3AA6A

Crystal structure of actin capping protein in complex with the cp-binding motif derived from cd2ap
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
270
structure length
270
Chain Sequence
RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYDDQVLITEHGDLGNGRFLDPRNKISFKFDHLRKEASDPQPEDTESALKQWRDACDSALRAYVKDHYPNGFCTVYGKSIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVAAVLKIQVHYYEDGNVQLVSHKDIQDSVQVSSDVQTAKEFIKIIENAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Protein binding
molecule keywords F-actin-capping protein subunit alpha-1
publication title Two distinct mechanisms for actin capping protein regulation--steric and allosteric inhibition
pubmed doi rcsb
source organism Gallus gallus
total genus 87
structure length 270
sequence length 270
ec nomenclature
pdb deposition date 2009-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01267 F-actin_cap_A F-actin capping protein alpha subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 3aa6A01
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 3aa6A02
3LK2B 3AA6B 1IZNA 2KXPA 3AAAA 3LK41 3AA0A 3AAEA 3LK3B 3AA7A 5AFUL 2KZ7A 3AA1A 5ADXK 4AKRB 1IZNB 3LK2A 3AA6A 2KXPB 3AAAB 3AA0B 3AAEB 5AFUK 3AA7B 3LK3A 2KZ7B 3AA1B 4AKRA 3LK42 5ADXL
chains in the Genus database with same CATH superfamily
3PGRA 1OPFA 3KVDD 2Y2XA 2R4LA 1MPFA 4JCHA 3NSGA 3T24A 3PRNA 5G38A 3SY9A 1ZHWA 4C4VB 2LHFA 4E1TA 1HXXA 5G26A 3PGSA 2O4DA 4FZLA 3A2SX 4GF4A 4O4UA 4GHBA 3BRZA 2ZLDA 3UU2A 3GP6A 1GU9A 5DIPA 4N58A 1G90A 4IL6O 5IYUA 4GCQA 3C5OA 2Y7SA 3NJTA 3AAEA 3SYSA 1BXWA 3LVYA 5DL7A 2AXTO 2O4VA 1QJ8A 4FZNA 3SY7A 4D5UA 5T5FA 3DZMA 5EE2A 2PFXA 4CTDA 4G76A 1S5LO 5JDPA 2FGRA 2OMFA 3K19A 4AKRB 2XTQA 1BT9A 3AAAB 1MM4A 3T20A 4AFKA 4QQ1A 2KZ7B 3A0HO 3LK2B 3SYBA 1IZNA 4AYNA 2R8AA 4K3BA 4AYDC 4KR4A 2N2LA 5ADXK 4D65A 5DL6A 3AA6A 3QRAA 3DWNA 2KC0A 4AUIA 1ZHTA 1P4TA 4N75A 4GCSA 2OYOA 4O4XA 4PUXA 4N59A 5B66O 2M06A 4AYID 4FSOA 5DIKA 2PRNA 4F4BA 4N74A 3LK3B 3WU2O 2LFUA 4LSEA 1IZNB 2XE5A 1HXTA 2QTKA 6PRNA 3AA0B 1YS5A 2XTRA 2M07A 1GFNA 5GTHO 2XG6A 1ZHZA 4O3WA 2J1NA 4O3XB 1T16A 4BUMX 2R4PA 2ERVA 2PORA 3V8UA 3A0BO 5AFUK 4RLBA 2JQYA 3VZTX 4FUVA 3PGUA 3C1LA 3WI4A 1OSMA 3HW9A 3JCUO 3HWBA 3VE1A 5TISO 3FYXA 5KAIO 2R88A 2Q0TA 