3AA6A

Crystal structure of actin capping protein in complex with the cp-binding motif derived from cd2ap
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
270
structure length
270
Chain Sequence
RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYDDQVLITEHGDLGNGRFLDPRNKISFKFDHLRKEASDPQPEDTESALKQWRDACDSALRAYVKDHYPNGFCTVYGKSIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVAAVLKIQVHYYEDGNVQLVSHKDIQDSVQVSSDVQTAKEFIKIIENAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Two distinct mechanisms for actin capping protein regulation--steric and allosteric inhibition
pubmed doi rcsb
molecule tags Protein binding
source organism Gallus gallus
molecule keywords F-actin-capping protein subunit alpha-1
total genus 87
structure length 270
sequence length 270
ec nomenclature
pdb deposition date 2009-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01267 F-actin_cap_A F-actin capping protein alpha subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 3aa6A01
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 3aa6A02
3LK3B 5AFUL 1IZNA 3AA6A 5AFUK 3LK2A 1IZNB 3AA7A 4AKRA 3AA6B 3LK41 3AA0A 3LK2B 3AA7B 4AKRB 5ADXL 2KXPA 3AA0B 3AAEA 2KXPB 3AAAA 2KZ7A 3AA1A 5ADXK 3AAEB 3LK42 3AAAB 2KZ7B 3AA1B 3LK3A
chains in the Genus database with same CATH superfamily
1E54A 1T1LA 2Y0LA 1T16A 2XG6A 2X9KA 3PQSA 1KNCA 4PJ0O 3PGSA 4GF4A 1GFMA 4AYNA 3NJTA 4FESA 5TISO 4D65A 2J4UP 3LK3B 5DL8A 5DL7A 4FUVA 3K19A 3VZUX 4K3BA 2R4OA 3LK2B 3A2SX 4LSFA 4FZMA 4D5UA 3WI4A 3AA1A 2QEUA 1OPFA 2MHLA 4G9QA 4Z3TA 3KVDD 4RJWA 4AUIA 4FRTA 3PORA 3C1LA 1HXUA 4K3CA 3BRYA 3BRZA 3SY9A 3QRAA 1ZHWA 4B61A 5D5DA 3BS0A 1Q9GA 3JCUO 3WU2O 3PQUA 3DWNA 3AAEA 3C5OA 3O0EA 2XE2A 4FZLA 5DL5A 3POUA 5G3AA 4O49A 3VY8X 4O3XB 2IJCA 2OUWA 1P4TA 1GFOA 1GFPA 5DL6A 3JTYA 3PGRA 1HXXA 3SZDA 1G90A 1THQA 3LK3A 1GU9A 4FSOA 3KZIO 5B5EO 2XTRA 4C00A 2QTKA 3T20A 2XMXA 3LK2A 4FQEA 1GFNA 4FSPA 3UU2A 2LHFA 2MNHA 4QQ1A 2CWQA 2GMYA 3POQA 2R89A 2K0LA 3RBHA 5KAFO 4FRXA 4C69X 2ZFGA 5AFUL 4KR8A 2XE3A 4PUXA 2YNKA 2Y0KA 4GCQA 2R4NA 4N75A 2WJRA 2XTQA 3HOLA 3HW9A 3AA6B 1BXWA 2R4LA 2YPVA 4LSEA 4AYMC 4FOZA 4AYID 2W81C 3A0HO 2F1TA 2LFUA 3HOEA 2Q0TA 4UB6O 1IZNA 2N2LA 5AFUK 3QRCA 3DZMA 3LK41 1ZHYA 3PF1A 2AF7A 3AA7B 4FT6A 