2QEXW

Negamycin binds to the wall of the nascent chain exit tunnel of the 50s ribosomal subunit
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Negamycin binds to the wall of the nascent chain exit tunnel of the 50S ribosomal subunit.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 48
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2007-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 2qexW02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 2qexW01
1YHQW 1K9MX 4U67W 3CCVW 5GADa 3OW2V 1YI2W 1Q7YX 3CC2W 1K73X 3CCJW 2OTLW 1M90X 5GAEa 3PIPW 1VQ9W 1VQ4W 3CCLW 3PIOW 1VQ8W 4UY8Z 5DM7W 5GAGa 1K8AX 1Q81X 4IO9W 3CC4W 1NJIX 4IOCW 1VQOW 1S72W 2ZJPW 3CCSW 1VQPW 1N8RX 1KD1X 5JVHW 3CC7W 1YJWW 3G6EW 3G4SW 3J7ZZ 4WFAW 1VQ6W 1YJNW 3CD6W 2ZJQW 5JVGW 3CCEW 1YIJW 1BXYA 3CF5W 4IOAW 1JJ2V 4WF9W 1Q82X 1VQLW 3CPWV 3CMAW 3CCUW 1VQNW 3G71W 2QA4W 5GAHa 1YJ9W 1QVGV 1VQ5W 3CXCV 1Q86X 2ZJRW 1KC8X 4WFNW 2QEXW 5DM6W 2OTJW 1VQ7W 4WCEW 1M1KX 1KQSV 3I55W 3CCMW 3I56W 1VQKW 3CCQW 4WFBW 1QVFV 1YITW 1W2BV 3CCRW 3CMEW 1VQMW 3DLLW 5HL7W
chains in the Genus database with same CATH superfamily
1YHQW 1K9MX 4U67W 1MWRA 1MBUC 4YJMA 4CPKA 3W7UA 3D3IA 1DD4A 3CCVW 3OW2V 1Q7YX 1YI2W 5GADa 3CC2W 1K73X 3CCJW 2OTLW 1MWSA 1M90X 5GAEa 3G1BA 3PIPW 1VQ9W 3G3PA 1VQ4W 3CCLW 3PIOW 1VQ8W 4UY8Z 1MWUA 5CA3A 1MBXC 5DM7W 5GW7A 3W7WA 5GAGa 1MWTA 1MG9A 3DNJA 1K8AX 3G19A 3O1FA 1Q81X 4IO9W 3ZG0A 1DD3A 3CC4W 5M18A 1NJIX 4IOCW 1VQOW 1S72W 2ZJPW 3CCSW 1VQPW 1N8RX 1KD1X 5JVHW 3O2OA 3CC7W 3ZG5A 1YJWW 4CJNA 3G6EW 3G4SW 2W9RA 3J7ZZ 4WFAW 5M19A 1VQ6W 1MBVB 4BL3A 1YJNW 1R6OC 3CD6W 3O2BA 3ZFZA 2ZJQW 5JVGW 3O2HA 2WA9A 3CCEW 1YIJW 1BXYA 4BL2A 1CTFA 3CF5W 4IOAW 4DKIA 3W7SA 1JJ2V 2WA8A 4WF9W 1Q82X 3GQ1A 1VQLW 3CPWV 3CMAW 3GQ0A 1R6QC 3CCUW 1VQNW 3W7XA 3G71W 2QA4W 1YJ9W 1RQSA 1QVGV 3W7TA 5GAHa 1VQ5W 3CXCV 1Q86X 2ZJRW 1KC8X 4WFNW 2QEXW 4YKAA 5DM6W 2OTJW 1VQ7W 4WCEW 1M1KX 1KQSV 3I55W 3CCMW 3I56W 1VQKW 3CCQW 4YJXA 1VQQA 4WFBW 5M1AA 1QVFV 1YITW 1LZWA 1W2BV 3CCRW 3GW1A 3O1FB 3CMEW 1RQVA 1VQMW 4C1NA 3DLLW 1RQUA 5HL7W
chains in the Genus database with same CATH topology
1YHQW 1K9MX 4U67W 3CCVW 5GADa 3OW2V 1YI2W 1Q7YX 3CC2W 1K73X 3CCJW 2OTLW 1M90X 5GAEa 3PIPW 1VQ9W 1VQ4W 3CCLW 3PIOW 1VQ8W 4UY8Z 5DM7W 5GAGa 1K8AX 1Q81X 4IO9W 3CC4W 1NJIX 4IOCW 1VQOW 1S72W 2ZJPW 3CCSW 1VQPW 1N8RX 1KD1X 5JVHW 3CC7W 1YJWW 3G6EW 3G4SW 3J7ZZ 4WFAW 1VQ6W 1YJNW 3CD6W 2ZJQW 5JVGW 3CCEW 1YIJW 1BXYA 3CF5W 4IOAW 1JJ2V 4WF9W 1Q82X 1VQLW 3CPWV 3CMAW 3CCUW 1VQNW 3G71W 2QA4W 5GAHa 1YJ9W 1QVGV 1VQ5W 3CXCV 1Q86X 2ZJRW 1KC8X 4WFNW 2QEXW 5DM6W 2OTJW 1VQ7W 4WCEW 1M1KX 1KQSV 3I55W 3CCMW 3I56W 1VQKW 3CCQW 4WFBW 1QVFV 1YITW 1W2BV 3CCRW 3CMEW 1VQMW 4C1NA 3DLLW 5HL7W
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YHQ W;  1K9M X;  4U67 W;  3CCV W;  5GAD a;  3OW2 V;  1YI2 W;  1Q7Y X;  3CC2 W;  1K73 X;  3CCJ W;  2OTL W;  1M90 X;  5GAE a;  3PIP W;  1VQ9 W;  1VQ4 W;  3CCL W;  3PIO W;  1VQ8 W;  4UY8 Z;  5DM7 W;  5GAG a;  1K8A X;  1Q81 X;  4IO9 W;  3CC4 W;  1NJI X;  4IOC W;  1VQO W;  1S72 W;  2ZJP W;  3CCS W;  1VQP W;  1N8R X;  1KD1 X;  5JVH W;  3CC7 W;  1YJW W;  3G6E W;  3G4S W;  3J7Z Z;  4WFA W;  1VQ6 W;  1YJN W;  3CD6 W;  2ZJQ W;  5JVG W;  3CCE W;  1YIJ W;  1BXY A;  3CF5 W;  4IOA W;  1JJ2 V;  4WF9 W;  1Q82 X;  1VQL W;  3CPW V;  3CMA W;  3CCU W;  1VQN W;  3G71 W;  2QA4 W;  5GAH a;  1YJ9 W;  1QVG V;  1VQ5 W;  3CXC V;  1Q86 X;  2ZJR W;  1KC8 X;  4WFN W;  2QEX W;  5DM6 W;  2OTJ W;  1VQ7 W;  4WCE W;  1M1K X;  1KQS V;  3I55 W;  3CCM W;  3I56 W;  1VQK W;  3CCQ W;  4WFB W;  1QVF V;  1YIT W;  1W2B V;  3CCR W;  3CME W;  1VQM W;  3DLL W;  5HL7 W; 
#chains in the Genus database with same CATH topology
 1YHQ W;  1K9M X;  4U67 W;  1MWR A;  1MBU C;  4YJM A;  4CPK A;  3W7U A;  3D3I A;  1DD4 A;  3CCV W;  3OW2 V;  1Q7Y X;  1YI2 W;  5GAD a;  3CC2 W;  1K73 X;  3CCJ W;  2OTL W;  1MWS A;  1M90 X;  5GAE a;  3G1B A;  3PIP W;  1VQ9 W;  3G3P A;  1VQ4 W;  3CCL W;  3PIO W;  1VQ8 W;  4UY8 Z;  1MWU A;  5CA3 A;  1MBX C;  5DM7 W;  5GW7 A;  3W7W A;  5GAG a;  1MWT A;  1MG9 A;  3DNJ A;  1K8A X;  3G19 A;  3O1F A;  1Q81 X;  4IO9 W;  3ZG0 A;  1DD3 A;  3CC4 W;  5M18 A;  1NJI X;  4IOC W;  1VQO W;  1S72 W;  2ZJP W;  3CCS W;  1VQP W;  1N8R X;  1KD1 X;  5JVH W;  3O2O A;  3CC7 W;  3ZG5 A;  1YJW W;  4CJN A;  3G6E W;  3G4S W;  2W9R A;  3J7Z Z;  4WFA W;  5M19 A;  1VQ6 W;  1MBV B;  4BL3 A;  1YJN W;  1R6O C;  3CD6 W;  3O2B A;  3ZFZ A;  2ZJQ W;  5JVG W;  3O2H A;  2WA9 A;  3CCE W;  1YIJ W;  1BXY A;  4BL2 A;  1CTF A;  3CF5 W;  4IOA W;  4DKI A;  3W7S A;  1JJ2 V;  2WA8 A;  4WF9 W;  1Q82 X;  3GQ1 A;  1VQL W;  3CPW V;  3CMA W;  3GQ0 A;  1R6Q C;  3CCU W;  1VQN W;  3W7X A;  3G71 W;  2QA4 W;  1YJ9 W;  1RQS A;  1QVG V;  3W7T A;  5GAH a;  1VQ5 W;  3CXC V;  1Q86 X;  2ZJR W;  1KC8 X;  4WFN W;  2QEX W;  4YKA A;  5DM6 W;  2OTJ W;  1VQ7 W;  4WCE W;  1M1K X;  1KQS V;  3I55 W;  3CCM W;  3I56 W;  1VQK W;  3CCQ W;  4YJX A;  1VQQ A;  4WFB W;  5M1A A;  1QVF V;  1YIT W;  1LZW A;  1W2B V;  3CCR W;  3GW1 A;  3O1F B;  3CME W;  1RQV A;  1VQM W;  4C1N A;  3DLL W;  1RQU A;  5HL7 W; 
#chains in the Genus database with same CATH homology
 1YHQ W;  1K9M X;  4U67 W;  3CCV W;  5GAD a;  3OW2 V;  1YI2 W;  1Q7Y X;  3CC2 W;  1K73 X;  3CCJ W;  2OTL W;  1M90 X;  5GAE a;  3PIP W;  1VQ9 W;  1VQ4 W;  3CCL W;  3PIO W;  1VQ8 W;  4UY8 Z;  5DM7 W;  5GAG a;  1K8A X;  1Q81 X;  4IO9 W;  3CC4 W;  1NJI X;  4IOC W;  1VQO W;  1S72 W;  2ZJP W;  3CCS W;  1VQP W;  1N8R X;  1KD1 X;  5JVH W;  3CC7 W;  1YJW W;  3G6E W;  3G4S W;  3J7Z Z;  4WFA W;  1VQ6 W;  1YJN W;  3CD6 W;  2ZJQ W;  5JVG W;  3CCE W;  1YIJ W;  1BXY A;  3CF5 W;  4IOA W;  1JJ2 V;  4WF9 W;  1Q82 X;  1VQL W;  3CPW V;  3CMA W;  3CCU W;  1VQN W;  3G71 W;  2QA4 W;  5GAH a;  1YJ9 W;  1QVG V;  1VQ5 W;  3CXC V;  1Q86 X;  2ZJR W;  1KC8 X;  4WFN W;  2QEX W;  5DM6 W;  2OTJ W;  1VQ7 W;  4WCE W;  1M1K X;  1KQS V;  3I55 W;  3CCM W;  3I56 W;  1VQK W;  3CCQ W;  4WFB W;  1QVF V;  1YIT W;  1W2B V;  3CCR W;  3CME W;  1VQM W;  4C1N A;  3DLL W;  5HL7 W; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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