2O02 | Genus

Total Genus 99

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	99
sequence length	230
structure length	224
Chain Sequence	MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTS

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Protein binding/toxin
source organism	Homo sapiens
publication title	Phosphorylation-independent interaction between 14-3-3 and exoenzyme S: from structure to pathogenesis pubmed doi rcsb
molecule keywords	14-3-3 protein zeta/delta
total genus	99
structure length	224
sequence length	230
chains with identical sequence	B
ec nomenclature
pdb deposition date	2006-11-27

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00244	14-3-3	14-3-3 protein

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.190.20	Mainly Alpha	Up-down Bundle	Delta-Endotoxin; domain 1	14-3-3 domain	2o02A00

3O8IA 3SMNA 4DHMA 1IB1A 3SMOA 1A4OA 2O02A 5LHOA 4DHRA 3EFZA 2WH0A 5LVZA 3SMKA 3UX0A 4WRQA 3M51A 1QJAA 4DHNA 5LU1A 4ZQ0A 5LU2A 2O8PA 4DNKA 3P1NA 2BR9A 3LW1A 4DATA 4Y5IA 3MHRA 3UZDA 2O98A 5EXAA 3M50A 3NKXA 4FJ3A 5D3FA 4GNTA 4DHOA 3RDHA 2BTPA 4FL5A 4N7GA 3E6YA 4N84A 3IQUA 4DX0A 3P1SA 5D3EA 4JC3A 2C23A 5F74A 3IQVA 1O9CA 1YZ5A 4DHSA 3T0MA 2V7DA 4N7YA 4JDDA 3IQJA 1O9FA 1A37A 4DHPA 2BQ0A 4IEAA 4E2EA 4HKCA 4ZDRA 5BTVA 3SMMA 4BG6A 4F7RA 4QLIA 2C1NA 1QJBA 3CU8A 2NPMA 4Y32A 4J6SA 3UALA 4Y3BA 3SP5A 4DHUA 2C74A 5J31A 4DHTA 3P1PA 4IHLA 3AXYC 1A38A 5D2DA 4DHQA 3P1RA 3U9XA 5IQPA 5HF3A 3UBWA 5BY9A 4FR3A 2B05A 5EWZA 3T0LA 3SPRA 4O46A 1O9DA 3SMLA 5LX2A 2C1JA 3P1OA 3P1QA 2C63A 1YWTA 4DAUA 1O9EA
chains in the Genus database with same CATH superfamily

3O8IA 3SMNA 4DHMA 1IB1A 3SMOA 1A4OA 2O02A 4ARXA 5LHOA 4DHRA 3EFZA 2WH0A 1S2XA 4DAUA 5LVZA 4QX3A 3SMKA 3UX0A 3X0UA 3CQCA 4WRQA 3M51A 1QJAA 4DHNA 1DLCA 4ZQ0A 5LU1A 5LU2A 2O8PA 4DNKA 3P1NA 1CIYA 2BR9A 3LW1A 4DATA 4Y5IA 3MHRA 3UZDA 2O98A 5EXAA 3M50A 1URJA 3NKXA 4FJ3A 5D3FA 4GNTA 4DHOA 3RDHA 2BTPA 4FL5A 4N7GA 3E6YA 4N84A 3IQUA 3CQGA 2C9KA 4DX0A 3P1SA 5D3EA 4JC3A 2C23A 5F74A 3IQVA 1O9CA 1YZ5A 4DHSA 3T0MA 2V7DA 4N7YA 4JDDA 3IQJA 1O9FA 4QX2A 1W99A 1A37A 4MOAA 4DHPA 2BQ0A 4IEAA 4E2EA 4HKCA 4ZDRA 5BTVA 3SMMA 4BG6A 4F7RA 4QLIA 2C1NA 1QJBA 3CU8A 1I5PA 4QX1A 2NPMA 4Y32A 4J6SA 4W8JA 4Y3BA 3SP5A 3UALA 2C74A 4DHUA 5J31A 4DHTA 4ARYA 3P1PA 4IHLA 3AXYC 4D8MA 1A38A 5D2DA 4DHQA 3P1RA 3U9XA 5IQPA 5HF3A 3UBWA 5BY9A 4FR3A 2B05A 5EWZA 3T0LA 3SPRA 4O46A 3I4RA 1O9DA 4QX0A 3SMLA 5LX2A 2C1JA 3P1OA 3P1QA 3ZHEB 1JI6A 2C63A 1YWTA 3EB7A 1O9EA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3O8I A;  3SMN A;  4DHM A;  1IB1 A;  3SMO A;  1A4O A;  2O02 A;  5LHO A;  4DHR A;  3EFZ A;  2WH0 A;  5LVZ A;  3SMK A;  3UX0 A;  4WRQ A;  3M51 A;  1QJA A;  4DHN A;  5LU1 A;  4ZQ0 A;  5LU2 A;  2O8P A;  4DNK A;  3P1N A;  2BR9 A;  3LW1 A;  4DAT A;  4Y5I A;  3MHR A;  3UZD A;  2O98 A;  5EXA A;  3M50 A;  3NKX A;  4FJ3 A;  5D3F A;  4GNT A;  4DHO A;  3RDH A;  2BTP A;  4FL5 A;  4N7G A;  3E6Y A;  4N84 A;  3IQU A;  4DX0 A;  3P1S A;  5D3E A;  4JC3 A;  2C23 A;  5F74 A;  3IQV A;  1O9C A;  1YZ5 A;  4DHS A;  3T0M A;  2V7D A;  4N7Y A;  4JDD A;  3IQJ A;  1O9F A;  1A37 A;  4DHP A;  2BQ0 A;  4IEA A;  4E2E A;  4HKC A;  4ZDR A;  5BTV A;  3SMM A;  4BG6 A;  4F7R A;  4QLI A;  2C1N A;  1QJB A;  3CU8 A;  2NPM A;  4Y32 A;  4J6S A;  3UAL A;  4Y3B A;  3SP5 A;  4DHU A;  2C74 A;  5J31 A;  4DHT A;  3P1P A;  4IHL A;  3AXY C;  1A38 A;  5D2D A;  4DHQ A;  3P1R A;  3U9X A;  5IQP A;  5HF3 A;  3UBW A;  5BY9 A;  4FR3 A;  2B05 A;  5EWZ A;  3T0L A;  3SPR A;  4O46 A;  1O9D A;  3SML A;  5LX2 A;  2C1J A;  3P1O A;  3P1Q A;  2C63 A;  1YWT A;  4DAU A;  1O9E A; 
#chains in the Genus database with same CATH topology
 3O8I A;  3SMN A;  4DHM A;  1IB1 A;  3SMO A;  1A4O A;  2O02 A;  4ARX A;  5LHO A;  4DHR A;  3EFZ A;  2WH0 A;  1S2X A;  4DAU A;  5LVZ A;  4QX3 A;  3SMK A;  3UX0 A;  3X0U A;  3CQC A;  4WRQ A;  3M51 A;  1QJA A;  4DHN A;  1DLC A;  4ZQ0 A;  5LU1 A;  5LU2 A;  2O8P A;  4DNK A;  3P1N A;  1CIY A;  2BR9 A;  3LW1 A;  4DAT A;  4Y5I A;  3MHR A;  3UZD A;  2O98 A;  5EXA A;  3M50 A;  1URJ A;  3NKX A;  4FJ3 A;  5D3F A;  4GNT A;  4DHO A;  3RDH A;  2BTP A;  4FL5 A;  4N7G A;  3E6Y A;  4N84 A;  3IQU A;  3CQG A;  2C9K A;  4DX0 A;  3P1S A;  5D3E A;  4JC3 A;  2C23 A;  5F74 A;  3IQV A;  1O9C A;  1YZ5 A;  4DHS A;  3T0M A;  2V7D A;  4N7Y A;  4JDD A;  3IQJ A;  1O9F A;  4QX2 A;  1W99 A;  1A37 A;  4MOA A;  4DHP A;  2BQ0 A;  4IEA A;  4E2E A;  4HKC A;  4ZDR A;  5BTV A;  3SMM A;  4BG6 A;  4F7R A;  4QLI A;  2C1N A;  1QJB A;  3CU8 A;  1I5P A;  4QX1 A;  2NPM A;  4Y32 A;  4J6S A;  4W8J A;  4Y3B A;  3SP5 A;  3UAL A;  2C74 A;  4DHU A;  5J31 A;  4DHT A;  4ARY A;  3P1P A;  4IHL A;  3AXY C;  4D8M A;  1A38 A;  5D2D A;  4DHQ A;  3P1R A;  3U9X A;  5IQP A;  5HF3 A;  3UBW A;  5BY9 A;  4FR3 A;  2B05 A;  5EWZ A;  3T0L A;  3SPR A;  4O46 A;  3I4R A;  1O9D A;  4QX0 A;  3SML A;  5LX2 A;  2C1J A;  3P1O A;  3P1Q A;  3ZHE B;  1JI6 A;  2C63 A;  1YWT A;  3EB7 A;  1O9E A; 
#chains in the Genus database with same CATH homology
 3O8I A;  3SMN A;  4DHM A;  1IB1 A;  3SMO A;  1A4O A;  2O02 A;  5LHO A;  4DHR A;  3EFZ A;  2WH0 A;  5LVZ A;  3SMK A;  3UX0 A;  4WRQ A;  3M51 A;  1QJA A;  4DHN A;  5LU1 A;  4ZQ0 A;  5LU2 A;  2O8P A;  4DNK A;  3P1N A;  2BR9 A;  3LW1 A;  4DAT A;  4Y5I A;  3MHR A;  3UZD A;  2O98 A;  5EXA A;  3M50 A;  3NKX A;  4FJ3 A;  5D3F A;  4GNT A;  4DHO A;  3RDH A;  2BTP A;  4FL5 A;  4N7G A;  3E6Y A;  4N84 A;  3IQU A;  4DX0 A;  3P1S A;  5D3E A;  4JC3 A;  2C23 A;  5F74 A;  3IQV A;  1O9C A;  1YZ5 A;  4DHS A;  3T0M A;  2V7D A;  4N7Y A;  4JDD A;  3IQJ A;  1O9F A;  1A37 A;  4DHP A;  2BQ0 A;  4IEA A;  4E2E A;  4HKC A;  4ZDR A;  5BTV A;  3SMM A;  4BG6 A;  4F7R A;  4QLI A;  2C1N A;  1QJB A;  3CU8 A;  2NPM A;  4Y32 A;  4J6S A;  3UAL A;  4Y3B A;  3SP5 A;  4DHU A;  2C74 A;  5J31 A;  4DHT A;  3P1P A;  4IHL A;  3AXY C;  1A38 A;  5D2D A;  4DHQ A;  3P1R A;  3U9X A;  5IQP A;  5HF3 A;  3UBW A;  5BY9 A;  4FR3 A;  2B05 A;  5EWZ A;  3T0L A;  3SPR A;  4O46 A;  1O9D A;  3SML A;  5LX2 A;  2C1J A;  3P1O A;  3P1Q A;  2C63 A;  1YWT A;  4DAU A;  1O9E A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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2O02A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations