3CCLW

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535c. density for anisomycin is visible but not included in model.
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 49
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3cclW02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 3cclW01
1VQ5W 5GAHa 1S72W 5DM7W 3CCSW 1VQPW 1VQLW 2OTLW 1YJ9W 2OTJW 3J7ZZ 4UY8Z 1N8RX 1VQOW 3CF5W 3CD6W 1YI2W 1YJNW 4WCEW 2QEXW 1VQ9W 1K73X 3CCVW 4WFBW 3OW2V 1QVGV 3CCEW 3DLLW 1VQ4W 1VQNW 4WFAW 5GAEa 3CPWV 1JJ2V 3CCLW 5DM6W 1VQKW 1VQ6W 4U67W 2ZJRW 3PIOW 3CMEW 3I55W 4WFNW 1KC8X 5JVHW 3CC7W 1W2BV 1YJWW 3PIPW 5GAGa 3G6EW 1VQ7W 3CXCV 1M90X 2QA4W 3G4SW 1KQSV 4IOAW 3CCRW 2ZJPW 3I56W 1K8AX 3CCUW 2ZJQW 1VQMW 1YIJW 3CCJW 5JVGW 1Q81X 1Q82X 4IOCW 1Q7YX 3CMAW 1KD1X 4IO9W 4WF9W 1M1KX 3CCQW 1Q86X 1NJIX 3G71W 1YHQW 1QVFV 3CC4W 3CC2W 3CCMW 1BXYA 5HL7W 5GADa 1YITW 1K9MX 1VQ8W
chains in the Genus database with same CATH superfamily
1VQ5W 3ZFZA 3D3IA 5GAHa 1S72W 3G3PA 5DM7W 3GQ1A 3CCSW 1VQPW 1VQLW 2OTLW 1YJ9W 1MBXC 4CJNA 1RQVA 5CA3A 3O1FA 2OTJW 1MWRA 3J7ZZ 4UY8Z 1N8RX 1MWUA 1VQOW 3CF5W 3CD6W 1YI2W 1YJNW 5M19A 4WCEW 1DD3A 3DNJA 2QEXW 1VQ9W 1K73X 2WA8A 3CCVW 4C1NA 4WFBW 3OW2V 4YJXA 1QVGV 3CCEW 3DLLW 3O2HA 3W7UA 1VQ4W 1VQNW 4WFAW 2WA9A 5GAEa 4YKAA 3GW1A 2W9RA 3CPWV 3W7TA 1JJ2V 4BL3A 1RQSA 3CCLW 3G19A 1LZWA 5DM6W 1VQKW 1VQ6W 4U67W 2ZJRW 4BL2A 3PIOW 3CMEW 3I55W 4WFNW 1KC8X 3O1FB 5JVHW 3CC7W 1W2BV 3O2BA 1YJWW 3PIPW 4YJMA 5GAGa 1CTFA 3W7WA 3ZG5A 3G6EW 1VQ7W 3CXCV 1M90X 2QA4W 3G4SW 1KQSV 1RQUA 4IOAW 3CCRW 2ZJPW 3I56W 1K8AX 3ZG0A 5GW7A 3CCUW 2ZJQW 1VQMW 5M18A 1MBVB 1R6OC 1YIJW 3CCJW 3GQ0A 1MWSA 5JVGW 1Q81X 3O2OA 1Q82X 4IOCW 1Q7YX 1MWTA 3CMAW 3W7SA 1DD4A 4CPKA 1KD1X 4IO9W 4WF9W 1M1KX 1MBUC 5M1AA 3CCQW 1Q86X 1NJIX 3G71W 3W7XA 1VQQA 1R6QC 1YHQW 1QVFV 3CC4W 1MG9A 3CC2W 3CCMW 1BXYA 5HL7W 5GADa 1YITW 4DKIA 1K9MX 3G1BA 1VQ8W
chains in the Genus database with same CATH topology