3FYXA 2KXPB 2F1CX 3EMNX 1ZHZA 3AAAB 3DA4A 1QJPA 6PRNA 4KR4A 1MM4A 2ODJA 3SYBA 4RLBA 4O4XA 5EE2A 5E79O 2R4PA 3A0BO 2PFXA 3T0SA 5H2FO 2W80C 4AYEC 3T24A 3BEYA 3GP6A 4JFBA 4JCHA 5GV0A 2FGRA 1S5LO 4E1TA 7PRNA 4PR7A 4GCPA 2R8AA 5T5FA 3AA0B 4GHBA 3UPGA 5DIPA 2JQYA 1PHOA 2JMMA 3V8UA 3LK42 2KZ7B 4RLCA 3VE2A 5B66O 5KAIO 2GE4A 2ERVA 3D7IA 3AA6A 2X27X 4N74A 4U9CA 2Y7SA 4G75A 5ADXL 3G7GA 1ZHTA 4O3ZA 3LVYA 4LSIA 2F1VA 3VY9X 4O3WA 1MM5A 2AXTO 3SYSA 1P8CA 4FMSA 2JN8A 3PGUA 2OMFA 4LSHA 4AFKA 3AA7A 4D64A 3SY7A 4AKRB 5IYUA 3WI5A 2KXPA 1ME5A 2OYOA 4N58A 1QJ9A 3AAAA 4RJXA 3NSGA 5ADXK 2Y2XA 5GTHO 2WVPA 2Y0HA 4GCSA 4KRAA 2M07A 4C4VB 1ZHXA 2IWVA 4IL6O 1MPFA 1QJ8A 5FVNA 3UAQA 4AKMA 4AZLA 8PRNA 2J1NA 4BUMX 1BT9A 1YS5A 4O3YA 4UB8O 1PRNA 2M06A 3SZVA 5PRNA 2PRRA 1BH3A 4RL9A 2K4TA 2R88A 3VZTX 1LW1A 3AA0A 4F4BA 1H6S1 2O4VA 2KZ7A 5G38A 3VE1A 1Q9FA 2PRNA 3AA1B 4CTDA 5GTIO 3VZWX 4FZNA 4XNLA 2KC0A 2KDYA 2XE1A 2O4DA 4G76A 1IZNB 2ES9A 4AYDC 4N59A 3POXA 2WJQA 4O4UA 5JDPA 1VKEA 3PRNA 2ZLDA 1GFQA 1ORMA 3HWBA 3TZGA 4E1SA 1OSMA 1HXTA 3DWOX 4AKRA 2N2MA 2FGQX 2XE5A 5G39A 4XNKA 5G26A 2IWWA 5DIKA 2PORA 3AAEB 3DA3A 4C4VA
chains in the Genus database with same CATH topology
2Y0HA 4GCSA 4O49A 3VY8X 4KRAA 2M07A 1E54A 1QJPA 6PRNA 1ZHXA 4KR4A 1MM4A 4O3XB 2Y0LA 2ODJA 3SYBA 2XG6A 4RLBA 3PQSA 1KNCA 1MPFA 4O4XA 2IJCA 5EE2A 2OUWA 1P4TA 1GFOA 1QJ8A 5FVNA 3UAQA 1GFPA 5DL6A 4AKMA 4AZLA 3JTYA 4GF4A 1GFMA 2J1NA 4AYNA 4BUMX 8PRNA 1BT9A 1HXXA 3SZDA 2PFXA 1G90A 3T0SA 1YS5A 4FESA 1THQA 3LK3A 1GU9A 4FSOA 4O3YA 2W80C 4D65A 1PRNA 2M06A 2J4UP 3LK3B 5DL8A 5DL7A 4AYEC 2XTRA 3SZVA 3T24A 5PRNA 3BEYA 2PRRA 3GP6A 4FUVA 2QTKA 3K19A 4JFBA 4JCHA 3T20A 5GV0A 1BH3A 4RL9A 2XMXA 3VZUX 2K4TA 3LK2A 3VZTX 2FGRA 1GFNA 4FSPA 1LW1A 4E1TA 7PRNA 3AA0A 3LK2B 3UU2A 4F4BA 4GCPA 1H6S1 2LHFA 5T5FA 3A2SX 4LSFA 3AA0B 4FZMA 4GHBA 4D5UA 2MNHA 3WI4A 3UPGA 5DIPA 2O4VA 4QQ1A 2KZ7A 3AA1A 1PHOA 2JMMA 2CWQA 2GMYA 3V8UA 3VE1A 3POQA 1Q9FA 2QEUA 2PRNA 2KZ7B 2K0LA 3AA1B 3LK42 3RBHA 1OPFA 3VZWX 4FZNA 4RLCA 3VE2A 4FRXA 4XNLA 4C69X 2ZFGA 5AFUL 4KR8A 2KC0A 2KDYA 2XE1A 2MHLA 4G9QA 2XE3A 2O4DA 4Z3TA 2GE4A 3KVDD 4PUXA 2ERVA 3D7IA 4G76A 4RJWA 2YNKA 3AA6A 2Y0KA 4GCQA 4AUIA 2X27X 1IZNB 4FRTA 3HOLA 2XTQA 3HW9A 4U9CA 3AA6B 1BXWA 2Y7SA 4G75A 2ES9A 3G7GA 1ZHTA 4AYDC 5ADXL 4N59A 4O3ZA 3LVYA 4LSIA 2F1VA 2YPVA 3VY9X 3PORA 3POXA 4LSEA 4AYMC 3C1LA 4FOZA 4AYID 2W81C 4O3WA 1HXUA 1MM5A 4O4UA 5JDPA 1VKEA 2F1TA 3SYSA 3PRNA 2LFUA 3SY9A 2ZLDA 3QRAA 1P8CA 4FMSA 2JN8A 1ZHWA 3HOEA 1GFQA 1ORMA 3HWBA 3TZGA 4E1SA 2Q0TA 4B61A 2OMFA 1IZNA 1OSMA 4LSHA 1HXTA 2N2LA 5AFUK 4AFKA 3AA7A 4AKRA 5D5DA 3QRCA 2N2MA 3LK41 2FGQX 4D64A 1ZHYA 3SY7A 2AF7A 1Q9GA 3AA7B 4AKRB 5IYUA 2XE5A 3WI5A 2KXPA 4FT6A 1ME5A 3PQUA 4XNKA 3FYXA 5G26A 3AAEA 2OYOA 2KXPB 5DIKA 2PORA 3C5OA 1QJ9A 3AAAA 4N58A 3NSGA 4RJXA 3O0EA 5ADXK 3EMNX 2Y2XA 1ZHZA 3AAEB 3DA3A 3AAAB 2XE2A 3DA4A 4FZLA 5DL5A 3POUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LK3 B;  5AFU L;  1IZN A;  3AA6 A;  5AFU K;  3LK2 A;  1IZN B;  3AA7 A;  4AKR A;  3AA6 B;  3LK4 1;  3AA0 A;  3LK2 B;  3AA7 B;  4AKR B;  5ADX L;  2KXP A;  3AA0 B;  3AAE A;  2KXP B;  3AAA A;  2KZ7 A;  3AA1 A;  5ADX K;  3AAE B;  3LK4 2;  3AAA B;  2KZ7 B;  3AA1 B;  3LK3 A; 
#chains in the Genus database with same CATH topology
 1E54 A;  1T1L A;  2Y0L A;  1T16 A;  2XG6 A;  2X9K A;  3PQS A;  1KNC A;  4PJ0 O;  3PGS A;  4GF4 A;  1GFM A;  4AYN A;  3NJT A;  4FES A;  5TIS O;  4D65 A;  2J4U P;  3LK3 B;  5DL8 A;  5DL7 A;  4FUV A;  3K19 A;  3VZU X;  4K3B A;  2R4O A;  3LK2 B;  3A2S X;  4LSF A;  4FZM A;  4D5U A;  3WI4 A;  3AA1 A;  2QEU A;  1OPF A;  2MHL A;  4G9Q A;  4Z3T A;  3KVD D;  4RJW A;  4AUI A;  4FRT A;  3POR A;  3C1L A;  1HXU A;  4K3C A;  3BRY A;  3BRZ A;  3SY9 A;  3QRA A;  1ZHW A;  4B61 A;  5D5D A;  3BS0 A;  1Q9G A;  3JCU O;  3WU2 O;  3PQU A;  3DWN A;  3AAE A;  3C5O A;  3O0E A;  2XE2 A;  4FZL A;  5DL5 A;  3POU A;  5G3A A;  4O49 A;  3VY8 X;  4O3X B;  2IJC A;  2OUW A;  1P4T A;  1GFO A;  1GFP A;  5DL6 A;  3JTY A;  3PGR A;  1HXX A;  3SZD A;  1G90 A;  1THQ A;  3LK3 A;  1GU9 A;  4FSO A;  3KZI O;  5B5E O;  2XTR A;  4C00 A;  2QTK A;  3T20 A;  2XMX A;  3LK2 A;  4FQE A;  1GFN A;  4FSP A;  3UU2 A;  2LHF A;  2MNH A;  4QQ1 A;  2CWQ A;  2GMY A;  3POQ A;  2R89 A;  2K0L A;  3RBH A;  5KAF O;  4FRX A;  4C69 X;  2ZFG A;  5AFU L;  4KR8 A;  2XE3 A;  4PUX A;  2YNK A;  2Y0K A;  4GCQ A;  2R4N A;  4N75 A;  2WJR A;  2XTQ A;  3HOL A;  3HW9 A;  3AA6 B;  1BXW A;  2R4L A;  2YPV A;  4LSE A;  4AYM C;  4FOZ A;  4AYI D;  2W81 C;  3A0H O;  2F1T A;  2LFU A;  