3CCQW

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488u
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ribosome
publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule keywords 50S ribosomal protein L2P
total genus 50
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3ccqW02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 3ccqW01
5GAEa 5DM6W 3CCSW 3CCUW 3CC7W 1Q86X 1VQ6W 3PIOW 2OTLW 1YHQW 5GAHa 1KD1X 4WFAW 1KQSV 1YITW 1QVGV 3OW2V 1VQ5W 5JVGW 4IO9W 3G71W 4UY8Z 2OTJW 2QEXW 1NJIX 1VQKW 4U67W 4WFBW 3G4SW 3CMEW 5GADa 3CCQW 3CCLW 1N8RX 1VQOW 3CCJW 3CCRW 3I55W 1VQ4W 5HL7W 1K9MX 1Q81X 1VQLW 1VQ8W 2ZJQW 1YJWW 3PIPW 4IOAW 1VQPW 3CMAW 1YI2W 1W2BV 3CCMW 1S72W 1YJ9W 3CCVW 1K73X 2ZJPW 3CC4W 3DLLW 1Q7YX 4WCEW 4WFNW 2ZJRW 1M90X 3CF5W 1K8AX 3CPWV 1VQMW 4IOCW 5JVHW 1YJNW 1QVFV 3CC2W 1BXYA 1M1KX 1VQ7W 5DM7W 1Q82X 3G6EW 3CCEW 4WF9W 2QA4W 1VQNW 3I56W 1VQ9W 1KC8X 3CXCV 5GAGa 1YIJW 3J7ZZ 3CD6W 1JJ2V
chains in the Genus database with same CATH superfamily
3ZG0A 1MWUA 5GAEa 4YKAA 5DM6W 1R6OC 3CCSW 1MBVB 3CCUW 5M1AA 3CC7W 5M19A 3W7TA 1RQVA 5CA3A 1Q86X 1VQ6W 3DNJA 3PIOW 2OTLW 1YHQW 5GAHa 3GW1A 1KD1X 4WFAW 1KQSV 1YITW 1QVGV 3OW2V 1VQ5W 3D3IA 3ZFZA 3G71W 5JVGW 4IO9W 2OTJW 4UY8Z 2QEXW 1NJIX 1VQKW 4U67W 3ZG5A 4WFBW 3G4SW 1DD3A 3CMEW 3O2BA 5GADa 3CCQW 3G3PA 3CCLW 1N8RX 3W7UA 1RQSA 1VQOW 2W9RA 3CCJW 1MBXC 1DD4A 3CCRW 3I55W 4BL3A 3GQ1A 1VQ4W 5HL7W 3O2OA 1RQUA 4CPKA 1K9MX 1Q81X 1VQLW 1VQ8W 2ZJQW 1YJWW 3PIPW 1CTFA 4IOAW 1VQPW 3G1BA 3G19A 3CMAW 1YI2W 3W7SA 1W2BV 3W7XA 3CCMW 5M18A 1MG9A 5GW7A 1S72W 1MWRA 1YJ9W 4YJXA 3W7WA 3CCVW 1K73X 4C1NA 2ZJPW 3CC4W 3DLLW 1Q7YX 4WCEW 1LZWA 4BL2A 4WFNW 2WA9A 1M90X 2ZJRW 1K8AX 3O1FB 3CF5W 1VQQA 3CPWV 1VQMW 4YJMA 4IOCW 5JVHW 1YJNW 4DKIA 1QVFV 3CC2W 1BXYA 1M1KX 1VQ7W 1MBUC 5DM7W 1Q82X 3G6EW 2WA8A 3CCEW 1R6QC 4WF9W 2QA4W 1VQNW 3I56W 3O2HA 3GQ0A 1VQ9W 1KC8X 3O1FA 3CXCV 5GAGa 1MWSA 4CJNA 1MWTA 1YIJW 3J7ZZ 3CD6W 1JJ2V
chains in the Genus database with same CATH topology
