5AFUK

Cryo-em structure of dynein tail-dynactin-bicd2n complex
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
275
structure length
275
Chain Sequence
RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYEDQVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPEEVDGSLKSWRESCDSALRAYVKDHYSNGFCTVYAKNIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSVTVSNEAQTAKEFIKIIEHAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Motor protein
molecule keywords DYNEIN TAIL
publication title The Structure of the Dynactin Complex and its Interaction with Dynein.
pubmed doi rcsb
total genus 65
structure length 275
sequence length 275
ec nomenclature
pdb deposition date 2015-01-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 5afuK01
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 5afuK02
3AA7A 3AA7B 5AFUL 3AA6A 3LK41 5AFUK 3LK2A 3AA6B 3LK2B 2KZ7A 3LK3B 4AKRA 3AAAA 3LK3A 2KXPA 2KZ7B 4AKRB 3AAAB 2KXPB 1IZNB 1IZNA 5ADXL 3AA1A 5ADXK 3AA1B 3AA0A 3AA0B 3AAEB 3AAEA 3LK42
chains in the Genus database with same CATH superfamily
4PR7A 4O4UA 2MNHA 2Y7SA 4D5UA 4CTDA 2WVPA 5PRNA 3HW9A 3VE1A 4O49A 1P8CA 5JDPA 4AYNA 3AA0B 1GU9A 3NSGA 4N59A 4XNKA 3AAEA 4JCHA 1MPFA 3BEYA 3NJTA 3A0HO 2ES9A 3UAQA 2JMMA 4AFKA 3DA3A 3POQA 5AFUL 5AFUK 2ZLDA 2XMXA 2IJCA 3LK3B 6PRNA 3SYBA 3VZTX 1GFPA 2W80C 2YPVA 2IWVA 8PRNA 2GE4A 3LK42 3SZVA 3HWBA 3A0BO 3AA6A 4N74A 1T16A 2IWWA 4AKRA 1Q9FA 1IZNA 2WJQA 3T0SA 1LW1A 4K3BA 2AF7A 4D65A 3AAEB 1YS5A 4FQEA 1OSMA 3KVDD 4K3CA 2WJRA 4U9CA 3AAAB 1T1LA 3DZMA 3AA1A 4G9QA 1MM4A 2OYOA 2GMYA 2KDYA 3KZIO 1PHOA 3POUA 4N75A 3FYXA 5D5DA 1ZHWA 4IL6O 1HXUA 3HOEA 2K0LA 1OPFA 3PQUA 4FZMA 1BH3A 1S5LO 1IZNB 4FZNA 1GFOA 1QJ9A 2MHLA 1QJPA 1THQA 4LSHA 4RJXA 4O4XA 5GV0A 4FESA 3EMNX 3VZWX 4PJ0O 1QJ8A 2X27X 1Q9GA 3UU2A 4LSEA 1H6S1 5DIPA 4D64A 4UB8O 2KC0A 4LSFA 1ORMA 5GTIO 2PFXA 4KR8A 5B5EO 4C4VA 3DWNA 2OUWA 4FRXA 2AXTO 3LK2A 3SY9A 2KZ7A 4AUIA 4Z3TA 4FOZA 4AYEC 4FRTA 4F4BA 1VKEA 1PRNA 4G76A 3WI5A 4C69X 4GF4A 4G75A 2J1NA 3BS0A 5DIKA 5KAFO 4RLCA 2Y0LA 5T5FA 4XNLA 1GFMA 4KR4A 2XG6A 3SY7A 2ZFGA 1ME5A 3G7GA 4C00A 4GHBA 3D7IA 2F1TA 5FVNA 5IYUA 2J4UP 2XE3A 2KXPA 2F1VA 3K19A 3QRAA 1P4TA 2LFUA 3A2SX 5G39A 3O0EA 3WI4A 