3CCJW

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation c2534u
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 43
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3ccjW02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 3ccjW01
4IOAW 4U67W 3CXCV 1QVGV 2ZJQW 3CCQW 4WCEW 3CCUW 3CC2W 1Q81X 1VQKW 1YJ9W 3CPWV 4WFBW 1YHQW 1VQNW 4WF9W 1VQMW 4WFAW 1VQ5W 5JVHW 1M90X 3I56W 1QVFV 3CCLW 5GAHa 1JJ2V 1VQ8W 3CC4W 3G6EW 1Q7YX 1BXYA 1KQSV 1KC8X 3CF5W 3CCMW 1W2BV 5HL7W 1YJWW 2ZJPW 4WFNW 1Q86X 1K8AX 1M1KX 5GAGa 3J7ZZ 5DM6W 1K9MX 1VQLW 1VQOW 1Q82X 3CC7W 5GADa 3CCSW 3CMAW 2OTLW 3G4SW 1YI2W 3CCEW 1YIJW 3PIPW 1VQPW 1KD1X 3CMEW 1VQ9W 1YITW 1VQ4W 3CCJW 4IOCW 5GAEa 3CCRW 1YJNW 2QEXW 1NJIX 3G71W 1S72W 1VQ6W 2OTJW 3DLLW 3CCVW 3OW2V 3CD6W 3I55W 4UY8Z 1K73X 2ZJRW 3PIOW 2QA4W 1N8RX 4IO9W 1VQ7W 5JVGW 5DM7W
chains in the Genus database with same CATH superfamily
4IOAW 3GQ1A 1MWRA 4U67W 3W7XA 3CXCV 1QVGV 2ZJQW 3CCQW 4WCEW 2WA9A 3CCUW 3CC2W 3GW1A 1Q81X 3GQ0A 1VQKW 1YJ9W 3CPWV 4WFBW 1YHQW 3G1BA 3D3IA 1VQNW 4WF9W 1VQMW 4WFAW 1VQ5W 2W9RA 5JVHW 4BL2A 1M90X 1VQQA 3I56W 4CJNA 1QVFV 3CCLW 5GAHa 1R6OC 1JJ2V 1VQ8W 3CC4W 3O2BA 3G6EW 1Q7YX 1BXYA 1MBUC 1KQSV 3ZG0A 1KC8X 3CF5W 3W7SA 3CCMW 3W7TA 5DM7W 1W2BV 5HL7W 1YJWW 2ZJPW 1RQSA 3W7UA 4WFNW 1MBXC 1Q86X 1K8AX 1M1KX 1MBVB 5GAGa 3J7ZZ 3G3PA 1RQUA 1LZWA 1DD4A 1MWSA 5M19A 3W7WA 5DM6W 1K9MX 1VQLW 1VQOW 1Q82X 4YJMA 3CC7W 4YKAA 5GADa 3CCSW 3CMAW 2OTLW 3G4SW 1YI2W 5M18A 3G19A 3CCEW 1YIJW 5M1AA 3PIPW 1MG9A 1VQPW 4YJXA 1KD1X 1DD3A 3CMEW 3O1FB 1VQ9W 1YITW 2WA8A 1VQ4W 5GW7A 3CCJW 1MWUA 3O1FA 4C1NA 4IOCW 5GAEa 3CCRW 1YJNW 2QEXW 1NJIX 3G71W 1S72W 1RQVA 3DNJA 1VQ6W 2OTJW 3DLLW 1R6QC 3CCVW 3OW2V 3CD6W 3O2OA 4BL3A 3I55W 1CTFA 1K73X 2ZJRW 3PIOW 4UY8Z 3ZFZA 3ZG5A 2QA4W 1N8RX 4DKIA 4IO9W 5CA3A 1VQ7W 1MWTA 5JVGW 4CPKA 3O2HA
chains in the Genus database with same CATH topology
