3LK3A

Crystal structure of capz bound to the cpi and csi uncapping motifs from carmil
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
270
structure length
266
Chain Sequence
RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYDDQVLITEHGDLGNGRFLDPRNKISFKFDHLRKEASDPQPEDLKQWRDACDSALRAYVKDHYPNGFCTVYGKSIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVAAVLKIQVHYYEDGNVQLVSHKDIQDSVQVSSDVQTAKEFIKIIENAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural characterization of a capping protein interaction motif defines a family of actin filament regulators
doi rcsb
source organism Gallus gallus
molecule tags Protein binding
molecule keywords F-actin-capping protein subunit alpha-1
total genus 76
structure length 266
sequence length 270
ec nomenclature
pdb deposition date 2010-01-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01267 F-actin_cap_A F-actin capping protein alpha subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 3lk3A01
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 3lk3A02
3LK42 2KXPA 3LK2A 2KZ7B 3AA7B 3LK3A 1IZNA 4AKRB 3AA0A 3LK2B 5ADXK 3AA0B 4AKRA 5ADXL 3AA6A 2KZ7A 3AA7A 5AFUK 1IZNB 3LK3B 3AAAB 3AAAA 3LK41 2KXPB 3AA6B 5AFUL 3AA1B 3AAEA 3AAEB 3AA1A
chains in the Genus database with same CATH superfamily
1MPFA 1S5LO 2PORA 4UB6O 2X27X 2WJRA 4E1SA 2PFXA 2KC0A 5GTHO 1P8CA 5G38A 4O4XA 2XE5A 3AA7B 3KVDD 1QJ9A 2F1TA 2XG6A 2R8AA 4N58A 2YPVA 3WI5A 4FSPA 4FMSA 4K3BA 2MNHA 5IYUA 1MM5A 5GV0A 3AA0A 2K4TA 3DA3A 4FZMA 5KAFO 4PR7A 4AFKA 4IL6O 1G90A 3AA0B 4O49A 3VZUX 5G26A 4D5UA 4G75A 4KR8A 3HW9A 2IJCA 1VKEA 4AYNA 3UU2A 3SZDA 3AA7A 3A2SX 2OYOA 4N59A 3LK3B 2AF7A 1YS5A 2R4NA 3PGRA 3A0HO 2QEUA 2Q0TA 3EMNX 5DL7A 2Y7SA 3VZWX 4AUIA 4C69X 3T0SA 1GU9A 1QJ8A 2XTRA 2JMMA 3POUA 8PRNA 3KZIO 2FGRA 4KR4A 4N74A 3AAEA 2N2LA 2ZFGA 1MM4A 5DL5A 6PRNA 2GMYA 2WVPA 3PGUA 4UB8O 3WU2O 5G3AA 2XE1A 2IWVA 3LK2A 1THQA 1IZNA 4LSIA 5H2FO 4AYEC 5FVNA 1H6S1 1GFMA 3QRAA 4GCPA 2K0LA 3HWBA 5DIKA 4O4UA 1HXXA 4AYDC 1T16A 4AZLA 2OUWA 2F1CX 4FZNA 4RJXA 4AYID 2XE2A 5ADXK 4RL9A 2PRRA 1OPFA 2ZLDA 1Q9FA 2WJQA 4FUVA 4GHBA 2M06A 5DL8A 1T1LA 5EE2A 1ZHTA 2PRNA 3SY7A 3TZGA 3VE2A 4Z3TA 3AA6A 2W81C 4FRXA 1LW1A 1Q9GA 2FGQX 5D5DA 2XE3A 1E54A 3GP6A 4FRTA 2KXPB 