1VQ5W 5GAHa 1S72W 5DM7W 3CCSW 1VQPW 1VQLW 2OTLW 1YJ9W 2OTJW 3J7ZZ 4UY8Z 1N8RX 1VQOW 3CF5W 3CD6W 1YI2W 1YJNW 4WCEW 2QEXW 1VQ9W 1K73X 3CCVW 4C1NA 4WFBW 3OW2V 1QVGV 3CCEW 3DLLW 1VQ4W 1VQNW 4WFAW 5GAEa 3CPWV 1JJ2V 3CCLW 5DM6W 1VQKW 1VQ6W 4U67W 2ZJRW 3PIOW 3CMEW 3I55W 4WFNW 1KC8X 5JVHW 3CC7W 1W2BV 1YJWW 3PIPW 5GAGa 3G6EW 1VQ7W 3CXCV 1M90X 2QA4W 3G4SW 1KQSV 4IOAW 3CCRW 2ZJPW 3I56W 1K8AX 3CCUW 2ZJQW 1VQMW 1YIJW 3CCJW 5JVGW 1Q81X 1Q82X 4IOCW 1Q7YX 3CMAW 1KD1X 4IO9W 4WF9W 1M1KX 3CCQW 1Q86X 1NJIX 3G71W 1YHQW 1QVFV 3CC4W 3CC2W 3CCMW 1BXYA 5HL7W 5GADa 1YITW 1K9MX 1VQ8W
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQ5 W;  5GAH a;  1S72 W;  5DM7 W;  3CCS W;  1VQP W;  1VQL W;  2OTL W;  1YJ9 W;  2OTJ W;  3J7Z Z;  4UY8 Z;  1N8R X;  1VQO W;  3CF5 W;  3CD6 W;  1YI2 W;  1YJN W;  4WCE W;  2QEX W;  1VQ9 W;  1K73 X;  3CCV W;  4WFB W;  3OW2 V;  1QVG V;  3CCE W;  3DLL W;  1VQ4 W;  1VQN W;  4WFA W;  5GAE a;  3CPW V;  1JJ2 V;  3CCL W;  5DM6 W;  1VQK W;  1VQ6 W;  4U67 W;  2ZJR W;  3PIO W;  3CME W;  3I55 W;  4WFN W;  1KC8 X;  5JVH W;  3CC7 W;  1W2B V;  1YJW W;  3PIP W;  5GAG a;  3G6E W;  1VQ7 W;  3CXC V;  1M90 X;  2QA4 W;  3G4S W;  1KQS V;  4IOA W;  3CCR W;  2ZJP W;  3I56 W;  1K8A X;  3CCU W;  2ZJQ W;  1VQM W;  1YIJ W;  3CCJ W;  5JVG W;  1Q81 X;  1Q82 X;  4IOC W;  1Q7Y X;  3CMA W;  1KD1 X;  4IO9 W;  4WF9 W;  1M1K X;  3CCQ W;  1Q86 X;  1NJI X;  3G71 W;  1YHQ W;  1QVF V;  3CC4 W;  3CC2 W;  3CCM W;  1BXY A;  5HL7 W;  5GAD a;  1YIT W;  1K9M X;  1VQ8 W; 
#chains in the Genus database with same CATH topology
 1VQ5 W;  3ZFZ A;  3D3I A;  5GAH a;  1S72 W;  3G3P A;  5DM7 W;  3GQ1 A;  3CCS W;  1VQP W;  1VQL W;  2OTL W;  1YJ9 W;  1MBX C;  4CJN A;  1RQV A;  5CA3 A;  3O1F A;  2OTJ W;  1MWR A;  3J7Z Z;  4UY8 Z;  1N8R X;  1MWU A;  1VQO W;  3CF5 W;  3CD6 W;  1YI2 W;  1YJN W;  5M19 A;  4WCE W;  1DD3 A;  3DNJ A;  2QEX W;  1VQ9 W;  1K73 X;  2WA8 A;  3CCV W;  4C1N A;  4WFB W;  3OW2 V;  4YJX A;  1QVG V;  3CCE W;  3DLL W;  3O2H A;  3W7U A;  1VQ4 W;  1VQN W;  