2NPM | Genus

Total Genus 105

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	105
sequence length	239
structure length	237
Chain Sequence	MSDSVNARESNVYMAKLAEQAERYDEMAKYMKDVVEARQEELTVEERNLLSVAYKNAVGSRRSSWRIISSVEQKEHSRNAEDASKMCGKYRSKVEAELTDICNDILTMLDKHLIPTATSPDSKVFYFKMKGDYHRYISEFSTGDSKQSSAEDALKAYKDATVVAKDLEPTHPIRLGLALNFSVFHYEILNEPRAAIDMAKEAFEMAIEQLDKLSEDCYKDSTLIMQLLRDNLTLWTA

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Protein binding
source organism	Cryptosporidium parvum
publication title	Characterization of 14-3-3 proteins from Cryptosporidium parvum. pubmed doi rcsb
molecule keywords	14-3-3 domain containing protein
total genus	105
structure length	237
sequence length	239
chains with identical sequence	B
ec nomenclature
pdb deposition date	2006-10-27

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00244	14-3-3	14-3-3 protein

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.190.20	Mainly Alpha	Up-down Bundle	Delta-Endotoxin; domain 1	14-3-3 domain	2npmA00

4DHUA 4DNKA 2V7DA 5LX2A 3O8IA 1YWTA 2O8PA 2BTPA 4DHTA 4E2EA 2O02A 2O98A 2WH0A 5EWZA 2C1JA 3CU8A 1QJAA 4DHRA 4DHQA 1YZ5A 5LU1A 5LHOA 3SP5A 2C74A 3P1SA 4ZDRA 3IQVA 5BTVA 3LW1A 1A4OA 3U9XA 5D3EA 3IQUA 4Y5IA 4ZQ0A 4HKCA 5J31A 3P1OA 4JDDA 3T0MA 5D3FA 3M50A 3P1NA 3E6YA 4BG6A 4DATA 2NPMA 5BY9A 1O9CA 5F74A 3UX0A 3P1PA 1O9DA 4N84A 4JC3A 3SMNA 3MHRA 4N7GA 3EFZA 1QJBA 4DHOA 2C23A 1A37A 4DHSA 5LU2A 3T0LA 3NKXA 4FJ3A 4WRQA 2BR9A 3AXYC 2C63A 4DHMA 3SMMA 3UBWA 4FR3A 3SMKA 3IQJA 4DHNA 3SMOA 5EXAA 4DAUA 4IHLA 1O9EA 1IB1A 1A38A 3M51A 5D2DA 4Y32A 4IEAA 2BQ0A 4J6SA 4O46A 4F7RA 3SPRA 4GNTA 4DX0A 1O9FA 5LVZA 3P1RA 4Y3BA 4QLIA 3UALA 5IQPA 3UZDA 4FL5A 4DHPA 2C1NA 3SMLA 4N7YA 5HF3A 3P1QA 3RDHA 2B05A
chains in the Genus database with same CATH superfamily