4LSHA 3JCUO 1GFNA 1ORMA 1HXUA 4O3YA 3VZTX 2IWWA 4FT6A 2R4PA 4JCHA 3AA1A 4KRAA 4RLCA 3O0EA 3BS0A 3PQSA 2XTQA 2KXPA 2R4LA 1ME5A 3V8UA 1BT9A 3QRCA 2KZ7B 1ZHZA 4PUXA 2MHLA 2Y0HA 3PRNA 3HOLA 4O3WA 1ZHXA 4XNKA 3HOEA 4AKRB 5TISO 3PORA 1KNCA 3PGSA 1GFQA 1BH3A 2W80C 2ERVA 3DZMA 5DL6A 2O4DA 2YNKA 4FESA 4N75A 1QJPA 2Y2XA 3DA4A 3JTYA 2Y0KA 4O3ZA 3C5OA 4AKMA 4O3XB 4G9QA 2OMFA 2JN8A 1BXWA 2N2MA 2KZ7A 4U9CA 5E79O 4AYMC 5JDPA 4G76A 3POQA 4B61A 1IZNB 1PRNA 1ZHYA 3G7GA 3SZVA 3SYBA 3PQUA 3LVYA 4E1TA 7PRNA 4RLBA 3AA6B 3VY8X 2R89A 3AA1B 3BRYA 4CTDA 1ZHWA 3AAEB 5G39A 5GTIO 5PRNA 3D7IA 3A0BO 3BEYA 4BUMX 1GFOA 5KAIO 1P4TA 3DWOX 1PHOA 2CWQA 5DIPA 3LK42 4FZLA 4GCQA 3SY9A 1OSMA 3NSGA 5B5EO 3LK3A 3POXA 3K19A 3RBHA 4D64A 4GF4A 2J1NA 2O4VA 4FSOA 5B66O 4C00A 2R4OA 3NJTA 3WI4A 3LK2B 3FYXA 3C1LA 3VY9X 2KDYA 4JFBA 5T5FA 4GCSA 3UAQA 1GFPA 1HXTA 3BRZA 4AKRA 3SYSA 3VE1A 4PJ0O 4LSFA 4QQ1A 2ES9A 2Y0LA 3UPGA 2GE4A 2XMXA 2R88A 4K3CA 2X9KA 4RJWA 5AFUK 4C4VB 3PF1A 5ADXL 2LFUA 3T24A 2F1VA 2ODJA 2J4UP 3AAAB 3AAAA 4F4BA 3LK41 4D65A 3DWNA 2QTKA 3T20A 4XNLA 4FQEA 4LSEA 4C4VA 5AFUL 4FOZA 2M07A 2LHFA 2AXTO 2JQYA
chains in the Genus database with same CATH topology
1MPFA 2PORA 2X27X 4E1SA 2PFXA 2KC0A 1P8CA 4O4XA 2XE5A 3AA7B 3KVDD 1QJ9A 2F1TA 2XG6A 4N58A 3WI5A 2YPVA 5IYUA 4FSPA 4FMSA 2MNHA 1MM5A 5GV0A 3AA0A 2K4TA 3DA3A 4FZMA 4AFKA 1G90A 3AA0B 4O49A 3VZUX 5G26A 4D5UA 4G75A 4KR8A 3HW9A 2IJCA 1VKEA 4AYNA 3UU2A 3SZDA 3AA7A 3A2SX 2OYOA 4N59A 3LK3B 2AF7A 1YS5A 4C69X 2QEUA 2Q0TA 3EMNX 5DL7A 2Y7SA 3VZWX 4AUIA 3T0SA 1GU9A 1QJ8A 2XTRA 2JMMA 3POUA 8PRNA 2FGRA 4KR4A 5DL5A 3AAEA 2N2LA 2ZFGA 1MM4A 6PRNA 2GMYA 2XE1A 3LK2A 1THQA 1IZNA 4LSIA 4AYEC 5FVNA 1H6S1 1GFMA 3QRAA 4GCPA 2K0LA 3HWBA 5DIKA 4O4UA 1HXXA 4AYDC 4AZLA 2OUWA 4FZNA 4RJXA 4AYID 2XE2A 5ADXK 4RL9A 2PRRA 1OPFA 2ZLDA 1Q9FA 4FUVA 4GHBA 3VE2A 2M06A 5DL8A 3SY7A 5EE2A 1ZHTA 2PRNA 3TZGA 4Z3TA 3AA6A 2W81C 4FRXA 2FGQX 1LW1A 1Q9GA 5D5DA 2XE3A 1E54A 3GP6A 4FRTA 2KXPB 4LSHA 4O3YA 1GFNA 1ORMA 1HXUA 3VZTX 4FT6A 4JCHA 3AA1A 4KRAA 4RLCA 3O0EA 3PQSA 2XTQA 2KXPA 1ME5A 3V8UA 1BT9A 3QRCA 2KZ7B 1ZHZA 4PUXA 2MHLA 2Y0HA 3PRNA 3HOLA 4O3WA 1ZHXA 4XNKA 3HOEA 4AKRB 3PORA 1KNCA 1GFQA 1BH3A 2W80C 2ERVA 5DL6A 2O4DA 2YNKA 4FESA 4O3ZA 1QJPA 2Y2XA 3DA4A 3JTYA 2Y0KA 4AKMA 3C5OA 