3AA6A

Crystal structure of actin capping protein in complex with the cp-binding motif derived from cd2ap
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
270
structure length
270
Chain Sequence
RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYDDQVLITEHGDLGNGRFLDPRNKISFKFDHLRKEASDPQPEDTESALKQWRDACDSALRAYVKDHYPNGFCTVYGKSIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVAAVLKIQVHYYEDGNVQLVSHKDIQDSVQVSSDVQTAKEFIKIIENAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords F-actin-capping protein subunit alpha-1
publication title Two distinct mechanisms for actin capping protein regulation--steric and allosteric inhibition
pubmed doi rcsb
source organism Gallus gallus
molecule tags Protein binding
total genus 87
structure length 270
sequence length 270
ec nomenclature
pdb deposition date 2009-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01267 F-actin_cap_A F-actin capping protein alpha subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 3aa6A01
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 3aa6A02
3AA6B 1IZNA 3LK3B 3AA7A 2KZ7B 4AKRB 3LK2B 3LK41 3AAEA 1IZNB 3AA7B 2KXPA 5ADXL 3AA1A 3LK42 3AA0A 3AAEB 3AAAA 5ADXK 5AFUL 2KXPB 3AA6A 3AA1B 3LK3A 3AA0B 2KZ7A 4AKRA 3AAAB 3LK2A 5AFUK
chains in the Genus database with same CATH superfamily
1ME5A 5GV0A 3T20A 2F1CX 4G75A 4FUVA 3A0BO 3A0HO 2ODJA 5IYUA 3AA1A 5FVNA 5ADXK 2Y0LA 5AFUL 4GCPA 3VY9X 4E1TA 2F1VA 2PFXA 2WVPA 2XTRA 3AA6B 2KC0A 3DZMA 3HW9A 4FRTA 3VY8X 1P4TA 2W81C 4O3ZA 2OMFA 3SZVA 2Q0TA 3G7GA 4FMSA 1ZHWA 2K4TA 5TISO 4XNLA 2FGRA 2KDYA 4AYDC 4E1SA 3HOLA 4G76A 5DL8A 2LHFA 3LK3A 4RJWA 1MPFA 2IWVA 6PRNA 2WJQA 4GCSA 5B66O 2M06A 4LSHA 1ZHZA 4C4VA 4KR4A 3AA0A 4O4XA 5JDPA 4JCHA 3KVDD 1QJ9A 5D5DA 3DA3A 2R89A 4AFKA 4B61A 5DL5A 3AA7A 1BT9A 2ERVA 4QQ1A 2Y7SA 2AF7A 5B5EO 1THQA 4AYEC 3WU2O 2MNHA 2QEUA 2ZLDA 3PQUA 2KXPB 3NSGA 4FSPA 1Q9FA 2R4NA 5G39A 4LSIA 3A2SX 4O3YA 3JCUO 4FZLA 5GTIO 2W80C 1IZNA 4D64A 1T1LA 3WI5A 3T24A 3T0SA 1GU9A 3UPGA 2R4PA 3AA1B 1P8CA 1OPFA 2WJRA 3VE2A 3WI4A 5DIKA 4JFBA 2R8AA 3DWOX 2OYOA 3EMNX 3QRCA 4N59A 3VZWX 2X27X 2MHLA 2Y0HA 4RLBA 3PORA 1H6S1 3SY7A 3SYSA 4O49A 5G26A 5T5FA 2LFUA 4IL6O 4UB6O 4O3WA 4FRXA 2N2LA 3LK3B 4LSFA 3VZTX 2PRRA 5DIPA 3KZIO 2J1NA 4C00A 