4IOAW 4U67W 3CXCV 1QVGV 2ZJQW 3CCQW 4WCEW 3CCUW 3CC2W 1Q81X 1VQKW 1YJ9W 3CPWV 4WFBW 1YHQW 1VQNW 4WF9W 1VQMW 4WFAW 1VQ5W 5JVHW 1M90X 3I56W 1QVFV 3CCLW 5GAHa 1JJ2V 1VQ8W 3CC4W 3G6EW 1Q7YX 1BXYA 1KQSV 1KC8X 3CF5W 3CCMW 1W2BV 5HL7W 1YJWW 2ZJPW 4WFNW 1Q86X 1K8AX 1M1KX 5GAGa 3J7ZZ 5DM6W 1K9MX 1VQLW 1VQOW 1Q82X 3CC7W 5GADa 3CCSW 3CMAW 2OTLW 3G4SW 1YI2W 3CCEW 1YIJW 3PIPW 1VQPW 1KD1X 3CMEW 1VQ9W 1YITW 1VQ4W 3CCJW 4C1NA 4IOCW 5GAEa 3CCRW 1YJNW 2QEXW 1NJIX 3G71W 1S72W 1VQ6W 2OTJW 3DLLW 3CCVW 3OW2V 3CD6W 3I55W 4UY8Z 1K73X 2ZJRW 3PIOW 2QA4W 1N8RX 4IO9W 1VQ7W 5JVGW 5DM7W
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IOA W;  4U67 W;  3CXC V;  1QVG V;  2ZJQ W;  3CCQ W;  4WCE W;  3CCU W;  3CC2 W;  1Q81 X;  1VQK W;  1YJ9 W;  3CPW V;  4WFB W;  1YHQ W;  1VQN W;  4WF9 W;  1VQM W;  4WFA W;  1VQ5 W;  5JVH W;  1M90 X;  3I56 W;  1QVF V;  3CCL W;  5GAH a;  1JJ2 V;  1VQ8 W;  3CC4 W;  3G6E W;  1Q7Y X;  1BXY A;  1KQS V;  1KC8 X;  3CF5 W;  3CCM W;  1W2B V;  5HL7 W;  1YJW W;  2ZJP W;  4WFN W;  1Q86 X;  1K8A X;  1M1K X;  5GAG a;  3J7Z Z;  5DM6 W;  1K9M X;  1VQL W;  1VQO W;  1Q82 X;  3CC7 W;  5GAD a;  3CCS W;  3CMA W;  2OTL W;  3G4S W;  1YI2 W;  3CCE W;  1YIJ W;  3PIP W;  1VQP W;  1KD1 X;  3CME W;  1VQ9 W;  1YIT W;  1VQ4 W;  3CCJ W;  4IOC W;  5GAE a;  3CCR W;  1YJN W;  2QEX W;  1NJI X;  3G71 W;  1S72 W;  1VQ6 W;  2OTJ W;  3DLL W;  3CCV W;  3OW2 V;  3CD6 W;  3I55 W;  4UY8 Z;  1K73 X;  2ZJR W;  3PIO W;  2QA4 W;  1N8R X;  4IO9 W;  1VQ7 W;  5JVG W;  5DM7 W; 
#chains in the Genus database with same CATH topology
 4IOA W;  3GQ1 A;  1MWR A;  4U67 W;  3W7X A;  3CXC V;  1QVG V;  2ZJQ W;  3CCQ W;  4WCE W;  2WA9 A;  3CCU W;  3CC2 W;  3GW1 A;  1Q81 X;  3GQ0 A;  1VQK W;  1YJ9 W;  3CPW V;  4WFB W;  1YHQ W;  3G1B A;  3D3I A;  1VQN W;  4WF9 W;  1VQM W;  4WFA W;  1VQ5 W;  2W9R A;  5JVH W;  4BL2 A;  1M90 X;  1VQQ A;  3I56 W;  4CJN A;  1QVF V;  3CCL W;  5GAH a;  1R6O C;  1JJ2 V;  1VQ8 W;  3CC4 W;  3O2B A;  3G6E W;  1Q7Y X;  1BXY A;  1MBU C;  1KQS V;  3ZG0 A;  1KC8 X;  3CF5 