1KDUA

Sequential 1h nmr assignments and secondary structure of the kringle domain from urokinase
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
85
structure length
85
Chain Sequence
TCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRRRPWCYVQVGLKPLVQECMVHDCAD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Plasminogen activation
molecule keywords PLASMINOGEN ACTIVATOR
publication title Solution structure of the kringle domain from urokinase-type plasminogen activator.
pubmed doi rcsb
source organism Homo sapiens
total genus 5
structure length 85
sequence length 85
ec nomenclature ec 3.4.21.73: U-plasminogen activator.
pdb deposition date 1993-07-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00051 Kringle Kringle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.20.10 Mainly Beta Beta Barrel Plasminogen Kringle 4 Plasminogen Kringle 4 1kduA00
4O03A 5CT3A 1BHTA 2FD6A 3U73A 1GP9A 4BVWA 2QJ4A 2I9BA 1I71A 1PKRA 1GMNA 2KJ4A 2K4RA 1HPKA 3BT2A 1URKA 2K51A 3BT1A 2PF1A 4CIKA 4BV5A 5COEA 5CP9A 2L0SA 5CT1A 2SPTA 2PK4A 2I9AA 3SP8A 1CEAA 1KRNA 3KIVA 4KIVA 3MKPA 1NL1A 1JFNA 5CS1A 1PK4A 1GMOA 4A5TS 1PMLA 5CS3A 4BVVA 1CEBA 1B2IA 4IUAA 1A0HA 3K65A 2FEBA 4HZHA 4BV7A 1KDUA 2KNFA 5HPGA 3NXPA 2DOIA 2QJ2A 1HPJA 5CSQA 2HPPP 4BVDA 5CS9A 2HPQP 5CT2A 2PF2A 1KIVA 4BVCA 3E6PL 4NZQA 3HN4A 4D3CA 1I5KA 3LAQA 4DURA 5CS5A 1KI0A 1NK1A 1PK2A 2DOHX 1TPKA 1PMKA 1NL2A
chains in the Genus database with same CATH superfamily
4O03A 5CT3A 1BHTA 2FD6A 3U73A 1GP9A 4BVWA 2QJ4A 2I9BA 1I71A 1PKRA 1GMNA 2KJ4A 2K4RA 1HPKA 3BT2A 1URKA 2K51A 3BT1A 2PF1A 4CIKA 4BV5A 5COEA 5CP9A 2L0SA 5CT1A 2SPTA 2PK4A 2I9AA 3SP8A 1CEAA 1KRNA 3KIVA 4KIVA 3MKPA 1NL1A 1JFNA 5CS1A 1PK4A 1GMOA 4A5TS 1PMLA 5CS3A 4BVVA 1CEBA 1B2IA 4IUAA 1A0HA 3K65A 2FEBA 4HZHA 4BV7A 1KDUA 2KNFA 5HPGA 3NXPA 2DOIA 2QJ2A 1HPJA 5CSQA 2HPPP 4BVDA 5CS9A 2HPQP 5CT2A 2PF2A 1KIVA 4BVCA 3E6PL 4NZQA 3HN4A 4D3CA 1I5KA 3LAQA 4DURA 5CS5A 1KI0A 1NK1A 1PK2A 2DOHX 1TPKA 1PMKA 1NL2A
chains in the Genus database with same CATH topology
4O03A 5CT3A 1BHTA 2FD6A 3U73A 1GP9A 4BVWA 2QJ4A 2I9BA 1I71A 1PKRA 1GMNA 2KJ4A 2K4RA 1HPKA 3BT2A 1URKA 2K51A 3BT1A 2PF1A 4CIKA 4BV5A 5COEA 5CP9A 2L0SA 5CT1A 2SPTA 2PK4A 2I9AA 3SP8A 1CEAA 1KRNA 3KIVA 4KIVA 3MKPA 1NL1A 1JFNA 5CS1A 1PK4A 1GMOA 4A5TS 1PMLA 5CS3A 4BVVA 1CEBA 1B2IA 4IUAA 1A0HA 3K65A 2FEBA 4HZHA 4BV7A 1KDUA 2KNFA 5HPGA 3NXPA 2DOIA 2QJ2A 1HPJA 5CSQA 2HPPP 4BVDA 5CS9A 2HPQP 5CT2A 2PF2A 1KIVA 4BVCA 3E6PL 4NZQA 3HN4A 4D3CA 1I5KA 3LAQA 4DURA 5CS5A 1KI0A 1NK1A 1PK2A 2DOHX 1TPKA 1PMKA 