4O3XB 4G9QA 2OMFA 2JN8A 1BXWA 2N2MA 2KZ7A 4U9CA 4AYMC 5JDPA 4G76A 3POQA 4B61A 1IZNB 1PRNA 1ZHYA 3G7GA 3SZVA 3SYBA 3PQUA 3LVYA 4E1TA 7PRNA 4RLBA 3AA6B 3VY8X 3AA1B 1ZHWA 3AAEB 5PRNA 3D7IA 4BUMX 3BEYA 1GFOA 1P4TA 1PHOA 2CWQA 5DIPA 3LK42 4FZLA 4GCQA 3SY9A 1OSMA 3NSGA 3LK3A 3POXA 3K19A 3RBHA 4D64A 4GF4A 2J1NA 2O4VA 4FSOA 3WI4A 3LK2B 3FYXA 3C1LA 3VY9X 2KDYA 4JFBA 5T5FA 4GCSA 3UAQA 1GFPA 1HXTA 3VE1A 4AKRA 3SYSA 4QQ1A 4LSFA 3UPGA 2ES9A 2Y0LA 2GE4A 2XMXA 4RJWA 5ADXL 5AFUK 2LFUA 3T24A 2F1VA 2ODJA 2J4UP 3AAAB 3AAAA 4F4BA 3LK41 4D65A 2QTKA 3T20A 4XNLA 4LSEA 5AFUL 4FOZA 2M07A 2LHFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LK4 2;  2KXP A;  3LK2 A;  2KZ7 B;  3AA7 B;  3LK3 A;  1IZN A;  4AKR B;  3AA0 A;  3LK2 B;  5ADX K;  3AA0 B;  4AKR A;  5ADX L;  3AA6 A;  2KZ7 A;  3AA7 A;  5AFU K;  1IZN B;  3LK3 B;  3AAA B;  3AAA A;  3LK4 1;  2KXP B;  3AA6 B;  5AFU L;  3AA1 B;  3AAE A;  3AAE B;  3AA1 A; 
#chains in the Genus database with same CATH topology
 1MPF A;  1S5L O;  2POR A;  4UB6 O;  2X27 X;  2WJR A;  4E1S A;  2PFX A;  2KC0 A;  5GTH O;  1P8C A;  5G38 A;  4O4X A;  2XE5 A;  3AA7 B;  3KVD D;  1QJ9 A;  2F1T A;  2XG6 A;  2R8A A;  4N58 A;  2YPV A;  3WI5 A;  4FSP A;  4FMS A;  4K3B A;  2MNH A;  5IYU A;  1MM5 A;  5GV0 A;  3AA0 A;  2K4T A;  3DA3 A;  4FZM A;  5KAF O;  4PR7 A;  4AFK A;  4IL6 O;  1G90 A;  3AA0 B;  4O49 A;  3VZU X;  5G26 A;  4D5U A;  4G75 A;  4KR8 A;  3HW9 A;  2IJC A;  1VKE A;  4AYN A;  3UU2 A;  3SZD A;  3AA7 A;  3A2S X;  2OYO A;  4N59 A;  3LK3 B;  2AF7 A;  1YS5 A;  2R4N A;  3PGR A;  3A0H O;  2QEU A;  2Q0T A;  3EMN X;  5DL7 A;  2Y7S A;  3VZW X;  4AUI A;  4C69 X;  3T0S A;  1GU9 A;  1QJ8 A;  2XTR A;  2JMM A;  3POU A;  8PRN A;  3KZI O;  2FGR A;  4KR4 A;  4N74 A;  3AAE A;  2N2L A;  2ZFG A;  1MM4 A;  5DL5 A;  6PRN A;  2GMY A;  2WVP A;  3PGU A;  4UB8 O;  3WU2 O;  5G3A A;  2XE1 A;  2IWV A;  3LK2 A;  1THQ A;  1IZN A;  4LSI A;  5H2F O;  4AYE C;  5FVN A;  1H6S 1;  1GFM A;  3QRA A;  4GCP A;  2K0L A;  3HWB A;  5DIK A;  4O4U A;  1HXX A;  4AYD C;  1T16 A;  4AZL A;  2OUW A;  2F1C X;  4FZN A;  4RJX A;  4AYI D;  2XE2 A;  5ADX K;  4RL9 A;  2PRR A;  1OPF A;  2ZLD A;  1Q9F A;  2WJQ A;  4FUV A;  4GHB A;  2M06 A;  5DL8 A;  1T1L A;  5EE2 A;  1ZHT A;  2PRN A;  3SY7 A;  3TZG A;  3VE2 A;  4Z3T A;  3AA6 A;  2W81 C;  4FRX A;  1LW1 A;  1Q9G A;  2FGQ X;  5D5D A;  2XE3 A;  1E54 A;  3GP6 A;  4FRT A;  2KXP B;  4LSH A;  3JCU O;  1GFN A;  1ORM A;  1HXU A;  4O3Y A;  3VZT X;  2IWW A;  4FT6 A;  2R4P A;  4JCH A;  3AA1 A;  4KRA A;  4RLC A;  3O0E A;  3BS0 A;  3PQS A;  2XTQ A;  2KXP A;  2R4L A;  1ME5 A;  3V8U A;  1BT9 A;  3QRC A;  2KZ7 B;  1ZHZ A;  4PUX A;  2MHL A;  2Y0H A;  3PRN A;  3HOL A;  4O3W A;  1ZHX A;  4XNK A;  3HOE A;  4AKR B;  5TIS O;  3POR A;  1KNC A;  3PGS A;  1GFQ A;  1BH3 A;  2W80 C;  2ERV A;  3DZM A;  5DL6 A;  2O4D A;  2YNK A;  4FES A;  4N75 A;  1QJP A;  2Y2X A;  3DA4 A;  3JTY A;  2Y0K A;  4O3Z A;  3C5O A;  4AKM A;  4O3X B;  4G9Q A;  2OMF A;  2JN8 A;  1BXW A;  2N2M A;  2KZ7 A;  4U9C A;  5E79 O;  4AYM C;  5JDP A;  4G76 A;  3POQ A;  4B61 A;  1IZN B;  1PRN A;  1ZHY A;  3G7G A;  3SZV A;  3SYB A;  3PQU A;  3LVY A;  4E1T A;  7PRN A;  4RLB A;  3AA6 B;  3VY8 X;  2R89 A;  3AA1 B;  3BRY A;  4CTD A;  1ZHW A;  3AAE B;  5G39 A;  5GTI O;  5PRN A;  3D7I A;  3A0B O;  3BEY A;  4BUM X;  1GFO A;  5KAI O;  1P4T A;  3DWO X;  1PHO A;  2CWQ A;  5DIP A;  3LK4 2;  4FZL A;  4GCQ A;  3SY9 A;  1OSM A;  3NSG A;  5B5E O;  3LK3 A;  3POX A;  3K19 A;  3RBH A;  4D64 A;  4GF4 A;  2J1N A;  2O4V A;  4FSO A;  5B66 O;  4C00 A;  2R4O A;  3NJT A;  3WI4 A;  3LK2 B;  3FYX A;  3C1L A;  3VY9 X;  2KDY A;  4JFB A;  5T5F A;  4GCS A;  3UAQ A;  1GFP A;  1HXT A;  3BRZ A;  4AKR A;  3SYS A;  3VE1 A;  4PJ0 O;  4LSF A;  4QQ1 A;  2ES9 A;  2Y0L A;  3UPG A;  2GE4 A;  2XMX A;  2R88 A;  4K3C A;  2X9K A;  4RJW A;  5AFU K;  4C4V B;  3PF1 A;  5ADX L;  2LFU A;  3T24 A;  2F1V A;  2ODJ A;  2J4U P;  3AAA B;  3AAA A;  4F4B A;  3LK4 1;  4D65 A;  3DWN A;  2QTK A;  3T20 A;  4XNL A;  4FQE A;  4LSE A;  4C4V A;  5AFU L;  4FOZ A;  2M07 A;  2LHF A;  2AXT O;  2JQY A; 
#chains in the Genus database with same CATH homology
 1MPF A;  2POR A;  2X27 X;  4E1S A;  2PFX A;  2KC0 A;  1P8C A;  4O4X A;  2XE5 A;  3AA7 B;  3KVD D;  1QJ9 A;  2F1T A;  2XG6 A;  4N58 A;  3WI5 A;  2YPV A;  5IYU A;  4FSP A;  4FMS A;  2MNH A;  1MM5 A;  5GV0 A;  3AA0 A;  2K4T A;  3DA3 A;  4FZM A;  4AFK A;  1G90 A;  3AA0 B;  4O49 A;  3VZU X;  5G26 A;  4D5U A;  4G75 A;  4KR8 A;  3HW9 A;  2IJC A;  1VKE A;  4AYN A;  