3DWOX 2JN8A 2WVPA 2IJCA 2ODJA 5B5EO 4FMSA 4FOZA 3PQSA 3BS0A 2XMXA 2YPVA 1MM5A 1THQA 4RLCA 5G39A 4PJ0O 3SZDA 3AA7A 5AFUL 3AA1A 3KZIO 5GV0A 1E54A 3VZUX 3DA4A 1ZHYA 2AF7A 2FGQX 3AAEB 4RJXA 5H2FO 2Y0KA 2IWWA 3LK42 2KXPA 2F1TA 3LK41 3VE2A 4O3ZA 1KNCA 2Y0LA 2ES9A 4C69X 2F1VA 4U9CA 4G75A 1QJ9A 5G3AA 2N2MA 4LSIA 4KR8A 3D7IA 5DL5A 3BEYA 4C4VA 4XNLA 2F1CX 5D5DA 1Q9GA 4FESA 3SZVA 4GCPA 5DL8A 3UAQA 5FVNA 1ORMA 2QEUA 1GFMA 4FSPA 3T0SA 3G7GA 4O49A 1T1LA 5ADXL 4LSHA 3AA6B 2R4NA 4AZLA 2W81C 2WJRA 3BRYA 4AYMC 4O3YA 3HOLA 2MHLA 2W80C 8PRNA 4AYEC 2GE4A 3RBHA 4FRTA 2XE1A 1HXUA 2ZFGA 5GTIO 2WJQA 2K0LA 1Q9FA 4UB8O 4KRAA 3UPGA 2X9KA 4AKMA 1P8CA 4XNKA 4LSFA 2K4TA 4AKRA 3POQA 2IWVA 2R4OA 3AAAA 1BH3A 1ME5A 1GFPA 2KZ7A 3VZWX 1PRNA 4RL9A 4RJWA 4E1SA 1GFOA 5KAFO 3LK2A 2J4UP 2MNHA 1LW1A 4D64A 1GFQA 2YNKA 3TZGA 2XE3A 3VY9X 2CWQA 1H6S1 3QRCA 2GMYA 1ZHXA 2Y0HA 4FRXA 4JFBA 4Z3TA 4PR7A 2X27X 3JTYA 4K3CA 4B61A 1VKEA 3AA7B 3LK3A 2JMMA 3AA1B 3EMNX 3PQUA 3POXA 5E79O 5PRNA 3AA0A 4G9QA 1PHOA 3WI5A 1QJPA 2KXPB 3DA3A 3PORA 4FZMA 2XE2A 3POUA 2KDYA 4C00A 2OUWA 3VY8X 2R89A 4UB6O 4FQEA 4FT6A 3HOEA 3O0EA 3PF1A 7PRNA 2PRRA
chains in the Genus database with same CATH topology
1HXUA 3LK2B 3SYBA 2ZFGA 1IZNA 4AYNA 1OPFA 3KVDD 3SZDA 4AYDC 3AA7A 2Y2XA 5AFUL 4KR4A 2K0LA 2N2LA 3AA1A 5ADXK 5GV0A 1Q9FA 1MPFA 4JCHA 3NSGA 4D65A 1E54A 5DL6A 3PRNA 3T24A 3AA6A 3QRAA 3VZUX 2KC0A 4KRAA 3DA4A 1ZHYA 3UPGA 4AUIA 3SY9A 1ZHTA 1P4TA 2AF7A 1ZHWA 2FGQX 3AAEB 4AKMA 1P8CA 4XNKA 2LHFA 4GCSA 4LSFA 2OYOA 4O4XA 4PUXA 4RJXA 4N59A 2K4TA 4E1TA 2Y0KA 2M06A 4AKRA 1HXXA 3LK42 3POQA 5G26A 4AYID 4FSOA 5DIKA 2KXPA 3AAAA 2PRNA 2F1TA 1BH3A 1ME5A 3LK41 3VE2A 4O3ZA 4F4BA 1GFPA 1KNCA 2Y0LA 2O4DA 3LK3B 4FZLA 2KZ7A 3A2SX 4GF4A 2ES9A 1PRNA 3VZWX 4O4UA 4RL9A 4GHBA 4RJWA 2LFUA 4LSEA 4C69X 4E1SA 1GFOA 1IZNB 3LK2A 2XE5A 2J4UP 2MNHA 1LW1A 1HXTA 4D64A 2F1VA 2QTKA 2ZLDA 6PRNA 3UU2A 3AA0B 1YS5A 2XTRA 3GP6A 4U9CA 2M07A 1GU9A 1GFQA 5DIPA 2YNKA 4N58A 4G75A 3TZGA 1QJ9A 1GFNA 2XE3A 3VY9X 2CWQA 2N2MA 4LSIA 1H6S1 1G90A 2XG6A 3QRCA 5IYUA 4GCQA 4KR8A 3D7IA 5DL5A 3C5OA 2Y7SA 1ZHZA 2GMYA 1ZHXA 3BEYA 4O3WA 4XNLA 3AAEA 2J1NA 2Y0HA 4O3XB 1Q9GA 4FRXA 5D5DA 4FESA 4JFBA 4Z3TA 3SZVA 4GCPA 5DL8A 3SYSA 1BXWA 3LVYA 4BUMX 2ERVA 2PORA 2X27X 3UAQA 3JTYA 3V8UA 5FVNA 