1IZNA

Crystal structure of actin filament capping protein capz
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
275
structure length
275
Chain Sequence
RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYDDQVLITEHGDLGNGRFLDPRNKISFKFDHLRKEASDPQPEDTESALKQWRDACDSALRAYVKDHYPNGFCTVYGKSIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVAAVLKIQVHYYEDGNVQLVSHKDIQDSVQVSSDVQTAKEFIKIIENAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of CapZ: structural basis for actin filament barbed end capping
pubmed doi rcsb
source organism Gallus gallus
molecule tags Protein binding
molecule keywords CapZ alpha-1 subunit
total genus 72
structure length 275
sequence length 275
chains with identical sequence C
ec nomenclature
pdb deposition date 2002-10-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01267 F-actin_cap_A F-actin capping protein alpha subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 1iznA01
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 1iznA02
3LK41 3AA7B 3LK3A 3LK3B 3LK2B 5AFUL 5AFUK 5ADXK 3AAAA 3AA0A 3AA1A 3AAEB 3AA6A 4AKRB 3AA7A 1IZNA 4AKRA 3LK42 3LK2A 3AA0B 2KZ7B 3AAAB 2KZ7A 3AA6B 2KXPA 5ADXL 3AAEA 3AA1B 2KXPB 1IZNB
chains in the Genus database with same CATH superfamily
7PRNA 5H2FO 2IWWA 3AA7B 3A0BO 4C00A 3SZVA 2AXTO 1T1LA 2Y0HA 4U9CA 5TISO 5DL6A 1ZHYA 4KR4A 4PJ0O 2K0LA 3A2SX 3RBHA 3VE1A 3UPGA 5GTHO 3AA0A 2MNHA 2J1NA 3WI4A 4FSOA 4LSFA 1THQA 1KNCA 1PRNA 2FGRA 2QTKA 2R88A 2XMXA 2K4TA 3DWOX 5T5FA 2WJRA 1T16A 3T0SA 4D65A 4XNKA 4FT6A 2XE5A 3FYXA 4O3XB 4O49A 1GFMA 1HXXA 1HXUA 1ZHZA 2KC0A 4AKMA 4B61A 5GV0A 4K3BA 3SYSA 4UB6O 4D5UA 1E54A 2XE3A 4G76A 1MM4A 3AAAB 4E1TA 2LHFA 4LSEA 1G90A 5ADXL 3SYBA 4CTDA 1S5LO 4AYMC 8PRNA 2AF7A 1ORMA 2GE4A 4RJWA 4LSIA 4PUXA 3QRCA 2MHLA 4G75A 5G26A 3C5OA 2XG6A 1ZHTA 1H6S1 4XNLA 3UU2A 2F1VA 2GMYA 2W81C 2XE1A 2YNKA 2JN8A 3PORA 5ADXK 4GCPA 5DL7A 3SY9A 4C4VA 2X9KA 3SY7A 5FVNA 3VZWX 3EMNX 1Q9FA 2M07A 3KZIO 4N59A 6PRNA 3AA1A 1BXWA 3PGSA 2F1TA 3PGUA 3AAEB 3T24A 2IJCA 2PORA 2Q0TA 4G9QA 1P4TA 2XTQA 3JCUO 4AKRB 3AA7A 2WJQA 1IZNA 5DL8A 3BRZA 3VE2A 1GFQA 2R4LA 4RLBA 3K19A 3NSGA 3LK42 2R89A 1Q9GA 3KVDD 3AA0B 4O3YA 5GTIO 5EE2A 2R8AA 4F4BA 1OSMA 1YS5A 2Y2XA 5KAIO 3AA6B 4FRXA 4D64A 3O0EA 2WVPA 1PHOA 3HWBA 4GCQA 2JQYA 1GFOA 3WU2O 4FRTA 2FGQX 1OPFA 4FZMA 3LVYA 5E79O 4C69X 2OUWA 3LK41 4O3WA 3T20A 4FESA 2R4OA 4N58A 5B5EO 3LK3A 1QJ8A 2R4NA 1P8CA 4AZLA 5AFUL 5AFUK 1GFNA 3NJTA 2ES9A 3C1LA 2O4VA 1QJ9A 3TZGA 2W80C 5JDPA 3PQSA 3DWNA 4FUVA 1GU9A 1MM5A 3VY9X 2J4UP 4GHBA 5IYUA 2N2MA 2ERVA 2OMFA 4JCHA 4GF4A 3DA4A 4AYNA 4O4UA 4QQ1A 4AKRA 3POUA 3GP6A 3BEYA 3DA3A 4KR8A 4PR7A 4RLCA 5PRNA 4BUMX 3LK2A 4C4VB 2PRNA 3HW9A 4AYDC 5D5DA 3HOEA 1HXTA 3A0HO 4FQEA 4FZLA 3HOLA 2Y0LA 3PGRA 3VZTX 4E1SA 2YPVA 2F1CX 4AYEC 5DIKA 5G39A 1GFPA 3AA1B 2N2LA 2ZLDA 4IL6O 2XTRA 3VY8X 1ME5A 4LSHA 4GCSA 4RJXA 5G38A 4N75A 2JMMA 2M06A 4AUIA 3LK3B 4FMSA 1BT9A 3LK2B 2O4DA 4JFBA 4KRAA 3VZUX 4N74A 3BS0A 2XE2A 3JTYA 3AAAA 2PRRA 4AYID 2ZFGA 2LFUA 4O4XA 4RL9A 4UB8O 3UAQA 3V8UA 3AA6A 4Z3TA 4FSPA 4K3CA 3WI5A 3POQA 4FZNA 1VKEA 2QEUA 2CWQA 5DIPA 2Y0KA 3DZMA 2KDYA 3G7GA 1BH3A 3POXA 5G3AA 4AFKA 2R4PA 1ZHXA 2IWVA 2KZ7B 3BRYA 1LW1A 2OYOA 3PF1A 2PFXA 1MPFA 2KZ7A 5B66O 2X27X 2ODJA 2KXPA 1ZHWA 3QRAA 3AAEA 1QJPA 5DL5A 4FOZA 5KAFO 3PRNA 4O3ZA 2KXPB 2Y7SA 3D7IA 3PQUA 3SZDA 1IZNB
chains in the Genus database with same CATH topology
7PRNA 3AA7B 3SZVA 2Y0HA 4U9CA 5DL6A 1ZHYA 4KR4A 2K0LA 3A2SX 3RBHA 3VE1A 3UPGA 3AA0A 2MNHA 2J1NA 3WI4A 4FSOA 4LSFA 1THQA 1KNCA 1PRNA 2FGRA 2QTKA 2XMXA 2K4TA 5T5FA 3T0SA 4D65A 4XNKA 4FT6A 2XE5A 3FYXA 4O3XB 4O49A 1GFMA 1HXXA 1HXUA 1ZHZA 2KC0A 4AKMA 4B61A 5GV0A 3SYSA 4D5UA 1E54A 2XE3A 4G76A 1MM4A 3AAAB 4E1TA 2LHFA 4LSEA 1G90A 5ADXL 3SYBA 4AYMC 8PRNA 2AF7A 1ORMA 2GE4A 4RJWA 4LSIA 4PUXA 3QRCA 2MHLA 4G75A 5G26A 3C5OA 2XG6A 1ZHTA 1H6S1 4XNLA 3UU2A 2F1VA 2GMYA 2W81C 2XE1A 2YNKA 2JN8A 3PORA 5ADXK 4GCPA 5DL7A 3SY9A 3SY7A 5FVNA 3VZWX 3EMNX 1Q9FA 2M07A 4N59A 6PRNA 3AA1A 1BXWA 3T24A 2F1TA 3VY9X 3AAEB 2IJCA 2PORA 2Q0TA 4G9QA 1P4TA 2XTQA 4AKRB 3AA7A 1IZNA 5DL8A 3VE2A 1GFQA 4RLBA 3K19A 3NSGA 3LK42 1Q9GA 3KVDD 3AA0B 4O3YA 5EE2A 1OSMA 1YS5A 2Y2XA 3AA6B 4FRXA 4D64A 3O0EA 1PHOA 3HWBA 4GCQA 1GFOA 4FRTA 2FGQX 1OPFA 4FZMA 3LVYA 4C69X 2OUWA 3LK41 4O3WA 3T20A 4FESA 4N58A 3LK3A 1QJ8A 1P8CA 4AZLA 5AFUL 5AFUK 1GFNA 3TZGA 2ES9A 3C1LA 2O4VA 1QJ9A 5JDPA 2W80C 3PQSA 4FUVA 1GU9A 1MM5A 2J4UP 4GHBA 5IYUA 2N2MA 2ERVA 2OMFA 4JCHA 4GF4A 3DA4A 4AYNA 4O4UA 4QQ1A 4AKRA 3POUA 3GP6A 3BEYA 3DA3A 