1YIJW

Crystal structure of telithromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 49
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2005-01-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 1yijW02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 1yijW01
3CMEW 3CCJW 3I55W 3PIPW 5GADa 4IO9W 1KC8X 2QA4W 1Q81X 5GAHa 3CCEW 4UY8Z 5DM7W 4WF9W 1QVFV 1BXYA 3CCRW 4WFBW 1KD1X 2OTLW 1K73X 1VQ9W 3DLLW 3OW2V 1YITW 3CC4W 2QEXW 4WFAW 1S72W 1Q7YX 1YJ9W 1YHQW 3CCMW 3CMAW 2OTJW 3CC2W 1W2BV 2ZJPW 1K8AX 1NJIX 5JVHW 3CXCV 5GAGa 3CCLW 1YJWW 1VQKW 1YIJW 1VQOW 1YI2W 5JVGW 4U67W 1K9MX 3PIOW 1VQNW 2ZJRW 2ZJQW 3I56W 3J7ZZ 1VQLW 4WCEW 1VQ5W 4IOAW 1VQ6W 3G4SW 1Q86X 1YJNW 1KQSV 3CC7W 5HL7W 3CCUW 1N8RX 1QVGV 1VQ4W 3CCSW 1Q82X 3G6EW 4IOCW 3CCQW 4WFNW 3G71W 1VQPW 1JJ2V 1M1KX 3CD6W 3CPWV 5GAEa 1M90X 3CCVW 1VQ7W 3CF5W 5DM6W 1VQMW 1VQ8W
chains in the Genus database with same CATH superfamily
3CMEW 3CCJW 1MWTA 3I55W 4CJNA 3PIPW 4C1NA 5GW7A 1VQQA 5GADa 1MBXC 4IO9W 1KC8X 3O2BA 2QA4W 3ZFZA 4BL2A 1Q81X 5GAHa 1RQUA 1LZWA 3CCEW 4UY8Z 1R6QC 3W7SA 5DM7W 1MBUC 3W7UA 1QVFV 4WF9W 1BXYA 3CCRW 4WFBW 1KD1X 2OTLW 1K73X 1MWUA 2WA9A 1VQ9W 3DLLW 3OW2V 1YITW 3O2HA 3CC4W 2QEXW 2W9RA 4WFAW 3W7TA 1S72W 3D3IA 4YJMA 3G19A 1Q7YX 1YJ9W 5CA3A 1YHQW 1DD4A 1RQVA 3CCMW 1DD3A 4CPKA 3CMAW 2WA8A 2OTJW 3CC2W 1W2BV 3W7XA 1K8AX 1R6OC 1NJIX 2ZJPW 3O1FA 5JVHW 3CXCV 5GAGa 3CF5W 1MBVB 3CCLW 1YJWW 1VQKW 1MWSA 5M19A 1YIJW 1VQOW 1YI2W 3O1FB 3W7WA 3GQ0A 5JVGW 3O2OA 4U67W 1K9MX 3ZG0A 3PIOW 1VQNW 4YKAA 2ZJRW 4YJXA 3G3PA 3I56W 2ZJQW 4DKIA 3J7ZZ 1VQLW 4WCEW 3GQ1A 1VQ5W 4IOAW 1VQ6W 3G4SW 1MWRA 3GW1A 1Q86X 1YJNW 1KQSV 3CC7W 3DNJA 5HL7W 1MG9A 3CCUW 1N8RX 1QVGV 1VQ4W 3ZG5A 3CCSW 1Q82X 3G6EW 1CTFA 4IOCW 3CCQW 4WFNW 4BL3A 3G1BA 3G71W 1VQPW 1JJ2V 1M1KX 3CD6W 3CPWV 1RQSA 5GAEa 1M90X 3CCVW 1VQ7W 5M18A 5M1AA 5DM6W 1VQMW 1VQ8W
chains in the Genus database with same CATH topology