4FMSA 4E1SA 5DL5A 4C4VB 3AA7A 3RBHA 5DL7A 3LK2B 3BRYA 2R89A 4AZLA 4RLBA 4O3WA 3VY8X 4FT6A 4N58A 2QEUA 2Q0TA 3PF1A 2PORA 2XE2A 4UB6O 2FGRA 3WU2O 3AA6B 2N2LA 4AKRB 1GFNA 5DL8A 4O3ZA 4LSIA 2XE1A 2XE5A 2QTKA 3HOLA 5G38A 3AA0A 2JN8A 3SYSA 3QRCA 4FSOA 3VY9X 4FZLA 5TISO 1BXWA 2K4TA 4E1TA 3BRZA 3LVYA 3GP6A 3PRNA 4GCSA 3PGSA 1E54A 2FGQX 1G90A 1ZHTA 3AA1B 4O3YA 2R4OA 2XTRA 2R8AA 3PGRA 1ZHZA 3DA4A 2Y2XA 3T24A 2OMFA 5KAIO 2CWQA 3POXA 4PUXA 3C5OA 2O4DA 4QQ1A 1HXTA 2PRNA 4AYDC 5H2FO 2XTQA 1ZHXA 3AAAA 4FUVA 4RJWA 5ADXL 3PQSA 5ADXK 5EE2A 5G3AA 3JCUO 4AKMA 3SZDA 5G26A 1GFQA 3VE2A 4B61A 2YNKA 7PRNA 2M06A 1HXXA 3T20A 2KZ7B 4GCPA 2M07A 2N2MA 2R4LA 2F1CX 3TZGA 3PGUA 4AYID 1ZHYA 2R4NA 2W81C 3V8UA 3UPGA 2R88A 4FSPA 5GTHO 1BT9A 3VZUX 4KRAA 4RL9A 3C1LA 2LHFA 2KXPB 2JQYA 3PORA 1MM5A 5E79O 5B66O 2R4PA 2O4VA 2X9KA 2PRRA 4AYMC 3JTYA 3AA7B 2Y0HA 4BUMX 3LK41 3DWOX 4O3XB 3LK3A 4JFBA 2ERVA 1KNCA 2Y0KA 4GCQA 5DL6A 2ODJA
chains in the Genus database with same CATH topology
3POUA 3FYXA 5D5DA 4O4UA 3AA7A 1ZHWA 2MNHA 2Y7SA 4D5UA 1HXUA 3HOEA 3RBHA 5DL7A 2XTQA 1ZHXA 2K0LA 3LK2B 3AAAA 1OPFA 3PQUA 4FZMA 1BH3A 4O3WA 4RLBA 4AZLA 1IZNB 3VY8X 4FUVA 4FZNA 4FT6A 5PRNA 4RJWA 1GFOA 3HW9A 5ADXL 3PQSA 1QJ9A 4N58A 5ADXK 2MHLA 5EE2A 3VE1A 1QJPA 2QEUA 4O49A 1THQA 4LSHA 4RJXA 4O4XA 1P8CA 5JDPA 2Q0TA 4AKMA 4AYNA 3AA0B 1GU9A 2PORA 2XE2A 3NSGA 3AAEA 4N59A 4JCHA 2FGRA 4XNKA 3SZDA 1MPFA 5GV0A 3BEYA 4FESA 3EMNX 3VZWX 5G26A 2ES9A 3UAQA 1GFQA 2JMMA 1QJ8A 3VE2A 2X27X 4B61A 2YNKA 4AFKA 7PRNA 1Q9GA 3DA3A 3POQA 3UU2A 2M06A 4LSEA 5AFUL 1H6S1 5AFUK 2ZLDA 1HXXA 2XMXA 3AA6B 4AYEC 3T20A 2IJCA 3LK3B 6PRNA 2KZ7B 2N2LA 5DIPA 4AKRB 1GFNA 4GCPA 3SYBA 2M07A 5DL8A 4D64A 4O3ZA 2KC0A 2N2MA 3VZTX 1GFPA 4LSIA 2XE1A 4LSFA 1ORMA 2W80C 2XE5A 2YPVA 3TZGA 2QTKA 4AYID 3HOLA 1ZHYA 3AA0A 2JN8A 3SYSA 2PFXA 8PRNA 2GE4A 3LK42 4KR8A 2W81C 3QRCA 4FSOA 3V8UA 3VY9X 4FZLA 3SZVA 3UPGA 4FSPA 1BT9A 3HWBA 1BXWA 2K4TA 3VZUX 4E1TA 2OUWA 3AA6A 4FRXA 4KRAA 3LK2A 3SY9A 4RL9A 2KZ7A 4AUIA 4Z3TA 4FOZA 4AKRA 3C1LA 3LVYA 1Q9FA 2LHFA 3GP6A 2KXPB 3PRNA 4FRTA 3PORA 4GCSA 1VKEA 1IZNA 1MM5A 1PRNA 4G76A 4GF4A 1E54A 2FGQX 2J1NA 4G75A 3WI5A 1ZHTA 4C69X 3T0SA 1G90A 3AA1B 5DIKA 4O3YA 4RLCA 2Y0LA 5T5FA 4XNLA 1GFMA 