3AA6A

Crystal structure of actin capping protein in complex with the cp-binding motif derived from cd2ap
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
270
structure length
270
Chain Sequence
RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYDDQVLITEHGDLGNGRFLDPRNKISFKFDHLRKEASDPQPEDTESALKQWRDACDSALRAYVKDHYPNGFCTVYGKSIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVAAVLKIQVHYYEDGNVQLVSHKDIQDSVQVSSDVQTAKEFIKIIENAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Two distinct mechanisms for actin capping protein regulation--steric and allosteric inhibition
pubmed doi rcsb
source organism Gallus gallus
molecule tags Protein binding
molecule keywords F-actin-capping protein subunit alpha-1
total genus 87
structure length 270
sequence length 270
ec nomenclature
pdb deposition date 2009-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01267 F-actin_cap_A F-actin capping protein alpha subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 3aa6A01
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 3aa6A02
4AKRB 3LK3B 3LK42 5AFUL 5ADXL 2KZ7B 4AKRA 3AA1A 5ADXK 2KZ7A 3LK41 3AAEA 1IZNB 3AA7A 3AA0B 3LK2A 3AA6A 3AAAA 5AFUK 3LK3A 3LK2B 3AA1B 3AA7B 3AA0A 3AAEB 2KXPA 1IZNA 2KXPB 3AA6B 3AAAB
chains in the Genus database with same CATH superfamily
3PORA 1BT9A 5PRNA 4C4VB 2GE4A 3T20A 4LSHA 1GFQA 4N75A 1HXXA 5G26A 4IL6O 2CWQA 4UB8O 1QJ8A 2X27X 3RBHA 2R4LA 4KRAA 4O3ZA 2ZFGA 3PGSA 2KDYA 4U9CA 4D64A 3SY9A 3DWNA 5G38A 1H6S1 3JCUO 1ZHTA 2ERVA 3V8UA 2N2MA 1E54A 3VE1A 2ODJA 5ADXK 4K3BA 3VZWX 2R4PA 3LK41 1GFOA 1IZNB 3T0SA 1T1LA 2F1TA 2IWWA 3D7IA 4JCHA 5DL5A 3LVYA 1ZHWA 3A0HO 1S5LO 3LK2A 3AA6A 1GFMA 3K19A 2WJQA 4FZLA 3SY7A 3LK3A 2MNHA 3AA1B 1VKEA 4D65A 4XNLA 5H2FO 5KAFO 5DL8A 3UAQA 2XE3A 1LW1A 1IZNA 1OSMA 2R8AA 2Y0LA 4JFBA 4C00A 4PR7A 2PRNA 5DIPA 3HW9A 2KXPB 4FUVA 5GV0A 3AA6B 4BUMX 4LSIA 1YS5A 2OMFA 3HOEA 1GFNA 2XTQA 1THQA 3BRYA 4AKMA 3KVDD 4AUIA 2XE1A 3POQA 4RJXA 4KR4A 3DA3A 3O0EA 2GMYA 1Q9GA 5T5FA 2AF7A 4AYMC 4AFKA 4N74A 5DL7A 3SZDA 2XTRA 2K4TA 2QEUA 4D5UA 2F1VA 2R4NA 3POUA 1G90A 2YPVA 2FGRA 2XE2A 3EMNX 3PGRA 3UU2A 2J4UP 1GFPA 2OYOA 4AYDC 4G75A 2XE5A 2K0LA 3BEYA 3LK2B 3PQUA 4FSPA 1PRNA 5EE2A 3A0BO 3AAEB 2N2LA 4AYID 1ORMA 2Q0TA 2JMMA 