5AFUK

Cryo-em structure of dynein tail-dynactin-bicd2n complex
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
275
structure length
275
Chain Sequence
RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYEDQVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPEEVDGSLKSWRESCDSALRAYVKDHYSNGFCTVYAKNIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSVTVSNEAQTAKEFIKIIEHAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords DYNEIN TAIL
publication title The Structure of the Dynactin Complex and its Interaction with Dynein.
pubmed doi rcsb
molecule tags Motor protein
total genus 65
structure length 275
sequence length 275
ec nomenclature
pdb deposition date 2015-01-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 5afuK01
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 5afuK02
5AFUK 2KZ7B 5ADXL 2KXPB 3LK3A 3AA7A 3LK3B 3AAAA 3AA7B 3AA6A 4AKRA 5ADXK 3AAAB 1IZNA 3AA0A 3AA1A 3AA6B 4AKRB 1IZNB 3AAEA 3LK41 3AA1B 3AA0B 3LK42 5AFUL 3LK2A 3AAEB 3LK2B 2KZ7A 2KXPA
chains in the Genus database with same CATH superfamily
5DL5A 4K3BA 2KZ7B 5ADXL 2QEUA 3AA7A 2MNHA 5PRNA 4LSFA 3AAAB 3DA3A 3JTYA 4AKRB 2X9KA 4G9QA 4GCQA 3PF1A 4C4VB 3PGSA 3PGRA 4AYMC 3G7GA 2XE2A 3VY8X 4O3YA 2LFUA 1HXTA 1ZHYA 1MPFA 5GTHO 4FQEA 4AUIA 1LW1A 4AYEC 2WVPA 3VZTX 3DZMA 5T5FA 4N75A 2ZLDA 3LK2A 3TZGA 3SYSA 2Y7SA 3SY7A 1ZHWA 4AYID 4KR8A 1H6S1 5ADXK 6PRNA 2PRNA 3AA1A 4FOZA 3PQSA 4KRAA 5FVNA 3SZDA 4O4XA 2KZ7A 3LVYA 3VZWX 2ZFGA 3BS0A 1ZHXA 1GFOA 1GFMA 4D5UA 3LK3B 1Q9GA 3AAAA 4LSHA 2PORA 4AKRA 2CWQA 3VZUX 2N2MA 2Q0TA 4O49A 3PGUA 1IZNB 3JCUO 2XTQA 3UU2A 4D64A 4IL6O 3LK42 4C4VA 4E1SA 4AZLA 1PHOA 4G76A 5G38A 4UB8O 2OYOA 5DIPA 4BUMX 2FGRA 2LHFA 5E79O 2KDYA 3UAQA 2MHLA 4U9CA 1MM4A 5GTIO 1QJ9A 2J1NA 2IWVA 4JFBA 2QTKA 3WI4A 4PUXA 3AA6B 2K4TA 2O4VA 1T1LA 2Y0KA 4FT6A 4LSEA 1ZHTA 4E1TA 1VKEA 3HOEA 2J4UP 2KXPB 3LK3A 3POQA 3DWNA 4N74A 1E54A 2F1CX 2WJQA 1GFNA 4CTDA 4GF4A 1IZNA 4AYNA 3NSGA 2Y0LA 3QRAA 4KR4A 5JDPA 3PQUA 4FRTA 5DL7A 2M06A 2O4DA 5DL6A 2R4LA 1ORMA 4UB6O 1T16A 2ES9A 3WI5A 3AA0B 3BRYA 3VE1A 3K19A 2YNKA 4O3XB 2X27X 3NJTA 2PFXA 3QRCA 4K3CA 3C1LA 4FESA 1QJPA 1THQA 3T0SA 1QJ8A 4FZMA 5DL8A 4FSPA 1Q9FA 2XMXA 4N59A 3AA6A 3A2SX 2Y2XA 