2WH0A

Recognition of an intrachain tandem 14-3-3 binding site within protein kinase c epsilon
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
228
structure length
221
Chain Sequence
DKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELSYKDSTLIMQLLRDNLTLWT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Recognition of an Intra-Chain Tandem 14-3-3 Binding Site within Pkc Epsilon.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords 14-3-3 PROTEIN ZETA/DELTA
total genus 94
structure length 221
sequence length 228
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2009-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 2wh0A00
3M50A 3P1SA 2BR9A 1O9EA 4F7RA 2C63A 4DHSA 3UBWA 4FL5A 5BTVA 1A37A 3SP5A 3AXYC 4DHQA 3LW1A 2BQ0A 5LU1A 5J31A 2BTPA 2B05A 3RDHA 4N7GA 3UALA 4DHUA 3P1NA 4FR3A 2V7DA 4DHMA 1QJBA 2C74A 3IQJA 3UX0A 4N7YA 4WRQA 4JDDA 1IB1A 3MHRA 5HF3A 5LX2A 3SMKA 3NKXA 4IEAA 4QLIA 3U9XA 1YZ5A 3P1PA 5D3EA 4Y3BA 3T0LA 4BG6A 2C23A 4Y32A 2WH0A 3SMMA 5F74A 2O8PA 4GNTA 4DAUA 5LVZA 1QJAA 3O8IA 4FJ3A 3IQVA 3EFZA 1O9DA 2C1JA 1A38A 3SMOA 2NPMA 4DHOA 5LHOA 3P1QA 4DHRA 4ZQ0A 3SMNA 4DHNA 4E2EA 3P1RA 5D3FA 4DHPA 1YWTA 2O02A 4N84A 1O9CA 4DATA 4JC3A 4Y5IA 4HKCA 3SMLA 3M51A 4DNKA 5EWZA 5EXAA 4J6SA 4DHTA 1A4OA 4DX0A 3IQUA 4O46A 5BY9A 5D2DA 3E6YA 1O9FA 4ZDRA 3P1OA 2O98A 2C1NA 3SPRA 3UZDA 5IQPA 4IHLA 3CU8A 5LU2A 3T0MA
chains in the Genus database with same CATH superfamily
3M50A 3P1SA 2BR9A 1O9EA 4F7RA 3I4RA 2C63A 4W8JA 4DHSA 3ZHEB 3UBWA 4FL5A 4QX1A 5BTVA 1A37A 3SP5A 3AXYC 4QX0A 4DHQA 3LW1A 1I5PA 2BQ0A 5LU1A 5J31A 1JI6A 2BTPA 2B05A 3RDHA 4N7GA 3UALA 4DHUA 3P1NA 4FR3A 2V7DA 4DHMA 1QJBA 2C74A 3X0UA 3IQJA 3UX0A 4N7YA 4WRQA 4JDDA 1IB1A 1W99A 3MHRA 1URJA 5HF3A 5LX2A 3SMKA 1DLCA 3NKXA 4IEAA 4QLIA 3U9XA 4MOAA 1YZ5A 3P1PA 5D3EA 4Y3BA 3T0LA 1CIYA 4BG6A 2C23A 3CQGA 4Y32A 2WH0A 3SMMA 4QX2A 5F74A 4D8MA 2O8PA 4GNTA 4DAUA 5LVZA 1QJAA 3O8IA 3CQCA 4FJ3A 3IQVA 3EFZA 1O9DA 2C1JA 1A38A 3SMOA 2NPMA 4DHOA 5LHOA 3P1QA 2C9KA 4DHRA 4ZQ0A 3SMNA 4DHNA 4QX3A 4E2EA 3P1RA 4ARYA 5D3FA 4DHPA 1YWTA 2O02A 4N84A 1O9CA 4DATA 4JC3A 4Y5IA 4HKCA 3SMLA 3M51A 4ARXA 4DNKA 5EWZA 3EB7A 1S2XA 5EXAA 4J6SA 4DHTA 1A4OA 4DX0A 3IQUA 4O46A 5BY9A 5D2DA 3E6YA 1O9FA 4ZDRA 3P1OA 2O98A 2C1NA 3SPRA 3UZDA 5IQPA 4IHLA 3CU8A 5LU2A 3T0MA
