3CC4W

Co-crystal structure of anisomycin bound to the 50s ribosomal subunit
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ribosome
publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule keywords 50S ribosomal protein L2P
total genus 46
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3cc4W02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 3cc4W01
4U67W 4WFAW 1VQ7W 3CCMW 3I56W 5GAEa 2ZJPW 1YIJW 1K8AX 4WFNW 1W2BV 2ZJRW 1YJNW 1S72W 3CXCV 1QVFV 1VQOW 1YJWW 5DM7W 1KQSV 5GAHa 1VQ8W 3CC2W 1YHQW 1Q82X 4WFBW 2QEXW 3G71W 3CCUW 4WCEW 1VQ4W 1VQKW 3G6EW 1M1KX 3PIOW 4WF9W 3CCLW 1Q81X 1YITW 4IOCW 2ZJQW 1Q86X 3CCJW 3G4SW 3CCRW 1VQ5W 4IOAW 2OTLW 1VQNW 3CMAW 1Q7YX 1KD1X 5JVGW 3DLLW 5GADa 3CD6W 1QVGV 1VQMW 1VQLW 3CC4W 3CMEW 1N8RX 1VQPW 1YJ9W 3CC7W 3J7ZZ 1YI2W 1VQ6W 3CCQW 1KC8X 5GAGa 4IO9W 1NJIX 5JVHW 5HL7W 1VQ9W 3CCEW 1BXYA 2QA4W 5DM6W 3I55W 3CCVW 2OTJW 1K73X 3OW2V 3CF5W 4UY8Z 3PIPW 1JJ2V 3CCSW 3CPWV 1K9MX 1M90X
chains in the Genus database with same CATH superfamily
4U67W 4YJMA 4WFAW 1VQ7W 1R6OC 5GW7A 3CCMW 3I56W 5GAEa 5M1AA 2ZJPW 1YIJW 1K8AX 4WFNW 1W2BV 1MBXC 2ZJRW 1YJNW 3W7SA 4BL3A 3GW1A 1S72W 3CXCV 3W7XA 1QVFV 3O2OA 2WA8A 1VQOW 1YJWW 5M19A 5DM7W 1KQSV 1MWTA 1RQVA 5GAHa 1VQ8W 3CC2W 1RQSA 1YHQW 3G19A 3W7TA 1Q82X 4WFBW 2QEXW 3G71W 1CTFA 1MWUA 3CCUW 4WCEW 1VQ4W 1VQKW 3G6EW 1M1KX 2WA9A 3PIOW 4WF9W 3CCLW 3DNJA 1Q81X 1YITW 3ZFZA 4IOCW 1MWRA 2ZJQW 1Q86X 3CCJW 3G4SW 3CCRW 1VQ5W 4IOAW 2OTLW 1VQNW 3CMAW 1VQQA 1Q7YX 1KD1X 5JVGW 3ZG0A 1RQUA 1DD3A 3DLLW 5CA3A 5GADa 3CD6W 1QVGV 1VQMW 1VQLW 3CC4W 3CMEW 1N8RX 3GQ0A 3G1BA 1VQPW 1YJ9W 3CC7W 3J7ZZ 1YI2W 4CJNA 1DD4A 1VQ6W 3W7UA 3CCQW 3O2BA 4YKAA 1KC8X 5GAGa 4IO9W 1NJIX 1MBVB 4CPKA 3O1FB 5JVHW 3W7WA 5HL7W 1VQ9W 1MBUC 4C1NA 1R6QC 4BL2A 3CCEW 1BXYA 2QA4W 3GQ1A 5DM6W 3I55W 3CCVW 2OTJW 2W9RA 1LZWA 1K73X 3OW2V 3CF5W 4UY8Z 3ZG5A 1MG9A 3O1FA 3O2HA 3PIPW 1JJ2V 3D3IA 3CCSW 4DKIA 1MWSA 3CPWV 3G3PA 4YJXA 5M18A 1K9MX 1M90X
chains in the Genus database with same CATH topology