3DWOX 4XNKA 4GCPA 2AXTO 2M07A 3VZUX 1MM4A 4CTDA 2IJCA 4FQEA 5FVNA 4GCSA 2PORA 2Y0KA 3AAAB 1KNCA 1QJ9A 1ZHYA 4RL9A 3T24A 2JN8A 2PRRA 3HOLA 2QTKA 5KAIO 7PRNA 1ZHZA 2OUWA 2R4OA 3QRAA 5AFUL 3FYXA 4PUXA 5D5DA 5B5EO 8PRNA 3UPGA 4LSFA 4RLBA 4RLCA 5JDPA 4AKRA 3POXA 4PJ0O 2ES9A 3AA1A 4F4BA 1BH3A 4G76A 1GU9A 4O4UA 3WI5A 2KZ7A 2O4DA 4O3XB 3WU2O 4FSOA 4LSEA 3GP6A 3AA7A 3NJTA 5TISO 3AA0B 3BRZA 2KC0A 2PFXA 2O4VA 3SZVA 2LHFA 1BXWA 5AFUK 4FZMA 2XMXA 2MHLA 3C5OA 4K3CA 5GTIO 4E1SA 1MM5A 4QQ1A 5G3AA 1HXUA 5DL6A 1P8CA 3A2SX 4FRXA 3WI4A 2FGQX 3KZIO 5G39A 3G7GA 2R89A 3BS0A 5ADXL 2F1CX 4KR8A 6PRNA 5IYUA 4AKRB 2YNKA 1OPFA 3PRNA 2J1NA 3LK3B 2W80C 4FT6A 4O4XA 5E79O 3DZMA 3TZGA 2IWVA 2W81C 4C4VA 2WVPA 1ME5A 2JQYA 2Y7SA 3LK42 1Q9FA 2KZ7B 4GCQA 3VE2A 1MPFA 4E1TA 3HWBA 4GHBA 5B66O 2LFUA 4FOZA 4FZNA 3SYBA 2WJRA 4GF4A 5GTHO 4O49A 4AYNA 3VY9X 3C1LA 4UB6O 3AAEA 4Z3TA 3PGUA 2XG6A 4B61A 2M06A 1ZHXA 2ZLDA 1QJPA 4FRTA 2Y2XA 3AAAA 3QRCA 2X9KA 3VY8X 4AYEC 1P4TA 3PQSA 3NSGA 4RJWA 4G9QA 4N59A 2R88A 5DIKA 3AA7B 3AA0A 2Y0HA 4FESA 1HXTA 4N58A 2KXPA 3JTYA 4O3YA 4AZLA 3VZTX 1T16A 4O3WA 3SYSA 3DA4A 3PF1A 4C69X 4FMSA 1PHOA
chains in the Genus database with same CATH topology
3PORA 1BT9A 2GE4A 3T20A 4LSHA 1GFQA 1HXXA 5G26A 2CWQA 1QJ8A 2X27X 3RBHA 4KRAA 4O3ZA 2ZFGA 4U9CA 2KDYA 4D64A 3SY9A 1H6S1 1ZHTA 2ERVA 3V8UA 2N2MA 1E54A 3VE1A 2ODJA 5ADXK 3VZWX 3LK41 1GFOA 1IZNB 3T0SA 2F1TA 3D7IA 4JCHA 5DL5A 3LVYA 1ZHWA 3LK2A 3AA6A 1GFMA 3K19A 4FZLA 3SY7A 3LK3A 2MNHA 3AA1B 1VKEA 4D65A 4XNLA 3UAQA 5DL8A 2XE3A 1LW1A 1IZNA 1OSMA 2Y0LA 4JFBA 2PRNA 5DIPA 3HW9A 2KXPB 4FUVA 5GV0A 3AA6B 4BUMX 4LSIA 1YS5A 2OMFA 3HOEA 1GFNA 2XTQA 1THQA 4AKMA 3KVDD 4AUIA 2XE1A 3POQA 4RJXA 4KR4A 3DA3A 3O0EA 2GMYA 1Q9GA 5T5FA 2AF7A 4AYMC 4AFKA 5DL7A 3SZDA 2XTRA 2K4TA 2QEUA 4D5UA 2F1VA 3POUA 1G90A 2YPVA 2FGRA 2XE2A 3EMNX 3UU2A 2J4UP 1GFPA 2OYOA 4AYDC 4G75A 2XE5A 2K0LA 3BEYA 3LK2B 3PQUA 4FSPA 1PRNA 5EE2A 3AAEB 2N2LA 4AYID 1ORMA 2Q0TA 2JMMA 4XNKA 4GCPA 2M07A 3VZUX 1MM4A 2IJCA 5FVNA 4GCSA 2PORA 2Y0KA 3AAAB 1KNCA 1QJ9A 1ZHYA 4RL9A 3T24A 2JN8A 2PRRA 3HOLA 2QTKA 7PRNA 1ZHZA 2OUWA 5AFUL 3QRAA 3FYXA 4PUXA 5D5DA 3UPGA 4LSFA 4RLBA 4RLCA 5JDPA 4AKRA 3POXA 2ES9A 3AA1A 4F4BA 1BH3A 4G76A 1GU9A 4O4UA 3WI5A 2KZ7A 2O4DA 4O3XB 4FSOA 4LSEA 3GP6A 3AA7A 