXPA 2R4LA 2R88A 4C69X 1KNCA 1MPFA 1THQA 2XE3A 3QRCA 4AYEC 5GV0A 3AA6A 1GFPA 2R8AA 2XE1A 3BEYA 2QEUA 1QJ9A 2W80C 3JCUO 1GFOA 3PGSA 1ZHYA 2F1CX 4O3YA 3KZIO 2X9KA 3EMNX 4LSHA 2O4DA 3RBHA 4AYDC 3A0BO 4K3CA 4B61A 3KVDD 3VY9X 3DZMA 1PHOA 3LK3B 3AA7A 5D5DA 5EE2A 3TZGA 3POXA 2MHLA 4AYID 2J4UP 2K4TA 2F1TA 1BXWA 3BRZA 2M06A 3A0HO 2PFXA 3DA4A 4FSOA 1IZNB 4KRAA 1Q9GA 4FUVA 4LSIA 3SZDA 3UPGA 2KDYA 4FRTA 1HXTA 2R4NA 2GMYA 4GCPA 4FT6A 4RLBA 1LW1A 3C1LA 3DA3A 2R4OA 2XMXA 3AA0B 2OUWA 1ZHZA 4FRXA 4O4XA 4O3WA 5DL7A 2N2LA 6PRNA 3PGUA 1H6S1 4E1TA 2JMMA 4N58A 1GU9A 3LVYA 7PRNA 4RLCA 3SY9A 4FZMA 3PORA 4FZNA 3VZTX 4AKRA 3T0SA 3SYSA 3VY8X 5DL8A 3VZUX 4AKRB 4FQEA 3T20A 3AA1B 2IJCA 3NSGA 4JCHA 5DL5A 4C4VB 1MM4A 2KC0A 2YPVA 1E54A 3HW9A 5B66O 2X27X 4G75A 2CWQA 1GFMA 2OMFA 3PQUA 4QQ1A 5FVNA 4BUMX 2FGRA 4PR7A 5G26A 1Q9FA 5DIPA 1OPFA 4AUIA 3LK3A 2JQYA 5KAFO 1OSMA 2N2MA 4JFBA 3NJTA 3DWOX 3AAEB 2PORA 3VE1A 4AZLA 3AAAA 3C5OA 3VE2A 2Q0TA 2Y7SA 4GF4A 5DIKA 4GCSA 4IL6O 4D65A 8PRNA 5ADXL 2IWWA 2O4VA 4U9CA 2QTKA 1P8CA 4UB8O 1ME5A 2Y0KA 4FESA 3PGRA 3AA0A 3SYBA 2KZ7A 2AXTO 4O4UA 5TISO 2KXPB 2XTQA 1S5LO 3LK41 2KZ7B 3G7GA 2FGQX 4G9QA 4LSFA 3VZWX 4AFKA 3AA7B 2XE2A 4Z3TA 2XG6A 4N75A 4FMSA 2LHFA 2K0LA 1BH3A 2Y0HA 3HWBA 1GFNA 1YS5A 2R4PA 4AYMC 2WJQA 4D5UA
chains in the Genus database with same CATH topology
3WI5A 1QJPA 3A2SX 3AA6B 3GP6A 4O3XB 4N59A 1GFQA 3AA1A 5DL6A 1IZNA 3O0EA 3AAAB 4O3ZA 5PRNA 3UAQA 2GE4A 2Y2XA 5T5FA 4XNLA 3FYXA 1HXXA 2M07A 1VKEA 4LSEA 4AKMA 3LK2A 4D64A 2ZFGA 4XNKA 2PRRA 2PRNA 2ODJA 4RJWA 3SY7A 5ADXK 1HXUA 3QRAA 1P4TA 1ORMA 2JN8A 3POUA 2ZLDA 2XTRA 5JDPA 5AFUL 2ERVA 4RL9A 2LFUA 2OYOA 4KR4A 3HOEA 3POQA 3WI4A 2J1NA 4G76A 1QJ8A 3V8UA 4E1SA 2W81C 2ES9A 2MNHA 1PRNA 2Y0LA 3PQSA 3JTYA 4PUXA 1ZHWA 3K19A 4KR8A 3SZVA 4GHBA 5AFUK 1G90A 3T24A 1MM5A 3AAEA 1ZHTA 3LK42 3PRNA 4FSPA 2XE5A 4GCQA 4FOZA 2YNKA 4F4BA 3UU2A 3HOLA 2AF7A 3D7IA 4RJXA 1ZHXA 3LK2B 4AYNA 4O49A 2F1VA 1BT9A 4FZLA 2KXPA 4C69X 1KNCA 1MPFA 1THQA 2XE3A 3QRCA 4AYEC 5GV0A 3AA6A 1GFPA 2XE1A 3BEYA 2QEUA 1QJ9A 2W80C 1GFOA 3VZUX 1ZHYA 4O3YA 4AYDC 4LSHA 3EMNX 3RBHA 2O4DA 4B61A 3KVDD 3VY9X 1PHOA 3LK3B 3AA7A 5D5DA 3TZGA 3POXA 2MHLA 4AYID 2J4UP 2K4TA 2F1TA 1BXWA 4FSOA 2M06A 4KRAA 2PFXA 3DA4A 4LSIA 1IZNB 5EE2A 1Q9GA 4FUVA 3SZDA 3UPGA 2KDYA 4FRTA 1HXTA 2GMYA 4GCPA 