3CCLW

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535c. density for anisomycin is visible but not included in model.
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ribosome
publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule keywords 50S ribosomal protein L2P
total genus 49
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3cclW02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 3cclW01
3CXCV 3J7ZZ 1K9MX 3G71W 3CC2W 3CCSW 1VQ6W 3CD6W 1N8RX 1YIJW 3PIOW 1VQPW 4IOAW 1VQ4W 4U67W 1YI2W 4WCEW 1YITW 1S72W 1W2BV 1VQ8W 4WF9W 4UY8Z 3CCRW 3CCLW 1M90X 3G6EW 5GADa 3I55W 1KD1X 3PIPW 3OW2V 3CC4W 1Q86X 1K73X 2QEXW 1VQMW 2ZJPW 1Q82X 1KQSV 1VQ5W 1QVGV 3CCEW 3CPWV 3CCVW 2OTJW 5DM7W 1NJIX 3CMEW 1YJWW 1K8AX 5DM6W 3CCQW 1VQKW 1BXYA 1QVFV 4IO9W 1YJNW 5JVHW 5GAGa 2ZJRW 2OTLW 5HL7W 3DLLW 2ZJQW 1VQNW 5JVGW 4WFNW 1JJ2V 1Q81X 1Q7YX 5GAHa 1YJ9W 3CCMW 5GAEa 3CF5W 3I56W 4WFAW 3CCJW 4IOCW 3CC7W 3G4SW 1KC8X 4WFBW 3CCUW 1VQLW 1VQ9W 2QA4W 1VQ7W 1VQOW 3CMAW 1YHQW 1M1KX
chains in the Genus database with same CATH superfamily
3CXCV 4YJXA 3J7ZZ 1K9MX 3G71W 3CC2W 3CCSW 1VQ6W 3CD6W 1N8RX 1YIJW 3PIOW 1VQPW 1VQQA 4IOAW 2W9RA 1CTFA 4YKAA 1VQ4W 4U67W 1MWSA 3O2BA 1YI2W 4WCEW 1YITW 4YJMA 1S72W 5M19A 1W2BV 1VQ8W 4WF9W 4UY8Z 4C1NA 3CCRW 3CCLW 1M90X 1MBVB 4DKIA 3G6EW 3D3IA 5GADa 1DD3A 3O1FB 3W7TA 3I55W 1KD1X 1MBXC 3O2HA 1MBUC 3W7SA 4CJNA 3PIPW 3OW2V 3W7XA 3CC4W 1Q86X 3DNJA 3GQ0A 3O1FA 3ZG0A 1K73X 2QEXW 1VQMW 2ZJPW 1Q82X 1KQSV 1VQ5W 1DD4A 1QVGV 3CCEW 1LZWA 5M18A 3CPWV 3ZG5A 3CCVW 2OTJW 1RQUA 5DM7W 1NJIX 2WA9A 3CMEW 1YJWW 1K8AX 1MWTA 5DM6W 5M1AA 3CCQW 1VQKW 1BXYA 1QVFV 4IO9W 1YJNW 5JVHW 5GW7A 5GAGa 2ZJRW 3G1BA 3GW1A 2OTLW 2WA8A 1MG9A 1MWRA 5HL7W 3DLLW 2ZJQW 1R6QC 1VQNW 3W7UA 3GQ1A 5JVGW 4WFNW 1JJ2V 1Q81X 1R6OC 3ZFZA 3W7WA 1RQSA 1Q7YX 3O2OA 5GAHa 3G19A 5CA3A 1YJ9W 3CCMW 4CPKA 5GAEa 3CF5W 3I56W 4WFAW 3G3PA 3CCJW 4IOCW 3CC7W 3G4SW 1KC8X 4WFBW 3CCUW 1VQLW 1VQ9W 2QA4W 1VQ7W 1VQOW 4BL2A 4BL3A 3CMAW 1YHQW 1RQVA 1MWUA 1M1KX
