2O02 | Genus

Total Genus 99

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	99
sequence length	230
structure length	224
Chain Sequence	MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTS

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Phosphorylation-independent interaction between 14-3-3 and exoenzyme S: from structure to pathogenesis pubmed doi rcsb
molecule keywords	14-3-3 protein zeta/delta
molecule tags	Protein binding/toxin
source organism	Homo sapiens
total genus	99
structure length	224
sequence length	230
chains with identical sequence	B
ec nomenclature
pdb deposition date	2006-11-27

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00244	14-3-3	14-3-3 protein

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.190.20	Mainly Alpha	Up-down Bundle	Delta-Endotoxin; domain 1	14-3-3 domain	2o02A00

3P1SA 4DAUA 3SMOA 5BY9A 3IQVA 3E6YA 4ZDRA 2O8PA 4DHPA 5EXAA 4DHTA 2C23A 3UX0A 4JDDA 2BR9A 3NKXA 3UALA 3MHRA 5BTVA 4N84A 3RDHA 2BTPA 4IEAA 2C74A 1YZ5A 3UBWA 2BQ0A 1A37A 3M50A 4J6SA 5F74A 1YWTA 3IQJA 3P1RA 5D3EA 3SMMA 3P1PA 4DNKA 2O98A 3U9XA 1O9FA 4JC3A 5HF3A 3LW1A 4ZQ0A 4Y32A 5LX2A 3T0MA 4HKCA 3UZDA 1IB1A 3P1QA 4QLIA 4DHQA 5LU2A 3IQUA 1O9DA 4GNTA 3M51A 1A38A 2B05A 2C1NA 4FR3A 4DHUA 3AXYC 4FJ3A 1QJAA 3P1OA 3EFZA 5J31A 4DHRA 4FL5A 2O02A 3SMNA 5LU1A 1O9EA 3P1NA 1QJBA 4Y3BA 4DHMA 4F7RA 4DHSA 3SPRA 4DHOA 3T0LA 2C1JA 5EWZA 3SMLA 4IHLA 2C63A 4DHNA 5IQPA 4N7YA 1O9CA 4BG6A 2NPMA 4DX0A 4WRQA 5D3FA 1A4OA 4DATA 5LHOA 3O8IA 3SMKA 4O46A 5LVZA 3CU8A 4Y5IA 2V7DA 4E2EA 5D2DA 3SP5A 2WH0A 4N7GA
chains in the Genus database with same CATH superfamily

3P1SA 4DAUA 1URJA 3SMOA 1DLCA 5BY9A 3IQVA 3E6YA 4QX3A 4ZDRA 2O8PA 4DHPA 5EXAA 4DHTA 2C23A 3UX0A 4JDDA 2BR9A 3NKXA 3UALA 3MHRA 4QX1A 5BTVA 4N84A 3RDHA 2BTPA 4IEAA 2C74A 1CIYA 1YZ5A 3UBWA 2BQ0A 1A37A 4ARYA 3M50A 4J6SA 5F74A 1YWTA 3IQJA 3P1RA 5D3EA 3SMMA 3I4RA 3P1PA 4DNKA 2O98A 3U9XA 1O9FA 4JC3A 5HF3A 3CQGA 1I5PA 3LW1A 4ZQ0A 4Y32A 5LX2A 1JI6A 3T0MA 4HKCA 3UZDA 1IB1A 3P1QA 4QLIA 4DHQA 3CQCA 5LU2A 3IQUA 1O9DA 4MOAA 4GNTA 3ZHEB 3M51A 1A38A 3X0UA 2B05A 2C1NA 4FR3A 4DHUA 3AXYC 4FJ3A 1QJAA 3P1OA 3EFZA 5J31A 3EB7A 1S2XA 4DHRA 4FL5A 2O02A 3SMNA 5LU1A 1O9EA 3P1NA 1QJBA 4Y3BA 4D8MA 4DHMA 4F7RA 4DHSA 4W8JA 3SPRA 4QX2A 4DHOA 3T0LA 4ARXA 2C1JA 5EWZA 3SMLA 4IHLA 2C63A 4DHNA 5IQPA 4N7YA 1O9CA 4BG6A 2NPMA 4DX0A 4WRQA 5D3FA 1W99A 1A4OA 4DATA 5LHOA 3O8IA 3SMKA 2C9KA 4QX0A 4O46A 5LVZA 3CU8A 4Y5IA 2V7DA 4E2EA 5D2DA 3SP5A 2WH0A 4N7GA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3P1S A;  4DAU A;  3SMO A;  5BY9 A;  3IQV A;  3E6Y A;  4ZDR A;  2O8P A;  4DHP A;  5EXA A;  4DHT A;  2C23 A;  3UX0 A;  4JDD A;  2BR9 A;  3NKX A;  3UAL A;  3MHR A;  5BTV A;  4N84 A;  3RDH A;  2BTP A;  4IEA A;  2C74 A;  1YZ5 A;  3UBW A;  2BQ0 A;  1A37 A;  3M50 A;  4J6S A;  5F74 A;  1YWT A;  3IQJ A;  3P1R A;  5D3E A;  3SMM A;  3P1P A;  4DNK A;  2O98 A;  3U9X A;  1O9F A;  4JC3 A;  5HF3 A;  3LW1 A;  4ZQ0 A;  4Y32 A;  5LX2 A;  3T0M A;  4HKC A;  3UZD A;  1IB1 A;  3P1Q A;  4QLI A;  4DHQ A;  5LU2 A;  3IQU A;  1O9D A;  4GNT A;  3M51 A;  1A38 A;  2B05 A;  2C1N A;  4FR3 A;  4DHU A;  3AXY C;  4FJ3 A;  1QJA A;  3P1O A;  3EFZ A;  5J31 A;  4DHR A;  4FL5 A;  2O02 A;  3SMN A;  5LU1 A;  1O9E A;  3P1N A;  1QJB A;  4Y3B A;  4DHM A;  4F7R A;  4DHS A;  3SPR A;  4DHO A;  3T0L A;  2C1J A;  5EWZ A;  3SML A;  4IHL A;  2C63 A;  4DHN A;  5IQP A;  4N7Y A;  1O9C A;  4BG6 A;  2NPM A;  4DX0 A;  4WRQ A;  5D3F A;  1A4O A;  4DAT A;  5LHO A;  3O8I A;  3SMK A;  4O46 A;  5LVZ A;  3CU8 A;  4Y5I A;  2V7D A;  4E2E A;  5D2D A;  3SP5 A;  2WH0 A;  4N7G A; 
#chains in the Genus database with same CATH topology
 3P1S A;  4DAU A;  1URJ A;  3SMO A;  1DLC A;  5BY9 A;  3IQV A;  3E6Y A;  4QX3 A;  4ZDR A;  2O8P A;  4DHP A;  5EXA A;  4DHT A;  2C23 A;  3UX0 A;  4JDD A;  2BR9 A;  3NKX A;  3UAL A;  3MHR A;  4QX1 A;  5BTV A;  4N84 A;  3RDH A;  2BTP A;  4IEA A;  2C74 A;  1CIY A;  1YZ5 A;  3UBW A;  2BQ0 A;  1A37 A;  4ARY A;  3M50 A;  4J6S A;  5F74 A;  1YWT A;  3IQJ A;  3P1R A;  5D3E A;  3SMM A;  3I4R A;  3P1P A;  4DNK A;  2O98 A;  3U9X A;  1O9F A;  4JC3 A;  5HF3 A;  3CQG A;  1I5P A;  3LW1 A;  4ZQ0 A;  4Y32 A;  5LX2 A;  1JI6 A;  3T0M A;  4HKC A;  3UZD A;  1IB1 A;  3P1Q A;  4QLI A;  4DHQ A;  3CQC A;  5LU2 A;  3IQU A;  1O9D A;  4MOA A;  4GNT A;  3ZHE B;  3M51 A;  1A38 A;  3X0U A;  2B05 A;  2C1N A;  4FR3 A;  4DHU A;  3AXY C;  4FJ3 A;  1QJA A;  3P1O A;  3EFZ A;  5J31 A;  3EB7 A;  1S2X A;  4DHR A;  4FL5 A;  2O02 A;  3SMN A;  5LU1 A;  1O9E A;  3P1N A;  1QJB A;  4Y3B A;  4D8M A;  4DHM A;  4F7R A;  4DHS A;  4W8J A;  3SPR A;  4QX2 A;  4DHO A;  3T0L A;  4ARX A;  2C1J A;  5EWZ A;  3SML A;  4IHL A;  2C63 A;  4DHN A;  5IQP A;  4N7Y A;  1O9C A;  4BG6 A;  2NPM A;  4DX0 A;  4WRQ A;  5D3F A;  1W99 A;  1A4O A;  4DAT A;  5LHO A;  3O8I A;  3SMK A;  2C9K A;  4QX0 A;  4O46 A;  5LVZ A;  3CU8 A;  4Y5I A;  2V7D A;  4E2E A;  5D2D A;  3SP5 A;  2WH0 A;  4N7G A; 
#chains in the Genus database with same CATH homology
 3P1S A;  4DAU A;  3SMO A;  5BY9 A;  3IQV A;  3E6Y A;  4ZDR A;  2O8P A;  4DHP A;  5EXA A;  4DHT A;  2C23 A;  3UX0 A;  4JDD A;  2BR9 A;  3NKX A;  3UAL A;  3MHR A;  5BTV A;  4N84 A;  3RDH A;  2BTP A;  4IEA A;  2C74 A;  1YZ5 A;  3UBW A;  2BQ0 A;  1A37 A;  3M50 A;  4J6S A;  5F74 A;  1YWT A;  3IQJ A;  3P1R A;  5D3E A;  3SMM A;  3P1P A;  4DNK A;  2O98 A;  3U9X A;  1O9F A;  4JC3 A;  5HF3 A;  3LW1 A;  4ZQ0 A;  4Y32 A;  5LX2 A;  3T0M A;  4HKC A;  3UZD A;  1IB1 A;  3P1Q A;  4QLI A;  4DHQ A;  5LU2 A;  3IQU A;  1O9D A;  4GNT A;  3M51 A;  1A38 A;  2B05 A;  2C1N A;  4FR3 A;  4DHU A;  3AXY C;  4FJ3 A;  1QJA A;  3P1O A;  3EFZ A;  5J31 A;  4DHR A;  4FL5 A;  2O02 A;  3SMN A;  5LU1 A;  1O9E A;  3P1N A;  1QJB A;  4Y3B A;  4DHM A;  4F7R A;  4DHS A;  3SPR A;  4DHO A;  3T0L A;  2C1J A;  5EWZ A;  3SML A;  4IHL A;  2C63 A;  4DHN A;  5IQP A;  4N7Y A;  1O9C A;  4BG6 A;  2NPM A;  4DX0 A;  4WRQ A;  5D3F A;  1A4O A;  4DAT A;  5LHO A;  3O8I A;  3SMK A;  4O46 A;  5LVZ A;  3CU8 A;  4Y5I A;  2V7D A;  4E2E A;  5D2D A;  3SP5 A;  2WH0 A;  4N7G A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2O02A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations