2WH0A

Recognition of an intrachain tandem 14-3-3 binding site within protein kinase c epsilon
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
228
structure length
221
Chain Sequence
DKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELSYKDSTLIMQLLRDNLTLWT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Recognition of an Intra-Chain Tandem 14-3-3 Binding Site within Pkc Epsilon.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords 14-3-3 PROTEIN ZETA/DELTA
total genus 94
structure length 221
sequence length 228
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2009-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 2wh0A00
4HKCA 5J31A 4ZDRA 3MHRA 4QLIA 3T0MA 4ZQ0A 4J6SA 5D2DA 1A37A 1QJAA 1O9DA 3P1NA 4BG6A 4DHSA 4DHQA 4Y5IA 2C63A 1QJBA 4IHLA 4DX0A 2B05A 4O46A 2NPMA 3SMLA 2O02A 3M51A 5IQPA 4DHUA 5LVZA 5BTVA 3SMNA 4Y32A 4JDDA 3EFZA 4N84A 3U9XA 4DHTA 4IEAA 3IQUA 5LU2A 4JC3A 3RDHA 4DHRA 3P1RA 2O98A 2WH0A 3SMMA 5HF3A 3P1QA 3SMOA 1O9CA 3UBWA 3CU8A 1YWTA 4WRQA 4DHMA 4DHOA 5LHOA 4DAUA 5BY9A 4N7YA 2C1JA 4E2EA 3IQVA 5LX2A 1A38A 1A4OA 4DHPA 1IB1A 5EWZA 3SMKA 2O8PA 3IQJA 5F74A 3SP5A 1YZ5A 1O9EA 3UZDA 2C23A 4FL5A 1O9FA 3UX0A 4GNTA 3AXYC 4F7RA 2C74A 3P1PA 4DNKA 5D3FA 4FR3A 2C1NA 2BTPA 4Y3BA 5LU1A 4N7GA 3UALA 3O8IA 3P1SA 3T0LA 2BQ0A 5EXAA 3LW1A 3NKXA 2BR9A 3SPRA 5D3EA 3M50A 4FJ3A 3P1OA 4DATA 2V7DA 4DHNA 3E6YA
chains in the Genus database with same CATH superfamily
4HKCA 5J31A 4ZDRA 3MHRA 4QLIA 3T0MA 1I5PA 4ZQ0A 4J6SA 5D2DA 1A37A 1QJAA 1O9DA 3P1NA 4BG6A 4DHSA 4DHQA 4Y5IA 2C63A 3I4RA 1QJBA 4IHLA 4DX0A 2B05A 4O46A 4ARXA 2NPMA 3SMLA 1CIYA 4ARYA 3EB7A 3CQGA 1W99A 2O02A 3M51A 4DHUA 5IQPA 5BTVA 5LVZA 3SMNA 4Y32A 4JDDA 3EFZA 4N84A 3U9XA 4DHTA 4IEAA 4D8MA 3IQUA 4QX2A 5LU2A 4JC3A 3RDHA 1S2XA 4DHRA 3P1RA 2O98A 2WH0A 3SMMA 5HF3A 3P1QA 4QX0A 3SMOA 1O9CA 3UBWA 3CU8A 1YWTA 4WRQA 4DHMA 4DHOA 5LHOA 4DAUA 1DLCA 5BY9A 4N7YA 2C1JA 4E2EA 3IQVA 5LX2A 4W8JA 1A38A 1A4OA 4DHPA 1IB1A 1URJA 5EWZA 3SMKA 2O8PA 3IQJA 5F74A 3SP5A 1YZ5A 1O9EA 4QX3A 2C23A 4FL5A 1O9FA 3UZDA 4QX1A 3UX0A 4GNTA 3AXYC 4F7RA 2C74A 3P1PA 4DNKA 3CQCA 1JI6A 3ZHEB 5D3FA 4MOAA 4FR3A 3X0UA 2BTPA 2C1NA 4Y3BA 5LU1A 4N7GA 3UALA 3O8IA 3P1SA 3T0LA 2BQ0A 5EXAA 3LW1A 3NKXA 2BR9A 3SPRA 5D3EA 3M50A 4FJ3A 2C9KA 3P1OA 4DATA 2V7DA 4DHNA 3E6YA