3AA0B 2KC0A 2PFXA 2O4VA 3SZVA 2LHFA 1BXWA 5AFUK 4FZMA 2XMXA 2MHLA 3C5OA 4E1SA 1MM5A 4QQ1A 1HXUA 5DL6A 1P8CA 3A2SX 4FRXA 3WI4A 2FGQX 3G7GA 5IYUA 6PRNA 4KR8A 4AKRB 2YNKA 1OPFA 3PRNA 2J1NA 3LK3B 2W80C 4FT6A 4O4XA 3TZGA 2W81C 3LK42 1ME5A 2Y7SA 4GCQA 3VE2A 1Q9FA 2KZ7B 4E1TA 5ADXL 1MPFA 3HWBA 4GHBA 2LFUA 4FOZA 4FZNA 3SYBA 4GF4A 4O49A 4AYNA 3VY9X 3C1LA 3AAEA 4Z3TA 2XG6A 4B61A 2M06A 1ZHXA 2ZLDA 1QJPA 4FRTA 2Y2XA 3AAAA 3QRCA 4AYEC 3VY8X 8PRNA 1P4TA 3PQSA 3NSGA 4RJWA 4G9QA 4N59A 3AA7B 5DIKA 5PRNA 3AA0A 2Y0HA 4FESA 1HXTA 4N58A 2KXPA 3JTYA 4O3YA 4AZLA 3VZTX 4O3WA 3SYSA 3DA4A 4C69X 4FMSA 1PHOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AKR B;  3LK3 B;  3LK4 2;  5AFU L;  5ADX L;  2KZ7 B;  4AKR A;  3AA1 A;  5ADX K;  2KZ7 A;  3LK4 1;  3AAE A;  1IZN B;  3AA7 A;  3AA0 B;  3LK2 A;  3AA6 A;  3AAA A;  5AFU K;  3LK3 A;  3LK2 B;  3AA1 B;  3AA7 B;  3AA0 A;  3AAE B;  2KXP A;  1IZN A;  2KXP B;  3AA6 B;  3AAA B; 
#chains in the Genus database with same CATH topology
 3POR A;  1BT9 A;  5PRN A;  4C4V B;  2GE4 A;  3T20 A;  4LSH A;  1GFQ A;  4N75 A;  1HXX A;  5G26 A;  4IL6 O;  2CWQ A;  4UB8 O;  1QJ8 A;  2X27 X;  3RBH A;  2R4L A;  4KRA A;  4O3Z A;  2ZFG A;  3PGS A;  2KDY A;  4U9C A;  4D64 A;  3SY9 A;  3DWN A;  5G38 A;  1H6S 1;  3JCU O;  1ZHT A;  2ERV A;  3V8U A;  2N2M A;  1E54 A;  3VE1 A;  2ODJ A;  5ADX K;  4K3B A;  3VZW X;  2R4P A;  3LK4 1;  1GFO A;  1IZN B;  3T0S A;  1T1L A;  2F1T A;  2IWW A;  3D7I A;  4JCH A;  5DL5 A;  3LVY A;  1ZHW A;  3A0H O;  1S5L O;  3LK2 A;  3AA6 A;  1GFM A;  3K19 A;  2WJQ A;  4FZL A;  3SY7 A;  3LK3 A;  2MNH A;  3AA1 B;  1VKE A;  4D65 A;  4XNL A;  5H2F O;  5KAF O;  5DL8 A;  3UAQ A;  2XE3 A;  1LW1 A;  1IZN A;  1OSM A;  2R8A A;  2Y0L A;  4JFB A;  4C00 A;  4PR7 A;  2PRN A;  5DIP A;  3HW9 A;  2KXP B;  4FUV A;  5GV0 A;  3AA6 B;  4BUM X;  4LSI A;  1YS5 A;  2OMF A;  3HOE A;  1GFN A;  2XTQ A;  1THQ A;  3BRY A;  4AKM A;  3KVD D;  4AUI A;  2XE1 A;  3POQ A;  4RJX A;  4KR4 A;  3DA3 A;  3O0E A;  2GMY A;  1Q9G A;  5T5F A;  2AF7 A;  4AYM C;  4AFK A;  4N74 A;  5DL7 A;  3SZD A;  2XTR A;  2K4T A;  2QEU A;  4D5U A;  2F1V A;  2R4N A;  3POU A;  1G90 A;  2YPV A;  2FGR A;  2XE2 A;  3EMN X;  3PGR A;  3UU2 A;  2J4U P;  1GFP A;  2OYO A;  4AYD C;  4G75 A;  2XE5 A;  2K0L A;  3BEY A;  3LK2 B;  3PQU A;  4FSP A;  1PRN A;  5EE2 A;  3A0B O;  3AAE B;  2N2L A;  4AYI D;  1ORM A;  2Q0T A;  2JMM A;  3DWO X;  4XNK A;  4GCP A;  2AXT O;  2M07 A;  3VZU X;  1MM4 A;  4CTD A;  2IJC A;  4FQE A;  5FVN A;  4GCS A;  2POR A;  2Y0K A;  3AAA B;  1KNC A;  1QJ9 A;  1ZHY A;  4RL9 A;  3T24 A;  2JN8 A;  2PRR A;  3HOL A;  2QTK A;  5KAI O;  7PRN A;  1ZHZ A;  2OUW A;  2R4O A;  3QRA A;  5AFU L;  3FYX A;  4PUX A;  5D5D A;  5B5E O;  8PRN A;  3UPG A;  4LSF A;  4RLB A;  4RLC A;  5JDP A;  4AKR A;  3POX A;  4PJ0 O;  2ES9 A;  3AA1 A;  4F4B A;  1BH3 A;  4G76 A;  1GU9 A;  4O4U A;  3WI5 A;  2KZ7 A;  2O4D A;  4O3X B;  3WU2 O;  4FSO A;  4LSE A;  3GP6 A;  3AA7 A;  3NJT A;  5TIS O;  3AA0 B;  3BRZ A;  2KC0 A;  2PFX A;  2O4V A;  3SZV A;  2LHF A;  1BXW A;  5AFU K;  4FZM A;  2XMX A;  2MHL A;  3C5O A;  4K3C A;  5GTI O;  4E1S A;  1MM5 A;  4QQ1 A;  5G3A A;  1HXU A;  5DL6 A;  1P8C A;  3A2S X;  4FRX A;  3WI4 A;  2FGQ X;  3KZI O;  5G39 A;  3G7G A;  2R89 A;  3BS0 A;  5ADX L;  2F1C X;  4KR8 A;  6PRN A;  5IYU A;  4AKR B;  2YNK A;  1OPF A;  3PRN A;  2J1N A;  3LK3 B;  2W80 C;  4FT6 A;  4O4X A;  5E79 O;  3DZM A;  3TZG A;  2IWV A;  2W81 C;  4C4V A;  2WVP A;  1ME5 A;  2JQY A;  2Y7S A;  3LK4 2;  1Q9F A;  2KZ7 B;  4GCQ A;  3VE2 A;  1MPF A;  4E1T A;  3HWB A;  4GHB A;  5B66 O;  2LFU A;  4FOZ A;  4FZN A;  3SYB A;  2WJR A;  4GF4 A;  5GTH O;  4O49 A;  4AYN A;  3VY9 X;  3C1L A;  4UB6 O;  3AAE A;  4Z3T A;  3PGU A;  2XG6 A;  4B61 A;  2M06 A;  1ZHX A;  2ZLD A;  1QJP A;  4FRT A;  2Y2X A;  3AAA A;  3QRC A;  2X9K A;  3VY8 X;  4AYE C;  1P4T A;  3PQS A;  3NSG A;  4RJW A;  4G9Q A;  4N59 A;  2R88 A;  5DIK A;  3AA7 B;  3AA0 A;  2Y0H A;  4FES A;  1HXT A;  4N58 A;  2KXP A;  3JTY A;  4O3Y A;  4AZL A;  3VZT X;  1T16 A;  4O3W A;  3SYS A;  3DA4 A;  3PF1 A;  4C69 X;  4FMS A;  1PHO A; 
#chains in the Genus database with same CATH homology
 3POR A;  1BT9 A;  2GE4 A;  3T20 A;  4LSH A;  1GFQ A;  1HXX A;  5G26 A;  2CWQ A;  1QJ8 A;  2X27 X;  3RBH A;  4KRA A;  4O3Z A;  2ZFG A;  4U9C A;  2KDY A;  4D64 A;  3SY9 A;  1H6S 1;  1ZHT A;  2ERV A;  3V8U A;  2N2M A;  1E54 A;  3VE1 A;  2ODJ A;  5ADX K;  3VZW X;  3LK4 1;  1GFO A;  1IZN B;  3T0S A;  2F1T A;  3D7I A;  4JCH A;  5DL5 A;  3LVY A;  1ZHW A;  3LK2 