4DHUA 1S2XA 3CQCA 4D8MA 4W8JA 4DNKA 4MOAA 2V7DA 3EB7A 5LX2A 1JI6A 3O8IA 4QX3A 1YWTA 1W99A 2O8PA 2BTPA 4DHTA 4E2EA 2O02A 2O98A 2WH0A 5EWZA 2C1JA 3CU8A 1QJAA 4DHRA 4DHQA 1YZ5A 5LU1A 2C9KA 5LHOA 3SP5A 3CQGA 2C74A 3P1SA 4ZDRA 3IQVA 5BTVA 3LW1A 1A4OA 3U9XA 5D3EA 3IQUA 4Y5IA 4ZQ0A 4HKCA 5J31A 3P1OA 4JDDA 3T0MA 5D3FA 3M50A 3P1NA 3E6YA 4BG6A 3ZHEB 4DATA 1DLCA 2NPMA 5BY9A 1O9CA 5F74A 3UX0A 3P1PA 1I5PA 1O9DA 4N84A 4JC3A 1URJA 3SMNA 3MHRA 4N7GA 3EFZA 1QJBA 4DHOA 2C23A 1A37A 4DHSA 3RDHA 5LU2A 3T0LA 3NKXA 4FJ3A 4QX0A 4WRQA 2BR9A 3AXYC 2C63A 4DHMA 3X0UA 4QX1A 3SMMA 3UBWA 4FR3A 3SMKA 3IQJA 4DHNA 3SMOA 5EXAA 4DAUA 4IHLA 4QX2A 1O9EA 1IB1A 1A38A 3M51A 5D2DA 4ARXA 4Y32A 2BQ0A 4J6SA 4O46A 4F7RA 3SPRA 4GNTA 4DX0A 1O9FA 5LVZA 3P1RA 4ARYA 4Y3BA 4QLIA 3UALA 5IQPA 3UZDA 4FL5A 4DHPA 1CIYA 2C1NA 3SMLA 4N7YA 3I4RA 5HF3A 3P1QA 4IEAA 2B05A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4DHU A;  4DNK A;  2V7D A;  5LX2 A;  3O8I A;  1YWT A;  2O8P A;  2BTP A;  4DHT A;  4E2E A;  2O02 A;  2O98 A;  2WH0 A;  5EWZ A;  2C1J A;  3CU8 A;  1QJA A;  4DHR A;  4DHQ A;  1YZ5 A;  5LU1 A;  5LHO A;  3SP5 A;  2C74 A;  3P1S A;  4ZDR A;  3IQV A;  5BTV A;  3LW1 A;  1A4O A;  3U9X A;  5D3E A;  3IQU A;  4Y5I A;  4ZQ0 A;  4HKC A;  5J31 A;  3P1O A;  4JDD A;  3T0M A;  5D3F A;  3M50 A;  3P1N A;  3E6Y A;  4BG6 A;  4DAT A;  2NPM A;  5BY9 A;  1O9C A;  5F74 A;  3UX0 A;  3P1P A;  1O9D A;  4N84 A;  4JC3 A;  3SMN A;  3MHR A;  4N7G A;  3EFZ A;  1QJB A;  4DHO A;  2C23 A;  1A37 A;  4DHS A;  5LU2 A;  3T0L A;  3NKX A;  4FJ3 A;  4WRQ A;  2BR9 A;  3AXY C;  2C63 A;  4DHM A;  3SMM A;  3UBW A;  4FR3 A;  3SMK A;  3IQJ A;  4DHN A;  3SMO A;  5EXA A;  4DAU A;  4IHL A;  1O9E A;  1IB1 A;  1A38 A;  3M51 A;  5D2D A;  4Y32 A;  4IEA A;  2BQ0 A;  4J6S A;  4O46 A;  4F7R A;  3SPR A;  4GNT A;  4DX0 A;  1O9F A;  5LVZ A;  3P1R A;  4Y3B A;  4QLI A;  3UAL A;  5IQP A;  3UZD A;  4FL5 A;  4DHP A;  2C1N A;  3SML A;  4N7Y A;  5HF3 A;  3P1Q A;  3RDH A;  2B05 A; 
#chains in the Genus database with same CATH topology