4KR8A 4RLCA 4BUMX 5PRNA 4F4BA 3LK2A 2PRNA 3HW9A 4AYDC 5D5DA 3HOEA 1HXTA 4FZLA 3HOLA 2Y0LA 3VZTX 4E1SA 2YPVA 4AYEC 5DIKA 1GFPA 3AA1B 2N2LA 2ZLDA 2XTRA 3VY8X 1ME5A 4LSHA 4GCSA 4RJXA 2JMMA 2M06A 4AUIA 3LK3B 4FMSA 1BT9A 3LK2B 2O4DA 4JFBA 4KRAA 3VZUX 2XE2A 3JTYA 3AAAA 2PRRA 4AYID 2ZFGA 2LFUA 4O4XA 4RL9A 3UAQA 3V8UA 3AA6A 4Z3TA 4FSPA 3WI5A 3POQA 4FZNA 1VKEA 2QEUA 2CWQA 5DIPA 2Y0KA 2KDYA 3G7GA 1BH3A 3POXA 4AFKA 1ZHXA 2KZ7B 1LW1A 2OYOA 2PFXA 1MPFA 2KZ7A 2X27X 2ODJA 2KXPA 1ZHWA 3QRAA 3AAEA 1QJPA 5DL5A 4FOZA 3PRNA 4O3ZA 2KXPB 2Y7SA 3D7IA 3PQUA 3SZDA 1IZNB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LK4 1;  3AA7 B;  3LK3 A;  3LK3 B;  3LK2 B;  5AFU L;  5AFU K;  5ADX K;  3AAA A;  3AA0 A;  3AA1 A;  3AAE B;  3AA6 A;  4AKR B;  3AA7 A;  1IZN A;  4AKR A;  3LK4 2;  3LK2 A;  3AA0 B;  2KZ7 B;  3AAA B;  2KZ7 A;  3AA6 B;  2KXP A;  5ADX L;  3AAE A;  3AA1 B;  2KXP B;  1IZN B; 
#chains in the Genus database with same CATH topology
 7PRN A;  5H2F O;  2IWW A;  3AA7 B;  3A0B O;  4C00 A;  3SZV A;  2AXT O;  1T1L A;  2Y0H A;  4U9C A;  5TIS O;  5DL6 A;  1ZHY A;  4KR4 A;  4PJ0 O;  2K0L A;  3A2S X;  3RBH A;  3VE1 A;  3UPG A;  5GTH O;  3AA0 A;  2MNH A;  2J1N A;  3WI4 A;  4FSO A;  4LSF A;  1THQ A;  1KNC A;  1PRN A;  2FGR A;  2QTK A;  2R88 A;  2XMX A;  2K4T A;  3DWO X;  5T5F A;  2WJR A;  1T16 A;  3T0S A;  4D65 A;  4XNK A;  4FT6 A;  2XE5 A;  3FYX A;  4O3X B;  4O49 A;  1GFM A;  1HXX A;  1HXU A;  1ZHZ A;  2KC0 A;  4AKM A;  4B61 A;  5GV0 A;  4K3B A;  3SYS A;  4UB6 O;  4D5U A;  1E54 A;  2XE3 A;  4G76 A;  1MM4 A;  3AAA B;  4E1T A;  2LHF A;  4LSE A;  1G90 A;  5ADX L;  3SYB A;  4CTD A;  1S5L O;  4AYM C;  8PRN A;  2AF7 A;  1ORM A;  2GE4 A;  4RJW A;  4LSI A;  4PUX A;  3QRC A;  2MHL A;  4G75 A;  5G26 A;  3C5O A;  2XG6 A;  1ZHT A;  1H6S 1;  4XNL A;  3UU2 A;  2F1V A;  2GMY A;  2W81 C;  2XE1 A;  2YNK A;  2JN8 A;  3POR A;  5ADX K;  4GCP A;  5DL7 A;  3SY9 A;  4C4V A;  2X9K A;  3SY7 A;  5FVN A;  3VZW X;  3EMN X;  1Q9F A;  2M07 A;  3KZI O;  4N59 A;  6PRN A;  3AA1 A;  1BXW A;  3PGS A;  2F1T A;  3PGU A;  3AAE B;  3T24 A;  2IJC A;  2POR A;  2Q0T A;  4G9Q A;  1P4T A;  2XTQ A;  3JCU O;  4AKR B;  3AA7 A;  2WJQ A;  1IZN A;  5DL8 A;  3BRZ A;  3VE2 A;  1GFQ A;  2R4L A;  4RLB A;  3K19 