1ORMA 5DL7A 2QEUA 4B61A 5AFUK 1GFMA 4RLBA 1VKEA 3VZTX 3AA7B 3LK3A 2O4VA 1QJ8A 4FSPA 2JMMA 3T0SA 3AA1B 4FZNA 3SY7A 3EMNX 4FUVA 4D5UA 3C1LA 3G7GA 1OSMA 3HW9A 4O49A 3WI4A 3HWBA 3VE1A 5ADXL 4LSHA 3AA6B 5T5FA 3PQUA 4AZLA 3POXA 3FYXA 5EE2A 2PFXA 5PRNA 2W81C 3AA0A 2Q0TA 4G76A 2JN8A 4AYMC 4O3YA 2IJCA 2ODJA 3HOLA 4G9QA 5JDPA 2FGRA 2OMFA 2MHLA 4FMSA 1PHOA 4FOZA 3K19A 3PQSA 2W80C 4AKRB 2XTQA 3WI5A 1QJPA 1BT9A 2XMXA 2KXPB 8PRNA 3AAAB 1MM4A 2GE4A 3DA3A 3RBHA 3PORA 4FZMA 2YPVA 4AYEC 2XE2A 3T20A 3POUA 4FRTA 4AFKA 2KDYA 4QQ1A 2OUWA 2KZ7B 1MM5A 3VY8X 1THQA 4FT6A 3HOEA 3O0EA 7PRNA 2PRRA 4RLCA 2XE1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LK2 B;  3AA6 B;  1IZN A;  2KXP A;  3AAA A;  3LK4 1;  3AA0 A;  3AAE A;  3LK3 B;  3AA7 A;  5AFU L;  2KZ7 A;  3AA1 A;  5ADX K;  4AKR B;  1IZN B;  3LK2 A;  3AA6 A;  2KXP B;  3AAA B;  3AA0 B;  3AAE B;  5AFU K;  3AA7 B;  3LK3 A;  2KZ7 B;  3AA1 B;  4AKR A;  3LK4 2;  5ADX L; 
#chains in the Genus database with same CATH topology
 3PGR A;  1OPF A;  3KVD D;  2Y2X A;  2R4L A;  1MPF A;  4JCH A;  3NSG A;  3T24 A;  3PRN A;  5G38 A;  3SY9 A;  1ZHW A;  4C4V B;  2LHF A;  4E1T A;  1HXX A;  5G26 A;  3PGS A;  2O4D A;  4FZL A;  3A2S X;  4GF4 A;  4O4U A;  4GHB A;  3BRZ A;  2ZLD A;  3UU2 A;  3GP6 A;  1GU9 A;  5DIP A;  4N58 A;  1G90 A;  4IL6 O;  5IYU A;  4GCQ A;  3C5O A;  2Y7S A;  3NJT A;  3AAE A;  3SYS A;  1BXW A;  3LVY A;  5DL7 A;  2AXT O;  2O4V A;  1QJ8 A;  4FZN A;  3SY7 A;  4D5U A;  5T5F A;  3DZM A;  5EE2 A;  2PFX A;  4CTD A;  4G76 A;  1S5L O;  5JDP A;  2FGR A;  2OMF A;  3K19 A;  4AKR B;  2XTQ A;  1BT9 A;  3AAA B;  1MM4 A;  3T20 A;  4AFK A;  4QQ1 A;  2KZ7 B;  3A0H O;  3LK2 B;  3SYB A;  1IZN A;  4AYN A;  2R8A A;  4K3B A;  4AYD C;  4KR4 A;  2N2L A;  5ADX K;  4D65 A;  5DL6 A;  3AA6 A;  3QRA A;  3DWN A;  2KC0 A;  4AUI A;  1ZHT A;  1P4T A;  4N75 A;  4GCS A;  2OYO A;  4O4X A;  4PUX A;  4N59 A;  5B66 O;  2M06 A;  4AYI D;  4FSO A;  5DIK A;  2PRN A;  4F4B A;  4N74 A;  3LK3 B;  3WU2 O;  2LFU A;  4LSE A;  1IZN B;  2XE5 A;  1HXT A;  2QTK A;  6PRN A;  3AA0 B;  1YS5 A;  2XTR A;  2M07 A;  1GFN A;  5GTH O;  2XG6 A;  1ZHZ A;  4O3W A;  2J1N A;  4O3X B;  1T16 A;  4BUM X;  2R4P A;  2ERV A;  2POR A;  3V8U A;  3A0B O;  5AFU K;  4RLB A;  2JQY A;  3VZT