3CCMW

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2611u
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 52
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3ccmW02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 3ccmW01
1K9MX 5DM7W 1KD1X 1VQ8W 1YHQW 3CD6W 3J7ZZ 1YJNW 3CCEW 1YJ9W 4WCEW 1VQOW 1VQPW 1YITW 5JVGW 2OTLW 3CMAW 2QA4W 1YIJW 2ZJRW 1Q86X 1Q7YX 3CCUW 4WFBW 4UY8Z 5GAHa 1VQ5W 4IO9W 1S72W 5GAGa 3CC7W 5GADa 3CCQW 1K8AX 1M1KX 3DLLW 2ZJQW 3CC2W 1N8RX 5DM6W 3G4SW 1VQ4W 1Q81X 3OW2V 3CF5W 5JVHW 3I55W 1KC8X 1W2BV 3CMEW 4U67W 3PIPW 3G6EW 1VQLW 4WFNW 1QVGV 3CCVW 3CPWV 4WF9W 1VQ9W 1YJWW 4WFAW 1YI2W 5HL7W 3PIOW 1NJIX 1VQ7W 3CCJW 3I56W 3CC4W 1VQ6W 4IOAW 3CCRW 3CXCV 1JJ2V 1KQSV 3G71W 1VQNW 2OTJW 1Q82X 1M90X 1BXYA 4IOCW 3CCSW 1VQKW 2QEXW 3CCMW 1VQMW 3CCLW 2ZJPW 1K73X 1QVFV 5GAEa
chains in the Genus database with same CATH superfamily
2WA9A 3G3PA 1K9MX 5DM7W 1KD1X 3D3IA 1VQ8W 1YHQW 3CD6W 3J7ZZ 1DD4A 1YJNW 3GQ1A 3CCEW 1YJ9W 4WCEW 1VQOW 1VQPW 1R6QC 1MWTA 3W7TA 1R6OC 3ZG0A 1YITW 5JVGW 2OTLW 3CMAW 2QA4W 1YIJW 2ZJRW 3O2HA 1Q86X 5M19A 1Q7YX 3CCUW 4WFBW 4UY8Z 5GAHa 1VQ5W 4IO9W 4YJMA 1S72W 1VQQA 5M18A 3GW1A 3ZG5A 5GAGa 1RQUA 1CTFA 3CC7W 5GADa 3CCQW 4YKAA 1K8AX 5CA3A 5GW7A 1M1KX 3G1BA 3DLLW 2W9RA 2ZJQW 3CC2W 1N8RX 5DM6W 4YJXA 3G4SW 1MWRA 1VQ4W 3GQ0A 4BL2A 3O1FB 1Q81X 3OW2V 3CF5W 5JVHW 3I55W 5M1AA 3ZFZA 3DNJA 4BL3A 1KC8X 1W2BV 3CMEW 4U67W 3PIPW 3O2BA 3G6EW 1VQLW 4WFNW 1QVGV 3CCVW 3CPWV 3W7SA 4WF9W 1VQ9W 1RQSA 1RQVA 3O1FA 1YJWW 4WFAW 1YI2W 5HL7W 4DKIA 3G19A 3W7WA 3PIOW 1NJIX 2WA8A 1VQ7W 4CJNA 3CCJW 3I56W 3CC4W 4CPKA 1VQ6W 3W7XA 4IOAW 1MBXC 1MWSA 3CCRW 3CXCV 1JJ2V 1MWUA 1KQSV 3G71W 1VQNW 3W7UA 1MBUC 2OTJW 1Q82X 1M90X 1BXYA 4IOCW 1MG9A 3O2OA 3CCSW 1VQKW 2QEXW 3CCMW 1MBVB 1VQMW 3CCLW 4C1NA 1LZWA 2ZJPW 1K73X 1DD3A 1QVFV 5GAEa
chains in the Genus database with same CATH topology