3CMEW 3CCJW 3I55W 3PIPW 4C1NA 5GADa 4IO9W 1KC8X 2QA4W 1Q81X 5GAHa 3CCEW 4UY8Z 5DM7W 4WF9W 1QVFV 1BXYA 3CCRW 4WFBW 1KD1X 2OTLW 1K73X 1VQ9W 3DLLW 3OW2V 1YITW 3CC4W 2QEXW 4WFAW 1S72W 1Q7YX 1YJ9W 1YHQW 3CCMW 3CMAW 2OTJW 3CC2W 1W2BV 2ZJPW 1K8AX 1NJIX 5JVHW 3CXCV 5GAGa 3CCLW 1YJWW 1VQKW 1YIJW 1VQOW 1YI2W 5JVGW 4U67W 1K9MX 3PIOW 1VQNW 2ZJRW 2ZJQW 3I56W 3J7ZZ 1VQLW 4WCEW 1VQ5W 4IOAW 1VQ6W 3G4SW 1Q86X 1YJNW 1KQSV 3CC7W 5HL7W 3CCUW 1N8RX 1QVGV 1VQ4W 3CCSW 1Q82X 3G6EW 4IOCW 3CCQW 4WFNW 3G71W 1VQPW 1JJ2V 1M1KX 3CD6W 3CPWV 5GAEa 1M90X 3CCVW 1VQ7W 3CF5W 5DM6W 1VQMW 1VQ8W
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CME W;  3CCJ W;  3I55 W;  3PIP W;  5GAD a;  4IO9 W;  1KC8 X;  2QA4 W;  1Q81 X;  5GAH a;  3CCE W;  4UY8 Z;  5DM7 W;  4WF9 W;  1QVF V;  1BXY A;  3CCR W;  4WFB W;  1KD1 X;  2OTL W;  1K73 X;  1VQ9 W;  3DLL W;  3OW2 V;  1YIT W;  3CC4 W;  2QEX W;  4WFA W;  1S72 W;  1Q7Y X;  1YJ9 W;  1YHQ W;  3CCM W;  3CMA W;  2OTJ W;  3CC2 W;  1W2B V;  2ZJP W;  1K8A X;  1NJI X;  5JVH W;  3CXC V;  5GAG a;  3CCL W;  1YJW W;  1VQK W;  1YIJ W;  1VQO W;  1YI2 W;  5JVG W;  4U67 W;  1K9M X;  3PIO W;  1VQN W;  2ZJR W;  2ZJQ W;  3I56 W;  3J7Z Z;  1VQL W;  4WCE W;  1VQ5 W;  4IOA W;  1VQ6 W;  3G4S W;  1Q86 X;  1YJN W;  1KQS V;  3CC7 W;  5HL7 W;  3CCU W;  1N8R X;  1QVG V;  1VQ4 W;  3CCS W;  1Q82 X;  3G6E W;  4IOC W;  3CCQ W;  4WFN W;  3G71 W;  1VQP W;  1JJ2 V;  1M1K X;  3CD6 W;  3CPW V;  5GAE a;  1M90 X;  3CCV W;  1VQ7 W;  3CF5 W;  5DM6 W;  1VQM W;  1VQ8 W; 
#chains in the Genus database with same CATH topology
 3CME W;  3CCJ W;  1MWT A;  3I55 W;  4CJN A;  3PIP W;  4C1N A;  5GW7 A;  1VQQ A;  5GAD a;  1MBX C;  4IO9 W;  1KC8 X;  3O2B A;  2QA4 W;  3ZFZ A;  4BL2 A;  1Q81 X;  5GAH a;  1RQU A;  1LZW A;  3CCE W;  4UY8 Z;  1R6Q C;  3W7S A;  5DM7 W;  1MBU C;  3W7U A;  1QVF V;  4WF9 W;  1BXY A;  3CCR W;  4WFB W;  1KD1 X;  2OTL W;  1K73 X;  1MWU A;  2WA9 A;  1VQ9 W;  3DLL W;  3OW2 V;  1YIT W;  3O2H A;  3CC4 W;  2QEX W;  2W9R A;  4WFA W;  3W7T A;  1S72 W;  3D3I A;  