chains in the Genus database with same CATH topology
4HKCA 5J31A 4ZDRA 3MHRA 4QLIA 3T0MA 4ZQ0A 4J6SA 5D2DA 1A37A 1QJAA 1O9DA 3P1NA 4BG6A 4DHSA 4DHQA 4Y5IA 2C63A 1QJBA 4IHLA 4DX0A 2B05A 4O46A 2NPMA 3SMLA 2O02A 3M51A 5IQPA 4DHUA 5LVZA 5BTVA 3SMNA 4Y32A 4JDDA 3EFZA 4N84A 3U9XA 4DHTA 4IEAA 3IQUA 5LU2A 4JC3A 3RDHA 4DHRA 3P1RA 2O98A 2WH0A 3SMMA 5HF3A 3P1QA 3SMOA 1O9CA 3UBWA 3CU8A 1YWTA 4WRQA 4DHMA 4DHOA 5LHOA 4DAUA 5BY9A 4N7YA 2C1JA 4E2EA 3IQVA 5LX2A 1A38A 1A4OA 4DHPA 1IB1A 5EWZA 3SMKA 2O8PA 3IQJA 5F74A 3SP5A 1YZ5A 1O9EA 3UZDA 2C23A 4FL5A 1O9FA 3UX0A 4GNTA 3AXYC 4F7RA 2C74A 3P1PA 4DNKA 5D3FA 4FR3A 2C1NA 2BTPA 4Y3BA 5LU1A 4N7GA 3UALA 3O8IA 3P1SA 3T0LA 2BQ0A 5EXAA 3LW1A 3NKXA 2BR9A 3SPRA 5D3EA 3M50A 4FJ3A 3P1OA 4DATA 2V7DA 4DHNA 3E6YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HKC A;  5J31 A;  4ZDR A;  3MHR A;  4QLI A;  3T0M A;  4ZQ0 A;  4J6S A;  5D2D A;  1A37 A;  1QJA A;  1O9D A;  3P1N A;  4BG6 A;  4DHS A;  4DHQ A;  4Y5I A;  2C63 A;  1QJB A;  4IHL A;  4DX0 A;  2B05 A;  4O46 A;  2NPM A;  3SML A;  2O02 A;  3M51 A;  5IQP A;  4DHU A;  5LVZ A;  5BTV A;  3SMN A;  4Y32 A;  4JDD A;  3EFZ A;  4N84 A;  3U9X A;  4DHT A;  4IEA A;  3IQU A;  5LU2 A;  4JC3 A;  3RDH A;  4DHR A;  3P1R A;  2O98 A;  2WH0 A;  3SMM A;  5HF3 A;  3P1Q A;  3SMO A;  1O9C A;  3UBW A;  3CU8 A;  1YWT A;  4WRQ A;  4DHM A;  4DHO A;  5LHO A;  4DAU A;  5BY9 A;  4N7Y A;  2C1J A;  4E2E A;  3IQV A;  5LX2 A;  1A38 A;  1A4O A;  4DHP A;  1IB1 A;  5EWZ A;  3SMK A;  2O8P A;  3IQJ A;  5F74 A;  3SP5 A;  1YZ5 A;  1O9E A;  3UZD A;  2C23 A;  4FL5 A;  1O9F A;  3UX0 A;  4GNT A;  3AXY C;  4F7R A;  2C74 A;  3P1P A;  4DNK A;  5D3F A;  4FR3 A;  2C1N A;  2BTP A;  4Y3B A;  5LU1 A;  4N7G A;  3UAL A;  3O8I A;  3P1S A;  3T0L A;  2BQ0 A;  5EXA A;  3LW1 A;  3NKX A;  2BR9 A;  3SPR A;  5D3E A;  3M50 A;  4FJ3 A;  3P1O A;  4DAT A;  2V7D A;  4DHN A;  3E6Y A; 
#chains in the Genus database with same CATH topology
 4HKC A;  5J31 A;  4ZDR A;  3MHR A;  4QLI A;  3T0M A;  1I5P A;  4ZQ0 A;  4J6S A;  5D2D A;  1A37 A;  1QJA A;  1O9D A;  3P1N A;  4BG6 A;  4DHS A;  4DHQ A;  4Y5I A;  2C63 A;  3I4R A;  1QJB A;  4IHL A;  4DX0 A;  2B05 A;  4O46 A;  4ARX A;  2NPM A;  3SML A;  1CIY A;  4ARY A;  3EB7 A;  3CQG A;  1W99 A;  2O02 A;  3M51 A;  4DHU A;  5IQP A;  5BTV A;  5LVZ A;  3SMN A;  4Y32 A;  4JDD A;  3EFZ A;  4N84 A;  3U9X A;  4DHT A;  4IEA A;  4D8M A;  3IQU A;  4QX2 A;  5LU2 A;  4JC3 A;  3RDH A;  1S2X A;  4DHR A;  3P1R A;  2O98 A;  2WH0 A;  3SMM A;  5HF3 A;  3P1Q A;  4QX0 A;  3SMO A;  1O9C A;  3UBW A;  3CU8 A;  1YWT A;  4WRQ A;  4DHM A;  4DHO A;  5LHO A;  4DAU A;  1DLC A;  5BY9 A;  4N7Y A;  2C1J A;  4E2E A;  3IQV A;  5LX2 A;  4W8J A;  1A38 A;  1A4O A;  4DHP A;  1IB1 A;  1URJ A;  5EWZ A;  3SMK A;  2O8P A;  3IQJ A;  5F74 A;  3SP5 A;  1YZ5 A;  1O9E A;  4QX3 A;  2C23 A;  4FL5 A;  1O9F A;  3UZD A;  4QX1 A;  3UX0 A;  4GNT A;  3AXY C;  4F7R A;  2C74 A;  3P1P A;  4DNK A;  3CQC A;  1JI6 A;  3ZHE B;  5D3F A;  4MOA A;  4FR3 A;  3X0U A;  2BTP A;  2C1N A;  4Y3B A;  5LU1 A;  4N7G A;  3UAL A;  3O8I A;  3P1S A;  3T0L A;  2BQ0 A;  5EXA A;  3LW1 A;  3NKX A;  2BR9 A;  3SPR A;  5D3E A;  3M50 A;  4FJ3 A;  2C9K A;  3P1O A;  4DAT A;  2V7D A;  4DHN A;  3E6Y A; 
#chains in the Genus database with same CATH homology
 4HKC A;  5J31 A;  4ZDR A;  3MHR A;  4QLI A;  3T0M A;  4ZQ0 A;  4J6S A;  5D2D A;  1A37 A;  1QJA A;  1O9D A;  3P1N A;  4BG6 A;  4DHS A;  4DHQ A;  4Y5I A;  2C63 A;  1QJB A;  4IHL A;  4DX0 A;  2B05 A;  4O46 A;  2NPM A;  3SML A;  2O02 A;  3M51 A;  5IQP A;  4DHU A;  5LVZ A;  5BTV A;  3SMN A;  4Y32 A;  4JDD A;  3EFZ A;  4N84 A;  3U9X A;  4DHT A;  4IEA A;  3IQU A;  5LU2 A;  4JC3 A;  3RDH A;  4DHR A;  3P1R A;  2O98 A;  2WH0 A;  3SMM A;  5HF3 A;  3P1Q A;  3SMO A;  1O9C A;  3UBW A;  3CU8 A;  1YWT A;  4WRQ A;  4DHM A;  4DHO A;  5LHO A;  4DAU A;  5BY9 A;  4N7Y A;  2C1J A;  4E2E A;  3IQV A;  5LX2 A;  1A38 A;  1A4O A;  4DHP A;  1IB1 A;  5EWZ A;  3SMK A;  2O8P A;  3IQJ A;  5F74 A;  3SP5 A;  1YZ5 A;  1O9E A;  3UZD A;  2C23 A;  4FL5 A;  1O9F A;  3UX0 A;  4GNT A;  3AXY C;  4F7R A;  2C74 A;  3P1P A;  4DNK A;  5D3F A;  4FR3 A;  2C1N A;  2BTP A;  4Y3B A;  5LU1 A;  4N7G A;  3UAL A;  3O8I A;  3P1S A;  3T0L A;  2BQ0 A;  5EXA A;  3LW1 A;  3NKX A;  2BR9 A;  3SPR A;  5D3E A;  3M50 A;  4FJ3 A;  3P1O A;  4DAT A;  2V7D A;  4DHN A;  3E6Y A; 
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