X;  4FUV A;  3PGU A;  3C1L A;  3WI4 A;  1OSM A;  3HW9 A;  3JCU O;  3HWB A;  3VE1 A;  5TIS O;  3FYX A;  5KAI O;  2R88 A;  2Q0T A;  3DWO X;  2JN8 A;  2WVP A;  2IJC A;  2ODJ A;  5B5E O;  4FMS A;  4FOZ A;  3PQS A;  3BS0 A;  2XMX A;  2YPV A;  1MM5 A;  1THQ A;  4RLC A;  5G39 A;  4PJ0 O;  3SZD A;  3AA7 A;  5AFU L;  3AA1 A;  3KZI O;  5GV0 A;  1E54 A;  3VZU X;  3DA4 A;  1ZHY A;  2AF7 A;  2FGQ X;  3AAE B;  4RJX A;  5H2F O;  2Y0K A;  2IWW A;  3LK4 2;  2KXP A;  2F1T A;  3LK4 1;  3VE2 A;  4O3Z A;  1KNC A;  2Y0L A;  2ES9 A;  4C69 X;  2F1V A;  4U9C A;  4G75 A;  1QJ9 A;  5G3A A;  2N2M A;  4LSI A;  4KR8 A;  3D7I A;  5DL5 A;  3BEY A;  4C4V A;  4XNL A;  2F1C X;  5D5D A;  1Q9G A;  4FES A;  3SZV A;  4GCP A;  5DL8 A;  3UAQ A;  5FVN A;  1ORM A;  2QEU A;  1GFM A;  4FSP A;  3T0S A;  3G7G A;  4O49 A;  1T1L A;  5ADX L;  4LSH A;  3AA6 B;  2R4N A;  4AZL A;  2W81 C;  2WJR A;  3BRY A;  4AYM C;  4O3Y A;  3HOL A;  2MHL A;  2W80 C;  8PRN A;  4AYE C;  2GE4 A;  3RBH A;  4FRT A;  2XE1 A;  1HXU A;  2ZFG A;  5GTI O;  2WJQ A;  2K0L A;  1Q9F A;  4UB8 O;  4KRA A;  3UPG A;  2X9K A;  4AKM A;  1P8C A;  4XNK A;  4LSF A;  2K4T A;  4AKR A;  3POQ A;  2IWV A;  2R4O A;  3AAA A;  1BH3 A;  1ME5 A;  1GFP A;  2KZ7 A;  3VZW X;  1PRN A;  4RL9 A;  4RJW A;  4E1S A;  1GFO A;  5KAF O;  3LK2 A;  2J4U P;  2MNH A;  1LW1 A;  4D64 A;  1GFQ A;  2YNK A;  3TZG A;  2XE3 A;  3VY9 X;  2CWQ A;  1H6S 1;  3QRC A;  2GMY A;  1ZHX A;  2Y0H A;  4FRX A;  4JFB A;  4Z3T A;  4PR7 A;  2X27 X;  3JTY A;  4K3C A;  4B61 A;  1VKE A;  3AA7 B;  3LK3 A;  2JMM A;  3AA1 B;  3EMN X;  3PQU A;  3POX A;  5E79 O;  5PRN A;  3AA0 A;  4G9Q A;  1PHO A;  3WI5 A;  1QJP A;  2KXP B;  3DA3 A;  3POR A;  4FZM A;  2XE2 A;  3POU A;  2KDY A;  4C00 A;  2OUW A;  3VY8 X;  2R89 A;  4UB6 O;  4FQE A;  4FT6 A;  3HOE A;  3O0E A;  3PF1 A;  7PRN A;  2PRR A; 
#chains in the Genus database with same CATH homology
 1HXU A;  3LK2 B;  3SYB A;  2ZFG A;  1IZN A;  4AYN A;  1OPF A;  3KVD D;  3SZD A;  4AYD C;  3AA7 A;  2Y2X A;  5AFU L;  4KR4 A;  2K0L A;  2N2L A;  3AA1 A;  5ADX K;  5GV0 A;  1Q9F A;  1MPF A;  4JCH A;  3NSG A;  4D65 A;  1E54 A;  5DL6 A;  3PRN A;  3T24 A;  3AA6 A;  3QRA A;  3VZU X;  2KC0 A;  4KRA A;  3DA4 A;  1ZHY A;  3UPG A;  4AUI A;  3SY9 A;  1ZHT A;  1P4T