3LK42 2O4VA 4C4VB 2XE3A 3C1LA 2K0LA 4Z3TA 2QTKA 2F1TA 2JQYA 3AA0B 2J4UP 2ES9A 4AKRA 5AFUK 2GE4A 4BUMX 3VE1A 1BXWA 4FQEA 5GTHO 3AA7B 3PF1A 4RJXA 4AYMC 4K3CA 2R88A 4FZNA 3C5OA 2N2MA 1PHOA 4LSEA 3PRNA 3AAEA 1IZNB 5KAIO 3K19A 3POUA 2AXTO 4FT6A 8PRNA 4N58A 1GFMA 3RBHA 4AKMA 3BEYA 3DA4A 1HXXA 2Y0KA 3O0EA 1G90A 1S5LO 1YS5A 2IWWA 3NJTA 4PUXA 2X9KA 4FESA 2XG6A 1Q9GA 4KRAA 3POXA 4AUIA 3QRAA 4GCQA 3AAAA 1HXTA 3POQA 3PGUA 3BS0A 5PRNA 2XE2A 4PR7A 1OSMA 3LK2A 4AYID 1GFOA 2R4OA 3LK41 1LW1A 2XMXA 5DL7A 4UB8O 7PRNA 1ZHYA 4XNKA 1ZHXA 5ADXL 2XE1A 5H2FO 2GMYA 4PJ0O 4RLCA 2Y2XA 2OUWA 2KZ7A 3LVYA 2YNKA 4CTDA 4AKRB 4AZLA 4N75A 2YPVA 5G3AA 3HWBA 2PORA 2PRNA 5EE2A 2JMMA 3SY9A 2M07A 2O4DA 3PGSA 5DL6A 2XTQA 3TZGA 1QJ8A 4FZMA 5E79O 4GHBA 3VZUX 1E54A 4U9CA 1T16A 5G38A 1ZHTA 3AAEB 4O4UA 3PGRA 1MM5A 1ORMA 3D7IA 1KNCA 3AA6A 2JN8A 3PQSA 2XE5A 1GFQA 3UU2A 1VKEA 3SYBA 2R4LA 3GP6A 4KR8A 1GFNA 3BRYA 2ZFGA 4FOZA 3SZDA 1BH3A 3AAAB 3UAQA 3LK2B 2IJCA 1QJPA 3DWNA 4RL9A 4C69X 4D5UA 2FGQX 1MM4A 4G9QA 2CWQA 2KZ7B 4F4BA 4GF4A 3FYXA 1GFPA 3HOEA 1HXUA 2KXPA 5KAFO 3V8UA 4D65A 4AYNA 4FSOA 1PRNA 4O3XB 4K3BA 3JTYA 3BRZA 4N74A
chains in the Genus database with same CATH topology
4LSIA 3A2SX 3C5OA 4O3YA 3TZGA 2N2MA 4FZLA 1QJ8A 4FZMA 2W80C 1IZNA 4D64A 1ME5A 1PHOA 5GV0A 4LSEA 4GHBA 3PRNA 3T20A 3VZUX 3AAEA 3WI5A 4G75A 1E54A 1IZNB 4U9CA 3T24A 4FUVA 3K19A 3POUA 3T0SA 2ODJA 5IYUA 1GU9A 4FT6A 8PRNA 4N58A 1GFMA 3RBHA 3AA1A 1ZHTA 3AAEB 4O4UA 5FVNA 5ADXK 2Y0LA 4AKMA 1MM5A 1ORMA 3UPGA 5AFUL 4GCPA 3D7IA 3VY9X 1KNCA 1P8CA 3AA6A 3BEYA 1OPFA 2F1VA 3AA1B 2JN8A 3DA4A 1HXXA 3VE2A 4E1TA 2PFXA 2Y0KA 3PQSA 3WI4A 2XE5A 5DIKA 1GFQA 4JFBA 3UU2A 2XTRA 3O0EA 1G90A 1VKEA 3AA6B 1YS5A 2KC0A 3SYBA 2OYOA 3HW9A 4FRTA 3EMNX 1P4TA 2W81C 3VY8X 3QRCA 4N59A 3VZWX 2X27X 2MHLA 4KR8A 3GP6A 4PUXA 4O3ZA 2Y0HA 1GFNA 4RLBA 2OMFA 3SZVA 4FESA 2Q0TA 1H6S1 1Q9GA 2XG6A 3PORA 4KRAA 3G7GA 4FMSA 3POXA 3SY7A 4AUIA 1ZHWA 3QRAA 2K4TA 3SYSA 2ZFGA 4FOZA 3SZDA 4GCQA 4XNLA 2FGRA 3AAAA 2KDYA 4O49A 4AYDC 4E1SA 3HOLA 5G26A 1HXTA 3POQA 4G76A 5DL8A 5T5FA 5PRNA 2XE2A 2LHFA 3LK3A 2LFUA 4RJWA 1OSMA 1BH3A 3AAAB 3LK2A 4O3WA 4FRXA 1MPFA 2N2LA 4AYID 3UAQA 1GFOA 3LK3B 4LSFA 6PRNA 3LK2B 3LK41 3VZTX 1LW1A 2PRRA 2XMXA 5DL7A 7PRNA 2IJCA 5DIPA 4GCSA 1ZHYA 2M06A 4LSHA 