4FT6A 4RLBA 1LW1A 3C1LA 3DA3A 2XMXA 3AA0B 4FRXA 2OUWA 1ZHZA 4O3WA 4O4XA 5DL7A 6PRNA 2N2LA 1H6S1 4E1TA 2JMMA 4N58A 1GU9A 3LVYA 7PRNA 4RLCA 3SY9A 4FZMA 3PORA 4FZNA 3VZTX 4AKRA 3T0SA 3SYSA 3VY8X 5DL8A 3T20A 4AKRB 3AA1B 2IJCA 3NSGA 4JCHA 5DL5A 1MM4A 2KC0A 2YPVA 1E54A 3HW9A 2X27X 4G75A 2CWQA 1GFMA 2OMFA 3PQUA 4QQ1A 5FVNA 4BUMX 2FGRA 5G26A 1Q9FA 5DIPA 1OPFA 4AUIA 3LK3A 3VE1A 1OSMA 2N2MA 4JFBA 3AAEB 2PORA 4AZLA 3AAAA 3C5OA 3VE2A 2Q0TA 2Y7SA 4GF4A 5DIKA 4GCSA 4D65A 8PRNA 5ADXL 2O4VA 4U9CA 2QTKA 1P8CA 1ME5A 2Y0KA 4FESA 3AA0A 3SYBA 2KZ7A 4O4UA 2KXPB 2XTQA 5IYUA 3LK41 2KZ7B 3G7GA 2FGQX 4G9QA 4LSFA 3VZWX 4AFKA 3AA7B 2XE2A 4Z3TA 2XG6A 4FMSA 2LHFA 2K0LA 1BH3A 2Y0HA 3HWBA 1GFNA 1YS5A 4AYMC 4D5UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LK3 B;  3AA7 A;  5AFU K;  3AA6 B;  3LK3 A;  3AA1 A;  3AAE A;  1IZN A;  1IZN B;  3AAE B;  3AAA B;  3AAA A;  3LK4 2;  5ADX L;  3LK2 A;  3AA0 B;  3AA0 A;  3LK2 B;  2KZ7 A;  5ADX K;  2KXP A;  2KXP B;  3LK4 1;  2KZ7 B;  3AA7 B;  3AA6 A;  4AKR A;  5AFU L;  4AKR B;  3AA1 B; 
#chains in the Genus database with same CATH topology
 3WI5 A;  1QJP A;  3A2S X;  3AA6 B;  3GP6 A;  4O3X B;  4N59 A;  4CTD A;  1GFQ A;  3AA1 A;  5DL6 A;  1IZN A;  3O0E A;  3AAA B;  2WJR A;  4N74 A;  4O3Z A;  2GE4 A;  4PJ0 O;  5PRN A;  3UAQ A;  2Y2X A;  5T5F A;  4XNL A;  3FYX A;  1HXX A;  2M07 A;  1VKE A;  3PF1 A;  4LSE A;  4AKM A;  1T1L A;  3LK2 A;  4UB6 O;  5H2F O;  4D64 A;  2ZFG A;  4XNK A;  2PRR A;  2PRN A;  2ODJ A;  4RJW A;  3SY7 A;  5ADX K;  3WU2 O;  5G39 A;  1HXU A;  3QRA A;  1P4T A;  3BS0 A;  1ORM A;  2IWV A;  2JN8 A;  3POU A;  2ZLD A;  2XTR A;  5JDP A;  5AFU L;  2ERV A;  4RL9 A;  2LFU A;  2OYO A;  4KR4 A;  3HOE A;  3POQ A;  5E79 O;  2J1N A;  5KAI O;  3WI4 A;  4C4V A;  4G76 A;  1QJ8 A;  3DWN A;  3V8U A;  4E1S A;  2W81 C;  2ES9 A;  2MNH A;  1PRN A;  2Y0L A;  3PQS A;  3JTY A;  4PUX A;  1ZHW A;  3K19 A;  4KR8 A;  3SZV A;  5IYU A;  4GHB A;  5AFU K;  1G90 A;  3T24 A;  1T16 A;  1MM5 A;  3AAE A;  1ZHT A;  3LK4 2;  3PRN A;  4K3B A;  5B5E O;  5G3A A;  4FSP A;  2XE5 A;  4GCQ A;  5G38 A;  4FOZ A;  2YNK A;  2R89 A;  4F4B A;  3UU2 A;  2WVP A;  2AF7 A;  3D7I A;  3HOL A;  5GTI O;  3BRY A;  4RJX A;  1ZHX A;  3LK2 B;  4AYN A;  4O49 A;  2F1V A;  5GTH O;  4C00 A;  1BT9 A;  4FZL A;  2KXP A;  