chains in the Genus database with same CATH topology
3M50A 3P1SA 2BR9A 1O9EA 4F7RA 2C63A 4DHSA 3UBWA 4FL5A 5BTVA 1A37A 3SP5A 3AXYC 4DHQA 3LW1A 2BQ0A 5LU1A 5J31A 2BTPA 2B05A 3RDHA 4N7GA 3UALA 4DHUA 3P1NA 4FR3A 2V7DA 4DHMA 1QJBA 2C74A 3IQJA 3UX0A 4N7YA 4WRQA 4JDDA 1IB1A 3MHRA 5HF3A 5LX2A 3SMKA 3NKXA 4IEAA 4QLIA 3U9XA 1YZ5A 3P1PA 5D3EA 4Y3BA 3T0LA 4BG6A 2C23A 4Y32A 2WH0A 3SMMA 5F74A 2O8PA 4GNTA 4DAUA 5LVZA 1QJAA 3O8IA 4FJ3A 3IQVA 3EFZA 1O9DA 2C1JA 1A38A 3SMOA 2NPMA 4DHOA 5LHOA 3P1QA 4DHRA 4ZQ0A 3SMNA 4DHNA 4E2EA 3P1RA 5D3FA 4DHPA 1YWTA 2O02A 4N84A 1O9CA 4DATA 4JC3A 4Y5IA 4HKCA 3SMLA 3M51A 4DNKA 5EWZA 5EXAA 4J6SA 4DHTA 1A4OA 4DX0A 3IQUA 4O46A 5BY9A 5D2DA 3E6YA 1O9FA 4ZDRA 3P1OA 2O98A 2C1NA 3SPRA 3UZDA 5IQPA 4IHLA 3CU8A 5LU2A 3T0MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3M50 A;  3P1S A;  2BR9 A;  1O9E A;  4F7R A;  2C63 A;  4DHS A;  3UBW A;  4FL5 A;  5BTV A;  1A37 A;  3SP5 A;  3AXY C;  4DHQ A;  3LW1 A;  2BQ0 A;  5LU1 A;  5J31 A;  2BTP A;  2B05 A;  3RDH A;  4N7G A;  3UAL A;  4DHU A;  3P1N A;  4FR3 A;  2V7D A;  4DHM A;  1QJB A;  2C74 A;  3IQJ A;  3UX0 A;  4N7Y A;  4WRQ A;  4JDD A;  1IB1 A;  3MHR A;  5HF3 A;  5LX2 A;  3SMK A;  3NKX A;  4IEA A;  4QLI A;  3U9X A;  1YZ5 A;  3P1P A;  5D3E A;  4Y3B A;  3T0L A;  4BG6 A;  2C23 A;  4Y32 A;  2WH0 A;  3SMM A;  5F74 A;  2O8P A;  4GNT A;  4DAU A;  5LVZ A;  1QJA A;  3O8I A;  4FJ3 A;  3IQV A;  3EFZ A;  1O9D A;  2C1J A;  1A38 A;  3SMO A;  2NPM A;  4DHO A;  5LHO A;  3P1Q A;  4DHR A;  4ZQ0 A;  3SMN A;  4DHN A;  4E2E A;  3P1R A;  5D3F A;  4DHP A;  1YWT A;  2O02 A;  4N84 A;  1O9C A;  4DAT A;  4JC3 A;  4Y5I A;  4HKC A;  3SML A;  3M51 A;  4DNK A;  5EWZ A;  5EXA A;  4J6S A;  4DHT A;  1A4O A;  4DX0 A;  3IQU A;  4O46 A;  5BY9 A;  5D2D A;  3E6Y A;  1O9F A;  4ZDR A;  3P1O A;  2O98 A;  2C1N A;  3SPR A;  3UZD A;  5IQP A;  4IHL A;  3CU8 A;  5LU2 A;  3T0M A; 
#chains in the Genus database with same CATH topology
 3M50 A;  3P1S A;  2BR9 A;  1O9E A;  4F7R A;  3I4R A;  2C63 A;  4W8J A;  4DHS A;  3ZHE B;  3UBW A;  4FL5 A;  4QX1 A;  5BTV A;  1A37 A;  3SP5 A;  3AXY C;  4QX0 A;  4DHQ A;  3LW1 A;  1I5P A;  2BQ0 A;  5LU1 A;  5J31 A;  1JI6 A;  2BTP A;  2B05 A;  3RDH A;  4N7G A;  3UAL A;  4DHU A;  3P1N A;  4FR3 A;  2V7D A;  4DHM A;  1QJB A;  2C74 A;  3X0U A;  3IQJ A;  3UX0 A;  4N7Y A;  4WRQ A;  4JDD A;  1IB1 A;  1W99 A;  3MHR A;  1URJ A;  5HF3 A;  5LX2 A;  3SMK A;  1DLC A;  3NKX A;  4IEA A;  4QLI A;  3U9X A;  4MOA A;  1YZ5 A;  3P1P A;  5D3E A;  4Y3B A;  3T0L A;  1CIY A;  4BG6 A;  2C23 A;  3CQG A;  4Y32 A;  2WH0 A;  3SMM A;  4QX2 A;  5F74 A;  4D8M A;  2O8P A;  4GNT A;  4DAU A;  5LVZ A;  1QJA A;  3O8I A;  3CQC A;  4FJ3 A;  3IQV A;  3EFZ A;  1O9D A;  2C1J A;  1A38 A;  3SMO A;  2NPM A;  4DHO A;  5LHO A;  3P1Q A;  2C9K A;  4DHR A;  4ZQ0 A;  3SMN A;  4DHN A;  4QX3 A;  4E2E A;  3P1R A;  4ARY A;  5D3F A;  4DHP A;  1YWT A;  2O02 A;  4N84 A;  1O9C A;  4DAT A;  4JC3 A;  4Y5I A;  4HKC A;  3SML A;  3M51 A;  4ARX A;  4DNK A;  5EWZ A;  3EB7 A;  1S2X A;  5EXA A;  4J6S A;  4DHT A;  1A4O A;  4DX0 A;  3IQU A;  4O46 A;  5BY9 A;  5D2D A;  3E6Y A;  1O9F A;  4ZDR A;  3P1O A;  2O98 A;  2C1N A;  3SPR A;  3UZD A;  5IQP A;  4IHL A;  3CU8 A;  5LU2 A;  3T0M A; 
#chains in the Genus database with same CATH homology
 3M50 A;  3P1S A;  2BR9 A;  1O9E A;  4F7R A;  2C63 A;  4DHS A;  3UBW A;  4FL5 A;  5BTV A;  1A37 A;  3SP5 A;  3AXY C;  4DHQ A;  3LW1 A;  2BQ0 A;  5LU1 A;  5J31 A;  2BTP A;  2B05 A;  3RDH A;  4N7G A;  3UAL A;  4DHU A;  3P1N A;  4FR3 A;  2V7D A;  4DHM A;  1QJB A;  2C74 A;  3IQJ A;  3UX0 A;  4N7Y A;  4WRQ A;  4JDD A;  1IB1 A;  3MHR A;  5HF3 A;  5LX2 A;  3SMK A;  3NKX A;  4IEA A;  4QLI A;  3U9X A;  1YZ5 A;  3P1P A;  5D3E A;  4Y3B A;  3T0L A;  4BG6 A;  2C23 A;  4Y32 A;  2WH0 A;  3SMM A;  5F74 A;  2O8P A;  4GNT A;  4DAU A;  5LVZ A;  1QJA A;  3O8I A;  4FJ3 A;  3IQV A;  3EFZ A;  1O9D A;  2C1J A;  1A38 A;  3SMO A;  2NPM A;  4DHO A;  5LHO A;  3P1Q A;  4DHR A;  4ZQ0 A;  3SMN A;  4DHN A;  4E2E A;  3P1R A;  5D3F A;  4DHP A;  1YWT A;  2O02 A;  4N84 A;  1O9C A;  4DAT A;  4JC3 A;  4Y5I A;  4HKC A;  3SML A;  3M51 A;  4DNK A;  5EWZ A;  5EXA A;  4J6S A;  4DHT A;  1A4O A;  4DX0 A;  3IQU A;  4O46 A;  5BY9 A;  5D2D A;  3E6Y A;  1O9F A;  4ZDR A;  3P1O A;  2O98 A;  2C1N A;  3SPR A;  3UZD A;  5IQP A;  4IHL A;  3CU8 A;  5LU2 A;  3T0M A; 
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