4G75A 5D5DA 5H2FO 2R4OA 4D65A 2KXPA 5G39A 4GCSA 4AKMA 2JN8A 1P4TA 4FRXA 7PRNA 5KAIO 5B66O 4O3WA 3BEYA 4N58A 4FSOA 1BT9A 1HXUA 5AFUL 2R88A 4O3ZA 2R4NA 4F4BA 1HXXA 2ERVA 2W81C 4JCHA 5KAFO 4C00A 4B61A 1P8CA 3A0BO 3PORA 4FZNA 3UPGA 3AA0A 3C5OA 2JMMA 4AFKA 2XE1A 4GCPA 4RJXA 5EE2A 4PJ0O 3HWBA 3VE2A 2ODJA 4RJWA 3DA4A 2IWWA 4RLCA 2GE4A 2OMFA 1YS5A 5IYUA 2K0LA 2XG6A 4RLBA 1OPFA 3BRZA 2AXTO 5AFUK 1KNCA 1MM5A 4O4UA 3KZIO 3RBHA 4FUVA 2GMYA 5G3AA 3DWOX 3T20A 2XTRA 4RL9A 3EMNX 3SZVA 3V8UA 2F1TA 3AAEB 2WJRA 3D7IA 3KVDD 2FGQX 2IJCA 1OSMA 3HOLA 3VY9X 3HW9A 2N2LA 2R8AA 2PRRA 2Y0HA 3GP6A 3POUA 3AA7B 1BH3A 1BXWA 2AF7A 3LK41 1GU9A 3SY9A 3WU2O 1ZHZA 4FZLA 2F1VA 2KC0A 2W80C 3PRNA 5G26A 1GFQA 3POXA 2YPVA 4C69X 2XE3A 4AYDC 1GFPA 1ME5A 2R89A 1PRNA 3A0HO 3O0EA 3LK2B 4XNKA 3SYBA 3T24A 4PR7A 3FYXA 4GHBA 4QQ1A 5GV0A 1S5LO 1G90A 2XE5A 2M07A 4XNLA 4Z3TA 8PRNA 4LSIA 3AAEA 5B5EO 3AA1B 2OUWA 2JQYA 2R4PA 5DIKA 4FMSA 5TISO
chains in the Genus database with same CATH topology
5DL5A 5AFUK 2KZ7B 3C1LA 4AZLA 2QEUA 5ADXL 1KNCA 1MM5A 1PHOA 1QJPA 4FESA 1THQA 3AA7A 1QJ8A 4G76A 2MNHA 4O4UA 5PRNA 3T0SA 4FZMA 5DL8A 4FSPA 3RBHA 4FUVA 2GMYA 1Q9FA 4LSFA 2XMXA 3T20A 4N59A 3AA6A 3AAAB 3DA3A 3JTYA 3A2SX 2OYOA 5DIPA 2XTRA 4AKRB 4RL9A 4BUMX 2FGRA 3EMNX 2LHFA 4G9QA 3SZVA 3V8UA 2F1TA 4GCQA 2KDYA 2Y2XA 4G75A 3AAEB 3UAQA 2MHLA 5D5DA 3D7IA 3KVDD 2FGQX 4D65A 2IJCA 2KXPA 4AYMC 1OSMA 3HOLA 4U9CA 3VY9X 1MM4A 3G7GA 3HW9A 4GCSA 2N2LA 2XE2A 3VY8X 4AKMA 2JN8A 2PRRA 4O3YA 1P4TA 1QJ9A 2LFUA 2J1NA 2Y0HA 3GP6A 1HXTA 1ZHYA 4FRXA 7PRNA 1MPFA 3POUA 3AA7B 1BH3A 4JFBA 2QTKA 3WI4A 4AUIA 4O3WA 1LW1A 4AYEC 3BEYA 1BXWA 4PUXA 3AA6B 4N58A 3VZTX 2AF7A 2K4TA 3LK41 4FSOA 2O4VA 1GU9A 1BT9A 5T5FA 2Y0KA 4FT6A 4LSEA 1ZHTA 1HXUA 3LK2A 2ZLDA 3SY9A 5AFUL 3TZGA 1ZHZA 4FZLA 2F1VA 4E1TA 1VKEA 2KC0A 3SYSA 3HOEA 4O3ZA 2W80C 4F4BA 1HXXA 2ERVA 2Y7SA 3PRNA 2J4UP 2KXPB 3LK3A 2W81C 5G26A 3SY7A 1GFQA 3POXA 1ZHWA 4JCHA 3POQA 4AYID 4KR8A 2YPVA 4C69X 2XE3A 4B61A 1E54A 1P8CA 1H6S1 3PORA 4FZNA 4AYDC 5ADXK 1GFNA 6PRNA 4GF4A 1IZNA 3AA0A 2PRNA 3AA1A 3C5OA 4AYNA 3UPGA 3NSGA 2Y0LA 1GFPA 3QRAA 1ME5A 4KR4A 2JMMA 5JDPA 3PQUA 4FRTA 4FOZA 5DL7A 2M06A 3PQSA 4KRAA 5FVNA 4AFKA 1PRNA 2O4DA 2XE1A 3SZDA 4O4XA 5DL6A 