1ZHZA 4XNKA 1ZHXA 5ADXL 2J1NA 4KR4A 2XE1A 1QJPA 3LK42 3AA0A 4O4XA 2GMYA 2O4VA 4RL9A 4JCHA 5JDPA 3KVDD 4C69X 2XE3A 1QJ9A 4RLCA 5D5DA 2Y2XA 4D5UA 3C1LA 2OUWA 2FGQX 2K0LA 3DA3A 4Z3TA 1MM4A 2F1TA 2QTKA 3AA0B 2KZ7A 4AFKA 4B61A 3LVYA 2J4UP 4G9QA 2ES9A 4AKRA 2YNKA 5AFUK 2GE4A 2CWQA 4BUMX 5DL5A 3AA7A 2KZ7B 3VE1A 4F4BA 1BT9A 4AKRB 2ERVA 4GF4A 1BXWA 3FYXA 1GFPA 4QQ1A 4AZLA 2Y7SA 2AF7A 2YPVA 3AA7B 3HOEA 1HXUA 3HWBA 2KXPA 1THQA 2PORA 4RJXA 3V8UA 2PRNA 4AYEC 4AYMC 4D65A 5EE2A 4AYNA 4FSOA 2MNHA 2QEUA 1PRNA 2ZLDA 4O3XB 2JMMA 3JTYA 3PQUA 2KXPB 3SY9A 3NSGA 2M07A 4FSPA 1Q9FA 2O4DA 4FZNA 5DL6A 2XTQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AA6 B;  1IZN A;  3LK3 B;  3AA7 A;  2KZ7 B;  4AKR B;  3LK2 B;  3LK4 1;  3AAE A;  1IZN B;  3AA7 B;  2KXP A;  5ADX L;  3AA1 A;  3LK4 2;  3AA0 A;  3AAE B;  3AAA A;  5ADX K;  5AFU L;  2KXP B;  3AA6 A;  3AA1 B;  3LK3 A;  3AA0 B;  2KZ7 A;  4AKR A;  3AAA B;  3LK2 A;  5AFU K; 
#chains in the Genus database with same CATH topology
 1ME5 A;  5GV0 A;  3T20 A;  2F1C X;  4G75 A;  4FUV A;  3A0B O;  3A0H O;  2ODJ A;  5IYU A;  3AA1 A;  5FVN A;  5ADX K;  2Y0L A;  5AFU L;  4GCP A;  3VY9 X;  4E1T A;  2F1V A;  2PFX A;  2WVP A;  2XTR A;  3AA6 B;  2KC0 A;  3DZM A;  3HW9 A;  4FRT A;  3VY8 X;  1P4T A;  2W81 C;  4O3Z A;  2OMF A;  3SZV A;  2Q0T A;  3G7G A;  4FMS A;  1ZHW A;  2K4T A;  5TIS O;  4XNL A;  2FGR A;  2KDY A;  4AYD C;  4E1S A;  3HOL A;  4G76 A;  5DL8 A;  2LHF A;  3LK3 A;  4RJW A;  1MPF A;  2IWV A;  6PRN A;  2WJQ A;  4GCS A;  5B66 O;  2M06 A;  4LSH A;  1ZHZ A;  4C4V A;  4KR4 A;  3AA0 A;  4O4X A;  5JDP A;  4JCH A;  3KVD D;  1QJ9 A;  5D5D A;  3DA3 A;  2R89 A;  4AFK A;  4B61 A;  5DL5 A;  3AA7 A;  1BT9 A;  2ERV A;  4QQ1 A;  2Y7S A;  2AF7 A;  5B5E O;  1THQ A;  4AYE C;  3WU2 O;  2MNH A;  2QEU A;  2ZLD A;  3PQU A;  2KXP B;  3NSG A;  4FSP A;  1Q9F A;  2R4N A;  5G39 A;  4LSI A;  3A2S X;  4O3Y A;  3JCU O;  4FZL A;  5GTI O;  2W80 C;  1IZN A;  4D64 A;  1T1L A;  3WI5 A;  3T24 A;  3T0S A;  1GU9 A;  3UPG A;  2R4P A;  3AA1 B;  1P8C A;  1OPF A;  2WJR A;  3VE2 A;  3WI4 A;  5DIK A;  4JFB A;  2R8A A;  3DWO X;  2OYO A;  3EMN X;  3QRC A;  4N59 A;  3VZW X;  2X27 X;  2MHL A;  2Y0H A;  4RLB A;  3POR A;  1H6S 1;  3SY7 A;  3SYS A;  4O49 A;  5G26 A;  5T5F