A;  3NSG A;  3LK4 2;  2R89 A;  1Q9G A;  3KVD D;  3AA0 B;  4O3Y A;  5GTI O;  5EE2 A;  2R8A A;  4F4B A;  1OSM A;  1YS5 A;  2Y2X A;  5KAI O;  3AA6 B;  4FRX A;  4D64 A;  3O0E A;  2WVP A;  1PHO A;  3HWB A;  4GCQ A;  2JQY A;  1GFO A;  3WU2 O;  4FRT A;  2FGQ X;  1OPF A;  4FZM A;  3LVY A;  5E79 O;  4C69 X;  2OUW A;  3LK4 1;  4O3W A;  3T20 A;  4FES A;  2R4O A;  4N58 A;  5B5E O;  3LK3 A;  1QJ8 A;  2R4N A;  1P8C A;  4AZL A;  5AFU L;  5AFU K;  1GFN A;  3NJT A;  2ES9 A;  3C1L A;  2O4V A;  1QJ9 A;  3TZG A;  2W80 C;  5JDP A;  3PQS A;  3DWN A;  4FUV A;  1GU9 A;  1MM5 A;  3VY9 X;  2J4U P;  4GHB A;  5IYU A;  2N2M A;  2ERV A;  2OMF A;  4JCH A;  4GF4 A;  3DA4 A;  4AYN A;  4O4U A;  4QQ1 A;  4AKR A;  3POU A;  3GP6 A;  3BEY A;  3DA3 A;  4KR8 A;  4PR7 A;  4RLC A;  5PRN A;  4BUM X;  3LK2 A;  4C4V B;  2PRN A;  3HW9 A;  4AYD C;  5D5D A;  3HOE A;  1HXT A;  3A0H O;  4FQE A;  4FZL A;  3HOL A;  2Y0L A;  3PGR A;  3VZT X;  4E1S A;  2YPV A;  2F1C X;  4AYE C;  5DIK A;  5G39 A;  1GFP A;  3AA1 B;  2N2L A;  2ZLD A;  4IL6 O;  2XTR A;  3VY8 X;  1ME5 A;  4LSH A;  4GCS A;  4RJX A;  5G38 A;  4N75 A;  2JMM A;  2M06 A;  4AUI A;  3LK3 B;  4FMS A;  1BT9 A;  3LK2 B;  2O4D A;  4JFB A;  4KRA A;  3VZU X;  4N74 A;  3BS0 A;  2XE2 A;  3JTY A;  3AAA A;  2PRR A;  4AYI D;  2ZFG A;  2LFU A;  4O4X A;  4RL9 A;  4UB8 O;  3UAQ A;  3V8U A;  3AA6 A;  4Z3T A;  4FSP A;  4K3C A;  3WI5 A;  3POQ A;  4FZN A;  1VKE A;  2QEU A;  2CWQ A;  5DIP A;  2Y0K A;  3DZM A;  2KDY A;  3G7G A;  1BH3 A;  3POX A;  5G3A A;  4AFK A;  2R4P A;  1ZHX A;  2IWV A;  2KZ7 B;  3BRY A;  1LW1 A;  2OYO A;  3PF1 A;  2PFX A;  1MPF A;  2KZ7 A;  5B66 O;  2X27 X;  2ODJ A;  2KXP A;  1ZHW A;  3QRA A;  3AAE A;  1QJP A;  5DL5 A;  4FOZ A;  5KAF O;  3PRN A;  4O3Z A;  2KXP B;  2Y7S A;  3D7I A;  3PQU A;  3SZD A;  1IZN B; 
#chains in the Genus database with same CATH homology
 7PRN A;  3AA7 B;  3SZV A;  2Y0H A;  4U9C A;  5DL6 A;  1ZHY A;  4KR4 A;  2K0L A;  3A2S X;  3RBH A;  3VE1 A;  3UPG A;  3AA0 A;  2MNH A;  2J1N A;  3WI4 A;  4FSO A;  4LSF A;  1THQ A;  1KNC A;  1PRN A;  2FGR A;  2QTK A;  2XMX A;  2K4T A;  5T5F A;  3T0S A;  4D65 A;  4XNK A;  4FT6 A;  2XE5 A;  3FYX A;  4O3X B;  4O49 A;  1GFM A;  1HXX A;  1HXU A;  1ZHZ A;  2KC0 A;  4AKM A;  