3O0EA 4GCPA 4RJXA 3LK2B 2KZ7A 3LVYA 1ORMA 4XNKA 3SYBA 3T24A 3VZWX 2ZFGA 5EE2A 3HWBA 3FYXA 4GHBA 1ZHXA 3VE2A 2ODJA 1GFOA 4QQ1A 1GFMA 4D5UA 3LK3B 1Q9GA 3AAAA 5GV0A 1G90A 4RJWA 2XE5A 2ES9A 4LSHA 2M07A 2PORA 4XNLA 4AKRA 3DA4A 4Z3TA 2CWQA 4RLCA 3VZUX 8PRNA 2N2MA 2GE4A 2OMFA 2Q0TA 1YS5A 4O49A 3WI5A 5IYUA 4LSIA 1IZNB 3AAEA 3AA0B 3AA1B 2XTQA 3UU2A 3VE1A 4D64A 2K0LA 3LK42 3K19A 2OUWA 2XG6A 4RLBA 2YNKA 4O3XB 2X27X 1OPFA 2PFXA 3QRCA 5DIKA 4FMSA 4E1SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5AFU K;  2KZ7 B;  5ADX L;  2KXP B;  3LK3 A;  3AA7 A;  3LK3 B;  3AAA A;  3AA7 B;  3AA6 A;  4AKR A;  5ADX K;  3AAA B;  1IZN A;  3AA0 A;  3AA1 A;  3AA6 B;  4AKR B;  1IZN B;  3AAE A;  3LK4 1;  3AA1 B;  3AA0 B;  3LK4 2;  5AFU L;  3LK2 A;  3AAE B;  3LK2 B;  2KZ7 A;  2KXP A; 
#chains in the Genus database with same CATH topology
 5DL5 A;  4K3B A;  2KZ7 B;  5ADX L;  2QEU A;  3AA7 A;  2MNH A;  5PRN A;  4LSF A;  3AAA B;  3DA3 A;  3JTY A;  4AKR B;  2X9K A;  4G9Q A;  4GCQ A;  3PF1 A;  4C4V B;  3PGS A;  3PGR A;  4AYM C;  3G7G A;  2XE2 A;  3VY8 X;  4O3Y A;  2LFU A;  1HXT A;  1ZHY A;  1MPF A;  5GTH O;  4FQE A;  4AUI A;  1LW1 A;  4AYE C;  2WVP A;  3VZT X;  3DZM A;  5T5F A;  4N75 A;  2ZLD A;  3LK2 A;  3TZG A;  3SYS A;  2Y7S A;  3SY7 A;  1ZHW A;  4AYI D;  4KR8 A;  1H6S 1;  5ADX K;  6PRN A;  2PRN A;  3AA1 A;  4FOZ A;  3PQS A;  4KRA A;  5FVN A;  3SZD A;  4O4X A;  2KZ7 A;  3LVY A;  3VZW X;  2ZFG A;  3BS0 A;  1ZHX A;  1GFO A;  1GFM A;  4D5U A;  3LK3 B;  1Q9G A;  3AAA A;  4LSH A;  2POR A;  4AKR A;  2CWQ A;  3VZU X;  2N2M A;  2Q0T A;  4O49 A;  3PGU A;  1IZN B;  3JCU O;  2XTQ A;  3UU2 A;  4D64 A;  4IL6 O;  3LK4 2;  4C4V A;  4E1S A;  4AZL A;  1PHO A;  4G76 A;  5G38 A;  4UB8 O;  2OYO A;  5DIP A;  4BUM X;  2FGR A;  2LHF A;  5E79 O;  2KDY A;  3UAQ A;  2MHL A;  4U9C A;  1MM4 A;  5GTI O;  1QJ9 A;  2J1N A;  2IWV A;  4JFB A;  2QTK A;  3WI4 A;  4PUX A;  3AA6 B;  2K4T A;  2O4V A;  1T1L A;  2Y0K A;  4FT6 A;  4LSE A;  1ZHT A;  4E1T A;  1VKE A;  3HOE A;  2J4U P;  2KXP B;  3LK3 A;  3POQ A;  3DWN A;  4N74 A;  1E54 A;  2F1C X;  2WJQ A;  1GFN A;  4CTD A;  4GF4 A;  1IZN A;  4AYN A;  3NSG A;  2Y0L A;  3QRA A;  4KR4 A;  5JDP A;  3PQU A;  4FRT A;  5DL7 