3HOE A;  2Q0T A;  4UB6 O;  1IZN A;  2N2L A;  5AFU K;  3QRC A;  3DZM A;  3LK4 1;  1ZHY A;  3PF1 A;  2AF7 A;  3AA7 B;  4FT6 A;  3FYX A;  2KXP B;  2F1C X;  3EMN X;  1ZHZ A;  3AAA B;  3DA4 A;  1QJP A;  6PRN A;  4KR4 A;  1MM4 A;  2ODJ A;  3SYB A;  4RLB A;  4O4X A;  5EE2 A;  5E79 O;  2R4P A;  3A0B O;  2PFX A;  3T0S A;  5H2F O;  2W80 C;  4AYE C;  3T24 A;  3BEY A;  3GP6 A;  4JFB A;  4JCH A;  5GV0 A;  2FGR A;  1S5L O;  4E1T A;  7PRN A;  4PR7 A;  4GCP A;  2R8A A;  5T5F A;  3AA0 B;  4GHB A;  3UPG A;  5DIP A;  2JQY A;  1PHO A;  2JMM A;  3V8U A;  3LK4 2;  2KZ7 B;  4RLC A;  3VE2 A;  5B66 O;  5KAI O;  2GE4 A;  2ERV A;  3D7I A;  3AA6 A;  2X27 X;  4N74 A;  4U9C A;  2Y7S A;  4G75 A;  5ADX L;  3G7G A;  1ZHT A;  4O3Z A;  3LVY A;  4LSI A;  2F1V A;  3VY9 X;  4O3W A;  1MM5 A;  2AXT O;  3SYS A;  1P8C A;  4FMS A;  2JN8 A;  3PGU A;  2OMF A;  4LSH A;  4AFK A;  3AA7 A;  4D64 A;  3SY7 A;  4AKR B;  5IYU A;  3WI5 A;  2KXP A;  1ME5 A;  2OYO A;  4N58 A;  1QJ9 A;  3AAA A;  4RJX A;  3NSG A;  5ADX K;  2Y2X A;  5GTH O;  2WVP A;  2Y0H A;  4GCS A;  4KRA A;  2M07 A;  4C4V B;  1ZHX A;  2IWV A;  4IL6 O;  1MPF A;  1QJ8 A;  5FVN A;  3UAQ A;  4AKM A;  4AZL A;  8PRN A;  2J1N A;  4BUM X;  1BT9 A;  1YS5 A;  4O3Y A;  4UB8 O;  1PRN A;  2M06 A;  3SZV A;  5PRN A;  2PRR A;  1BH3 A;  4RL9 A;  2K4T A;  2R88 A;  3VZT X;  1LW1 A;  3AA0 A;  4F4B A;  1H6S 1;  2O4V A;  2KZ7 A;  5G38 A;  3VE1 A;  1Q9F A;  2PRN A;  3AA1 B;  4CTD A;  5GTI O;  3VZW X;  4FZN A;  4XNL A;  2KC0 A;  2KDY A;  2XE1 A;  2O4D A;  4G76 A;  1IZN B;  2ES9 A;  4AYD C;  4N59 A;  3POX A;  2WJQ A;  4O4U A;  5JDP A;  1VKE A;  3PRN A;  2ZLD A;  1GFQ A;  1ORM A;  3HWB A;  3TZG A;  4E1S A;  1OSM A;  1HXT A;  3DWO X;  4AKR A;  2N2M A;  2FGQ X;  2XE5 A;  5G39 A;  4XNK A;  5G26 A;  2IWW A;  5DIK A;  2POR A;  3AAE B;  3DA3 A;  4C4V A; 
#chains in the Genus database with same CATH homology
 2Y0H A;  4GCS A;  4O49 A;  3VY8 X;  4KRA A;  2M07 A;  1E54 A;  1QJP A;  6PRN A;  1ZHX A;  4KR4 A;  1MM4 A;  4O3X B;  2Y0L A;  2ODJ A;  3SYB A;  2XG6 A;  4RLB A;  3PQS A;  1KNC A;  1MPF A;  4O4X A;  2IJC A;  5EE2 A;  2OUW A;  1P4T A;  1GFO A;  1QJ8 A;  5FVN A;  3UAQ A;  1GFP A;  5DL6 A;  4AKM A;  4AZL A;  3JTY A;  4GF4 A;  1GFM A;  2J1N A;  4AYN A;  4BUM