1K9MX 5DM7W 1KD1X 1VQ8W 1YHQW 3CD6W 3J7ZZ 1YJNW 3CCEW 1YJ9W 4WCEW 1VQOW 1VQPW 1YITW 5JVGW 2OTLW 3CMAW 2QA4W 1YIJW 2ZJRW 1Q86X 1Q7YX 3CCUW 4WFBW 4UY8Z 5GAHa 1VQ5W 4IO9W 1S72W 5GAGa 3CC7W 5GADa 3CCQW 1K8AX 1M1KX 3DLLW 2ZJQW 3CC2W 1N8RX 5DM6W 3G4SW 1VQ4W 1Q81X 3OW2V 3CF5W 5JVHW 3I55W 1KC8X 1W2BV 3CMEW 4U67W 3PIPW 3G6EW 1VQLW 4WFNW 1QVGV 3CCVW 3CPWV 4WF9W 1VQ9W 1YJWW 4WFAW 1YI2W 5HL7W 3PIOW 1NJIX 1VQ7W 3CCJW 3I56W 3CC4W 1VQ6W 4IOAW 3CCRW 3CXCV 1JJ2V 1KQSV 3G71W 1VQNW 2OTJW 1Q82X 1M90X 1BXYA 4IOCW 3CCSW 1VQKW 2QEXW 3CCMW 1VQMW 3CCLW 4C1NA 2ZJPW 1K73X 1QVFV 5GAEa
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1K9M X;  5DM7 W;  1KD1 X;  1VQ8 W;  1YHQ W;  3CD6 W;  3J7Z Z;  1YJN W;  3CCE W;  1YJ9 W;  4WCE W;  1VQO W;  1VQP W;  1YIT W;  5JVG W;  2OTL W;  3CMA W;  2QA4 W;  1YIJ W;  2ZJR W;  1Q86 X;  1Q7Y X;  3CCU W;  4WFB W;  4UY8 Z;  5GAH a;  1VQ5 W;  4IO9 W;  1S72 W;  5GAG a;  3CC7 W;  5GAD a;  3CCQ W;  1K8A X;  1M1K X;  3DLL W;  2ZJQ W;  3CC2 W;  1N8R X;  5DM6 W;  3G4S W;  1VQ4 W;  1Q81 X;  3OW2 V;  3CF5 W;  5JVH W;  3I55 W;  1KC8 X;  1W2B V;  3CME W;  4U67 W;  3PIP W;  3G6E W;  1VQL W;  4WFN W;  1QVG V;  3CCV W;  3CPW V;  4WF9 W;  1VQ9 W;  1YJW W;  4WFA W;  1YI2 W;  5HL7 W;  3PIO W;  1NJI X;  1VQ7 W;  3CCJ W;  3I56 W;  3CC4 W;  1VQ6 W;  4IOA W;  3CCR W;  3CXC V;  1JJ2 V;  1KQS V;  3G71 W;  1VQN W;  2OTJ W;  1Q82 X;  1M90 X;  1BXY A;  4IOC W;  3CCS W;  1VQK W;  2QEX W;  3CCM W;  1VQM W;  3CCL W;  2ZJP W;  1K73 X;  1QVF V;  5GAE a; 
#chains in the Genus database with same CATH topology
 2WA9 A;  3G3P A;  1K9M X;  5DM7 W;  1KD1 X;  3D3I A;  1VQ8 W;  1YHQ W;  3CD6 W;  3J7Z Z;  1DD4 A;  1YJN W;  3GQ1 A;  3CCE W;  1YJ9 W;  4WCE W;  1VQO W;  1VQP W;  1R6Q C;  1MWT A;  3W7T A;  1R6O C;  3ZG0 A;  1YIT W;  5JVG W;  2OTL W;  3CMA W;  2QA4 W;  1YIJ W;  2ZJR W;  3O2H A;  1Q86 X;  5M19 A;  1Q7Y X;  3CCU W;  4WFB W;  4UY8 Z;  5GAH a;  1VQ5 W;  4IO9 W;  4YJM A;  1S72 W;  1VQQ A;  5M18 A;  3GW1 A;  3ZG5 A;  5GAG a;  1RQU A;  1CTF A;  3CC7 W;  5GAD a;  