 4DHU A;  1S2X A;  3CQC A;  4D8M A;  4W8J A;  4DNK A;  4MOA A;  2V7D A;  3EB7 A;  5LX2 A;  1JI6 A;  3O8I A;  4QX3 A;  1YWT A;  1W99 A;  2O8P A;  2BTP A;  4DHT A;  4E2E A;  2O02 A;  2O98 A;  2WH0 A;  5EWZ A;  2C1J A;  3CU8 A;  1QJA A;  4DHR A;  4DHQ A;  1YZ5 A;  5LU1 A;  2C9K A;  5LHO A;  3SP5 A;  3CQG A;  2C74 A;  3P1S A;  4ZDR A;  3IQV A;  5BTV A;  3LW1 A;  1A4O A;  3U9X A;  5D3E A;  3IQU A;  4Y5I A;  4ZQ0 A;  4HKC A;  5J31 A;  3P1O A;  4JDD A;  3T0M A;  5D3F A;  3M50 A;  3P1N A;  3E6Y A;  4BG6 A;  3ZHE B;  4DAT A;  1DLC A;  2NPM A;  5BY9 A;  1O9C A;  5F74 A;  3UX0 A;  3P1P A;  1I5P A;  1O9D A;  4N84 A;  4JC3 A;  1URJ A;  3SMN A;  3MHR A;  4N7G A;  3EFZ A;  1QJB A;  4DHO A;  2C23 A;  1A37 A;  4DHS A;  3RDH A;  5LU2 A;  3T0L A;  3NKX A;  4FJ3 A;  4QX0 A;  4WRQ A;  2BR9 A;  3AXY C;  2C63 A;  4DHM A;  3X0U A;  4QX1 A;  3SMM A;  3UBW A;  4FR3 A;  3SMK A;  3IQJ A;  4DHN A;  3SMO A;  5EXA A;  4DAU A;  4IHL A;  4QX2 A;  1O9E A;  1IB1 A;  1A38 A;  3M51 A;  5D2D A;  4ARX A;  4Y32 A;  2BQ0 A;  4J6S A;  4O46 A;  4F7R A;  3SPR A;  4GNT A;  4DX0 A;  1O9F A;  5LVZ A;  3P1R A;  4ARY A;  4Y3B A;  4QLI A;  3UAL A;  5IQP A;  3UZD A;  4FL5 A;  4DHP A;  1CIY A;  2C1N A;  3SML A;  4N7Y A;  3I4R A;  5HF3 A;  3P1Q A;  4IEA A;  2B05 A; 
#chains in the Genus database with same CATH homology
 4DHU A;  4DNK A;  2V7D A;  5LX2 A;  3O8I A;  1YWT A;  2O8P A;  2BTP A;  4DHT A;  4E2E A;  2O02 A;  2O98 A;  2WH0 A;  5EWZ A;  2C1J A;  3CU8 A;  1QJA A;  4DHR A;  4DHQ A;  1YZ5 A;  5LU1 A;  5LHO A;  3SP5 A;  2C74 A;  3P1S A;  4ZDR A;  3IQV A;  5BTV A;  3LW1 A;  1A4O A;  3U9X A;  5D3E A;  3IQU A;  4Y5I A;  4ZQ0 A;  4HKC A;  5J31 A;  3P1O A;  4JDD A;  3T0M A;  5D3F A;  3M50 A;  3P1N A;  3E6Y A;  4BG6 A;  4DAT A;  2NPM A;  5BY9 A;  1O9C A;  5F74 A;  3UX0 A;  3P1P A;  1O9D A;  4N84 A;  4JC3 A;  3SMN A;  3MHR A;  4N7G A;  3EFZ A;  1QJB A;  4DHO A;  2C23 A;  1A37 A;  4DHS A;  5LU2 A;  3T0L A;  3NKX A;  4FJ3 A;  4WRQ A;  2BR9 A;  3AXY C;  2C63 A;  4DHM A;  3SMM A;  3UBW A;  4FR3 A;  3SMK A;  3IQJ A;  4DHN A;  3SMO A;  5EXA A;  4DAU A;  4IHL A;  1O9E A;  1IB1 A;  1A38 A;  3M51 A;  5D2D A;  4Y32 A;  4IEA A;  2BQ0 A;  4J6S A;  4O46 A;  4F7R A;  3SPR A;  4GNT A;  4DX0 A;  1O9F A;  5LVZ A;  3P1R A;  4Y3B A;  4QLI A;  3UAL A;  5IQP A;  3UZD A;  4FL5 A;  4DHP A;  2C1N A;  3SML A;  4N7Y A;  5HF3 A;  3P1Q A;  3RDH A;  2B05 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2NPMA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations