1YI2W

Crystal structure of erythromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 49

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
EMPTYS1 (2-6)TII2 (28-31)TII1 (10-13)AH1 (15-24)AH2 (39-48)S2 (31-35)S4 (115-117)TI1 (48-51)S3 (52-55)AH3 (59-69)AH6 (143-153)TI3 (108-111)TVIII1 (72-75)AH4 (81-86)AH5 (93-102)TI2 (107-110)TIV2 (106-109)TII3 (121-124)3H1 (132-134)TIV3 (127-130)S5 (139-140)Updating...
connected with : NaN
molecule tags Ribosome
publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule keywords 23S Ribosomal RNA
total genus 49
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2005-01-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 1yi2W02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 1yi2W01
3PIOW 1W2BV 2OTJW 4WFAW 1KQSV 3CCLW 4U67W 2ZJRW 1YITW 3CCUW 4IO9W 3J7ZZ 3CCRW 1KD1X 3CCMW 1VQOW 4WFNW 1VQ9W 3CCVW 1YHQW 3CC4W 1Q81X 3CCSW 3CF5W 5JVGW 4IOCW 1S72W 4WFBW 3CCQW 1JJ2V 1QVGV 1Q7YX 2ZJPW 1M1KX 5HL7W 5JVHW 1VQ5W 1VQMW 3CC2W 3I55W 1YJWW 5GAGa 3I56W 1M90X 2QA4W 5GADa 3CC7W 5GAEa 1VQ6W 3CD6W 5GAHa 4WF9W 1K73X 1YIJW 1K8AX 2QEXW 3CCEW 1KC8X 3CMEW 1YI2W 1YJ9W 1Q86X 1VQNW 1N8RX 3CPWV 5DM6W 4WCEW 1VQPW 1BXYA 1VQ7W 1VQ8W 1QVFV 1VQKW 3CCJW 2ZJQW 4UY8Z 1YJNW 3G6EW 1NJIX 3OW2V 1Q82X 1VQLW 5DM7W 3CXCV 1VQ4W 2OTLW 4IOAW 3DLLW 3G71W 3G4SW 3CMAW 1K9MX 3PIPW
chains in the Genus database with same CATH superfamily
4C1NA 1MWTA 3PIOW 4YJMA 1W2BV 1RQVA 3W7TA 2OTJW 4WFAW 3O2OA 1KQSV 3CCLW 4U67W 2ZJRW 1YITW 3W7WA 3CCUW 3D3IA 1VQQA 4IO9W 1MBVB 3GQ0A 3W7XA 3O1FB 3J7ZZ 3CCRW 1KD1X 3CCMW 1VQOW 4WFNW 1VQ9W 3CCVW 1YHQW 3CC4W 1Q81X 4DKIA 1MWSA 4YKAA 3CCSW 5M18A 3CF5W 5JVGW 4IOCW 1S72W 4WFBW 3CCQW 1JJ2V 1QVGV 3G1BA 1Q7YX 2ZJPW 3GW1A 1M1KX 3O1FA 5M19A 5CA3A 5HL7W 1RQSA 4BL2A 5JVHW 4CPKA 1VQ5W 2WA9A 1VQMW 4YJXA 3CC2W 5GW7A 3I55W 2W9RA 4BL3A 1YJWW 5GAGa 3I56W 1R6QC 1M90X 2QA4W 5GADa 3CC7W 1MWUA 5GAEa 1VQ6W 3CD6W 1R6OC 1DD4A 5GAHa 4WF9W 3W7SA 1K73X 3ZG0A 1YIJW 3G3PA 3GQ1A 1K8AX 2QEXW 3CCEW 1KC8X 3CMEW 1YI2W 1YJ9W 1Q86X 1VQNW 3O2BA 2WA8A 1N8RX 3CPWV 3G19A 5DM6W 3W7UA 4WCEW 1VQPW 1BXYA 1VQ7W 1VQ8W 1QVFV 1VQKW 3CCJW 2ZJQW 4UY8Z 1LZWA 1YJNW 3ZFZA 3G6EW 1MBXC 1MG9A 1NJIX 3OW2V 1MBUC 1Q82X 1DD3A 1VQLW 5DM7W 3CXCV 3O2HA 1VQ4W 2OTLW 4IOAW 5M1AA 3DNJA 1MWRA 3ZG5A 3DLLW 3G71W 3G4SW 3CMAW 1CTFA 1RQUA 4CJNA 1K9MX 3PIPW