3CCQ W;  4YKA A;  1K8A X;  5CA3 A;  5GW7 A;  1M1K X;  3G1B A;  3DLL W;  2W9R A;  2ZJQ W;  3CC2 W;  1N8R X;  5DM6 W;  4YJX A;  3G4S W;  1MWR A;  1VQ4 W;  3GQ0 A;  4BL2 A;  3O1F B;  1Q81 X;  3OW2 V;  3CF5 W;  5JVH W;  3I55 W;  5M1A A;  3ZFZ A;  3DNJ A;  4BL3 A;  1KC8 X;  1W2B V;  3CME W;  4U67 W;  3PIP W;  3O2B A;  3G6E W;  1VQL W;  4WFN W;  1QVG V;  3CCV W;  3CPW V;  3W7S A;  4WF9 W;  1VQ9 W;  1RQS A;  1RQV A;  3O1F A;  1YJW W;  4WFA W;  1YI2 W;  5HL7 W;  4DKI A;  3G19 A;  3W7W A;  3PIO W;  1NJI X;  2WA8 A;  1VQ7 W;  4CJN A;  3CCJ W;  3I56 W;  3CC4 W;  4CPK A;  1VQ6 W;  3W7X A;  4IOA W;  1MBX C;  1MWS A;  3CCR W;  3CXC V;  1JJ2 V;  1MWU A;  1KQS V;  3G71 W;  1VQN W;  3W7U A;  1MBU C;  2OTJ W;  1Q82 X;  1M90 X;  1BXY A;  4IOC W;  1MG9 A;  3O2O A;  3CCS W;  1VQK W;  2QEX W;  3CCM W;  1MBV B;  1VQM W;  3CCL W;  4C1N A;  1LZW A;  2ZJP W;  1K73 X;  1DD3 A;  1QVF V;  5GAE a; 
#chains in the Genus database with same CATH homology
 1K9M X;  5DM7 W;  1KD1 X;  1VQ8 W;  1YHQ W;  3CD6 W;  3J7Z Z;  1YJN W;  3CCE W;  1YJ9 W;  4WCE W;  1VQO W;  1VQP W;  1YIT W;  5JVG W;  2OTL W;  3CMA W;  2QA4 W;  1YIJ W;  2ZJR W;  1Q86 X;  1Q7Y X;  3CCU W;  4WFB W;  4UY8 Z;  5GAH a;  1VQ5 W;  4IO9 W;  1S72 W;  5GAG a;  3CC7 W;  5GAD a;  3CCQ W;  1K8A X;  1M1K X;  3DLL W;  2ZJQ W;  3CC2 W;  1N8R X;  5DM6 W;  3G4S W;  1VQ4 W;  1Q81 X;  3OW2 V;  3CF5 W;  5JVH W;  3I55 W;  1KC8 X;  1W2B V;  3CME W;  4U67 W;  3PIP W;  3G6E W;  1VQL W;  4WFN W;  1QVG V;  3CCV W;  3CPW V;  4WF9 W;  1VQ9 W;  1YJW W;  4WFA W;  1YI2 W;  5HL7 W;  3PIO W;  1NJI X;  1VQ7 W;  3CCJ W;  3I56 W;  3CC4 W;  1VQ6 W;  4IOA W;  3CCR W;  3CXC V;  1JJ2 V;  1KQS V;  3G71 W;  1VQN W;  2OTJ W;  1Q82 X;  1M90 X;  1BXY A;  4IOC W;  3CCS W;  1VQK W;  2QEX W;  3CCM W;  1VQM W;  3CCL W;  4C1N A;  2ZJP W;  1K73 X;  1QVF V;  5GAE a; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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