2C1JA

Molecular basis for the recognition of phosphorylated and phosphoacetylated histone h3 by 14-3-3
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
230
structure length
230
Chain Sequence
MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular Basis for the Recognition of Phosphorylated and Phosphoacetylated Histone H3 by 14-3-3.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords 14-3-3 PROTEIN ZETA/DELTA
total genus 99
structure length 230
sequence length 230
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-09-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 2c1jA00
3M51A 1QJBA 3SP5A 4Y5IA 4E2EA 3P1OA 4Y32A 4ZDRA 4N7GA 2BTPA 2O8PA 3SMKA 5BTVA 5BY9A 5LHOA 3EFZA 4DX0A 5LX2A 3RDHA 4DNKA 3UZDA 4FL5A 3UBWA 3P1PA 3P1NA 5EWZA 1O9FA 4JC3A 1A4OA 3AXYC 4DHNA 2BQ0A 3P1QA 2C23A 4O46A 3IQVA 4Y3BA 3U9XA 2O02A 2V7DA 3SPRA 4N7YA 4DHOA 2C1JA 3SMMA 1O9CA 5LU1A 3MHRA 3O8IA 2WH0A 3IQJA 4DHSA 3SMOA 4JDDA 4BG6A 1A37A 3IQUA 5IQPA 4QLIA 4F7RA 3T0MA 5F74A 4IEAA 4DAUA 5LVZA 4IHLA 5J31A 1QJAA 3SMNA 4DHPA 1O9EA 4HKCA 5D3EA 4DHMA 5EXAA 4FR3A 3SMLA 4J6SA 1O9DA 1YWTA 5LU2A 3E6YA 1A38A 4N84A 4DHQA 4FJ3A 4DHUA 5D2DA 3UX0A 3P1SA 2BR9A 4DHRA 4ZQ0A 2C63A 3UALA 3M50A 2C1NA 5D3FA 3T0LA 4GNTA 4DHTA 2O98A 2B05A 1YZ5A 1IB1A 3CU8A 3NKXA 2C74A 2NPMA 5HF3A 3LW1A 4WRQA 3P1RA 4DATA
chains in the Genus database with same CATH superfamily
3M51A 1QJBA 3SP5A 4Y5IA 4E2EA 3P1OA 4Y32A 4ZDRA 3X0UA 4N7GA 2BTPA 2O8PA 4QX3A 3SMKA 5BTVA 5BY9A 5LHOA 3EFZA 4DX0A 5LX2A 3RDHA 4DNKA 3UZDA 4FL5A 3UBWA 3P1PA 3P1NA 5EWZA 1O9FA 4JC3A 3I4RA 1A4OA 3AXYC 3ZHEB 4W8JA 4DHNA 2BQ0A 3P1QA 2C23A 4O46A 3IQVA 4Y3BA 3U9XA 1W99A 4ARYA 3CQGA 2O02A 2V7DA 3SPRA 4N7YA 4DHOA 2C1JA 3SMMA 1CIYA 1O9CA 1DLCA 5LU1A 3MHRA 3O8IA 2WH0A 3IQJA 4DHSA 3SMOA 4QX1A 4JDDA 4BG6A 1A37A 3IQUA 5IQPA 4QLIA 4F7RA 3T0MA 5F74A 4IEAA 4DAUA 1S2XA 3EB7A 5LVZA 4IHLA 5J31A 1QJAA 3SMNA 4DHPA 1O9EA 4HKCA 5D3EA 4DHMA 5EXAA 4FR3A 4QX0A 4J6SA 3SMLA 1O9DA 1YWTA 1JI6A 1URJA 5LU2A 4ARXA 3E6YA 1A38A 4N84A 4DHQA 4FJ3A 4DHUA 5D2DA 3UX0A 3P1SA 1I5PA 2BR9A 4MOAA 4DHRA 4ZQ0A 2C63A 3UALA 3M50A 2C1NA 5D3FA 3T0LA 2C9KA 4GNTA 4DHTA 2O98A 2B05A 1YZ5A 4D8MA 1IB1A 3CU8A 3NKXA 4QX2A 2C74A 2NPMA 5HF3A 3CQCA 3LW1A 4WRQA 3P1RA 4DATA
chains in the Genus database with same CATH topology
3M51A 1QJBA 3SP5A 4Y5IA 4E2EA 3P1OA 4Y32A 4ZDRA 4N7GA 2BTPA 2O8PA 3SMKA 5BTVA 5BY9A 5LHOA 3EFZA 4DX0A 5LX2A 3RDHA 4DNKA 3UZDA 4FL5A 3UBWA 3P1PA 3P1NA 5EWZA 1O9FA 4JC3A 1A4OA 3AXYC 4DHNA 2BQ0A 3P1QA 2C23A 4O46A 3IQVA 4Y3BA 3U9XA 2O02A 2V7DA 3SPRA 4N7YA 4DHOA 2C1JA 3SMMA 1O9CA 5LU1A 3MHRA 3O8IA 2WH0A 3IQJA 4DHSA 3SMOA 4JDDA 4BG6A 1A37A 3IQUA 5IQPA 4QLIA 4F7RA 3T0MA 5F74A 4IEAA 4DAUA 5LVZA 4IHLA 5J31A 1QJAA 3SMNA 4DHPA 1O9EA 4HKCA 5D3EA 4DHMA 5EXAA 4FR3A 3SMLA 4J6SA 1O9DA 1YWTA 5LU2A 3E6YA 1A38A 4N84A 4DHQA 4FJ3A 4DHUA 5D2DA 3UX0A 3P1SA 2BR9A 4DHRA 4ZQ0A 2C63A 3UALA 3M50A 2C1NA 5D3FA 3T0LA 4GNTA 4DHTA 2O98A 2B05A 1YZ5A 1IB1A 3CU8A 3NKXA 2C74A 2NPMA 5HF3A 3LW1A 4WRQA 3P1RA 4DATA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3M51 A;  1QJB A;  3SP5 A;  4Y5I A;  4E2E A;  3P1O A;  4Y32 A;  4ZDR A;  4N7G A;  2BTP A;  2O8P A;  3SMK A;  5BTV A;  5BY9 A;  5LHO A;  3EFZ A;  4DX0 A;  5LX2 A;  3RDH A;  4DNK A;  3UZD A;  4FL5 A;  3UBW A;  3P1P A;  3P1N A;  5EWZ A;  1O9F A;  4JC3 A;  1A4O A;  3AXY C;  4DHN A;  2BQ0 A;  3P1Q A;  2C23 A;  4O46 A;  3IQV A;  4Y3B A;  3U9X A;  2O02 A;  2V7D A;  3SPR A;  4N7Y A;  4DHO A;  2C1J A;  3SMM A;  1O9C A;  5LU1 A;  3MHR A;  3O8I A;  2WH0 A;  3IQJ A;  4DHS A;  3SMO A;  4JDD A;  4BG6 A;  1A37 A;  3IQU A;  5IQP A;  4QLI A;  4F7R A;  3T0M A;  5F74 A;  4IEA A;  4DAU A;  5LVZ A;  4IHL A;  5J31 A;  1QJA A;  3SMN A;  4DHP A;  1O9E A;  4HKC A;  5D3E A;  4DHM A;  5EXA A;  4FR3 A;  3SML A;  4J6S A;  1O9D A;  1YWT A;  5LU2 A;  3E6Y A;  1A38 A;  4N84 A;  4DHQ A;  4FJ3 A;  4DHU A;  5D2D A;  3UX0 A;  3P1S A;  2BR9 A;  4DHR A;  4ZQ0 A;  2C63 A;  3UAL A;  3M50 A;  2C1N A;  5D3F A;  3T0L A;  4GNT A;  4DHT A;  2O98 A;  2B05 A;  1YZ5 A;  1IB1 A;  3CU8 A;  3NKX A;  2C74 A;  2NPM A;  5HF3 A;  3LW1 A;  4WRQ A;  3P1R A;  4DAT A; 
#chains in the Genus database with same CATH topology