2R4L A;  2R88 A;  4C69 X;  1KNC A;  1MPF A;  1THQ A;  2XE3 A;  3QRC A;  4AYE C;  5GV0 A;  3AA6 A;  1GFP A;  2R8A A;  2XE1 A;  3BEY A;  2QEU A;  1QJ9 A;  2W80 C;  3JCU O;  1GFO A;  3PGS A;  1ZHY A;  2F1C X;  4O3Y A;  3KZI O;  2X9K A;  3EMN X;  4LSH A;  2O4D A;  3RBH A;  4AYD C;  3A0B O;  4K3C A;  4B61 A;  3KVD D;  3VY9 X;  3DZM A;  1PHO A;  3LK3 B;  3AA7 A;  5D5D A;  5EE2 A;  3TZG A;  3POX A;  2MHL A;  4AYI D;  2J4U P;  2K4T A;  2F1T A;  1BXW A;  3BRZ A;  2M06 A;  3A0H O;  2PFX A;  3DA4 A;  4FSO A;  1IZN B;  4KRA A;  1Q9G A;  4FUV A;  4LSI A;  3SZD A;  3UPG A;  2KDY A;  4FRT A;  1HXT A;  2R4N A;  2GMY A;  4GCP A;  4FT6 A;  4RLB A;  1LW1 A;  3C1L A;  3DA3 A;  2R4O A;  2XMX A;  3AA0 B;  2OUW A;  1ZHZ A;  4FRX A;  4O4X A;  4O3W A;  5DL7 A;  2N2L A;  6PRN A;  3PGU A;  1H6S 1;  4E1T A;  2JMM A;  4N58 A;  1GU9 A;  3LVY A;  7PRN A;  4RLC A;  3SY9 A;  4FZM A;  3POR A;  4FZN A;  3VZT X;  4AKR A;  3T0S A;  3SYS A;  3VY8 X;  5DL8 A;  3VZU X;  4AKR B;  4FQE A;  3T20 A;  3AA1 B;  2IJC A;  3NSG A;  4JCH A;  5DL5 A;  4C4V B;  1MM4 A;  2KC0 A;  2YPV A;  1E54 A;  3HW9 A;  5B66 O;  2X27 X;  4G75 A;  2CWQ A;  1GFM A;  2OMF A;  3PQU A;  4QQ1 A;  5FVN A;  4BUM X;  2FGR A;  4PR7 A;  5G26 A;  1Q9F A;  5DIP A;  1OPF A;  4AUI A;  3LK3 A;  2JQY A;  5KAF O;  1OSM A;  2N2M A;  4JFB A;  3NJT A;  3DWO X;  3AAE B;  2POR A;  3VE1 A;  4AZL A;  3AAA A;  3C5O A;  3VE2 A;  2Q0T A;  2Y7S A;  4GF4 A;  5DIK A;  4GCS A;  4IL6 O;  4D65 A;  8PRN A;  5ADX L;  2IWW A;  2O4V A;  4U9C A;  2QTK A;  1P8C A;  4UB8 O;  1ME5 A;  2Y0K A;  4FES A;  3PGR A;  3AA0 A;  3SYB A;  2KZ7 A;  2AXT O;  4O4U A;  5TIS O;  2KXP B;  2XTQ A;  1S5L O;  3LK4 1;  2KZ7 B;  3G7G A;  2FGQ X;  4G9Q A;  4LSF A;  3VZW X;  4AFK A;  3AA7 B;  2XE2 A;  4Z3T A;  2XG6 A;  4N75 A;  4FMS A;  2LHF A;  2K0L A;  1BH3 A;  2Y0H A;  3HWB A;  1GFN A;  1YS5 A;  2R4P A;  4AYM C;  2WJQ A;  4D5U A; 
#chains in the Genus database with same CATH homology