X;  8PRN A;  1BT9 A;  1HXX A;  3SZD A;  2PFX A;  1G90 A;  3T0S A;  1YS5 A;  4FES A;  1THQ A;  3LK3 A;  1GU9 A;  4FSO A;  4O3Y A;  2W80 C;  4D65 A;  1PRN A;  2M06 A;  2J4U P;  3LK3 B;  5DL8 A;  5DL7 A;  4AYE C;  2XTR A;  3SZV A;  3T24 A;  5PRN A;  3BEY A;  2PRR A;  3GP6 A;  4FUV A;  2QTK A;  3K19 A;  4JFB A;  4JCH A;  3T20 A;  5GV0 A;  1BH3 A;  4RL9 A;  2XMX A;  3VZU X;  2K4T A;  3LK2 A;  3VZT X;  2FGR A;  1GFN A;  4FSP A;  1LW1 A;  4E1T A;  7PRN A;  3AA0 A;  3LK2 B;  3UU2 A;  4F4B A;  4GCP A;  1H6S 1;  2LHF A;  5T5F A;  3A2S X;  4LSF A;  3AA0 B;  4FZM A;  4GHB A;  4D5U A;  2MNH A;  3WI4 A;  3UPG A;  5DIP A;  2O4V A;  4QQ1 A;  2KZ7 A;  3AA1 A;  1PHO A;  2JMM A;  2CWQ A;  2GMY A;  3V8U A;  3VE1 A;  3POQ A;  1Q9F A;  2QEU A;  2PRN A;  2KZ7 B;  2K0L A;  3AA1 B;  3LK4 2;  3RBH A;  1OPF A;  3VZW X;  4FZN A;  4RLC A;  3VE2 A;  4FRX A;  4XNL A;  4C69 X;  2ZFG A;  5AFU L;  4KR8 A;  2KC0 A;  2KDY A;  2XE1 A;  2MHL A;  4G9Q A;  2XE3 A;  2O4D A;  4Z3T A;  2GE4 A;  3KVD D;  4PUX A;  2ERV A;  3D7I A;  4G76 A;  4RJW A;  2YNK A;  3AA6 A;  2Y0K A;  4GCQ A;  4AUI A;  2X27 X;  1IZN B;  4FRT A;  3HOL A;  2XTQ A;  3HW9 A;  4U9C A;  3AA6 B;  1BXW A;  2Y7S A;  4G75 A;  2ES9 A;  3G7G A;  1ZHT A;  4AYD C;  5ADX L;  4N59 A;  4O3Z A;  3LVY A;  4LSI A;  2F1V A;  2YPV A;  3VY9 X;  3POR A;  3POX A;  4LSE A;  4AYM C;  3C1L A;  4FOZ A;  4AYI D;  2W81 C;  4O3W A;  1HXU A;  1MM5 A;  4O4U A;  5JDP A;  1VKE A;  2F1T A;  3SYS A;  3PRN A;  2LFU A;  3SY9 A;  2ZLD A;  3QRA A;  1P8C A;  4FMS A;  2JN8 A;  1ZHW A;  3HOE A;  1GFQ A;  1ORM A;  3HWB A;  3TZG A;  4E1S A;  2Q0T A;  4B61 A;  2OMF A;  1IZN A;  1OSM A;  4LSH A;  1HXT A;  2N2L A;  5AFU K;  4AFK A;  3AA7 A;  4AKR A;  5D5D A;  3QRC A;  2N2M A;  3LK4 1;  2FGQ X;  4D64 A;  1ZHY A;  3SY7 A;  2AF7 A;  1Q9G A;  3AA7 B;  4AKR B;  5IYU A;  2XE5 A;  3WI5 A;  2KXP A;  4FT6 A;  1ME5 A;  3PQU A;  4XNK A;  3FYX A;  5G26 A;  3AAE A;  2OYO A;  2KXP B;  5DIK A;  2POR A;  3C5O A;  1QJ9 A;  3AAA A;  4N58 A;  3NSG A;  4RJX A;  3O0E A;  5ADX K;  3EMN X;  2Y2X A;  1ZHZ A;  3AAE B;  3DA3 A;  3AAA B;  2XE2 A;  3DA4 A;  4FZL A;  5DL5 A;  3POU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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