 3M51 A;  1QJB A;  3SP5 A;  4Y5I A;  4E2E A;  3P1O A;  4Y32 A;  4ZDR A;  3X0U A;  4N7G A;  2BTP A;  2O8P A;  4QX3 A;  3SMK A;  5BTV A;  5BY9 A;  5LHO A;  3EFZ A;  4DX0 A;  5LX2 A;  3RDH A;  4DNK A;  3UZD A;  4FL5 A;  3UBW A;  3P1P A;  3P1N A;  5EWZ A;  1O9F A;  4JC3 A;  3I4R A;  1A4O A;  3AXY C;  3ZHE B;  4W8J A;  4DHN A;  2BQ0 A;  3P1Q A;  2C23 A;  4O46 A;  3IQV A;  4Y3B A;  3U9X A;  1W99 A;  4ARY A;  3CQG A;  2O02 A;  2V7D A;  3SPR A;  4N7Y A;  4DHO A;  2C1J A;  3SMM A;  1CIY A;  1O9C A;  1DLC A;  5LU1 A;  3MHR A;  3O8I A;  2WH0 A;  3IQJ A;  4DHS A;  3SMO A;  4QX1 A;  4JDD A;  4BG6 A;  1A37 A;  3IQU A;  5IQP A;  4QLI A;  4F7R A;  3T0M A;  5F74 A;  4IEA A;  4DAU A;  1S2X A;  3EB7 A;  5LVZ A;  4IHL A;  5J31 A;  1QJA A;  3SMN A;  4DHP A;  1O9E A;  4HKC A;  5D3E A;  4DHM A;  5EXA A;  4FR3 A;  4QX0 A;  4J6S A;  3SML A;  1O9D A;  1YWT A;  1JI6 A;  1URJ A;  5LU2 A;  4ARX A;  3E6Y A;  1A38 A;  4N84 A;  4DHQ A;  4FJ3 A;  4DHU A;  5D2D A;  3UX0 A;  3P1S A;  1I5P A;  2BR9 A;  4MOA A;  4DHR A;  4ZQ0 A;  2C63 A;  3UAL A;  3M50 A;  2C1N A;  5D3F A;  3T0L A;  2C9K A;  4GNT A;  4DHT A;  2O98 A;  2B05 A;  1YZ5 A;  4D8M A;  1IB1 A;  3CU8 A;  3NKX A;  4QX2 A;  2C74 A;  2NPM A;  5HF3 A;  3CQC A;  3LW1 A;  4WRQ A;  3P1R A;  4DAT A; 
#chains in the Genus database with same CATH homology
 3M51 A;  1QJB A;  3SP5 A;  4Y5I A;  4E2E A;  3P1O A;  4Y32 A;  4ZDR A;  4N7G A;  2BTP A;  2O8P A;  3SMK A;  5BTV A;  5BY9 A;  5LHO A;  3EFZ A;  4DX0 A;  5LX2 A;  3RDH A;  4DNK A;  3UZD A;  4FL5 A;  3UBW A;  3P1P A;  3P1N A;  5EWZ A;  1O9F A;  4JC3 A;  1A4O A;  3AXY C;  4DHN A;  2BQ0 A;  3P1Q A;  2C23 A;  4O46 A;  3IQV A;  4Y3B A;  3U9X A;  2O02 A;  2V7D A;  3SPR A;  4N7Y A;  4DHO A;  2C1J A;  3SMM A;  1O9C A;  5LU1 A;  3MHR A;  3O8I A;  2WH0 A;  3IQJ A;  4DHS A;  3SMO A;  4JDD A;  4BG6 A;  1A37 A;  3IQU A;  5IQP A;  4QLI A;  4F7R A;  3T0M A;  5F74 A;  4IEA A;  4DAU A;  5LVZ A;  4IHL A;  5J31 A;  1QJA A;  3SMN A;  4DHP A;  1O9E A;  4HKC A;  5D3E A;  4DHM A;  5EXA A;  4FR3 A;  3SML A;  4J6S A;  1O9D A;  1YWT A;  5LU2 A;  3E6Y A;  1A38 A;  4N84 A;  4DHQ A;  4FJ3 A;  4DHU A;  5D2D A;  3UX0 A;  3P1S A;  2BR9 A;  4DHR A;  4ZQ0 A;  2C63 A;  3UAL A;  3M50 A;  2C1N A;  5D3F A;  3T0L A;  4GNT A;  4DHT A;  2O98 A;  2B05 A;  1YZ5 A;  1IB1 A;  3CU8 A;  3NKX A;  2C74 A;  2NPM A;  5HF3 A;  3LW1 A;  4WRQ A;  3P1R A;  4DAT A; 
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similar chains in the Genus database (?% sequence similarity)
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