A;  2AF7 A;  1ZHW A;  2FGQ X;  3AAE B;  4AKM A;  1P8C A;  4XNK A;  2LHF A;  4GCS A;  4LSF A;  2OYO A;  4O4X A;  4PUX A;  4RJX A;  4N59 A;  2K4T A;  4E1T A;  2Y0K A;  2M06 A;  4AKR A;  1HXX A;  3LK4 2;  3POQ A;  5G26 A;  4AYI D;  4FSO A;  5DIK A;  2KXP A;  3AAA A;  2PRN A;  2F1T A;  1BH3 A;  1ME5 A;  3LK4 1;  3VE2 A;  4O3Z A;  4F4B A;  1GFP A;  1KNC A;  2Y0L A;  2O4D A;  3LK3 B;  4FZL A;  2KZ7 A;  3A2S X;  4GF4 A;  2ES9 A;  1PRN A;  3VZW X;  4O4U A;  4RL9 A;  4GHB A;  4RJW A;  2LFU A;  4LSE A;  4C69 X;  4E1S A;  1GFO A;  1IZN B;  3LK2 A;  2XE5 A;  2J4U P;  2MNH A;  1LW1 A;  1HXT A;  4D64 A;  2F1V A;  2QTK A;  2ZLD A;  6PRN A;  3UU2 A;  3AA0 B;  1YS5 A;  2XTR A;  3GP6 A;  4U9C A;  2M07 A;  1GU9 A;  1GFQ A;  5DIP A;  2YNK A;  4N58 A;  4G75 A;  3TZG A;  1QJ9 A;  1GFN A;  2XE3 A;  3VY9 X;  2CWQ A;  2N2M A;  4LSI A;  1H6S 1;  1G90 A;  2XG6 A;  3QRC A;  5IYU A;  4GCQ A;  4KR8 A;  3D7I A;  5DL5 A;  3C5O A;  2Y7S A;  1ZHZ A;  2GMY A;  1ZHX A;  3BEY A;  4O3W A;  4XNL A;  3AAE A;  2J1N A;  2Y0H A;  4O3X B;  1Q9G A;  4FRX A;  5D5D A;  4FES A;  4JFB A;  4Z3T A;  3SZV A;  4GCP A;  5DL8 A;  3SYS A;  1BXW A;  3LVY A;  4BUM X;  2ERV A;  2POR A;  2X27 X;  3UAQ A;  3JTY A;  3V8U A;  5FVN A;  1ORM A;  5DL7 A;  2QEU A;  4B61 A;  5AFU K;  1GFM A;  4RLB A;  1VKE A;  3VZT X;  3AA7 B;  3LK3 A;  2O4V A;  1QJ8 A;  4FSP A;  2JMM A;  3T0S A;  3AA1 B;  4FZN A;  3SY7 A;  3EMN X;  4FUV A;  4D5U A;  3C1L A;  3G7G A;  1OSM A;  3HW9 A;  4O49 A;  3WI4 A;  3HWB A;  3VE1 A;  5ADX L;  4LSH A;  3AA6 B;  5T5F A;  3PQU A;  4AZL A;  3POX A;  3FYX A;  5EE2 A;  2PFX A;  5PRN A;  2W81 C;  3AA0 A;  2Q0T A;  4G76 A;  2JN8 A;  4AYM C;  4O3Y A;  2IJC A;  2ODJ A;  3HOL A;  4G9Q A;  5JDP A;  2FGR A;  2OMF A;  2MHL A;  4FMS A;  1PHO A;  4FOZ A;  3K19 A;  3PQS A;  2W80 C;  4AKR B;  2XTQ A;  3WI5 A;  1QJP A;  1BT9 A;  2XMX A;  2KXP B;  8PRN A;  3AAA B;  1MM4 A;  2GE4 A;  3DA3 A;  3RBH A;  3POR A;  4FZM A;  2YPV A;  4AYE C;  2XE2 A;  3T20 A;  3POU A;  4FRT A;  4AFK A;  2KDY A;  4QQ1 A;  2OUW A;  2KZ7 B;  1MM5 A;  3VY8 X;  1THQ A;  4FT6 A;  3HOE A;  3O0E A;  7PRN A;  2PRR A;  4RLC A;  2XE1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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