4WFA W;  2WA9 A;  5GAE a;  4YKA A;  3GW1 A;  2W9R A;  3CPW V;  3W7T A;  1JJ2 V;  4BL3 A;  1RQS A;  3CCL W;  3G19 A;  1LZW A;  5DM6 W;  1VQK W;  1VQ6 W;  4U67 W;  2ZJR W;  4BL2 A;  3PIO W;  3CME W;  3I55 W;  4WFN W;  1KC8 X;  3O1F B;  5JVH W;  3CC7 W;  1W2B V;  3O2B A;  1YJW W;  3PIP W;  4YJM A;  5GAG a;  1CTF A;  3W7W A;  3ZG5 A;  3G6E W;  1VQ7 W;  3CXC V;  1M90 X;  2QA4 W;  3G4S W;  1KQS V;  1RQU A;  4IOA W;  3CCR W;  2ZJP W;  3I56 W;  1K8A X;  3ZG0 A;  5GW7 A;  3CCU W;  2ZJQ W;  1VQM W;  5M18 A;  1MBV B;  1R6O C;  1YIJ W;  3CCJ W;  3GQ0 A;  1MWS A;  5JVG W;  1Q81 X;  3O2O A;  1Q82 X;  4IOC W;  1Q7Y X;  1MWT A;  3CMA W;  3W7S A;  1DD4 A;  4CPK A;  1KD1 X;  4IO9 W;  4WF9 W;  1M1K X;  1MBU C;  5M1A A;  3CCQ W;  1Q86 X;  1NJI X;  3G71 W;  3W7X A;  1VQQ A;  1R6Q C;  1YHQ W;  1QVF V;  3CC4 W;  1MG9 A;  3CC2 W;  3CCM W;  1BXY A;  5HL7 W;  5GAD a;  1YIT W;  4DKI A;  1K9M X;  3G1B A;  1VQ8 W; 
#chains in the Genus database with same CATH homology
 1VQ5 W;  5GAH a;  1S72 W;  5DM7 W;  3CCS W;  1VQP W;  1VQL W;  2OTL W;  1YJ9 W;  2OTJ W;  3J7Z Z;  4UY8 Z;  1N8R X;  1VQO W;  3CF5 W;  3CD6 W;  1YI2 W;  1YJN W;  4WCE W;  2QEX W;  1VQ9 W;  1K73 X;  3CCV W;  4C1N A;  4WFB W;  3OW2 V;  1QVG V;  3CCE W;  3DLL W;  1VQ4 W;  1VQN W;  4WFA W;  5GAE a;  3CPW V;  1JJ2 V;  3CCL W;  5DM6 W;  1VQK W;  1VQ6 W;  4U67 W;  2ZJR W;  3PIO W;  3CME W;  3I55 W;  4WFN W;  1KC8 X;  5JVH W;  3CC7 W;  1W2B V;  1YJW W;  3PIP W;  5GAG a;  3G6E W;  1VQ7 W;  3CXC V;  1M90 X;  2QA4 W;  3G4S W;  1KQS V;  4IOA W;  3CCR W;  2ZJP W;  3I56 W;  1K8A X;  3CCU W;  2ZJQ W;  1VQM W;  1YIJ W;  3CCJ W;  5JVG W;  1Q81 X;  1Q82 X;  4IOC W;  1Q7Y X;  3CMA W;  1KD1 X;  4IO9 W;  4WF9 W;  1M1K X;  3CCQ W;  1Q86 X;  1NJI X;  3G71 W;  1YHQ W;  1QVF V;  3CC4 W;  3CC2 W;  3CCM W;  1BXY A;  5HL7 W;  5GAD a;  1YIT W;  1K9M X;  1VQ8 W; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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