5GAEa 5DM6W 3CCSW 3CCUW 3CC7W 1Q86X 1VQ6W 3PIOW 2OTLW 1YHQW 5GAHa 1KD1X 4WFAW 1KQSV 1YITW 1QVGV 3OW2V 1VQ5W 5JVGW 4IO9W 3G71W 4UY8Z 2OTJW 2QEXW 1NJIX 1VQKW 4U67W 4WFBW 3G4SW 3CMEW 5GADa 3CCQW 3CCLW 1N8RX 1VQOW 3CCJW 3CCRW 3I55W 1VQ4W 5HL7W 1K9MX 1Q81X 1VQLW 1VQ8W 2ZJQW 1YJWW 3PIPW 4IOAW 1VQPW 3CMAW 1YI2W 1W2BV 3CCMW 1S72W 1YJ9W 3CCVW 1K73X 4C1NA 2ZJPW 3CC4W 3DLLW 1Q7YX 4WCEW 4WFNW 2ZJRW 1M90X 3CF5W 1K8AX 3CPWV 1VQMW 4IOCW 5JVHW 1YJNW 1QVFV 3CC2W 1BXYA 1M1KX 1VQ7W 5DM7W 1Q82X 3G6EW 3CCEW 4WF9W 2QA4W 1VQNW 3I56W 1VQ9W 1KC8X 3CXCV 5GAGa 1YIJW 3J7ZZ 3CD6W 1JJ2V
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GAE a;  5DM6 W;  3CCS W;  3CCU W;  3CC7 W;  1Q86 X;  1VQ6 W;  3PIO W;  2OTL W;  1YHQ W;  5GAH a;  1KD1 X;  4WFA W;  1KQS V;  1YIT W;  1QVG V;  3OW2 V;  1VQ5 W;  5JVG W;  4IO9 W;  3G71 W;  4UY8 Z;  2OTJ W;  2QEX W;  1NJI X;  1VQK W;  4U67 W;  4WFB W;  3G4S W;  3CME W;  5GAD a;  3CCQ W;  3CCL W;  1N8R X;  1VQO W;  3CCJ W;  3CCR W;  3I55 W;  1VQ4 W;  5HL7 W;  1K9M X;  1Q81 X;  1VQL W;  1VQ8 W;  2ZJQ W;  1YJW W;  3PIP W;  4IOA W;  1VQP W;  3CMA W;  1YI2 W;  1W2B V;  3CCM W;  1S72 W;  1YJ9 W;  3CCV W;  1K73 X;  2ZJP W;  3CC4 W;  3DLL W;  1Q7Y X;  4WCE W;  4WFN W;  2ZJR W;  1M90 X;  3CF5 W;  1K8A X;  3CPW V;  1VQM W;  4IOC W;  5JVH W;  1YJN W;  1QVF V;  3CC2 W;  1BXY A;  1M1K X;  1VQ7 W;  5DM7 W;  1Q82 X;  3G6E W;  3CCE W;  4WF9 W;  2QA4 W;  1VQN W;  3I56 W;  1VQ9 W;  1KC8 X;  3CXC V;  5GAG a;  1YIJ W;  3J7Z Z;  3CD6 W;  1JJ2 V; 
#chains in the Genus database with same CATH topology
 3ZG0 A;  1MWU A;  5GAE a;  4YKA A;  5DM6 W;  1R6O C;  3CCS W;  1MBV B;  3CCU W;  5M1A A;  3CC7 W;  5M19 A;  3W7T A;  1RQV A;  5CA3 A;  1Q86 X;  1VQ6 W;  3DNJ A;  3PIO W;  2OTL W;  1YHQ W;  5GAH a;  3GW1 A;  1KD1 X;  4WFA W;  1KQS V;  1YIT W;  1QVG V;  3OW2 V;  1VQ5 W;  3D3I A;  3ZFZ A;  3G71 W;  5JVG W;  4IO9 W;  2OTJ W;  4UY8 Z;  2QEX W;  1NJI X;  1VQK W;  4U67 W;  3ZG5 A;  4WFB W;  3G4S W;  1DD3 A;  3CME W;  3O2B