1YJNW

Crystal structure of clindamycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 45
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2005-01-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 1yjnW02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 1yjnW01
5GADa 1K8AX 4IOAW 5GAGa 1VQ5W 2OTLW 5JVHW 4WF9W 3CD6W 5DM6W 3CC7W 1M1KX 4WCEW 1YJWW 1K9MX 1M90X 2OTJW 3CCMW 1KQSV 3CMEW 1Q82X 3PIOW 1VQLW 3I56W 3CCQW 3CCSW 3DLLW 3G71W 1S72W 3PIPW 1VQKW 4U67W 5GAEa 4IO9W 1N8RX 1YJ9W 5DM7W 1VQPW 3CF5W 1VQ6W 2QEXW 1K73X 4WFAW 1YJNW 1VQ4W 2ZJQW 4UY8Z 3CMAW 1VQ9W 3CCEW 1YIJW 1VQNW 1YITW 3CC2W 2QA4W 1KC8X 1NJIX 1YHQW 5JVGW 5HL7W 3CCVW 1Q81X 3CC4W 3CCUW 1Q7YX 1W2BV 3J7ZZ 1KD1X 3CCRW 3G4SW 3CXCV 3CCJW 3OW2V 1JJ2V 1QVGV 1VQMW 1Q86X 3I55W 3CCLW 1BXYA 3CPWV 4WFBW 1YI2W 3G6EW 1VQOW 4WFNW 1QVFV 4IOCW 1VQ7W 2ZJRW 5GAHa 2ZJPW 1VQ8W
chains in the Genus database with same CATH superfamily
5GADa 1K8AX 4IOAW 3O2HA 5GAGa 1VQ5W 1MG9A 4YJXA 2OTLW 4DKIA 5JVHW 4CPKA 4WF9W 3W7UA 3CD6W 1RQVA 5DM6W 3CC7W 3GW1A 3W7TA 1M1KX 4WCEW 1YJWW 1K9MX 1M90X 2OTJW 3ZFZA 1MBUC 3CCMW 1KQSV 3CMEW 1Q82X 5GW7A 3PIOW 3W7WA 1VQLW 3I56W 3CCQW 3CCSW 1R6QC 3DLLW 2W9RA 3G71W 1S72W 5M18A 3PIPW 1VQKW 4U67W 5GAEa 4IO9W 1MWRA 4C1NA 1N8RX 1YJ9W 5DM7W 1MBXC 1VQPW 3CF5W 1VQ6W 3O2OA 2QEXW 1K73X 3G19A 4WFAW 1YJNW 1VQ4W 2ZJQW 4UY8Z 3CMAW 3GQ1A 1VQ9W 3CCEW 1YIJW 1VQNW 1RQUA 3O1FB 4CJNA 1YITW 3CC2W 2QA4W 1KC8X 1NJIX 1YHQW 1LZWA 3O2BA 5JVGW 5HL7W 3G3PA 3CCVW 3D3IA 3GQ0A 2WA8A 1MBVB 1Q81X 1MWSA 3CC4W 3CCUW 3W7XA 1Q7YX 1W2BV 3J7ZZ 1KD1X 3CCRW 4YJMA 1MWTA 3G4SW 3CXCV 3CCJW 3OW2V 1JJ2V 3ZG5A 1QVGV 1VQMW 5M1AA 5M19A 1Q86X 3I55W 3CCLW 1DD4A 3ZG0A 1BXYA 3CPWV 4BL3A 4WFBW 1YI2W 3G6EW 1VQOW 5CA3A 4WFNW 3W7SA 1R6OC 4YKAA 1QVFV 4IOCW 1VQ7W 2ZJRW 5GAHa 1VQQA 1DD3A 3O1FA 2ZJPW 1CTFA 4BL2A 1RQSA 1VQ8W 3G1BA 2WA9A 3DNJA 1MWUA
chains in the Genus database with same CATH topology