A;  2M06 A;  2O4D A;  5DL6 A;  2R4L A;  1ORM A;  4UB6 O;  1T16 A;  2ES9 A;  3WI5 A;  3AA0 B;  3BRY A;  3VE1 A;  3K19 A;  2YNK A;  4O3X B;  2X27 X;  3NJT A;  2PFX A;  3QRC A;  4K3C A;  3C1L A;  4FES A;  1QJP A;  1THQ A;  3T0S A;  1QJ8 A;  4FZM A;  5DL8 A;  4FSP A;  1Q9F A;  2XMX A;  4N59 A;  3AA6 A;  3A2S X;  2Y2X A;  4G75 A;  5D5D A;  5H2F O;  2R4O A;  4D65 A;  2KXP A;  5G39 A;  4GCS A;  4AKM A;  2JN8 A;  1P4T A;  4FRX A;  7PRN A;  5KAI O;  5B66 O;  4O3W A;  3BEY A;  4N58 A;  4FSO A;  1BT9 A;  1HXU A;  5AFU L;  2R88 A;  4O3Z A;  2R4N A;  4F4B A;  1HXX A;  2ERV A;  2W81 C;  4JCH A;  5KAF O;  4C00 A;  4B61 A;  1P8C A;  3A0B O;  3POR A;  4FZN A;  3UPG A;  3AA0 A;  3C5O A;  2JMM A;  4AFK A;  2XE1 A;  4GCP A;  4RJX A;  5EE2 A;  4PJ0 O;  3HWB A;  3VE2 A;  2ODJ A;  4RJW A;  3DA4 A;  2IWW A;  4RLC A;  2GE4 A;  2OMF A;  1YS5 A;  5IYU A;  2K0L A;  2XG6 A;  4RLB A;  1OPF A;  3BRZ A;  2AXT O;  5AFU K;  1KNC A;  1MM5 A;  4O4U A;  3KZI O;  3RBH A;  4FUV A;  2GMY A;  5G3A A;  3DWO X;  3T20 A;  2XTR A;  4RL9 A;  3EMN X;  3SZV A;  3V8U A;  2F1T A;  3AAE B;  2WJR A;  3D7I A;  3KVD D;  2FGQ X;  2IJC A;  1OSM A;  3HOL A;  3VY9 X;  3HW9 A;  2N2L A;  2R8A A;  2PRR A;  2Y0H A;  3GP6 A;  3POU A;  3AA7 B;  1BH3 A;  1BXW A;  2AF7 A;  3LK4 1;  1GU9 A;  3SY9 A;  3WU2 O;  1ZHZ A;  4FZL A;  2F1V A;  2KC0 A;  2W80 C;  3PRN A;  5G26 A;  1GFQ A;  3POX A;  2YPV A;  4C69 X;  2XE3 A;  4AYD C;  1GFP A;  1ME5 A;  2R89 A;  1PRN A;  3A0H O;  3O0E A;  3LK2 B;  4XNK A;  3SYB A;  3T24 A;  4PR7 A;  3FYX A;  4GHB A;  4QQ1 A;  5GV0 A;  1S5L O;  1G90 A;  2XE5 A;  2M07 A;  4XNL A;  4Z3T A;  8PRN A;  4LSI A;  3AAE A;  5B5E O;  3AA1 B;  2OUW A;  2JQY A;  2R4P A;  5DIK A;  4FMS A;  5TIS O; 
#chains in the Genus database with same CATH homology
 5DL5 A;  5AFU K;  2KZ7 B;  3C1L A;  4AZL A;  2QEU A;  5ADX L;  1KNC A;  1MM5 A;  1PHO A;  1QJP A;  4FES A;  1THQ A;  3AA7 A;  1QJ8 A;  4G76 A;  2MNH A;  4O4U A;  5PRN A;  3T0S A;  4FZM A;  5DL8 A;  4FSP A;  3RBH A;  4FUV A;  2GMY A;  1Q9F A;  4LSF A;  2XMX A;  3T20 A;  4N59 A;  3AA6 A;  3AAA B;  3DA3 A;  3JTY A;  3A2S X;  2OYO A;  5DIP A;  2XTR A;  4AKR B;  4RL9 A;  4BUM X;  2FGR A;  3EMN X;  2LHF A;  