chains in the Genus database with same CATH topology
4C1NA 3PIOW 1W2BV 2OTJW 4WFAW 1KQSV 3CCLW 4U67W 2ZJRW 1YITW 3CCUW 4IO9W 3J7ZZ 3CCRW 1KD1X 3CCMW 1VQOW 4WFNW 1VQ9W 3CCVW 1YHQW 3CC4W 1Q81X 3CCSW 3CF5W 5JVGW 4IOCW 1S72W 4WFBW 3CCQW 1JJ2V 1QVGV 1Q7YX 2ZJPW 1M1KX 5HL7W 5JVHW 1VQ5W 1VQMW 3CC2W 3I55W 1YJWW 5GAGa 3I56W 1M90X 2QA4W 5GADa 3CC7W 5GAEa 1VQ6W 3CD6W 5GAHa 4WF9W 1K73X 1YIJW 1K8AX 2QEXW 3CCEW 1KC8X 3CMEW 1YI2W 1YJ9W 1Q86X 1VQNW 1N8RX 3CPWV 5DM6W 4WCEW 1VQPW 1BXYA 1VQ7W 1VQ8W 1QVFV 1VQKW 3CCJW 2ZJQW 4UY8Z 1YJNW 3G6EW 1NJIX 3OW2V 1Q82X 1VQLW 5DM7W 3CXCV 1VQ4W 2OTLW 4IOAW 3DLLW 3G71W 3G4SW 3CMAW 1K9MX 3PIPW
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3PIO W;  1W2B V;  2OTJ W;  4WFA W;  1KQS V;  3CCL W;  4U67 W;  2ZJR W;  1YIT W;  3CCU W;  4IO9 W;  3J7Z Z;  3CCR W;  1KD1 X;  3CCM W;  1VQO W;  4WFN W;  1VQ9 W;  3CCV W;  1YHQ W;  3CC4 W;  1Q81 X;  3CCS W;  3CF5 W;  5JVG W;  4IOC W;  1S72 W;  4WFB W;  3CCQ W;  1JJ2 V;  1QVG V;  1Q7Y X;  2ZJP W;  1M1K X;  5HL7 W;  5JVH W;  1VQ5 W;  1VQM W;  3CC2 W;  3I55 W;  1YJW W;  5GAG a;  3I56 W;  1M90 X;  2QA4 W;  5GAD a;  3CC7 W;  5GAE a;  1VQ6 W;  3CD6 W;  5GAH a;  4WF9 W;  1K73 X;  1YIJ W;  1K8A X;  2QEX W;  3CCE W;  1KC8 X;  3CME W;  1YI2 W;  1YJ9 W;  1Q86 X;  1VQN W;  1N8R X;  3CPW V;  5DM6 W;  4WCE W;  1VQP W;  1BXY A;  1VQ7 W;  1VQ8 W;  1QVF V;  1VQK W;  3CCJ W;  2ZJQ W;  4UY8 Z;  1YJN W;  3G6E W;  1NJI X;  3OW2 V;  1Q82 X;  1VQL W;  5DM7 W;  3CXC V;  1VQ4 W;  2OTL W;  4IOA W;  3DLL W;  3G71 W;  3G4S W;  3CMA W;  1K9M X;  3PIP W; 
#chains in the Genus database with same CATH topology