chains in the Genus database with same CATH topology
3CXCV 3J7ZZ 1K9MX 3G71W 3CC2W 3CCSW 1VQ6W 3CD6W 1N8RX 1YIJW 3PIOW 1VQPW 4IOAW 1VQ4W 4U67W 1YI2W 4WCEW 1YITW 1S72W 1W2BV 1VQ8W 4WF9W 4UY8Z 4C1NA 3CCRW 3CCLW 1M90X 3G6EW 5GADa 3I55W 1KD1X 3PIPW 3OW2V 3CC4W 1Q86X 1K73X 2QEXW 1VQMW 2ZJPW 1Q82X 1KQSV 1VQ5W 1QVGV 3CCEW 3CPWV 3CCVW 2OTJW 5DM7W 1NJIX 3CMEW 1YJWW 1K8AX 5DM6W 3CCQW 1VQKW 1BXYA 1QVFV 4IO9W 1YJNW 5JVHW 5GAGa 2ZJRW 2OTLW 5HL7W 3DLLW 2ZJQW 1VQNW 5JVGW 4WFNW 1JJ2V 1Q81X 1Q7YX 5GAHa 1YJ9W 3CCMW 5GAEa 3CF5W 3I56W 4WFAW 3CCJW 4IOCW 3CC7W 3G4SW 1KC8X 4WFBW 3CCUW 1VQLW 1VQ9W 2QA4W 1VQ7W 1VQOW 3CMAW 1YHQW 1M1KX
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CXC V;  3J7Z Z;  1K9M X;  3G71 W;  3CC2 W;  3CCS W;  1VQ6 W;  3CD6 W;  1N8R X;  1YIJ W;  3PIO W;  1VQP W;  4IOA W;  1VQ4 W;  4U67 W;  1YI2 W;  4WCE W;  1YIT W;  1S72 W;  1W2B V;  1VQ8 W;  4WF9 W;  4UY8 Z;  3CCR W;  3CCL W;  1M90 X;  3G6E W;  5GAD a;  3I55 W;  1KD1 X;  3PIP W;  3OW2 V;  3CC4 W;  1Q86 X;  1K73 X;  2QEX W;  1VQM W;  2ZJP W;  1Q82 X;  1KQS V;  1VQ5 W;  1QVG V;  3CCE W;  3CPW V;  3CCV W;  2OTJ W;  5DM7 W;  1NJI X;  3CME W;  1YJW W;  1K8A X;  5DM6 W;  3CCQ W;  1VQK W;  1BXY A;  1QVF V;  4IO9 W;  1YJN W;  5JVH W;  5GAG a;  2ZJR W;  2OTL W;  5HL7 W;  3DLL W;  2ZJQ W;  1VQN W;  5JVG W;  4WFN W;  1JJ2 V;  1Q81 X;  1Q7Y X;  5GAH a;  1YJ9 W;  3CCM W;  5GAE a;  3CF5 W;  3I56 W;  4WFA W;  3CCJ W;  4IOC W;  3CC7 W;  3G4S W;  1KC8 X;  4WFB W;  3CCU W;  1VQL W;  1VQ9 W;  2QA4 W;  1VQ7 W;  1VQO W;  3CMA W;  1YHQ W;  1M1K X; 
#chains in the Genus database with same CATH topology
 3CXC V;  4YJX A;  3J7Z Z;  1K9M X;  3G71 W;  3CC2 W;  3CCS W;  1VQ6 W;  3CD6 W;  1N8R X;  1YIJ W;  3PIO W;  1VQP W;  1VQQ A;  4IOA W;  2W9R A;  1CTF A;  4YKA A;  1VQ4 W;  4U67 W;  1MWS A;  3O2B A;  1YI2 W;  4WCE W;  1YIT W;  4YJM A;  1S72 W;  5M19 A;  1W2B V;  1VQ8 W;  4WF9 W;  4UY8 Z;  4C1N A;  3CCR W;  3CCL W;  1M90 X;  1MBV B;  4DKI A;  3G6E W;  3D3I A;  5GAD a;  1DD3 A;  3O1F B;  3W7T A;  3I55 