3UU2 A;  3SZD A;  3AA7 A;  3A2S X;  2OYO A;  4N59 A;  3LK3 B;  2AF7 A;  1YS5 A;  4C69 X;  2QEU A;  2Q0T A;  3EMN X;  5DL7 A;  2Y7S A;  3VZW X;  4AUI A;  3T0S A;  1GU9 A;  1QJ8 A;  2XTR A;  2JMM A;  3POU A;  8PRN A;  2FGR A;  4KR4 A;  5DL5 A;  3AAE A;  2N2L A;  2ZFG A;  1MM4 A;  6PRN A;  2GMY A;  2XE1 A;  3LK2 A;  1THQ A;  1IZN A;  4LSI A;  4AYE C;  5FVN A;  1H6S 1;  1GFM A;  3QRA A;  4GCP A;  2K0L A;  3HWB A;  5DIK A;  4O4U A;  1HXX A;  4AYD C;  4AZL A;  2OUW A;  4FZN A;  4RJX A;  4AYI D;  2XE2 A;  5ADX K;  4RL9 A;  2PRR A;  1OPF A;  2ZLD A;  1Q9F A;  4FUV A;  4GHB A;  3VE2 A;  2M06 A;  5DL8 A;  3SY7 A;  5EE2 A;  1ZHT A;  2PRN A;  3TZG A;  4Z3T A;  3AA6 A;  2W81 C;  4FRX A;  2FGQ X;  1LW1 A;  1Q9G A;  5D5D A;  2XE3 A;  1E54 A;  3GP6 A;  4FRT A;  2KXP B;  4LSH A;  4O3Y A;  1GFN A;  1ORM A;  1HXU A;  3VZT X;  4FT6 A;  4JCH A;  3AA1 A;  4KRA A;  4RLC A;  3O0E A;  3PQS A;  2XTQ A;  2KXP A;  1ME5 A;  3V8U A;  1BT9 A;  3QRC A;  2KZ7 B;  1ZHZ A;  4PUX A;  2MHL A;  2Y0H A;  3PRN A;  3HOL A;  4O3W A;  1ZHX A;  4XNK A;  3HOE A;  4AKR B;  3POR A;  1KNC A;  1GFQ A;  1BH3 A;  2W80 C;  2ERV A;  5DL6 A;  2O4D A;  2YNK A;  4FES A;  4O3Z A;  1QJP A;  2Y2X A;  3DA4 A;  3JTY A;  2Y0K A;  4AKM A;  3C5O A;  4O3X B;  4G9Q A;  2OMF A;  2JN8 A;  1BXW A;  2N2M A;  2KZ7 A;  4U9C A;  4AYM C;  5JDP A;  4G76 A;  3POQ A;  4B61 A;  1IZN B;  1PRN A;  1ZHY A;  3G7G A;  3SZV A;  3SYB A;  3PQU A;  3LVY A;  4E1T A;  7PRN A;  4RLB A;  3AA6 B;  3VY8 X;  3AA1 B;  1ZHW A;  3AAE B;  5PRN A;  3D7I A;  4BUM X;  3BEY A;  1GFO A;  1P4T A;  1PHO A;  2CWQ A;  5DIP A;  3LK4 2;  4FZL A;  4GCQ A;  3SY9 A;  1OSM A;  3NSG A;  3LK3 A;  3POX A;  3K19 A;  3RBH A;  4D64 A;  4GF4 A;  2J1N A;  2O4V A;  4FSO A;  3WI4 A;  3LK2 B;  3FYX A;  3C1L A;  3VY9 X;  2KDY A;  4JFB A;  5T5F A;  4GCS A;  3UAQ A;  1GFP A;  1HXT A;  3VE1 A;  4AKR A;  3SYS A;  4QQ1 A;  4LSF A;  3UPG A;  2ES9 A;  2Y0L A;  2GE4 A;  2XMX A;  4RJW A;  5ADX L;  5AFU K;  2LFU A;  3T24 A;  2F1V A;  2ODJ A;  2J4U P;  3AAA B;  3AAA A;  4F4B A;  3LK4 1;  4D65 A;  2QTK A;  3T20 A;  4XNL A;  4LSE A;  5AFU L;  4FOZ A;  2M07 A;  2LHF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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