4U67W 4WFAW 1VQ7W 3CCMW 3I56W 5GAEa 2ZJPW 1YIJW 1K8AX 4WFNW 1W2BV 2ZJRW 1YJNW 1S72W 3CXCV 1QVFV 1VQOW 1YJWW 5DM7W 1KQSV 5GAHa 1VQ8W 3CC2W 1YHQW 1Q82X 4WFBW 2QEXW 3G71W 3CCUW 4WCEW 1VQ4W 1VQKW 3G6EW 1M1KX 3PIOW 4WF9W 3CCLW 1Q81X 1YITW 4IOCW 2ZJQW 1Q86X 3CCJW 3G4SW 3CCRW 1VQ5W 4IOAW 2OTLW 1VQNW 3CMAW 1Q7YX 1KD1X 5JVGW 3DLLW 5GADa 3CD6W 1QVGV 1VQMW 1VQLW 3CC4W 3CMEW 1N8RX 1VQPW 1YJ9W 3CC7W 3J7ZZ 1YI2W 1VQ6W 3CCQW 1KC8X 5GAGa 4IO9W 1NJIX 5JVHW 5HL7W 1VQ9W 4C1NA 3CCEW 1BXYA 2QA4W 5DM6W 3I55W 3CCVW 2OTJW 1K73X 3OW2V 3CF5W 4UY8Z 3PIPW 1JJ2V 3CCSW 3CPWV 1K9MX 1M90X
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4U67 W;  4WFA W;  1VQ7 W;  3CCM W;  3I56 W;  5GAE a;  2ZJP W;  1YIJ W;  1K8A X;  4WFN W;  1W2B V;  2ZJR W;  1YJN W;  1S72 W;  3CXC V;  1QVF V;  1VQO W;  1YJW W;  5DM7 W;  1KQS V;  5GAH a;  1VQ8 W;  3CC2 W;  1YHQ W;  1Q82 X;  4WFB W;  2QEX W;  3G71 W;  3CCU W;  4WCE W;  1VQ4 W;  1VQK W;  3G6E W;  1M1K X;  3PIO W;  4WF9 W;  3CCL W;  1Q81 X;  1YIT W;  4IOC W;  2ZJQ W;  1Q86 X;  3CCJ W;  3G4S W;  3CCR W;  1VQ5 W;  4IOA W;  2OTL W;  1VQN W;  3CMA W;  1Q7Y X;  1KD1 X;  5JVG W;  3DLL W;  5GAD a;  3CD6 W;  1QVG V;  1VQM W;  1VQL W;  3CC4 W;  3CME W;  1N8R X;  1VQP W;  1YJ9 W;  3CC7 W;  3J7Z Z;  1YI2 W;  1VQ6 W;  3CCQ W;  1KC8 X;  5GAG a;  4IO9 W;  1NJI X;  5JVH W;  5HL7 W;  1VQ9 W;  3CCE W;  1BXY A;  2QA4 W;  5DM6 W;  3I55 W;  3CCV W;  2OTJ W;  1K73 X;  3OW2 V;  3CF5 W;  4UY8 Z;  3PIP W;  1JJ2 V;  3CCS W;  3CPW V;  1K9M X;  1M90 X; 
#chains in the Genus database with same CATH topology
 4U67 W;  4YJM A;  4WFA W;  1VQ7 W;  1R6O C;  5GW7 A;  3CCM W;  3I56 W;  5GAE a;  5M1A A;  2ZJP W;  1YIJ W;  1K8A X;  4WFN W;  1W2B V;  1MBX C;  2ZJR W;  1YJN W;  3W7S A;  4BL3 A;  3GW1 A;  1S72 W;  3CXC V;  3W7X A;  1QVF V;  3O2O A;  2WA8 A;  1VQO W;  1YJW W;  5M19 A;  5DM7 W;  1KQS V;  1MWT A;  1RQV A;  5GAH a;  1VQ8 W;  3CC2 W;  1RQS A;  1YHQ W;  3G19 A;  3W7T A;  1Q82 X;  4WFB W;  2QEX W;  3G71 W;  1CTF A;  