A;  2LFU A;  4IL6 O;  4UB6 O;  4O3W A;  4FRX A;  2N2L A;  3LK3 B;  4LSF A;  3VZT X;  2PRR A;  5DIP A;  3KZI O;  2J1N A;  4C00 A;  3LK4 2;  2O4V A;  4C4V B;  2XE3 A;  3C1L A;  2K0L A;  4Z3T A;  2QTK A;  2F1T A;  2JQY A;  3AA0 B;  2J4U P;  2ES9 A;  4AKR A;  5AFU K;  2GE4 A;  4BUM X;  3VE1 A;  1BXW A;  4FQE A;  5GTH O;  3AA7 B;  3PF1 A;  4RJX A;  4AYM C;  4K3C A;  2R88 A;  4FZN A;  3C5O A;  2N2M A;  1PHO A;  4LSE A;  3PRN A;  3AAE A;  1IZN B;  5KAI O;  3K19 A;  3POU A;  2AXT O;  4FT6 A;  8PRN A;  4N58 A;  1GFM A;  3RBH A;  4AKM A;  3BEY A;  3DA4 A;  1HXX A;  2Y0K A;  3O0E A;  1G90 A;  1S5L O;  1YS5 A;  2IWW A;  3NJT A;  4PUX A;  2X9K A;  4FES A;  2XG6 A;  1Q9G A;  4KRA A;  3POX A;  4AUI A;  3QRA A;  4GCQ A;  3AAA A;  1HXT A;  3POQ A;  3PGU A;  3BS0 A;  5PRN A;  2XE2 A;  4PR7 A;  1OSM A;  3LK2 A;  4AYI D;  1GFO A;  2R4O A;  3LK4 1;  1LW1 A;  2XMX A;  5DL7 A;  4UB8 O;  7PRN A;  1ZHY A;  4XNK A;  1ZHX A;  5ADX L;  2XE1 A;  5H2F O;  2GMY A;  4PJ0 O;  4RLC A;  2Y2X A;  2OUW A;  2KZ7 A;  3LVY A;  2YNK A;  4CTD A;  4AKR B;  4AZL A;  4N75 A;  2YPV A;  5G3A A;  3HWB A;  2POR A;  2PRN A;  5EE2 A;  2JMM A;  3SY9 A;  2M07 A;  2O4D A;  3PGS A;  5DL6 A;  2XTQ A;  3TZG A;  1QJ8 A;  4FZM A;  5E79 O;  4GHB A;  3VZU X;  1E54 A;  4U9C A;  1T16 A;  5G38 A;  1ZHT A;  3AAE B;  4O4U A;  3PGR A;  1MM5 A;  1ORM A;  3D7I A;  1KNC A;  3AA6 A;  2JN8 A;  3PQS A;  2XE5 A;  1GFQ A;  3UU2 A;  1VKE A;  3SYB A;  2R4L A;  3GP6 A;  4KR8 A;  1GFN A;  3BRY A;  2ZFG A;  4FOZ A;  3SZD A;  1BH3 A;  3AAA B;  3UAQ A;  3LK2 B;  2IJC A;  1QJP A;  3DWN A;  4RL9 A;  4C69 X;  4D5U A;  2FGQ X;  1MM4 A;  4G9Q A;  2CWQ A;  2KZ7 B;  4F4B A;  4GF4 A;  3FYX A;  1GFP A;  3HOE A;  1HXU A;  2KXP A;  5KAF O;  3V8U A;  4D65 A;  4AYN A;  4FSO A;  1PRN A;  4O3X B;  4K3B A;  3JTY A;  3BRZ A;  4N74 A; 
#chains in the Genus database with same CATH homology
 4LSI A;  3A2S X;  3C5O A;  4O3Y A;  3TZG A;  2N2M A;  4FZL A;  1QJ8 A;  4FZM A;  2W80 C;  1IZN A;  4D64 A;  1ME5 A;  1PHO A;  5GV0 A;  4LSE A;  4GHB A;  3PRN A;  3T20 A;  3VZU X;  3AAE A;  3WI5 A;  4G75 A;  1E54 A;  1IZN B;  4U9C A;  3T24 A;  4FUV A;  3K19 A;  3POU A;  3T0S A;  2ODJ A;  5IYU A;  1GU9 A;  4FT6 A;  8PRN A;  4N58 A;  1GFM A;  3RBH A;  3AA1 