5AFUK

Cryo-em structure of dynein tail-dynactin-bicd2n complex
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
275
structure length
275
Chain Sequence
RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYEDQVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPEEVDGSLKSWRESCDSALRAYVKDHYSNGFCTVYAKNIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSVTVSNEAQTAKEFIKIIEHAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structure of the Dynactin Complex and its Interaction with Dynein.
pubmed doi rcsb
molecule tags Motor protein
molecule keywords DYNEIN TAIL
total genus 65
structure length 275
sequence length 275
ec nomenclature
pdb deposition date 2015-01-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 5afuK01
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 5afuK02
4AKRA 1IZNB 3AA0A 3AA6B 3AA1A 5ADXK 1IZNA 4AKRB 2KZ7A 3AA0B 3AA6A 5AFUL 3LK3A 3AAEB 5ADXL 3AAAB 3LK41 3AAEA 3AA7A 3AA1B 2KXPA 2KZ7B 3LK2B 3AA7B 5AFUK 2KXPB 3LK42 3AAAA 3LK3B 3LK2A
chains in the Genus database with same CATH superfamily
1H6S1 1ZHTA 4CTDA 4LSIA 4AKRA 2ERVA 3POUA 3AA0A 1LW1A 2FGQX 3DA3A 4FMSA 1GFMA 4RJXA 4AZLA 2OMFA 1PHOA 3HOLA 2XG6A 3AA6A 1GFOA 1ZHXA 3AAEB 3RBHA 1VKEA 2KDYA 3A2SX 4FZLA 1MM4A 4AYID 1QJPA 3AAAB 2AF7A 2K0LA 1MPFA 3DWOX 4N59A 2CWQA 2O4VA 2XMXA 2YNKA 4FZNA 5KAFO 2GMYA 3VE1A 2KXPA 4O3WA 4JCHA 1GU9A 1THQA 1S5LO 2AXTO 4XNLA 3AA7B 2Y0LA 3DWNA 5AFUK 2W80C 4O3ZA 4RJWA 3NJTA 4N75A 2WJRA 3KZIO 1QJ9A 4O4XA 4B61A 4Z3TA 4FZMA 2F1CX 2QEUA 2F1TA 4FQEA 3DA4A 2W81C 2M06A 5IYUA 4C69X 5DIPA 1ZHYA 2M07A 1HXUA 1P8CA 2R88A 4KR4A 4AYDC 4FESA 2J1NA 2R8AA 2XE1A 3SYSA 3VZTX 5G26A 5PRNA 4LSHA 1T16A 2OUWA 1IZNB 5H2FO 1Q9GA 4G9QA 3BEYA 3PQSA 4D5UA 5GV0A 2XTRA 4K3CA 2N2MA 1YS5A 4PUXA 5GTIO 3PF1A 3D7IA 2X9KA 3SYBA 3AA0B 4UB8O 3PRNA 5AFUL 5KAIO 1GFNA 2Y0KA 1PRNA 3DZMA 2Q0TA 3PORA 3T0SA 2ZLDA 5ADXL 5DL5A 2KC0A 5DL8A 3LK41 3BRZA 3FYXA 4JFBA 2MNHA 5FVNA 2PRNA 1HXXA 3VZUX 4PJ0O 4LSFA 3JTYA 1ORMA 3K19A 4IL6O 4O49A 5G38A 3TZGA 3VZWX 4AUIA 4O4UA 3WU2O 3AAAA 3QRCA 3SZVA 2LFUA 4N74A 4U9CA 4O3YA 5TISO 3T20A 3BS0A 2PRRA 3LK3B 5G3AA 3V8UA 1ME5A 2IJCA 2R4PA 1G90A 4GF4A 4XNKA 1GFPA 3PGRA 2R89A 3AA1A 5EE2A 5ADXK 2R4LA 3PQUA 