1LW1A 4KR4A 2O4VA 2AF7A 2XG6A 3SY7A 4D65A 2XTRA 2ZFGA 3AAEB 1ME5A 2PRRA 3G7GA 1YS5A 4GHBA 4AYMC 1ZHZA 3JTYA 3D7IA 1OSMA 3AA7B 2Y0HA 3DA4A 2F1TA 3KVDD 5FVNA 5IYUA 2Y2XA 4BUMX 2J4UP 3T24A 3LK41 2XE3A 2OMFA 4U9CA 4O3XB 3LK3A 2KXPA 3AAAB 2F1VA 4JFBA 2CWQA 3K19A 3QRAA 1P4TA 2LFUA 2ERVA 1KNCA 3POXA 3AA1A 4PUXA 2Y0KA 3C5OA 4GCQA 4G9QA 1MM4A 2OYOA 3A2SX 2O4DA 5DL6A 3O0EA 4QQ1A 1HXTA 4F4BA 2GMYA 2KDYA 3WI4A 1PHOA 2PRNA 4FMSA 2ODJA 4E1SA 4AYDC 5DL5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AA7 A;  3AA7 B;  5AFU L;  3AA6 A;  3LK4 1;  5AFU K;  3LK2 A;  3AA6 B;  3LK2 B;  2KZ7 A;  3LK3 B;  4AKR A;  3AAA A;  3LK3 A;  2KXP A;  2KZ7 B;  4AKR B;  3AAA B;  2KXP B;  1IZN B;  1IZN A;  5ADX L;  3AA1 A;  5ADX K;  3AA1 B;  3AA0 A;  3AA0 B;  3AAE B;  3AAE A;  3LK4 2; 
#chains in the Genus database with same CATH topology
 4PR7 A;  4O4U A;  2MNH A;  2Y7S A;  4D5U A;  4CTD A;  2WVP A;  5PRN A;  3HW9 A;  3VE1 A;  4O49 A;  1P8C A;  5JDP A;  4AYN A;  3AA0 B;  1GU9 A;  3NSG A;  4N59 A;  4XNK A;  3AAE A;  4JCH A;  1MPF A;  3BEY A;  3NJT A;  3A0H O;  2ES9 A;  3UAQ A;  2JMM A;  4AFK A;  3DA3 A;  3POQ A;  5AFU L;  5AFU K;  2ZLD A;  2XMX A;  2IJC A;  3LK3 B;  6PRN A;  3SYB A;  3VZT X;  1GFP A;  2W80 C;  2YPV A;  2IWV A;  8PRN A;  2GE4 A;  3LK4 2;  3SZV A;  3HWB A;  3A0B O;  3AA6 A;  4N74 A;  1T16 A;  2IWW A;  4AKR A;  1Q9F A;  1IZN A;  2WJQ A;  3T0S A;  1LW1 A;  4K3B A;  2AF7 A;  4D65 A;  3AAE B;  1YS5 A;  4FQE A;  1OSM A;  3KVD D;  4K3C A;  2WJR A;  4U9C A;  3AAA B;  1T1L A;  3DZM A;  3AA1 A;  4G9Q A;  1MM4 A;  2OYO A;  2GMY A;  2KDY A;  3KZI O;  1PHO A;  3POU A;  4N75 A;  3FYX A;  5D5D A;  1ZHW A;  4IL6 O;  1HXU A;  3HOE A;  2K0L A;  1OPF A;  3PQU A;  4FZM A;  1BH3 A;  1S5L O;  1IZN B;  4FZN A;  1GFO A;  1QJ9 A;  2MHL A;  1QJP A;  1THQ A;  4LSH A;  4RJX A;  4O4X A;  5GV0 A;  4FES A;  3EMN X;  3VZW X;  4PJ0 O;  1QJ8 A;  2X27 X;  1Q9G A;  3UU2 A;  4LSE A;  1H6S 1;  5DIP A;  4D64 A;  4UB8 O;  2KC0 A;  4LSF A;  1ORM A;  5GTI O;  2PFX A;  4KR8 A;  5B5E O;  4C4V A;  3DWN A;  2OUW A;  4FRX A;  2AXT O;  3LK2 A;  3SY9 A;  2KZ7 A;  4AUI A;  4Z3T A;  4FOZ A;  4AYE C;  4FRT A;  4F4B A;  1VKE A;  1PRN A;  4G76 A;  3WI5 A;  