 4C1N A;  1MWT A;  3PIO W;  4YJM A;  1W2B V;  1RQV A;  3W7T A;  2OTJ W;  4WFA W;  3O2O A;  1KQS V;  3CCL W;  4U67 W;  2ZJR W;  1YIT W;  3W7W A;  3CCU W;  3D3I A;  1VQQ A;  4IO9 W;  1MBV B;  3GQ0 A;  3W7X A;  3O1F B;  3J7Z Z;  3CCR W;  1KD1 X;  3CCM W;  1VQO W;  4WFN W;  1VQ9 W;  3CCV W;  1YHQ W;  3CC4 W;  1Q81 X;  4DKI A;  1MWS A;  4YKA A;  3CCS W;  5M18 A;  3CF5 W;  5JVG W;  4IOC W;  1S72 W;  4WFB W;  3CCQ W;  1JJ2 V;  1QVG V;  3G1B A;  1Q7Y X;  2ZJP W;  3GW1 A;  1M1K X;  3O1F A;  5M19 A;  5CA3 A;  5HL7 W;  1RQS A;  4BL2 A;  5JVH W;  4CPK A;  1VQ5 W;  2WA9 A;  1VQM W;  4YJX A;  3CC2 W;  5GW7 A;  3I55 W;  2W9R A;  4BL3 A;  1YJW W;  5GAG a;  3I56 W;  1R6Q C;  1M90 X;  2QA4 W;  5GAD a;  3CC7 W;  1MWU A;  5GAE a;  1VQ6 W;  3CD6 W;  1R6O C;  1DD4 A;  5GAH a;  4WF9 W;  3W7S A;  1K73 X;  3ZG0 A;  1YIJ W;  3G3P A;  3GQ1 A;  1K8A X;  2QEX W;  3CCE W;  1KC8 X;  3CME W;  1YI2 W;  1YJ9 W;  1Q86 X;  1VQN W;  3O2B A;  2WA8 A;  1N8R X;  3CPW V;  3G19 A;  5DM6 W;  3W7U A;  4WCE W;  1VQP W;  1BXY A;  1VQ7 W;  1VQ8 W;  1QVF V;  1VQK W;  3CCJ W;  2ZJQ W;  4UY8 Z;  1LZW A;  1YJN W;  3ZFZ A;  3G6E W;  1MBX C;  1MG9 A;  1NJI X;  3OW2 V;  1MBU C;  1Q82 X;  1DD3 A;  1VQL W;  5DM7 W;  3CXC V;  3O2H A;  1VQ4 W;  2OTL W;  4IOA W;  5M1A A;  3DNJ A;  1MWR A;  3ZG5 A;  3DLL W;  3G71 W;  3G4S W;  3CMA W;  1CTF A;  1RQU A;  4CJN A;  1K9M X;  3PIP W; 
#chains in the Genus database with same CATH homology
 4C1N A;  3PIO W;  1W2B V;  2OTJ W;  4WFA W;  1KQS V;  3CCL W;  4U67 W;  2ZJR W;  1YIT W;  3CCU W;  4IO9 W;  3J7Z Z;  3CCR W;  1KD1 X;  3CCM W;  1VQO W;  4WFN W;  1VQ9 W;  3CCV W;  1YHQ W;  3CC4 W;  1Q81 X;  3CCS W;  3CF5 W;  5JVG W;  4IOC W;  1S72 W;  4WFB W;  3CCQ W;  1JJ2 V;  1QVG V;  1Q7Y X;  2ZJP W;  1M1K X;  5HL7 W;  5JVH W;  1VQ5 W;  1VQM W;  3CC2 W;  3I55 W;  1YJW W;  5GAG a;  3I56 W;  1M90 X;  2QA4 W;  5GAD a;  3CC7 W;  5GAE a;  1VQ6 W;  3CD6 W;  5GAH a;  4WF9 W;  1K73 X;  1YIJ W;  1K8A X;  2QEX W;  3CCE W;  1KC8 X;  3CME W;  1YI2 W;  1YJ9 W;  1Q86 X;  1VQN W;  1N8R X;  3CPW V;  5DM6 W;  4WCE W;  1VQP W;  1BXY A;  1VQ7 W;  1VQ8 W;  1QVF V;  1VQK W;  3CCJ W;  2ZJQ W;  4UY8 Z;  1YJN W;  3G6E W;  1NJI X;  3OW2 V;  1Q82 X;  1VQL W;  5DM7 W;  3CXC V;  1VQ4 W;  2OTL W;  4IOA W;  3DLL W;  3G71 W;  3G4S W;  3CMA W;  1K9M X;  3PIP W;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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