W;  1KD1 X;  1MBX C;  3O2H A;  1MBU C;  3W7S A;  4CJN A;  3PIP W;  3OW2 V;  3W7X A;  3CC4 W;  1Q86 X;  3DNJ A;  3GQ0 A;  3O1F A;  3ZG0 A;  1K73 X;  2QEX W;  1VQM W;  2ZJP W;  1Q82 X;  1KQS V;  1VQ5 W;  1DD4 A;  1QVG V;  3CCE W;  1LZW A;  5M18 A;  3CPW V;  3ZG5 A;  3CCV W;  2OTJ W;  1RQU A;  5DM7 W;  1NJI X;  2WA9 A;  3CME W;  1YJW W;  1K8A X;  1MWT A;  5DM6 W;  5M1A A;  3CCQ W;  1VQK W;  1BXY A;  1QVF V;  4IO9 W;  1YJN W;  5JVH W;  5GW7 A;  5GAG a;  2ZJR W;  3G1B A;  3GW1 A;  2OTL W;  2WA8 A;  1MG9 A;  1MWR A;  5HL7 W;  3DLL W;  2ZJQ W;  1R6Q C;  1VQN W;  3W7U A;  3GQ1 A;  5JVG W;  4WFN W;  1JJ2 V;  1Q81 X;  1R6O C;  3ZFZ A;  3W7W A;  1RQS A;  1Q7Y X;  3O2O A;  5GAH a;  3G19 A;  5CA3 A;  1YJ9 W;  3CCM W;  4CPK A;  5GAE a;  3CF5 W;  3I56 W;  4WFA W;  3G3P A;  3CCJ W;  4IOC W;  3CC7 W;  3G4S W;  1KC8 X;  4WFB W;  3CCU W;  1VQL W;  1VQ9 W;  2QA4 W;  1VQ7 W;  1VQO W;  4BL2 A;  4BL3 A;  3CMA W;  1YHQ W;  1RQV A;  1MWU A;  1M1K X; 
#chains in the Genus database with same CATH homology
 3CXC V;  3J7Z Z;  1K9M X;  3G71 W;  3CC2 W;  3CCS W;  1VQ6 W;  3CD6 W;  1N8R X;  1YIJ W;  3PIO W;  1VQP W;  4IOA W;  1VQ4 W;  4U67 W;  1YI2 W;  4WCE W;  1YIT W;  1S72 W;  1W2B V;  1VQ8 W;  4WF9 W;  4UY8 Z;  4C1N A;  3CCR W;  3CCL W;  1M90 X;  3G6E W;  5GAD a;  3I55 W;  1KD1 X;  3PIP W;  3OW2 V;  3CC4 W;  1Q86 X;  1K73 X;  2QEX W;  1VQM W;  2ZJP W;  1Q82 X;  1KQS V;  1VQ5 W;  1QVG V;  3CCE W;  3CPW V;  3CCV W;  2OTJ W;  5DM7 W;  1NJI X;  3CME W;  1YJW W;  1K8A X;  5DM6 W;  3CCQ W;  1VQK W;  1BXY A;  1QVF V;  4IO9 W;  1YJN W;  5JVH W;  5GAG a;  2ZJR W;  2OTL W;  5HL7 W;  3DLL W;  2ZJQ W;  1VQN W;  5JVG W;  4WFN W;  1JJ2 V;  1Q81 X;  1Q7Y X;  5GAH a;  1YJ9 W;  3CCM W;  5GAE a;  3CF5 W;  3I56 W;  4WFA W;  3CCJ W;  4IOC W;  3CC7 W;  3G4S W;  1KC8 X;  4WFB W;  3CCU W;  1VQL W;  1VQ9 W;  2QA4 W;  1VQ7 W;  1VQO W;  3CMA W;  1YHQ W;  1M1K X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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