3SY9A 4AKRB 5T5FA 5B5EO 2JQYA 4LSEA 3C5OA 3LK3A 2PORA 4AYMC 4RLCA 4C00A 4FOZA 1OPFA 4FRTA 3SY7A 1MM5A 4AKMA 3AAEA 2LHFA 4GCSA 5DL7A 3WI4A 4C4VB 2XE5A 3KVDD 1Q9FA 4KRAA 1KNCA 1T1LA 3GP6A 3PGUA 3PGSA 4E1SA 3C1LA 2KXPB 5E79O 2PFXA 1E54A 2F1VA 2IWVA 5D5DA 4FRXA 2J4UP 1BXWA 3LK42 4F4BA 5GTHO 2QTKA 4O3XB 4RL9A 2O4DA 4GHBA 3UAQA 2R4NA 3UU2A 2Y0HA 4GCQA 2FGRA 2GE4A 1QJ8A 6PRNA 2ODJA 3VY8X 3HOEA 4RLBA 4FT6A 3HW9A 5DL6A 3POXA 2WVPA 4AYEC 4BUMX 2K4TA 3UPGA 5B66O 5DIKA 1OSMA 2N2LA 3AA6B 4FSPA 1BT9A 1IZNA 1P4TA 2KZ7A 4AFKA 5JDPA 1ZHWA 4FSOA 4K3BA 1ZHZA 2JN8A 3G7GA 3LVYA 4QQ1A 3BRYA 3WI5A 2ES9A 2Y7SA 3POQA 3T24A 2XE2A 4N58A 2JMMA 2WJQA 4UB6O 2MHLA 3AA7A 3EMNX 3NSGA 3AA1B 4G76A 1GFQA 3HWBA 4GCPA 2KZ7B 3VE2A 2R4OA 2OYOA 3LK2B 4C4VA 3A0BO 7PRNA 2ZFGA 4AYNA 2XE3A 2Y2XA 2IWWA 3O0EA 5G39A 4G75A 3SZDA 4E1TA 1BH3A 4KR8A 3A0HO 1HXTA 3QRAA 3JCUO 4PR7A 4D64A 3VY9X 4D65A 2YPVA 2XTQA 2X27X 8PRNA 3LK2A 4FUVA
chains in the Genus database with same CATH topology
1H6S1 1ZHTA 4LSIA 4AKRA 2ERVA 3POUA 3AA0A 1LW1A 2FGQX 3DA3A 4FMSA 1GFMA 4RJXA 4AZLA 2OMFA 1PHOA 3HOLA 2XG6A 3AA6A 1GFOA 1ZHXA 3AAEB 1VKEA 2KDYA 3A2SX 4FZLA 1MM4A 4AYID 1QJPA 3AAAB 2AF7A 2K0LA 1MPFA 4N59A 2CWQA 2O4VA 2XMXA 2YNKA 4FZNA 3VE1A 2GMYA 2KXPA 4O3WA 4JCHA 1GU9A 1THQA 4XNLA 3AA7B 2Y0LA 3SYSA 5AFUK 2W80C 4O3ZA 4RJWA 3RBHA 4D5UA 4D65A 4B61A 1QJ9A 4O4XA 4Z3TA 4FZMA 2QEUA 2F1TA 3DA4A 2W81C 2M06A 5IYUA 4C69X 5DIPA 1ZHYA 2M07A 1HXUA 1P8CA 4AYDC 4KR4A 4FESA 2J1NA 2XE1A 3VZTX 5G26A 5PRNA 4LSHA 2OUWA 1IZNB 1Q9GA 4G9QA 3BEYA 3PQSA 5GV0A 2XTRA 4PUXA 2N2MA 1YS5A 3D7IA 3SYBA 3AA0B 3PRNA 5AFUL 1GFNA 2Y0KA 1PRNA 2Q0TA 3PORA 3T0SA 2ZLDA 5ADXL 5DL5A 2KC0A 5DL8A 3LK41 3FYXA 4JFBA 2MNHA 5FVNA 2PRNA 1HXXA 3VZUX 4LSFA 3JTYA 1ORMA 3K19A 4O49A 3TZGA 3VZWX 4AUIA 4O4UA 3AAAA 3QRCA 3SZVA 2LFUA 4U9CA 4O3YA 3T20A 2PRRA 3LK3B 3V8UA 1ME5A 2IJCA 1G90A 4GF4A 4XNKA 1GFPA 3AA1A 5EE2A 5ADXK 3PQUA 3SY9A 4AKRB 5T5FA 4LSEA 3C5OA 3LK3A 2PORA 4AYMC 4RLCA 4FOZA 1OPFA 4FRTA 3SY7A 1MM5A 4AKMA 3AAEA 2LHFA 4GCSA 5DL7A 3WI4A 2XE5A 3KVDD 1Q9FA 4KRAA 1KNCA 3GP6A 4E1SA 3C1LA 2KXPB 2PFXA 1E54A 2F1VA 5D5DA 4FRXA 2J4UP 1BXWA 3LK42 4F4BA 2QTKA 4O3XB 4RL9A 2O4DA 4GHBA 3UAQA 3UU2A 3WI5A 2Y0HA 4GCQA 2FGRA 