5GADa 1K8AX 4IOAW 5GAGa 1VQ5W 2OTLW 5JVHW 4WF9W 3CD6W 5DM6W 3CC7W 1M1KX 4WCEW 1YJWW 1K9MX 1M90X 2OTJW 3CCMW 1KQSV 3CMEW 1Q82X 3PIOW 1VQLW 3I56W 3CCQW 3CCSW 3DLLW 3G71W 1S72W 3PIPW 1VQKW 4U67W 5GAEa 4IO9W 4C1NA 1N8RX 1YJ9W 5DM7W 1VQPW 3CF5W 1VQ6W 2QEXW 1K73X 4WFAW 1YJNW 1VQ4W 2ZJQW 4UY8Z 3CMAW 1VQ9W 3CCEW 1YIJW 1VQNW 1YITW 3CC2W 2QA4W 1KC8X 1NJIX 1YHQW 5JVGW 5HL7W 3CCVW 1Q81X 3CC4W 3CCUW 1Q7YX 1W2BV 3J7ZZ 1KD1X 3CCRW 3G4SW 3CXCV 3CCJW 3OW2V 1JJ2V 1QVGV 1VQMW 1Q86X 3I55W 3CCLW 1BXYA 3CPWV 4WFBW 1YI2W 3G6EW 1VQOW 4WFNW 1QVFV 4IOCW 1VQ7W 2ZJRW 5GAHa 2ZJPW 1VQ8W
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GAD a;  1K8A X;  4IOA W;  5GAG a;  1VQ5 W;  2OTL W;  5JVH W;  4WF9 W;  3CD6 W;  5DM6 W;  3CC7 W;  1M1K X;  4WCE W;  1YJW W;  1K9M X;  1M90 X;  2OTJ W;  3CCM W;  1KQS V;  3CME W;  1Q82 X;  3PIO W;  1VQL W;  3I56 W;  3CCQ W;  3CCS W;  3DLL W;  3G71 W;  1S72 W;  3PIP W;  1VQK W;  4U67 W;  5GAE a;  4IO9 W;  1N8R X;  1YJ9 W;  5DM7 W;  1VQP W;  3CF5 W;  1VQ6 W;  2QEX W;  1K73 X;  4WFA W;  1YJN W;  1VQ4 W;  2ZJQ W;  4UY8 Z;  3CMA W;  1VQ9 W;  3CCE W;  1YIJ W;  1VQN W;  1YIT W;  3CC2 W;  2QA4 W;  1KC8 X;  1NJI X;  1YHQ W;  5JVG W;  5HL7 W;  3CCV W;  1Q81 X;  3CC4 W;  3CCU W;  1Q7Y X;  1W2B V;  3J7Z Z;  1KD1 X;  3CCR W;  3G4S W;  3CXC V;  3CCJ W;  3OW2 V;  1JJ2 V;  1QVG V;  1VQM W;  1Q86 X;  3I55 W;  3CCL W;  1BXY A;  3CPW V;  4WFB W;  1YI2 W;  3G6E W;  1VQO W;  4WFN W;  1QVF V;  4IOC W;  1VQ7 W;  2ZJR W;  5GAH a;  2ZJP W;  1VQ8 W; 
#chains in the Genus database with same CATH topology
 5GAD a;  1K8A X;  4IOA W;  3O2H A;  5GAG a;  1VQ5 W;  1MG9 A;  4YJX A;  2OTL W;  4DKI A;  5JVH W;  4CPK A;  4WF9 W;  3W7U A;  3CD6 W;  1RQV A;  5DM6 W;  3CC7 W;  3GW1 A;  3W7T A;  1M1K X;  4WCE W;  1YJW W;  1K9M X;  1M90 X;  2OTJ W;  3ZFZ A;  1MBU C;  3CCM W;  1KQS V;  3CME W;  1Q82 X;  5GW7 A;  3PIO W;  3W7W A;  1VQL W;  3I56 W;  3CCQ W;  3CCS W;  1R6Q C;  3DLL W;  2W9R A;  3G71 W;  1S72 W;  5M18 A;  3PIP W;  1VQK W;  4U67 W;  5GAE a;  4IO9 W;  1MWR A;  4C1N A;  1N8R X;  1YJ9 W;  5DM7 W;  1MBX C;  1VQP W;  3CF5 W;  1VQ6 W;  3O2O A;  2QEX W;  1K73 X;  3G19 A;  4WFA W;  1YJN W;  1VQ4 W;  2ZJQ W;  4UY8 Z;  3CMA W;  3GQ1 A;  1VQ9 W;  3CCE W;  1YIJ W;  1VQN W;  1RQU A;  3O1F B;  4CJN A;  1YIT W;  3CC2 W;  2QA4 W;  1KC8 X;  1NJI X;  1YHQ W;  1LZW A;  3O2B A;  5JVG W;  5HL7 W;  3G3P A;  3CCV W;  3D3I A;  3GQ0 A;  2WA8 A;  1MBV B;  1Q81 X;  1MWS A;  3CC4 W;  3CCU W;  3W7X A;  1Q7Y X;  1W2B V;  3J7Z Z;  1KD1 X;  3CCR W;  4YJM A;  1MWT A;  3G4S W;  3CXC V;  3CCJ W;  3OW2 V;  1JJ2 V;  3ZG5 A;  1QVG V;  1VQM W;  5M1A A;  5M19 A;  1Q86 X;  3I55 W;  3CCL W;  1DD4 A;  3ZG0 A;  1BXY A;  3CPW V;  4BL3 A;  4WFB W;  1YI2 W;  3G6E W;  1VQO W;  5CA3 A;  4WFN W;  3W7S A;  1R6O C;  4YKA A;  1QVF V;  4IOC W;  1VQ7 W;  2ZJR W;  5GAH a;  1VQQ A;  1DD3 A;  3O1F A;  2ZJP W;  1CTF A;  4BL2 A;  1RQS A;  1VQ8 W;  3G1B A;  2WA9 A;  3DNJ A;  1MWU A; 
#chains in the Genus database with same CATH homology
 5GAD a;  1K8A X;  4IOA W;  5GAG a;  1VQ5 W;  2OTL W;  5JVH W;  4WF9 W;  3CD6 W;  5DM6 W;  3CC7 W;  1M1K X;  4WCE W;  1YJW W;  1K9M X;  1M90 X;  2OTJ W;  3CCM W;  1KQS V;  3CME W;  1Q82 X;  3PIO W;  1VQL W;  3I56 W;  3CCQ W;  3CCS W;  3DLL W;  3G71 W;  1S72 W;  3PIP W;  1VQK W;  4U67 W;  5GAE a;  4IO9 W;  4C1N A;  1N8R X;  1YJ9 W;  5DM7 W;  1VQP W;  3CF5 W;  1VQ6 W;  2QEX W;  1K73 X;  4WFA W;  1YJN W;  1VQ4 W;  2ZJQ W;  4UY8 Z;  3CMA W;  1VQ9 W;  3CCE W;  1YIJ W;  1VQN W;  1YIT W;  3CC2 W;  2QA4 W;  1KC8 X;  1NJI X;  1YHQ W;  5JVG W;  5HL7 W;  3CCV W;  1Q81 X;  3CC4 W;  3CCU W;  1Q7Y X;  1W2B V;  3J7Z Z;  1KD1 X;  3CCR W;  3G4S W;  3CXC V;  3CCJ W;  3OW2 V;  1JJ2 V;  1QVG V;  1VQM W;  1Q86 X;  3I55 W;  3CCL W;  1BXY A;  3CPW V;  4WFB W;  1YI2 W;  3G6E W;  1VQO W;  4WFN W;  1QVF V;  4IOC W;  1VQ7 W;  2ZJR W;  5GAH a;  2ZJP W;  1VQ8 W; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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