4YJM A;  3G19 A;  1Q7Y X;  1YJ9 W;  5CA3 A;  1YHQ W;  1DD4 A;  1RQV A;  3CCM W;  1DD3 A;  4CPK A;  3CMA W;  2WA8 A;  2OTJ W;  3CC2 W;  1W2B V;  3W7X A;  1K8A X;  1R6O C;  1NJI X;  2ZJP W;  3O1F A;  5JVH W;  3CXC V;  5GAG a;  3CF5 W;  1MBV B;  3CCL W;  1YJW W;  1VQK W;  1MWS A;  5M19 A;  1YIJ W;  1VQO W;  1YI2 W;  3O1F B;  3W7W A;  3GQ0 A;  5JVG W;  3O2O A;  4U67 W;  1K9M X;  3ZG0 A;  3PIO W;  1VQN W;  4YKA A;  2ZJR W;  4YJX A;  3G3P A;  3I56 W;  2ZJQ W;  4DKI A;  3J7Z Z;  1VQL W;  4WCE W;  3GQ1 A;  1VQ5 W;  4IOA W;  1VQ6 W;  3G4S W;  1MWR A;  3GW1 A;  1Q86 X;  1YJN W;  1KQS V;  3CC7 W;  3DNJ A;  5HL7 W;  1MG9 A;  3CCU W;  1N8R X;  1QVG V;  1VQ4 W;  3ZG5 A;  3CCS W;  1Q82 X;  3G6E W;  1CTF A;  4IOC W;  3CCQ W;  4WFN W;  4BL3 A;  3G1B A;  3G71 W;  1VQP W;  1JJ2 V;  1M1K X;  3CD6 W;  3CPW V;  1RQS A;  5GAE a;  1M90 X;  3CCV W;  1VQ7 W;  5M18 A;  5M1A A;  5DM6 W;  1VQM W;  1VQ8 W; 
#chains in the Genus database with same CATH homology
 3CME W;  3CCJ W;  3I55 W;  3PIP W;  4C1N A;  5GAD a;  4IO9 W;  1KC8 X;  2QA4 W;  1Q81 X;  5GAH a;  3CCE W;  4UY8 Z;  5DM7 W;  4WF9 W;  1QVF V;  1BXY A;  3CCR W;  4WFB W;  1KD1 X;  2OTL W;  1K73 X;  1VQ9 W;  3DLL W;  3OW2 V;  1YIT W;  3CC4 W;  2QEX W;  4WFA W;  1S72 W;  1Q7Y X;  1YJ9 W;  1YHQ W;  3CCM W;  3CMA W;  2OTJ W;  3CC2 W;  1W2B V;  2ZJP W;  1K8A X;  1NJI X;  5JVH W;  3CXC V;  5GAG a;  3CCL W;  1YJW W;  1VQK W;  1YIJ W;  1VQO W;  1YI2 W;  5JVG W;  4U67 W;  1K9M X;  3PIO W;  1VQN W;  2ZJR W;  2ZJQ W;  3I56 W;  3J7Z Z;  1VQL W;  4WCE W;  1VQ5 W;  4IOA W;  1VQ6 W;  3G4S W;  1Q86 X;  1YJN W;  1KQS V;  3CC7 W;  5HL7 W;  3CCU W;  1N8R X;  1QVG V;  1VQ4 W;  3CCS W;  1Q82 X;  3G6E W;  4IOC W;  3CCQ W;  4WFN W;  3G71 W;  1VQP W;  1JJ2 V;  1M1K X;  3CD6 W;  3CPW V;  5GAE a;  1M90 X;  3CCV W;  1VQ7 W;  3CF5 W;  5DM6 W;  1VQM W;  1VQ8 W; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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