A;  1ZHT A;  3AAE B;  4O4U A;  5FVN A;  5ADX K;  2Y0L A;  4AKM A;  1MM5 A;  1ORM A;  3UPG A;  5AFU L;  4GCP A;  3D7I A;  3VY9 X;  1KNC A;  1P8C A;  3AA6 A;  3BEY A;  1OPF A;  2F1V A;  3AA1 B;  2JN8 A;  3DA4 A;  1HXX A;  3VE2 A;  4E1T A;  2PFX A;  2Y0K A;  3PQS A;  3WI4 A;  2XE5 A;  5DIK A;  1GFQ A;  4JFB A;  3UU2 A;  2XTR A;  3O0E A;  1G90 A;  1VKE A;  3AA6 B;  1YS5 A;  2KC0 A;  3SYB A;  2OYO A;  3HW9 A;  4FRT A;  3EMN X;  1P4T A;  2W81 C;  3VY8 X;  3QRC A;  4N59 A;  3VZW X;  2X27 X;  2MHL A;  4KR8 A;  3GP6 A;  4PUX A;  4O3Z A;  2Y0H A;  1GFN A;  4RLB A;  2OMF A;  3SZV A;  4FES A;  2Q0T A;  1H6S 1;  1Q9G A;  2XG6 A;  3POR A;  4KRA A;  3G7G A;  4FMS A;  3POX A;  3SY7 A;  4AUI A;  1ZHW A;  3QRA A;  2K4T A;  3SYS A;  2ZFG A;  4FOZ A;  3SZD A;  4GCQ A;  4XNL A;  2FGR A;  3AAA A;  2KDY A;  4O49 A;  4AYD C;  4E1S A;  3HOL A;  5G26 A;  1HXT A;  3POQ A;  4G76 A;  5DL8 A;  5T5F A;  5PRN A;  2XE2 A;  2LHF A;  3LK3 A;  2LFU A;  4RJW A;  1OSM A;  1BH3 A;  3AAA B;  3LK2 A;  4O3W A;  4FRX A;  1MPF A;  2N2L A;  4AYI D;  3UAQ A;  1GFO A;  3LK3 B;  4LSF A;  6PRN A;  3LK2 B;  3LK4 1;  3VZT X;  1LW1 A;  2PRR A;  2XMX A;  5DL7 A;  7PRN A;  2IJC A;  5DIP A;  4GCS A;  1ZHY A;  2M06 A;  4LSH A;  1ZHZ A;  4XNK A;  1ZHX A;  5ADX L;  2J1N A;  4KR4 A;  2XE1 A;  1QJP A;  3LK4 2;  3AA0 A;  4O4X A;  2GMY A;  2O4V A;  4RL9 A;  4JCH A;  5JDP A;  3KVD D;  4C69 X;  2XE3 A;  1QJ9 A;  4RLC A;  5D5D A;  2Y2X A;  4D5U A;  3C1L A;  2OUW A;  2FGQ X;  2K0L A;  3DA3 A;  4Z3T A;  1MM4 A;  2F1T A;  2QTK A;  3AA0 B;  2KZ7 A;  4AFK A;  4B61 A;  3LVY A;  2J4U P;  4G9Q A;  2ES9 A;  4AKR A;  2YNK A;  5AFU K;  2GE4 A;  2CWQ A;  4BUM X;  5DL5 A;  3AA7 A;  2KZ7 B;  3VE1 A;  4F4B A;  1BT9 A;  4AKR B;  2ERV A;  4GF4 A;  1BXW A;  3FYX A;  1GFP A;  4QQ1 A;  4AZL A;  2Y7S A;  2AF7 A;  2YPV A;  3AA7 B;  3HOE A;  1HXU A;  3HWB A;  2KXP A;  1THQ A;  2POR A;  4RJX A;  3V8U A;  2PRN A;  4AYE C;  4AYM C;  4D65 A;  5EE2 A;  4AYN A;  4FSO A;  2MNH A;  2QEU A;  1PRN A;  2ZLD A;  4O3X B;  2JMM A;  3JTY A;  3PQU A;  2KXP B;  3SY9 A;  3NSG A;  2M07 A;  4FSP A;  1Q9F A;  2O4D A;  4FZN A;  5DL6 A;  2XTQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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