1NL2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4O03 A;  5CT3 A;  1BHT A;  2FD6 A;  3U73 A;  1GP9 A;  4BVW A;  2QJ4 A;  2I9B A;  1I71 A;  1PKR A;  1GMN A;  2KJ4 A;  2K4R A;  1HPK A;  3BT2 A;  1URK A;  2K51 A;  3BT1 A;  2PF1 A;  4CIK A;  4BV5 A;  5COE A;  5CP9 A;  2L0S A;  5CT1 A;  2SPT A;  2PK4 A;  2I9A A;  3SP8 A;  1CEA A;  1KRN A;  3KIV A;  4KIV A;  3MKP A;  1NL1 A;  1JFN A;  5CS1 A;  1PK4 A;  1GMO A;  4A5T S;  1PML A;  5CS3 A;  4BVV A;  1CEB A;  1B2I A;  4IUA A;  1A0H A;  3K65 A;  2FEB A;  4HZH A;  4BV7 A;  1KDU A;  2KNF A;  5HPG A;  3NXP A;  2DOI A;  2QJ2 A;  1HPJ A;  5CSQ A;  2HPP P;  4BVD A;  5CS9 A;  2HPQ P;  5CT2 A;  2PF2 A;  1KIV A;  4BVC A;  3E6P L;  4NZQ A;  3HN4 A;  4D3C A;  1I5K A;  3LAQ A;  4DUR A;  5CS5 A;  1KI0 A;  1NK1 A;  1PK2 A;  2DOH X;  1TPK A;  1PMK A;  1NL2 A; 
#chains in the Genus database with same CATH topology
 4O03 A;  5CT3 A;  1BHT A;  2FD6 A;  3U73 A;  1GP9 A;  4BVW A;  2QJ4 A;  2I9B A;  1I71 A;  1PKR A;  1GMN A;  2KJ4 A;  2K4R A;  1HPK A;  3BT2 A;  1URK A;  2K51 A;  3BT1 A;  2PF1 A;  4CIK A;  4BV5 A;  5COE A;  5CP9 A;  2L0S A;  5CT1 A;  2SPT A;  2PK4 A;  2I9A A;  3SP8 A;  1CEA A;  1KRN A;  3KIV A;  4KIV A;  3MKP A;  1NL1 A;  1JFN A;  5CS1 A;  1PK4 A;  1GMO A;  4A5T S;  1PML A;  5CS3 A;  4BVV A;  1CEB A;  1B2I A;  4IUA A;  1A0H A;  3K65 A;  2FEB A;  4HZH A;  4BV7 A;  1KDU A;  2KNF A;  5HPG A;  3NXP A;  2DOI A;  2QJ2 A;  1HPJ A;  5CSQ A;  2HPP P;  4BVD A;  5CS9 A;  2HPQ P;  5CT2 A;  2PF2 A;  1KIV A;  4BVC A;  3E6P L;  4NZQ A;  3HN4 A;  4D3C A;  1I5K A;  3LAQ A;  4DUR A;  5CS5 A;  1KI0 A;  1NK1 A;  1PK2 A;  2DOH X;  1TPK A;  1PMK A;  1NL2 A; 
#chains in the Genus database with same CATH homology
 4O03 A;  5CT3 A;  1BHT A;  2FD6 A;  3U73 A;  1GP9 A;  4BVW A;  2QJ4 A;  2I9B A;  1I71 A;  1PKR A;  1GMN A;  2KJ4 A;  2K4R A;  1HPK A;  3BT2 A;  1URK A;  2K51 A;  3BT1 A;  2PF1 A;  4CIK A;  4BV5 A;  5COE A;  5CP9 A;  2L0S A;  5CT1 A;  2SPT A;  2PK4 A;  2I9A A;  3SP8 A;  1CEA A;  1KRN A;  3KIV A;  4KIV A;  3MKP A;  1NL1 A;  1JFN A;  5CS1 A;  1PK4 A;  1GMO A;  4A5T S;  1PML A;  5CS3 A;  4BVV A;  1CEB A;  1B2I A;  4IUA A;  1A0H A;  3K65 A;  2FEB A;  4HZH A;  4BV7 A;  1KDU A;  2KNF A;  5HPG A;  3NXP A;  2DOI A;  2QJ2 A;  1HPJ A;  5CSQ A;  2HPP P;  4BVD A;  5CS9 A;  2HPQ P;  5CT2 A;  2PF2 A;  1KIV A;  4BVC A;  3E6P L;  4NZQ A;  3HN4 A;  4D3C A;  1I5K A;  3LAQ A;  4DUR A;  5CS5 A;  1KI0 A;  1NK1 A;  1PK2 A;  2DOH X;  1TPK A;  1PMK A;  1NL2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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