4B61 A;  5GV0 A;  3SYS A;  4D5U A;  1E54 A;  2XE3 A;  4G76 A;  1MM4 A;  3AAA B;  4E1T A;  2LHF A;  4LSE A;  1G90 A;  5ADX L;  3SYB A;  4AYM C;  8PRN A;  2AF7 A;  1ORM A;  2GE4 A;  4RJW A;  4LSI A;  4PUX A;  3QRC A;  2MHL A;  4G75 A;  5G26 A;  3C5O A;  2XG6 A;  1ZHT A;  1H6S 1;  4XNL A;  3UU2 A;  2F1V A;  2GMY A;  2W81 C;  2XE1 A;  2YNK A;  2JN8 A;  3POR A;  5ADX K;  4GCP A;  5DL7 A;  3SY9 A;  3SY7 A;  5FVN A;  3VZW X;  3EMN X;  1Q9F A;  2M07 A;  4N59 A;  6PRN A;  3AA1 A;  1BXW A;  3T24 A;  2F1T A;  3VY9 X;  3AAE B;  2IJC A;  2POR A;  2Q0T A;  4G9Q A;  1P4T A;  2XTQ A;  4AKR B;  3AA7 A;  1IZN A;  5DL8 A;  3VE2 A;  1GFQ A;  4RLB A;  3K19 A;  3NSG A;  3LK4 2;  1Q9G A;  3KVD D;  3AA0 B;  4O3Y A;  5EE2 A;  1OSM A;  1YS5 A;  2Y2X A;  3AA6 B;  4FRX A;  4D64 A;  3O0E A;  1PHO A;  3HWB A;  4GCQ A;  1GFO A;  4FRT A;  2FGQ X;  1OPF A;  4FZM A;  3LVY A;  4C69 X;  2OUW A;  3LK4 1;  4O3W A;  3T20 A;  4FES A;  4N58 A;  3LK3 A;  1QJ8 A;  1P8C A;  4AZL A;  5AFU L;  5AFU K;  1GFN A;  3TZG A;  2ES9 A;  3C1L A;  2O4V A;  1QJ9 A;  5JDP A;  2W80 C;  3PQS A;  4FUV A;  1GU9 A;  1MM5 A;  2J4U P;  4GHB A;  5IYU A;  2N2M A;  2ERV A;  2OMF A;  4JCH A;  4GF4 A;  3DA4 A;  4AYN A;  4O4U A;  4QQ1 A;  4AKR A;  3POU A;  3GP6 A;  3BEY A;  3DA3 A;  4KR8 A;  4RLC A;  4BUM X;  5PRN A;  4F4B A;  3LK2 A;  2PRN A;  3HW9 A;  4AYD C;  5D5D A;  3HOE A;  1HXT A;  4FZL A;  3HOL A;  2Y0L A;  3VZT X;  4E1S A;  2YPV A;  4AYE C;  5DIK A;  1GFP A;  3AA1 B;  2N2L A;  2ZLD A;  2XTR A;  3VY8 X;  1ME5 A;  4LSH A;  4GCS A;  4RJX A;  2JMM A;  2M06 A;  4AUI A;  3LK3 B;  4FMS A;  1BT9 A;  3LK2 B;  2O4D A;  4JFB A;  4KRA A;  3VZU X;  2XE2 A;  3JTY A;  3AAA A;  2PRR A;  4AYI D;  2ZFG A;  2LFU A;  4O4X A;  4RL9 A;  3UAQ A;  3V8U A;  3AA6 A;  4Z3T A;  4FSP A;  3WI5 A;  3POQ A;  4FZN A;  1VKE A;  2QEU A;  2CWQ A;  5DIP A;  2Y0K A;  2KDY A;  3G7G A;  1BH3 A;  3POX A;  4AFK A;  1ZHX A;  2KZ7 B;  1LW1 A;  2OYO A;  2PFX A;  1MPF A;  2KZ7 A;  2X27 X;  2ODJ A;  2KXP A;  1ZHW A;  3QRA A;  3AAE A;  1QJP A;  5DL5 A;  4FOZ A;  3PRN A;  4O3Z A;  2KXP B;  2Y7S A;  3D7I A;  3PQU A;  3SZD A;  1IZN B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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