A;  5GAD a;  3CCQ W;  3G3P A;  3CCL W;  1N8R X;  3W7U A;  1RQS A;  1VQO W;  2W9R A;  3CCJ W;  1MBX C;  1DD4 A;  3CCR W;  3I55 W;  4BL3 A;  3GQ1 A;  1VQ4 W;  5HL7 W;  3O2O A;  1RQU A;  4CPK A;  1K9M X;  1Q81 X;  1VQL W;  1VQ8 W;  2ZJQ W;  1YJW W;  3PIP W;  1CTF A;  4IOA W;  1VQP W;  3G1B A;  3G19 A;  3CMA W;  1YI2 W;  3W7S A;  1W2B V;  3W7X A;  3CCM W;  5M18 A;  1MG9 A;  5GW7 A;  1S72 W;  1MWR A;  1YJ9 W;  4YJX A;  3W7W A;  3CCV W;  1K73 X;  4C1N A;  2ZJP W;  3CC4 W;  3DLL W;  1Q7Y X;  4WCE W;  1LZW A;  4BL2 A;  4WFN W;  2WA9 A;  1M90 X;  2ZJR W;  1K8A X;  3O1F B;  3CF5 W;  1VQQ A;  3CPW V;  1VQM W;  4YJM A;  4IOC W;  5JVH W;  1YJN W;  4DKI A;  1QVF V;  3CC2 W;  1BXY A;  1M1K X;  1VQ7 W;  1MBU C;  5DM7 W;  1Q82 X;  3G6E W;  2WA8 A;  3CCE W;  1R6Q C;  4WF9 W;  2QA4 W;  1VQN W;  3I56 W;  3O2H A;  3GQ0 A;  1VQ9 W;  1KC8 X;  3O1F A;  3CXC V;  5GAG a;  1MWS A;  4CJN A;  1MWT A;  1YIJ W;  3J7Z Z;  3CD6 W;  1JJ2 V; 
#chains in the Genus database with same CATH homology
 5GAE a;  5DM6 W;  3CCS W;  3CCU W;  3CC7 W;  1Q86 X;  1VQ6 W;  3PIO W;  2OTL W;  1YHQ W;  5GAH a;  1KD1 X;  4WFA W;  1KQS V;  1YIT W;  1QVG V;  3OW2 V;  1VQ5 W;  5JVG W;  4IO9 W;  3G71 W;  4UY8 Z;  2OTJ W;  2QEX W;  1NJI X;  1VQK W;  4U67 W;  4WFB W;  3G4S W;  3CME W;  5GAD a;  3CCQ W;  3CCL W;  1N8R X;  1VQO W;  3CCJ W;  3CCR W;  3I55 W;  1VQ4 W;  5HL7 W;  1K9M X;  1Q81 X;  1VQL W;  1VQ8 W;  2ZJQ W;  1YJW W;  3PIP W;  4IOA W;  1VQP W;  3CMA W;  1YI2 W;  1W2B V;  3CCM W;  1S72 W;  1YJ9 W;  3CCV W;  1K73 X;  4C1N A;  2ZJP W;  3CC4 W;  3DLL W;  1Q7Y X;  4WCE W;  4WFN W;  2ZJR W;  1M90 X;  3CF5 W;  1K8A X;  3CPW V;  1VQM W;  4IOC W;  5JVH W;  1YJN W;  1QVF V;  3CC2 W;  1BXY A;  1M1K X;  1VQ7 W;  5DM7 W;  1Q82 X;  3G6E W;  3CCE W;  4WF9 W;  2QA4 W;  1VQN W;  3I56 W;  1VQ9 W;  1KC8 X;  3CXC V;  5GAG a;  1YIJ W;  3J7Z Z;  3CD6 W;  1JJ2 V; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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