 3WI5 A;  1QJP A;  3A2S X;  3AA6 B;  3GP6 A;  4O3X B;  4N59 A;  1GFQ A;  3AA1 A;  5DL6 A;  1IZN A;  3O0E A;  3AAA B;  4O3Z A;  5PRN A;  3UAQ A;  2GE4 A;  2Y2X A;  5T5F A;  4XNL A;  3FYX A;  1HXX A;  2M07 A;  1VKE A;  4LSE A;  4AKM A;  3LK2 A;  4D64 A;  2ZFG A;  4XNK A;  2PRR A;  2PRN A;  2ODJ A;  4RJW A;  3SY7 A;  5ADX K;  1HXU A;  3QRA A;  1P4T A;  1ORM A;  2JN8 A;  3POU A;  2ZLD A;  2XTR A;  5JDP A;  5AFU L;  2ERV A;  4RL9 A;  2LFU A;  2OYO A;  4KR4 A;  3HOE A;  3POQ A;  3WI4 A;  2J1N A;  4G76 A;  1QJ8 A;  3V8U A;  4E1S A;  2W81 C;  2ES9 A;  2MNH A;  1PRN A;  2Y0L A;  3PQS A;  3JTY A;  4PUX A;  1ZHW A;  3K19 A;  4KR8 A;  3SZV A;  4GHB A;  5AFU K;  1G90 A;  3T24 A;  1MM5 A;  3AAE A;  1ZHT A;  3LK4 2;  3PRN A;  4FSP A;  2XE5 A;  4GCQ A;  4FOZ A;  2YNK A;  4F4B A;  3UU2 A;  3HOL A;  2AF7 A;  3D7I A;  4RJX A;  1ZHX A;  3LK2 B;  4AYN A;  4O49 A;  2F1V A;  1BT9 A;  4FZL A;  2KXP A;  4C69 X;  1KNC A;  1MPF A;  1THQ A;  2XE3 A;  3QRC A;  4AYE C;  5GV0 A;  3AA6 A;  1GFP A;  2XE1 A;  3BEY A;  2QEU A;  1QJ9 A;  2W80 C;  1GFO A;  3VZU X;  1ZHY A;  4O3Y A;  4AYD C;  4LSH A;  3EMN X;  3RBH A;  2O4D A;  4B61 A;  3KVD D;  3VY9 X;  1PHO A;  3LK3 B;  3AA7 A;  5D5D A;  3TZG A;  3POX A;  2MHL A;  4AYI D;  2J4U P;  2K4T A;  2F1T A;  1BXW A;  4FSO A;  2M06 A;  4KRA A;  2PFX A;  3DA4 A;  4LSI A;  1IZN B;  5EE2 A;  1Q9G A;  4FUV A;  3SZD A;  3UPG A;  2KDY A;  4FRT A;  1HXT A;  2GMY A;  4GCP A;  4FT6 A;  4RLB A;  1LW1 A;  3C1L A;  3DA3 A;  2XMX A;  3AA0 B;  4FRX A;  2OUW A;  1ZHZ A;  4O3W A;  4O4X A;  5DL7 A;  6PRN A;  2N2L A;  1H6S 1;  4E1T A;  2JMM A;  4N58 A;  1GU9 A;  3LVY A;  7PRN A;  4RLC A;  3SY9 A;  4FZM A;  3POR A;  4FZN A;  3VZT X;  4AKR A;  3T0S A;  3SYS A;  3VY8 X;  5DL8 A;  3T20 A;  4AKR B;  3AA1 B;  2IJC A;  3NSG A;  4JCH A;  5DL5 A;  1MM4 A;  2KC0 A;  2YPV A;  1E54 A;  3HW9 A;  2X27 X;  4G75 A;  2CWQ A;  1GFM A;  2OMF A;  3PQU A;  4QQ1 A;  5FVN A;  4BUM X;  2FGR A;  5G26 A;  1Q9F A;  5DIP A;  1OPF A;  4AUI A;  3LK3 A;  3VE1 A;  1OSM A;  2N2M A;  4JFB A;  3AAE B;  2POR A;  4AZL A;  3AAA A;  3C5O A;  3VE2 A;  2Q0T A;  2Y7S A;  4GF4 A;  5DIK A;  4GCS A;  4D65 A;  8PRN A;  5ADX L;  2O4V A;  4U9C A;  2QTK A;  1P8C A;  1ME5 A;  2Y0K A;  4FES A;  3AA0 A;  3SYB A;  2KZ7 A;  4O4U A;  2KXP B;  2XTQ A;  5IYU A;  3LK4 1;  2KZ7 B;  3G7G A;  2FGQ X;  4G9Q A;  4LSF A;  3VZW X;  4AFK A;  3AA7 B;  2XE2 A;  4Z3T A;  2XG6 A;  4FMS A;  2LHF A;  2K0L A;  1BH3 A;  2Y0H A;  3HWB A;  1GFN A;  1YS5 A;  4AYM C;  4D5U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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