2O02A

Phosphorylation independent interactions between 14-3-3 and exoenzyme s: from structure to pathogenesis
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
230
structure length
224
Chain Sequence
MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Phosphorylation-independent interaction between 14-3-3 and exoenzyme S: from structure to pathogenesis
pubmed doi rcsb
molecule tags Protein binding/toxin
source organism Homo sapiens
molecule keywords 14-3-3 protein zeta/delta
total genus 99
structure length 224
sequence length 230
chains with identical sequence B
ec nomenclature
pdb deposition date 2006-11-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 2o02A00
2WH0A 3SMNA 4N7GA 3P1PA 4HKCA 3T0LA 4DHPA 2NPMA 3O8IA 3SMOA 4FL5A 3SP5A 2BR9A 3M50A 3UBWA 3UX0A 4DNKA 5J31A 4JDDA 2V7DA 1YZ5A 5LHOA 2O02A 4O46A 5BTVA 5HF3A 2C63A 4Y3BA 4ZQ0A 1O9EA 1A4OA 5LX2A 3P1QA 3NKXA 3M51A 5F74A 4N84A 4GNTA 5BY9A 4DHMA 4N7YA 4WRQA 3IQJA 4DAUA 5LU2A 4DHNA 4J6SA 1YWTA 4DATA 5D2DA 1O9FA 4IEAA 2B05A 4FJ3A 3IQUA 4DHQA 3IQVA 3SPRA 2C23A 4QLIA 3CU8A 3T0MA 2C74A 1A37A 3SMKA 5LU1A 4DHOA 2C1NA 2C1JA 4BG6A 4ZDRA 3UALA 4IHLA 3RDHA 4F7RA 3U9XA 4FR3A 3LW1A 1QJBA 4DHSA 1A38A 1QJAA 5LVZA 2O8PA 3P1OA 4DHUA 3EFZA 3P1RA 1O9DA 3SMLA 2O98A 3P1NA 1IB1A 2BTPA 4DHRA 5IQPA 4Y32A 5D3FA 2BQ0A 3SMMA 4DHTA 1O9CA 5EWZA 4Y5IA 5D3EA 3MHRA 4DX0A 3AXYC 4E2EA 3P1SA 5EXAA 3E6YA 4JC3A 3UZDA
chains in the Genus database with same CATH superfamily
2WH0A 3SMNA 4N7GA 4QX2A 3P1PA 5EXAA 4HKCA 3T0LA 4DHPA 2NPMA 3O8IA 3SMOA 4FL5A 3SP5A 2BR9A 3M50A 3UBWA 3UX0A 4DNKA 5J31A 4JDDA 1S2XA 2V7DA 1YZ5A 5LHOA 4QX0A 1I5PA 2O02A 4O46A 5BTVA 5HF3A 2C63A 4Y3BA 4ZQ0A 1O9EA 1JI6A 3CQCA 1A4OA 4W8JA 5LX2A 3P1QA 3NKXA 3M51A 5F74A 4N84A 2C9KA 4GNTA 5BY9A 4DHMA 3EB7A 4N7YA 4WRQA 4ARXA 3IQJA 4DAUA 5LU2A 4DHNA 4J6SA 1YWTA 4DATA 5D2DA 1O9FA 1CIYA 4IEAA 2B05A 4FJ3A 3IQUA 4DHQA 3IQVA 3SPRA 2C23A 4QLIA 3CU8A 3T0MA 2C74A 1A37A 3SMKA 3I4RA 5LU1A 4DHOA 2C1NA 2C1JA 4BG6A 4ZDRA 3UALA 4IHLA 3RDHA 4F7RA 3U9XA 4FR3A 3LW1A 1URJA 1QJBA 4DHSA 1A38A 1QJAA 3X0UA 5LVZA 2O8PA 1DLCA 3P1OA 4DHUA 3EFZA 3P1RA 1O9DA 3SMLA 1W99A 2O98A 1IB1A 3P1NA 2BTPA 4DHRA 5IQPA 4Y32A 3ZHEB 4QX1A 5D3FA 2BQ0A 3SMMA 4ARYA 4QX3A 4DHTA 4D8MA 1O9CA 5EWZA 4Y5IA 4MOAA 5D3EA 3MHRA 4DX0A 3AXYC 4E2EA 3P1SA 3CQGA 3E6YA 4JC3A 3UZDA
chains in the Genus database with same CATH topology
2WH0A 3SMNA 4N7GA 3P1PA 4HKCA 3T0LA 4DHPA 2NPMA 3O8IA 3SMOA 4FL5A 3SP5A 2BR9A 3M50A 3UBWA 3UX0A 4DNKA 5J31A 4JDDA 2V7DA 1YZ5A 5LHOA 2O02A 4O46A 5BTVA 5HF3A 2C63A 4Y3BA 4ZQ0A 1O9EA 1A4OA 5LX2A 3P1QA 3NKXA 3M51A 5F74A 4N84A 4GNTA 5BY9A 4DHMA 4N7YA 4WRQA 3IQJA 4DAUA 5LU2A 4DHNA 4J6SA 1YWTA 4DATA 5D2DA 1O9FA 4IEAA 2B05A 4FJ3A 3IQUA 4DHQA 3IQVA 3SPRA 2C23A 4QLIA 3CU8A 3T0MA 2C74A 1A37A 3SMKA 5LU1A 4DHOA 2C1NA 2C1JA 4BG6A 4ZDRA 3UALA 4IHLA 3RDHA 4F7RA 3U9XA 4FR3A 3LW1A 1QJBA 4DHSA 1A38A 1QJAA 5LVZA 2O8PA 3P1OA 4DHUA 3EFZA 3P1RA 1O9DA 3SMLA 2O98A 3P1NA 1IB1A 2BTPA 4DHRA 5IQPA 4Y32A 5D3FA 2BQ0A 3SMMA 4DHTA 1O9CA 5EWZA 4Y5IA 5D3EA 3MHRA 4DX0A 3AXYC 4E2EA 3P1SA 5EXAA 3E6YA 4JC3A 3UZDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WH0 A;  3SMN A;  4N7G A;  3P1P A;  4HKC A;  3T0L A;  4DHP A;  2NPM A;  3O8I A;  3SMO A;  4FL5 A;  3SP5 A;  2BR9 A;  3M50 A;  3UBW A;  3UX0 A;  4DNK A;  5J31 A;  4JDD A;  2V7D A;  1YZ5 A;  5LHO A;  2O02 A;  4O46 A;  5BTV A;  5HF3 A;  2C63 A;  4Y3B A;  4ZQ0 A;  1O9E A;  1A4O A;  5LX2 A;  3P1Q A;  3NKX A;  3M51 A;  5F74 A;  4N84 A;  4GNT A;  5BY9 A;  4DHM A;  4N7Y A;  4WRQ A;  3IQJ A;  4DAU A;  5LU2 A;  4DHN A;  4J6S A;  1YWT A;  4DAT A;  5D2D A;  1O9F A;  4IEA A;  2B05 A;  4FJ3 A;  3IQU A;  4DHQ A;  3IQV A;  3SPR A;  2C23 A;  4QLI A;  3CU8 A;  3T0M A;  2C74 A;  1A37 A;  3SMK A;  5LU1 A;  4DHO A;  2C1N A;  2C1J A;  4BG6 A;  4ZDR A;  3UAL A;  4IHL A;  3RDH A;  4F7R A;  3U9X A;  4FR3 A;  3LW1 A;  1QJB A;  4DHS A;  1A38 A;  1QJA A;  5LVZ A;  2O8P A;  3P1O A;  4DHU A;  3EFZ A;  3P1R A;  1O9D A;  3SML A;  2O98 A;  3P1N A;  1IB1 A;  2BTP A;  4DHR A;  5IQP A;  4Y32 A;  5D3F A;  2BQ0 A;  3SMM A;  4DHT A;  1O9C A;  5EWZ A;  4Y5I A;  5D3E A;  3MHR A;  4DX0 A;  3AXY C;  4E2E A;  3P1S A;  5EXA A;  3E6Y A;  4JC3 A;  3UZD A; 
#chains in the Genus database with same CATH topology
 2WH0 A;  3SMN A;  4N7G A;  4QX2 A;  3P1P A;  5EXA A;  4HKC A;  3T0L A;  4DHP A;  2NPM A;  3O8I A;  3SMO A;  4FL5 A;  3SP5 A;  2BR9 A;  3M50 A;  3UBW A;  3UX0 A;  4DNK A;  5J31 A;  4JDD A;  1S2X A;  2V7D A;  1YZ5 A;  5LHO A;  4QX0 A;  1I5P A;  2O02 A;  4O46 A;  5BTV A;  5HF3 A;  2C63 A;  4Y3B A;  4ZQ0 A;  1O9E A;  1JI6 A;  3CQC A;  1A4O A;  4W8J A;  5LX2 A;  3P1Q A;  3NKX A;  3M51 A;  5F74 A;  4N84 A;  2C9K A;  4GNT A;  5BY9 A;  4DHM A;  3EB7 A;  4N7Y A;  4WRQ A;  4ARX A;  3IQJ A;  4DAU A;  5LU2 A;  4DHN A;  4J6S A;  1YWT A;  4DAT A;  5D2D A;  1O9F A;  1CIY A;  4IEA A;  2B05 A;  4FJ3 A;  3IQU A;  4DHQ A;  3IQV A;  3SPR A;  2C23 A;  4QLI A;  3CU8 A;  3T0M A;  2C74 A;  1A37 A;  3SMK A;  3I4R A;  5LU1 A;  4DHO A;  2C1N A;  2C1J A;  4BG6 A;  4ZDR A;  3UAL A;  4IHL A;  3RDH A;  4F7R A;  3U9X A;  4FR3 A;  3LW1 A;  1URJ A;  1QJB A;  4DHS A;  1A38 A;  1QJA A;  3X0U A;  5LVZ A;  2O8P A;  1DLC A;  3P1O A;  4DHU A;  3EFZ A;  3P1R A;  1O9D A;  3SML A;  1W99 A;  2O98 A;  1IB1 A;  3P1N A;  2BTP A;  4DHR A;  5IQP A;  4Y32 A;  3ZHE B;  4QX1 A;  5D3F A;  2BQ0 A;  3SMM A;  4ARY A;  4QX3 A;  4DHT A;  4D8M A;  1O9C A;  5EWZ A;  4Y5I A;  4MOA A;  5D3E A;  3MHR A;  4DX0 A;  3AXY C;  4E2E A;  3P1S A;  3CQG A;  3E6Y A;  4JC3 A;  3UZD A; 
#chains in the Genus database with same CATH homology
 2WH0 A;  3SMN A;  4N7G A;  3P1P A;  4HKC A;  3T0L A;  4DHP A;  2NPM A;  3O8I A;  3SMO A;  4FL5 A;  3SP5 A;  2BR9 A;  3M50 A;  3UBW A;  3UX0 A;  4DNK A;  5J31 A;  4JDD A;  2V7D A;  1YZ5 A;  5LHO A;  2O02 A;  4O46 A;  5BTV A;  5HF3 A;  2C63 A;  4Y3B A;  4ZQ0 A;  1O9E A;  1A4O A;  5LX2 A;  3P1Q A;  3NKX A;  3M51 A;  5F74 A;  4N84 A;  4GNT A;  5BY9 A;  4DHM A;  4N7Y A;  4WRQ A;  3IQJ A;  4DAU A;  5LU2 A;  4DHN A;  4J6S A;  1YWT A;  4DAT A;  5D2D A;  1O9F A;  4IEA A;  2B05 A;  4FJ3 A;  3IQU A;  4DHQ A;  3IQV A;  3SPR A;  2C23 A;  4QLI A;  3CU8 A;  3T0M A;  2C74 A;  1A37 A;  3SMK A;  5LU1 A;  4DHO A;  2C1N A;  2C1J A;  4BG6 A;  4ZDR A;  3UAL A;  4IHL A;  3RDH A;  4F7R A;  3U9X A;  4FR3 A;  3LW1 A;  1QJB A;  4DHS A;  1A38 A;  1QJA A;  5LVZ A;  2O8P A;  3P1O A;  4DHU A;  3EFZ A;  3P1R A;  1O9D A;  3SML A;  2O98 A;  3P1N A;  1IB1 A;  2BTP A;  4DHR A;  5IQP A;  4Y32 A;  5D3F A;  2BQ0 A;  3SMM A;  4DHT A;  1O9C A;  5EWZ A;  4Y5I A;  5D3E A;  3MHR A;  4DX0 A;  3AXY C;  4E2E A;  3P1S A;  5EXA A;  3E6Y A;  4JC3 A;  3UZD A; 
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similar chains in the Genus database (?% sequence similarity)
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