2GE4A 1QJ8A 6PRNA 2ODJA 3VY8X 3HOEA 4RLBA 4FT6A 3HW9A 5DL6A 3POXA 4BUMX 4AYEC 3UPGA 2K4TA 5DIKA 1OSMA 2N2LA 3AA6B 4FSPA 1BT9A 1IZNA 1P4TA 2KZ7A 4AFKA 5JDPA 1ZHWA 4FSOA 1ZHZA 2JN8A 3G7GA 3LVYA 4QQ1A 2ES9A 2Y7SA 3POQA 3T24A 2XE2A 4N58A 2JMMA 2MHLA 3AA7A 3EMNX 3NSGA 3AA1B 4G76A 1GFQA 3HWBA 4GCPA 2KZ7B 3VE2A 2OYOA 3LK2B 7PRNA 2ZFGA 4AYNA 2XE3A 2Y2XA 3O0EA 4G75A 3SZDA 4E1TA 1BH3A 4KR8A 1HXTA 3QRAA 4D64A 3VY9X 2YPVA 2XTQA 2X27X 8PRNA 3LK2A 4FUVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AKR A;  1IZN B;  3AA0 A;  3AA6 B;  3AA1 A;  5ADX K;  1IZN A;  4AKR B;  2KZ7 A;  3AA0 B;  3AA6 A;  5AFU L;  3LK3 A;  3AAE B;  5ADX L;  3AAA B;  3LK4 1;  3AAE A;  3AA7 A;  3AA1 B;  2KXP A;  2KZ7 B;  3LK2 B;  3AA7 B;  5AFU K;  2KXP B;  3LK4 2;  3AAA A;  3LK3 B;  3LK2 A; 
#chains in the Genus database with same CATH topology
 1H6S 1;  1ZHT A;  4CTD A;  4LSI A;  4AKR A;  2ERV A;  3POU A;  3AA0 A;  1LW1 A;  2FGQ X;  3DA3 A;  4FMS A;  1GFM A;  4RJX A;  4AZL A;  2OMF A;  1PHO A;  3HOL A;  2XG6 A;  3AA6 A;  1GFO A;  1ZHX A;  3AAE B;  3RBH A;  1VKE A;  2KDY A;  3A2S X;  4FZL A;  1MM4 A;  4AYI D;  1QJP A;  3AAA B;  2AF7 A;  2K0L A;  1MPF A;  3DWO X;  4N59 A;  2CWQ A;  2O4V A;  2XMX A;  2YNK A;  4FZN A;  5KAF O;  2GMY A;  3VE1 A;  2KXP A;  4O3W A;  4JCH A;  1GU9 A;  1THQ A;  1S5L O;  2AXT O;  4XNL A;  3AA7 B;  2Y0L A;  3DWN A;  5AFU K;  2W80 C;  4O3Z A;  4RJW A;  3NJT A;  4N75 A;  2WJR A;  3KZI O;  1QJ9 A;  4O4X A;  4B61 A;  4Z3T A;  4FZM A;  2F1C X;  2QEU A;  2F1T A;  4FQE A;  3DA4 A;  2W81 C;  2M06 A;  5IYU A;  4C69 X;  5DIP A;  1ZHY A;  2M07 A;  1HXU A;  1P8C A;  2R88 A;  4KR4 A;  4AYD C;  4FES A;  2J1N A;  2R8A A;  2XE1 A;  3SYS A;  3VZT X;  5G26 A;  5PRN A;  4LSH A;  1T16 A;  2OUW A;  1IZN B;  5H2F O;  1Q9G A;  4G9Q A;  3BEY A;  3PQS A;  4D5U A;  5GV0 A;  2XTR A;  4K3C A;  2N2M A;  1YS5 A;  4PUX A;  5GTI O;  3PF1 A;  3D7I A;  2X9K A;  3SYB A;  3AA0 B;  4UB8 O;  3PRN A;  5AFU L;  5KAI O;  1GFN A;  2Y0K A;  1PRN A;  3DZM A;  2Q0T A;  3POR A;  3T0S A;  2ZLD A;  5ADX L;  5DL5 A;  2KC0 A;  5DL8 A;  3LK4 1;  3BRZ A;  3FYX A;  4JFB A;  2MNH A;  5FVN A;  2PRN A;  1HXX A;  3VZU X;  4PJ0 O;  4LSF A;  3JTY A;  1ORM A;  3K19 A;  4IL6 O;  4O49 A;  5G38 A;  3TZG A;  3VZW X;  4AUI A;  4O4U A;  3WU2 O;  3AAA A;  3QRC A;  3SZV A;  2LFU A;  4N74 A;  4U9C A;  4O3Y A;  5TIS O;  3T20 A;  3BS0 A;  2PRR A;  3LK3 B;  5G3A A;  3V8U A;  1ME5 A;  2IJC A;  2R4P A;  1G90 A;  4GF4 A;  4XNK A;  1GFP A;  3PGR A;  2R89 A;  3AA1 A;  5EE2 A;  5ADX K;  2R4L A;  3PQU A;  3SY9 A;  4AKR B;  5T5F A;  5B5E O;  2JQY A;  4LSE A;  3C5O A;  3LK3 A;  2POR A;  4AYM C;  4RLC A;  4C00 A;  4FOZ A;  1OPF A;  4FRT A;  3SY7 A;  1MM5 A;  4AKM A;  3AAE A;  2LHF A;  4GCS A;  5DL7 A;  3WI4 A;  4C4V B;  2XE5 A;  3KVD D;  1Q9F A;  4KRA A;  1KNC A;  1T1L A;  3GP6 A;  3PGU A;  3PGS A;  4E1S A;  3C1L A;  2KXP B;  5E79 O;  2PFX A;  1E54 A;  2F1V A;  2IWV A;  5D5D A;  4FRX A;  2J4U P;  1BXW A;  3LK4 2;  4F4B A;  5GTH O;  2QTK A;  4O3X B;  4RL9 A;  2O4D A;  4GHB A;  3UAQ A;  2R4N A;  3UU2 A;  2Y0H A;  4GCQ A;  2FGR A;  2GE4 A;  1QJ8 A;  6PRN A;  2ODJ A;  3VY8 X;  3HOE A;  4RLB A;  4FT6 A;  3HW9 A;  5DL6 A;  3POX A;  2WVP A;  4AYE C;  4BUM X;  2K4T A;  3UPG A;  5B66 O;  5DIK A;  1OSM A;  2N2L A;  3AA6 B;  4FSP A;  1BT9 A;  1IZN A;  1P4T A;  2KZ7 A;  4AFK A;  5JDP A;  1ZHW A;  4FSO A;  4K3B A;  1ZHZ A;  2JN8 A;  3G7G A;  3LVY A;  4QQ1 A;  3BRY A;  3WI5 A;  2ES9 A;  2Y7S A;  3POQ A;  3T24 A;  2XE2 A;  4N58 A;  2JMM A;  2WJQ A;  4UB6 O;  2MHL A;  3AA7 A;  3EMN X;  3NSG A;  3AA1 B;  4G76 A;  1GFQ A;  3HWB A;  4GCP A;  2KZ7 B;  3VE2 A;  2R4O A;  2OYO A;  3LK2 B;  4C4V A;  3A0B O;  7PRN A;  2ZFG A;  4AYN A;  2XE3 A;  2Y2X A;  2IWW A;  3O0E A;  5G39 A;  4G75 A;  3SZD A;  4E1T A;  1BH3 A;  4KR8 A;  3A0H O;  1HXT A;  3QRA A;  3JCU O;  4PR7 A;  4D64 A;  3VY9 X;  4D65 A;  2YPV A;  2XTQ A;  2X27 X;  8PRN A;  3LK2 A;  4FUV A; 
#chains in the Genus database with same CATH homology
 1H6S 1;  1ZHT A;  4LSI A;  4AKR A;  2ERV A;  3POU A;  3AA0 A;  1LW1 A;  2FGQ X;  3DA3 A;  4FMS A;  1GFM A;  4RJX A;  4AZL A;  2OMF A;  1PHO A;  3HOL A;  2XG6 A;  3AA6 A;  1GFO A;  1ZHX A;  3AAE B;  1VKE A;  2KDY A;  3A2S X;  4FZL A;  1MM4 A;  4AYI D;  1QJP A;  3AAA B;  2AF7 A;  2K0L A;  1MPF A;  4N59 A;  2CWQ A;  2O4V A;  2XMX A;  2YNK A;  4FZN A;  3VE1 A;  2GMY A;  2KXP A;  4O3W A;  4JCH A;  1GU9 A;  1THQ A;  4XNL A;  3AA7 B;  2Y0L A;  3SYS A;  5AFU K;  2W80 C;  4O3Z A;  4RJW A;  3RBH A;  4D5U A;  4D65 A;  4B61 A;  1QJ9 A;  4O4X A;  4Z3T A;  4FZM A;  2QEU A;  2F1T A;  3DA4 A;  2W81 C;  2M06 A;  5IYU A;  4C69 X;  5DIP A;  1ZHY A;  2M07 A;  1HXU A;  1P8C A;  4AYD C;  4KR4 A;  4FES A;  2J1N A;  2XE1 A;  3VZT X;  5G26 A;  5PRN A;  4LSH A;  2OUW A;  1IZN B;  1Q9G A;  4G9Q A;  3BEY A;  3PQS A;  5GV0 A;  2XTR A;  4PUX A;  2N2M A;  1YS5 A;  3D7I A;  3SYB A;  3AA0 B;  3PRN A;  5AFU L;  1GFN A;  2Y0K A;  1PRN A;  2Q0T A;  3POR A;  3T0S A;  2ZLD A;  5ADX L;  5DL5 A;  2KC0 A;  5DL8 A;  3LK4 1;  3FYX A;  4JFB A;  2MNH A;  5FVN A;  2PRN A;  1HXX A;  3VZU X;  4LSF A;  3JTY A;  1ORM A;  3K19 A;  4O49 A;  3TZG A;  3VZW X;  4AUI A;  4O4U A;  3AAA A;  3QRC A;  3SZV A;  2LFU A;  4U9C A;  4O3Y A;  3T20 A;  2PRR A;  3LK3 B;  3V8U A;  1ME5 A;  2IJC A;  1G90 A;  4GF4 A;  4XNK A;  1GFP A;  3AA1 A;  5EE2 A;  5ADX K;  3PQU A;  3SY9 A;  4AKR B;  5T5F A;  4LSE A;  3C5O A;  3LK3 A;  2POR A;  4AYM C;  4RLC A;  4FOZ A;  1OPF A;  4FRT A;  3SY7 A;  1MM5 A;  4AKM A;  3AAE A;  2LHF A;  4GCS A;  5DL7 A;  3WI4 A;  2XE5 A;  3KVD D;  1Q9F A;  4KRA A;  1KNC A;  3GP6 A;  4E1S A;  3C1L A;  2KXP B;  2PFX A;  1E54 A;  2F1V A;  5D5D A;  4FRX A;  2J4U P;  1BXW A;  3LK4 2;  4F4B A;  2QTK A;  4O3X B;  4RL9 A;  2O4D A;  4GHB A;  3UAQ A;  3UU2 A;  3WI5 A;  2Y0H A;  4GCQ A;  2FGR A;  2GE4 A;  1QJ8 A;  6PRN A;  2ODJ A;  3VY8 X;  3HOE A;  4RLB A;  4FT6 A;  3HW9 A;  5DL6 A;  3POX A;  4BUM X;  4AYE C;  3UPG A;  2K4T A;  5DIK A;  1OSM A;  2N2L A;  3AA6 B;  4FSP A;  1BT9 A;  1IZN A;  1P4T A;  2KZ7 A;  4AFK A;  5JDP A;  1ZHW A;  4FSO A;  1ZHZ A;  2JN8 A;  3G7G A;  3LVY A;  4QQ1 A;  2ES9 A;  2Y7S A;  3POQ A;  3T24 A;  2XE2 A;  4N58 A;  2JMM A;  2MHL A;  3AA7 A;  3EMN X;  3NSG A;  3AA1 B;  4G76 A;  1GFQ A;  3HWB A;  4GCP A;  2KZ7 B;  3VE2 A;  2OYO A;  3LK2 B;  7PRN A;  2ZFG A;  4AYN A;  2XE3 A;  2Y2X A;  3O0E A;  4G75 A;  3SZD A;  4E1T A;  1BH3 A;  4KR8 A;  1HXT A;  3QRA A;  4D64 A;  3VY9 X;  2YPV A;  2XTQ A;  2X27 X;  8PRN A;  3LK2 A;  4FUV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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