4C69 X;  4GF4 A;  4G75 A;  2J1N A;  3BS0 A;  5DIK A;  5KAF O;  4RLC A;  2Y0L A;  5T5F A;  4XNL A;  1GFM A;  4KR4 A;  2XG6 A;  3SY7 A;  2ZFG A;  1ME5 A;  3G7G A;  4C00 A;  4GHB A;  3D7I A;  2F1T A;  5FVN A;  5IYU A;  2J4U P;  2XE3 A;  2KXP A;  2F1V A;  3K19 A;  3QRA A;  1P4T A;  2LFU A;  3A2S X;  5G39 A;  3O0E A;  3WI4 A;  4FMS A;  4E1S A;  5DL5 A;  4C4V B;  3AA7 A;  3RBH A;  5DL7 A;  3LK2 B;  3BRY A;  2R89 A;  4AZL A;  4RLB A;  4O3W A;  3VY8 X;  4FT6 A;  4N58 A;  2QEU A;  2Q0T A;  3PF1 A;  2POR A;  2XE2 A;  4UB6 O;  2FGR A;  3WU2 O;  3AA6 B;  2N2L A;  4AKR B;  1GFN A;  5DL8 A;  4O3Z A;  4LSI A;  2XE1 A;  2XE5 A;  2QTK A;  3HOL A;  5G38 A;  3AA0 A;  2JN8 A;  3SYS A;  3QRC A;  4FSO A;  3VY9 X;  4FZL A;  5TIS O;  1BXW A;  2K4T A;  4E1T A;  3BRZ A;  3LVY A;  3GP6 A;  3PRN A;  4GCS A;  3PGS A;  1E54 A;  2FGQ X;  1G90 A;  1ZHT A;  3AA1 B;  4O3Y A;  2R4O A;  2XTR A;  2R8A A;  3PGR A;  1ZHZ A;  3DA4 A;  2Y2X A;  3T24 A;  2OMF A;  5KAI O;  2CWQ A;  3POX A;  4PUX A;  3C5O A;  2O4D A;  4QQ1 A;  1HXT A;  2PRN A;  4AYD C;  5H2F O;  2XTQ A;  1ZHX A;  3AAA A;  4FUV A;  4RJW A;  5ADX L;  3PQS A;  5ADX K;  5EE2 A;  5G3A A;  3JCU O;  4AKM A;  3SZD A;  5G26 A;  1GFQ A;  3VE2 A;  4B61 A;  2YNK A;  7PRN A;  2M06 A;  1HXX A;  3T20 A;  2KZ7 B;  4GCP A;  2M07 A;  2N2M A;  2R4L A;  2F1C X;  3TZG A;  3PGU A;  4AYI D;  1ZHY A;  2R4N A;  2W81 C;  3V8U A;  3UPG A;  2R88 A;  4FSP A;  5GTH O;  1BT9 A;  3VZU X;  4KRA A;  4RL9 A;  3C1L A;  2LHF A;  2KXP B;  2JQY A;  3POR A;  1MM5 A;  5E79 O;  5B66 O;  2R4P A;  2O4V A;  2X9K A;  2PRR A;  4AYM C;  3JTY A;  3AA7 B;  2Y0H A;  4BUM X;  3LK4 1;  3DWO X;  4O3X B;  3LK3 A;  4JFB A;  2ERV A;  1KNC A;  2Y0K A;  4GCQ A;  5DL6 A;  2ODJ A; 
#chains in the Genus database with same CATH homology
 3POU A;  3FYX A;  5D5D A;  4O4U A;  3AA7 A;  1ZHW A;  2MNH A;  2Y7S A;  4D5U A;  1HXU A;  3HOE A;  3RBH A;  5DL7 A;  2XTQ A;  1ZHX A;  2K0L A;  3LK2 B;  3AAA A;  1OPF A;  3PQU A;  4FZM A;  1BH3 A;  4O3W A;  4RLB A;  4AZL A;  1IZN B;  3VY8 X;  4FUV A;  4FZN A;  4FT6 A;  5PRN A;  4RJW A;  1GFO A;  3HW9 A;  5ADX L;  3PQS A;  1QJ9 A;  4N58 A;  5ADX K;  2MHL A;  5EE2 A;  3VE1 A;  1QJP A;  2QEU A;  4O49 