4G9Q A;  3SZV A;  3V8U A;  2F1T A;  4GCQ A;  2KDY A;  2Y2X A;  4G75 A;  3AAE B;  3UAQ A;  2MHL A;  5D5D A;  3D7I A;  3KVD D;  2FGQ X;  4D65 A;  2IJC A;  2KXP A;  4AYM C;  1OSM A;  3HOL A;  4U9C A;  3VY9 X;  1MM4 A;  3G7G A;  3HW9 A;  4GCS A;  2N2L A;  2XE2 A;  3VY8 X;  4AKM A;  2JN8 A;  2PRR A;  4O3Y A;  1P4T A;  1QJ9 A;  2LFU A;  2J1N A;  2Y0H A;  3GP6 A;  1HXT A;  1ZHY A;  4FRX A;  7PRN A;  1MPF A;  3POU A;  3AA7 B;  1BH3 A;  4JFB A;  2QTK A;  3WI4 A;  4AUI A;  4O3W A;  1LW1 A;  4AYE C;  3BEY A;  1BXW A;  4PUX A;  3AA6 B;  4N58 A;  3VZT X;  2AF7 A;  2K4T A;  3LK4 1;  4FSO A;  2O4V A;  1GU9 A;  1BT9 A;  5T5F A;  2Y0K A;  4FT6 A;  4LSE A;  1ZHT A;  1HXU A;  3LK2 A;  2ZLD A;  3SY9 A;  5AFU L;  3TZG A;  1ZHZ A;  4FZL A;  2F1V A;  4E1T A;  1VKE A;  2KC0 A;  3SYS A;  3HOE A;  4O3Z A;  2W80 C;  4F4B A;  1HXX A;  2ERV A;  2Y7S A;  3PRN A;  2J4U P;  2KXP B;  3LK3 A;  2W81 C;  5G26 A;  3SY7 A;  1GFQ A;  3POX A;  1ZHW A;  4JCH A;  3POQ A;  4AYI D;  4KR8 A;  2YPV A;  4C69 X;  2XE3 A;  4B61 A;  1E54 A;  1P8C A;  1H6S 1;  3POR A;  4FZN A;  4AYD C;  5ADX K;  1GFN A;  6PRN A;  4GF4 A;  1IZN A;  3AA0 A;  2PRN A;  3AA1 A;  3C5O A;  4AYN A;  3UPG A;  3NSG A;  2Y0L A;  1GFP A;  3QRA A;  1ME5 A;  4KR4 A;  2JMM A;  5JDP A;  3PQU A;  4FRT A;  4FOZ A;  5DL7 A;  2M06 A;  3PQS A;  4KRA A;  5FVN A;  4AFK A;  1PRN A;  2O4D A;  2XE1 A;  3SZD A;  4O4X A;  5DL6 A;  3O0E A;  4GCP A;  4RJX A;  3LK2 B;  2KZ7 A;  3LVY A;  1ORM A;  4XNK A;  3SYB A;  3T24 A;  3VZW X;  2ZFG A;  5EE2 A;  3HWB A;  3FYX A;  4GHB A;  1ZHX A;  3VE2 A;  2ODJ A;  1GFO A;  4QQ1 A;  1GFM A;  4D5U A;  3LK3 B;  1Q9G A;  3AAA A;  5GV0 A;  1G90 A;  4RJW A;  2XE5 A;  2ES9 A;  4LSH A;  2M07 A;  2POR A;  4XNL A;  4AKR A;  3DA4 A;  4Z3T A;  2CWQ A;  4RLC A;  3VZU X;  8PRN A;  2N2M A;  2GE4 A;  2OMF A;  2Q0T A;  1YS5 A;  4O49 A;  3WI5 A;  5IYU A;  4LSI A;  1IZN B;  3AAE A;  3AA0 B;  3AA1 B;  2XTQ A;  3UU2 A;  3VE1 A;  4D64 A;  2K0L A;  3LK4 2;  3K19 A;  2OUW A;  2XG6 A;  4RLB A;  2YNK A;  4O3X B;  2X27 X;  1OPF A;  2PFX A;  3QRC A;  5DIK A;  4FMS A;  4E1S A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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