A;  3AA6 A;  1GFM A;  3K19 A;  4FZL A;  3SY7 A;  3LK3 A;  2MNH A;  3AA1 B;  1VKE A;  4D65 A;  4XNL A;  3UAQ A;  5DL8 A;  2XE3 A;  1LW1 A;  1IZN A;  1OSM A;  2Y0L A;  4JFB A;  2PRN A;  5DIP A;  3HW9 A;  2KXP B;  4FUV A;  5GV0 A;  3AA6 B;  4BUM X;  4LSI A;  1YS5 A;  2OMF A;  3HOE A;  1GFN A;  2XTQ A;  1THQ A;  4AKM A;  3KVD D;  4AUI A;  2XE1 A;  3POQ A;  4RJX A;  4KR4 A;  3DA3 A;  3O0E A;  2GMY A;  1Q9G A;  5T5F A;  2AF7 A;  4AYM C;  4AFK A;  5DL7 A;  3SZD A;  2XTR A;  2K4T A;  2QEU A;  4D5U A;  2F1V A;  3POU A;  1G90 A;  2YPV A;  2FGR A;  2XE2 A;  3EMN X;  3UU2 A;  2J4U P;  1GFP A;  2OYO A;  4AYD C;  4G75 A;  2XE5 A;  2K0L A;  3BEY A;  3LK2 B;  3PQU A;  4FSP A;  1PRN A;  5EE2 A;  3AAE B;  2N2L A;  4AYI D;  1ORM A;  2Q0T A;  2JMM A;  4XNK A;  4GCP A;  2M07 A;  3VZU X;  1MM4 A;  2IJC A;  5FVN A;  4GCS A;  2POR A;  2Y0K A;  3AAA B;  1KNC A;  1QJ9 A;  1ZHY A;  4RL9 A;  3T24 A;  2JN8 A;  2PRR A;  3HOL A;  2QTK A;  7PRN A;  1ZHZ A;  2OUW A;  5AFU L;  3QRA A;  3FYX A;  4PUX A;  5D5D A;  3UPG A;  4LSF A;  4RLB A;  4RLC A;  5JDP A;  4AKR A;  3POX A;  2ES9 A;  3AA1 A;  4F4B A;  1BH3 A;  4G76 A;  1GU9 A;  4O4U A;  3WI5 A;  2KZ7 A;  2O4D A;  4O3X B;  4FSO A;  4LSE A;  3GP6 A;  3AA7 A;  3AA0 B;  2KC0 A;  2PFX A;  2O4V A;  3SZV A;  2LHF A;  1BXW A;  5AFU K;  4FZM A;  2XMX A;  2MHL A;  3C5O A;  4E1S A;  1MM5 A;  4QQ1 A;  1HXU A;  5DL6 A;  1P8C A;  3A2S X;  4FRX A;  3WI4 A;  2FGQ X;  3G7G A;  5IYU A;  6PRN A;  4KR8 A;  4AKR B;  2YNK A;  1OPF A;  3PRN A;  2J1N A;  3LK3 B;  2W80 C;  4FT6 A;  4O4X A;  3TZG A;  2W81 C;  3LK4 2;  1ME5 A;  2Y7S A;  4GCQ A;  3VE2 A;  1Q9F A;  2KZ7 B;  4E1T A;  5ADX L;  1MPF A;  3HWB A;  4GHB A;  2LFU A;  4FOZ A;  4FZN A;  3SYB A;  4GF4 A;  4O49 A;  4AYN A;  3VY9 X;  3C1L A;  3AAE A;  4Z3T A;  2XG6 A;  4B61 A;  2M06 A;  1ZHX A;  2ZLD A;  1QJP A;  4FRT A;  2Y2X A;  3AAA A;  3QRC A;  4AYE C;  3VY8 X;  8PRN A;  1P4T A;  3PQS A;  3NSG A;  4RJW A;  4G9Q A;  4N59 A;  3AA7 B;  5DIK A;  5PRN A;  3AA0 A;  2Y0H A;  4FES A;  1HXT A;  4N58 A;  2KXP A;  3JTY A;  4O3Y A;  4AZL A;  3VZT X;  4O3W A;  3SYS A;  3DA4 A;  4C69 X;  4FMS A;  1PHO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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