A;  1THQ A;  4LSH A;  4RJX A;  4O4X A;  1P8C A;  5JDP A;  2Q0T A;  4AKM A;  4AYN A;  3AA0 B;  1GU9 A;  2POR A;  2XE2 A;  3NSG A;  3AAE A;  4N59 A;  4JCH A;  2FGR A;  4XNK A;  3SZD A;  1MPF A;  5GV0 A;  3BEY A;  4FES A;  3EMN X;  3VZW X;  5G26 A;  2ES9 A;  3UAQ A;  1GFQ A;  2JMM A;  1QJ8 A;  3VE2 A;  2X27 X;  4B61 A;  2YNK A;  4AFK A;  7PRN A;  1Q9G A;  3DA3 A;  3POQ A;  3UU2 A;  2M06 A;  4LSE A;  5AFU L;  1H6S 1;  5AFU K;  2ZLD A;  1HXX A;  2XMX A;  3AA6 B;  4AYE C;  3T20 A;  2IJC A;  3LK3 B;  6PRN A;  2KZ7 B;  2N2L A;  5DIP A;  4AKR B;  1GFN A;  4GCP A;  3SYB A;  2M07 A;  5DL8 A;  4D64 A;  4O3Z A;  2KC0 A;  2N2M A;  3VZT X;  1GFP A;  4LSI A;  2XE1 A;  4LSF A;  1ORM A;  2W80 C;  2XE5 A;  2YPV A;  3TZG A;  2QTK A;  4AYI D;  3HOL A;  1ZHY A;  3AA0 A;  2JN8 A;  3SYS A;  2PFX A;  8PRN A;  2GE4 A;  3LK4 2;  4KR8 A;  2W81 C;  3QRC A;  4FSO A;  3V8U A;  3VY9 X;  4FZL A;  3SZV A;  3UPG A;  4FSP A;  1BT9 A;  3HWB A;  1BXW A;  2K4T A;  3VZU X;  4E1T A;  2OUW A;  3AA6 A;  4FRX A;  4KRA A;  3LK2 A;  3SY9 A;  4RL9 A;  2KZ7 A;  4AUI A;  4Z3T A;  4FOZ A;  4AKR A;  3C1L A;  3LVY A;  1Q9F A;  2LHF A;  3GP6 A;  2KXP B;  3PRN A;  4FRT A;  3POR A;  4GCS A;  1VKE A;  1IZN A;  1MM5 A;  1PRN A;  4G76 A;  4GF4 A;  1E54 A;  2FGQ X;  2J1N A;  4G75 A;  3WI5 A;  1ZHT A;  4C69 X;  3T0S A;  1G90 A;  3AA1 B;  5DIK A;  4O3Y A;  4RLC A;  2Y0L A;  5T5F A;  4XNL A;  1GFM A;  1LW1 A;  4KR4 A;  2O4V A;  2AF7 A;  2XG6 A;  3SY7 A;  4D65 A;  2XTR A;  2ZFG A;  3AAE B;  1ME5 A;  2PRR A;  3G7G A;  1YS5 A;  4GHB A;  4AYM C;  1ZHZ A;  3JTY A;  3D7I A;  1OSM A;  3AA7 B;  2Y0H A;  3DA4 A;  2F1T A;  3KVD D;  5FVN A;  5IYU A;  2Y2X A;  4BUM X;  2J4U P;  3T24 A;  3LK4 1;  2XE3 A;  2OMF A;  4U9C A;  4O3X B;  3LK3 A;  2KXP A;  3AAA B;  2F1V A;  4JFB A;  2CWQ A;  3K19 A;  3QRA A;  1P4T A;  2LFU A;  2ERV A;  1KNC A;  3POX A;  3AA1 A;  4PUX A;  2Y0K A;  3C5O A;  4GCQ A;  4G9Q A;  1MM4 A;  2OYO A;  3A2S X;  2O4D A;  5DL6 A;  3O0E A;  4QQ1 A;  1HXT A;  4F4B A;  2GMY A;  2KDY A;  3WI4 A;  1PHO A;  2PRN A;  4FMS A;  2ODJ A;  4E1S A;  4AYD C;  5DL5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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