3CCLW

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535c. density for anisomycin is visible but not included in model.
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 49
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3cclW02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 3cclW01
1KC8X 1VQ4W 3CMEW 3I55W 1YIJW 1VQ8W 5HL7W 3CCSW 1QVGV 3J7ZZ 3CCVW 5DM7W 3CC4W 1YITW 1Q81X 1W2BV 1JJ2V 1S72W 1KD1X 3PIPW 5GADa 4WFAW 1VQ5W 3PIOW 3G4SW 1VQNW 4WF9W 3G71W 5GAGa 2QEXW 5JVGW 1K73X 1N8RX 3CD6W 3CXCV 1M90X 1VQLW 5GAEa 5JVHW 1KQSV 3CCJW 2ZJRW 4WFNW 1K8AX 3OW2V 1VQ7W 1M1KX 1VQOW 3I56W 5DM6W 2OTLW 1VQKW 1K9MX 1VQ6W 1VQ9W 1VQPW 4UY8Z 3CC2W 4IOCW 4WFBW 2ZJQW 3CC7W 1QVFV 1YJ9W 1YJNW 4U67W 1YJWW 3CCQW 2QA4W 3CPWV 3CCRW 1Q86X 1Q82X 5GAHa 4WCEW 2ZJPW 3CCUW 4IO9W 1VQMW 1NJIX 3CCEW 1Q7YX 3G6EW 3CCMW 3CMAW 3DLLW 3CF5W 1YHQW 1YI2W 3CCLW 1BXYA 2OTJW 4IOAW
chains in the Genus database with same CATH superfamily
1KC8X 1VQ4W 3CMEW 1R6OC 1R6QC 3I55W 3W7WA 1YIJW 1VQ8W 5HL7W 5GW7A 3CCSW 1QVGV 3J7ZZ 3CCVW 5DM7W 3CC4W 1YITW 1Q81X 1W2BV 3W7TA 1JJ2V 1S72W 3ZG0A 3O1FA 1RQVA 1MG9A 1KD1X 3PIPW 5GADa 4WFAW 1VQ5W 5M1AA 3PIOW 1LZWA 2WA9A 3G4SW 1VQNW 4WF9W 3W7XA 3G19A 3G71W 4BL2A 5GAGa 3O1FB 2QEXW 5JVGW 1K73X 4BL3A 1MBUC 1N8RX 3CD6W 3CXCV 1M90X 1VQLW 5GAEa 4CPKA 5M19A 5JVHW 1MBVB 1KQSV 3CCJW 2ZJRW 1RQUA 4WFNW 4C1NA 1K8AX 3W7SA 3OW2V 1VQ7W 1M1KX 1VQOW 2W9RA 1RQSA 4YKAA 3I56W 1DD3A 5DM6W 2OTLW 1VQKW 4CJNA 1K9MX 1VQ6W 1VQ9W 1MBXC 1VQPW 4UY8Z 3CC2W 5CA3A 4YJMA 4IOCW 3O2HA 3DNJA 4WFBW 2ZJQW 1MWUA 3CC7W 1QVFV 3O2OA 4YJXA 3G1BA 3ZG5A 1YJ9W 1YJNW 4U67W 1VQQA 1YJWW 3W7UA 3ZFZA 3CCQW 3GQ0A 2QA4W 3CPWV 1CTFA 3D3IA 3CCRW 3GQ1A 1MWTA 1Q86X 3GW1A 1Q82X 5GAHa 4WCEW 2ZJPW 3CCUW 4IO9W 1VQMW 1NJIX 3CCEW 1Q7YX 1MWSA 3G6EW 4DKIA 3CCMW 3CMAW 3DLLW 3CF5W 3G3PA 5M18A 1MWRA 1YHQW 1YI2W 3CCLW 1BXYA 1DD4A 2OTJW 3O2BA 2WA8A 4IOAW
chains in the Genus database with same CATH topology
1KC8X 1VQ4W 3CMEW 3I55W 1YIJW 1VQ8W 5HL7W 3CCSW 1QVGV 3J7ZZ 3CCVW 5DM7W 3CC4W 1YITW 1Q81X 1W2BV 1JJ2V 1S72W 1KD1X 3PIPW 5GADa 4WFAW 1VQ5W 3PIOW 3G4SW 1VQNW 4WF9W 3G71W 5GAGa 2QEXW 5JVGW 1K73X 1N8RX 3CD6W 3CXCV 1M90X 1VQLW 5GAEa 5JVHW 1KQSV 3CCJW 2ZJRW 4WFNW 4C1NA 1K8AX 3OW2V 1VQ7W 1M1KX 1VQOW 3I56W 5DM6W 2OTLW 1VQKW 1K9MX 1VQ6W 1VQ9W 1VQPW 4UY8Z 3CC2W 4IOCW 4WFBW 2ZJQW 3CC7W 1QVFV 1YJ9W 1YJNW 4U67W 1YJWW 3CCQW 2QA4W 3CPWV 3CCRW 1Q86X 1Q82X 5GAHa 4WCEW 2ZJPW 3CCUW 4IO9W 1VQMW 1NJIX 3CCEW 1Q7YX 3G6EW 3CCMW 3CMAW 3DLLW 3CF5W 1YHQW 1YI2W 3CCLW 1BXYA 2OTJW 4IOAW
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KC8 X;  1VQ4 W;  3CME W;  3I55 W;  1YIJ W;  1VQ8 W;  5HL7 W;  3CCS W;  1QVG V;  3J7Z Z;  3CCV W;  5DM7 W;  3CC4 W;  1YIT W;  1Q81 X;  1W2B V;  1JJ2 V;  1S72 W;  1KD1 X;  3PIP W;  5GAD a;  4WFA W;  1VQ5 W;  3PIO W;  3G4S W;  1VQN W;  4WF9 W;  3G71 W;  5GAG a;  2QEX W;  5JVG W;  1K73 X;  1N8R X;  3CD6 W;  3CXC V;  1M90 X;  1VQL W;  5GAE a;  5JVH W;  1KQS V;  3CCJ W;  2ZJR W;  4WFN W;  1K8A X;  3OW2 V;  1VQ7 W;  1M1K X;  1VQO W;  3I56 W;  5DM6 W;  2OTL W;  1VQK W;  1K9M X;  1VQ6 W;  1VQ9 W;  1VQP W;  4UY8 Z;  3CC2 W;  4IOC W;  4WFB W;  2ZJQ W;  3CC7 W;  1QVF V;  1YJ9 W;  1YJN W;  4U67 W;  1YJW W;  3CCQ W;  2QA4 W;  3CPW V;  3CCR W;  1Q86 X;  1Q82 X;  5GAH a;  4WCE W;  2ZJP W;  3CCU W;  4IO9 W;  1VQM W;  1NJI X;  3CCE W;  1Q7Y X;  3G6E W;  3CCM W;  3CMA W;  3DLL W;  3CF5 W;  1YHQ W;  1YI2 W;  3CCL W;  1BXY A;  2OTJ W;  4IOA W; 
#chains in the Genus database with same CATH topology
 1KC8 X;  1VQ4 W;  3CME W;  1R6O C;  1R6Q C;  3I55 W;  3W7W A;  1YIJ W;  1VQ8 W;  5HL7 W;  5GW7 A;  3CCS W;  1QVG V;  3J7Z Z;  3CCV W;  5DM7 W;  3CC4 W;  1YIT W;  1Q81 X;  1W2B V;  3W7T A;  1JJ2 V;  1S72 W;  3ZG0 A;  3O1F A;  1RQV A;  1MG9 A;  1KD1 X;  3PIP W;  5GAD a;  4WFA W;  1VQ5 W;  5M1A A;  3PIO W;  1LZW A;  2WA9 A;  3G4S W;  1VQN W;  4WF9 W;  3W7X A;  3G19 A;  3G71 W;  4BL2 A;  5GAG a;  3O1F B;  2QEX W;  5JVG W;  1K73 X;  4BL3 