1MWU A;  3CCU W;  4WCE W;  1VQ4 W;  1VQK W;  3G6E W;  1M1K X;  2WA9 A;  3PIO W;  4WF9 W;  3CCL W;  3DNJ A;  1Q81 X;  1YIT W;  3ZFZ A;  4IOC W;  1MWR A;  2ZJQ W;  1Q86 X;  3CCJ W;  3G4S W;  3CCR W;  1VQ5 W;  4IOA W;  2OTL W;  1VQN W;  3CMA W;  1VQQ A;  1Q7Y X;  1KD1 X;  5JVG W;  3ZG0 A;  1RQU A;  1DD3 A;  3DLL W;  5CA3 A;  5GAD a;  3CD6 W;  1QVG V;  1VQM W;  1VQL W;  3CC4 W;  3CME W;  1N8R X;  3GQ0 A;  3G1B A;  1VQP W;  1YJ9 W;  3CC7 W;  3J7Z Z;  1YI2 W;  4CJN A;  1DD4 A;  1VQ6 W;  3W7U A;  3CCQ W;  3O2B A;  4YKA A;  1KC8 X;  5GAG a;  4IO9 W;  1NJI X;  1MBV B;  4CPK A;  3O1F B;  5JVH W;  3W7W A;  5HL7 W;  1VQ9 W;  1MBU C;  4C1N A;  1R6Q C;  4BL2 A;  3CCE W;  1BXY A;  2QA4 W;  3GQ1 A;  5DM6 W;  3I55 W;  3CCV W;  2OTJ W;  2W9R A;  1LZW A;  1K73 X;  3OW2 V;  3CF5 W;  4UY8 Z;  3ZG5 A;  1MG9 A;  3O1F A;  3O2H A;  3PIP W;  1JJ2 V;  3D3I A;  3CCS W;  4DKI A;  1MWS A;  3CPW V;  3G3P A;  4YJX A;  5M18 A;  1K9M X;  1M90 X; 
#chains in the Genus database with same CATH homology
 4U67 W;  4WFA W;  1VQ7 W;  3CCM W;  3I56 W;  5GAE a;  2ZJP W;  1YIJ W;  1K8A X;  4WFN W;  1W2B V;  2ZJR W;  1YJN W;  1S72 W;  3CXC V;  1QVF V;  1VQO W;  1YJW W;  5DM7 W;  1KQS V;  5GAH a;  1VQ8 W;  3CC2 W;  1YHQ W;  1Q82 X;  4WFB W;  2QEX W;  3G71 W;  3CCU W;  4WCE W;  1VQ4 W;  1VQK W;  3G6E W;  1M1K X;  3PIO W;  4WF9 W;  3CCL W;  1Q81 X;  1YIT W;  4IOC W;  2ZJQ W;  1Q86 X;  3CCJ W;  3G4S W;  3CCR W;  1VQ5 W;  4IOA W;  2OTL W;  1VQN W;  3CMA W;  1Q7Y X;  1KD1 X;  5JVG W;  3DLL W;  5GAD a;  3CD6 W;  1QVG V;  1VQM W;  1VQL W;  3CC4 W;  3CME W;  1N8R X;  1VQP W;  1YJ9 W;  3CC7 W;  3J7Z Z;  1YI2 W;  1VQ6 W;  3CCQ W;  1KC8 X;  5GAG a;  4IO9 W;  1NJI X;  5JVH W;  5HL7 W;  1VQ9 W;  4C1N A;  3CCE W;  1BXY A;  2QA4 W;  5DM6 W;  3I55 W;  3CCV W;  2OTJ W;  1K73 X;  3OW2 V;  3CF5 W;  4UY8 Z;  3PIP W;  1JJ2 V;  3CCS W;  3CPW V;  1K9M X;  1M90 X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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