W;  3W7S A;  3CCM W;  3W7T A;  5DM7 W;  1W2B V;  5HL7 W;  1YJW W;  2ZJP W;  1RQS A;  3W7U A;  4WFN W;  1MBX C;  1Q86 X;  1K8A X;  1M1K X;  1MBV B;  5GAG a;  3J7Z Z;  3G3P A;  1RQU A;  1LZW A;  1DD4 A;  1MWS A;  5M19 A;  3W7W A;  5DM6 W;  1K9M X;  1VQL W;  1VQO W;  1Q82 X;  4YJM A;  3CC7 W;  4YKA A;  5GAD a;  3CCS W;  3CMA W;  2OTL W;  3G4S W;  1YI2 W;  5M18 A;  3G19 A;  3CCE W;  1YIJ W;  5M1A A;  3PIP W;  1MG9 A;  1VQP W;  4YJX A;  1KD1 X;  1DD3 A;  3CME W;  3O1F B;  1VQ9 W;  1YIT W;  2WA8 A;  1VQ4 W;  5GW7 A;  3CCJ W;  1MWU A;  3O1F A;  4C1N A;  4IOC W;  5GAE a;  3CCR W;  1YJN W;  2QEX W;  1NJI X;  3G71 W;  1S72 W;  1RQV A;  3DNJ A;  1VQ6 W;  2OTJ W;  3DLL W;  1R6Q C;  3CCV W;  3OW2 V;  3CD6 W;  3O2O A;  4BL3 A;  3I55 W;  1CTF A;  1K73 X;  2ZJR W;  3PIO W;  4UY8 Z;  3ZFZ A;  3ZG5 A;  2QA4 W;  1N8R X;  4DKI A;  4IO9 W;  5CA3 A;  1VQ7 W;  1MWT A;  5JVG W;  4CPK A;  3O2H A; 
#chains in the Genus database with same CATH homology
 4IOA W;  4U67 W;  3CXC V;  1QVG V;  2ZJQ W;  3CCQ W;  4WCE W;  3CCU W;  3CC2 W;  1Q81 X;  1VQK W;  1YJ9 W;  3CPW V;  4WFB W;  1YHQ W;  1VQN W;  4WF9 W;  1VQM W;  4WFA W;  1VQ5 W;  5JVH W;  1M90 X;  3I56 W;  1QVF V;  3CCL W;  5GAH a;  1JJ2 V;  1VQ8 W;  3CC4 W;  3G6E W;  1Q7Y X;  1BXY A;  1KQS V;  1KC8 X;  3CF5 W;  3CCM W;  1W2B V;  5HL7 W;  1YJW W;  2ZJP W;  4WFN W;  1Q86 X;  1K8A X;  1M1K X;  5GAG a;  3J7Z Z;  5DM6 W;  1K9M X;  1VQL W;  1VQO W;  1Q82 X;  3CC7 W;  5GAD a;  3CCS W;  3CMA W;  2OTL W;  3G4S W;  1YI2 W;  3CCE W;  1YIJ W;  3PIP W;  1VQP W;  1KD1 X;  3CME W;  1VQ9 W;  1YIT W;  1VQ4 W;  3CCJ W;  4C1N A;  4IOC W;  5GAE a;  3CCR W;  1YJN W;  2QEX W;  1NJI X;  3G71 W;  1S72 W;  1VQ6 W;  2OTJ W;  3DLL W;  3CCV W;  3OW2 V;  3CD6 W;  3I55 W;  4UY8 Z;  1K73 X;  2ZJR W;  3PIO W;  2QA4 W;  1N8R X;  4IO9 W;  1VQ7 W;  5JVG W;  5DM7 W; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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