A;  1MBU C;  1N8R X;  3CD6 W;  3CXC V;  1M90 X;  1VQL W;  5GAE a;  4CPK A;  5M19 A;  5JVH W;  1MBV B;  1KQS V;  3CCJ W;  2ZJR W;  1RQU A;  4WFN W;  4C1N A;  1K8A X;  3W7S A;  3OW2 V;  1VQ7 W;  1M1K X;  1VQO W;  2W9R A;  1RQS A;  4YKA A;  3I56 W;  1DD3 A;  5DM6 W;  2OTL W;  1VQK W;  4CJN A;  1K9M X;  1VQ6 W;  1VQ9 W;  1MBX C;  1VQP W;  4UY8 Z;  3CC2 W;  5CA3 A;  4YJM A;  4IOC W;  3O2H A;  3DNJ A;  4WFB W;  2ZJQ W;  1MWU A;  3CC7 W;  1QVF V;  3O2O A;  4YJX A;  3G1B A;  3ZG5 A;  1YJ9 W;  1YJN W;  4U67 W;  1VQQ A;  1YJW W;  3W7U A;  3ZFZ A;  3CCQ W;  3GQ0 A;  2QA4 W;  3CPW V;  1CTF A;  3D3I A;  3CCR W;  3GQ1 A;  1MWT A;  1Q86 X;  3GW1 A;  1Q82 X;  5GAH a;  4WCE W;  2ZJP W;  3CCU W;  4IO9 W;  1VQM W;  1NJI X;  3CCE W;  1Q7Y X;  1MWS A;  3G6E W;  4DKI A;  3CCM W;  3CMA W;  3DLL W;  3CF5 W;  3G3P A;  5M18 A;  1MWR A;  1YHQ W;  1YI2 W;  3CCL W;  1BXY A;  1DD4 A;  2OTJ W;  3O2B A;  2WA8 A;  4IOA W; 
#chains in the Genus database with same CATH homology
 1KC8 X;  1VQ4 W;  3CME W;  3I55 W;  1YIJ W;  1VQ8 W;  5HL7 W;  3CCS W;  1QVG V;  3J7Z Z;  3CCV W;  5DM7 W;  3CC4 W;  1YIT W;  1Q81 X;  1W2B V;  1JJ2 V;  1S72 W;  1KD1 X;  3PIP W;  5GAD a;  4WFA W;  1VQ5 W;  3PIO W;  3G4S W;  1VQN W;  4WF9 W;  3G71 W;  5GAG a;  2QEX W;  5JVG W;  1K73 X;  1N8R X;  3CD6 W;  3CXC V;  1M90 X;  1VQL W;  5GAE a;  5JVH W;  1KQS V;  3CCJ W;  2ZJR W;  4WFN W;  4C1N A;  1K8A X;  3OW2 V;  1VQ7 W;  1M1K X;  1VQO W;  3I56 W;  5DM6 W;  2OTL W;  1VQK W;  1K9M X;  1VQ6 W;  1VQ9 W;  1VQP W;  4UY8 Z;  3CC2 W;  4IOC W;  4WFB W;  2ZJQ W;  3CC7 W;  1QVF V;  1YJ9 W;  1YJN W;  4U67 W;  1YJW W;  3CCQ W;  2QA4 W;  3CPW V;  3CCR W;  1Q86 X;  1Q82 X;  5GAH a;  4WCE W;  2ZJP W;  3CCU W;  4IO9 W;  1VQM W;  1NJI X;  3CCE W;  1Q7Y X;  3G6E W;  3CCM W;  3CMA W;  3DLL W;  3CF5 W;  1YHQ W;  1YI2 W;  3CCL W;  1BXY A;  2OTJ W;  4IOA W; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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