3CCSW

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2482a
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 46
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3ccsW02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 3ccsW01
1YHQW 1K73X 4IOAW 1Q81X 3CCJW 2ZJQW 1VQPW 1KC8X 5GAEa 2QA4W 3CF5W 4UY8Z 1VQKW 1M90X 2QEXW 1KQSV 3CXCV 1Q82X 3CCUW 1M1KX 3CC2W 5DM6W 3G6EW 3CMAW 1YI2W 1Q86X 1VQNW 1VQOW 3CMEW 5GAHa 3CCVW 1VQLW 1YJWW 4WF9W 3CCLW 4WFAW 4WFNW 3G4SW 4IO9W 3CC7W 1VQ7W 1YIJW 1K8AX 3OW2V 3CCMW 1YJ9W 3CD6W 5GADa 1N8RX 3I55W 1VQ5W 1QVFV 2ZJRW 1KD1X 3CCEW 1K9MX 2OTLW 1Q7YX 4U67W 1VQ9W 5GAGa 3CC4W 3DLLW 1YITW 1VQ4W 3CCSW 4WFBW 4WCEW 1S72W 1NJIX 3G71W 3PIPW 3CPWV 4IOCW 1YJNW 3PIOW 1QVGV 5DM7W 3CCRW 2ZJPW 1JJ2V 1VQ8W 5JVGW 3CCQW 1VQMW 2OTJW 1W2BV 1VQ6W 1BXYA 5JVHW 3J7ZZ 3I56W 5HL7W
chains in the Genus database with same CATH superfamily
1YHQW 1K73X 4IOAW 1DD4A 1Q81X 1R6OC 3CCJW 2ZJQW 3W7XA 2W9RA 1VQPW 1KC8X 5GAEa 1CTFA 1MWSA 2WA9A 2QA4W 3W7WA 1MG9A 3CF5W 4UY8Z 1VQKW 1M90X 4YJXA 2QEXW 1KQSV 3CXCV 1MBVB 3O1FB 1Q82X 3G1BA 3CCUW 1M1KX 1MWRA 3CC2W 5DM6W 3G6EW 3CMAW 1YI2W 1Q86X 1VQNW 4C1NA 1VQOW 3CMEW 5GAHa 3DNJA 3CCVW 1VQLW 1YJWW 3ZFZA 3CCLW 1MWUA 3W7UA 4WF9W 2WA8A 4WFAW 4DKIA 5M18A 4WFNW 1MBXC 3G4SW 3GW1A 5CA3A 4IO9W 3CC7W 1VQ7W 1YIJW 1K8AX 3OW2V 4CJNA 3CCMW 1YJ9W 3CD6W 5GADa 4BL3A 1N8RX 3I55W 1VQ5W 1QVFV 1DD3A 1LZWA 2ZJRW 1KD1X 4BL2A 3CCEW 1K9MX 1MBUC 2OTLW 3O2BA 1Q7YX 4U67W 1MWTA 3O2OA 3D3IA 3O1FA 1VQ9W 1RQUA 5GAGa 3CC4W 3GQ1A 1YITW 3DLLW 1VQ4W 3CCSW 1VQQA 4WFBW 4WCEW 4YKAA 1S72W 1NJIX 3G71W 3G3PA 5GW7A 3PIPW 3CPWV 3W7SA 4IOCW 1YJNW 1RQSA 3PIOW 1QVGV 5DM7W 3CCRW 3W7TA 2ZJPW 1JJ2V 1VQ8W 5JVGW 3CCQW 1VQMW 2OTJW 3O2HA 1W2BV 1VQ6W 1BXYA 5M19A 5JVHW 4YJMA 1RQVA 3GQ0A 3ZG0A 3G19A 3ZG5A 3J7ZZ 3I56W 4CPKA 1R6QC 5HL7W 5M1AA
chains in the Genus database with same CATH topology
1YHQW 1K73X 4IOAW 1Q81X 3CCJW 2ZJQW 1VQPW 1KC8X 5GAEa 2QA4W 3CF5W 4UY8Z 1VQKW 1M90X 2QEXW 1KQSV 3CXCV 1Q82X 3CCUW 1M1KX 3CC2W 5DM6W 3G6EW 3CMAW 1YI2W 1Q86X 1VQNW 4C1NA 1VQOW 3CMEW 5GAHa 3CCVW 1VQLW 1YJWW 4WF9W 3CCLW 4WFAW 4WFNW 3G4SW 4IO9W 3CC7W 1VQ7W 1YIJW 1K8AX 3OW2V 3CCMW 1YJ9W 3CD6W 5GADa 1N8RX 3I55W 1VQ5W 1QVFV 2ZJRW 1KD1X 3CCEW 1K9MX 2OTLW 1Q7YX 4U67W 1VQ9W 5GAGa 3CC4W 3DLLW 1YITW 1VQ4W 3CCSW 4WFBW 4WCEW 1S72W 1NJIX 3G71W 3PIPW 3CPWV 4IOCW 1YJNW 3PIOW 1QVGV 5DM7W 3CCRW 2ZJPW 1JJ2V 1VQ8W 5JVGW 3CCQW 1VQMW 2OTJW 1W2BV 1VQ6W 1BXYA 5JVHW 3J7ZZ 3I56W 5HL7W
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YHQ W;  1K73 X;  4IOA W;  1Q81 X;  3CCJ W;  2ZJQ W;  1VQP W;  1KC8 X;  5GAE a;  2QA4 W;  3CF5 W;  4UY8 Z;  1VQK W;  1M90 X;  2QEX W;  1KQS V;  3CXC V;  1Q82 X;  3CCU W;  1M1K X;  3CC2 W;  5DM6 W;  3G6E W;  3CMA W;  1YI2 W;  1Q86 X;  1VQN W;  1VQO W;  3CME W;  5GAH a;  3CCV W;  1VQL W;  1YJW W;  4WF9 W;  3CCL W;  4WFA W;  4WFN W;  3G4S W;  4IO9 W;  3CC7 W;  1VQ7 W;  1YIJ W;  1K8A X;  3OW2 V;  3CCM W;  1YJ9 W;  3CD6 W;  5GAD a;  1N8R X;  3I55 W;  1VQ5 W;  1QVF V;  2ZJR W;  1KD1 X;  3CCE W;  1K9M X;  2OTL W;  1Q7Y X;  4U67 W;  1VQ9 W;  5GAG a;  3CC4 W;  3DLL W;  1YIT W;  1VQ4 W;  3CCS W;  4WFB W;  4WCE W;  1S72 W;  1NJI X;  3G71 W;  3PIP W;  3CPW V;  4IOC W;  1YJN W;  3PIO W;  1QVG V;  5DM7 W;  3CCR W;  2ZJP W;  1JJ2 V;  1VQ8 W;  5JVG W;  3CCQ W;  1VQM W;  2OTJ W;  1W2B V;  1VQ6 W;  1BXY A;  5JVH W;  3J7Z Z;  3I56 W;  5HL7 W; 
#chains in the Genus database with same CATH topology
 1YHQ W;  1K73 X;  4IOA W;  1DD4 A;  1Q81 X;  1R6O C;  3CCJ W;  2ZJQ W;  3W7X A;  2W9R A;  1VQP W;  1KC8 X;  5GAE a;  1CTF A;  1MWS A;  2WA9 A;  2QA4 W;  3W7W A;  1MG9 A;  3CF5 W;  4UY8 Z;  1VQK W;  1M90 X;  4YJX A;  2QEX W;  1KQS V;  3CXC V;  1MBV B;  3O1F B;  1Q82 X;  3G1B A;  3CCU W;  1M1K X;  1MWR A;  3CC2 W;  5DM6 W;  3G6E W;  3CMA W;  1YI2 W;  1Q86 X;  1VQN W;  4C1N A;  1VQO W;  3CME W;  5GAH a;  3DNJ A;  3CCV W;  1VQL W;  1YJW W;  3ZFZ A;  3CCL W;  1MWU A;  3W7U A;  4WF9 W;  2WA8 A;  4WFA W;  4DKI A;  5M18 A;  4WFN W;  1MBX C;  3G4S W;  3GW1 A;  5CA3 A;  4IO9 W;  3CC7 W;  1VQ7 W;  1YIJ W;  1K8A X;  3OW2 V;  4CJN A;  3CCM W;  1YJ9 W;  3CD6 W;  5GAD a;  4BL3 A;  1N8R X;  3I55 W;  1VQ5 W;  1QVF V;  1DD3 A;  1LZW A;  2ZJR W;  1KD1 X;  4BL2 A;  3CCE W;  1K9M X;  1MBU C;  2OTL W;  3O2B A;  1Q7Y X;  4U67 W;  1MWT A;  3O2O A;  3D3I A;  3O1F A;  1VQ9 W;  1RQU A;  5GAG a;  3CC4 W;  3GQ1 A;  1YIT W;  3DLL W;  1VQ4 W;  3CCS W;  1VQQ A;  4WFB W;  4WCE W;  4YKA A;  1S72 W;  1NJI X;  3G71 W;  3G3P A;  5GW7 A;  3PIP W;  3CPW V;  3W7S A;  4IOC W;  1YJN W;  1RQS A;  3PIO W;  1QVG V;  5DM7 W;  3CCR W;  3W7T A;  2ZJP W;  1JJ2 V;  1VQ8 W;  5JVG W;  3CCQ W;  1VQM W;  2OTJ W;  3O2H A;  1W2B V;  1VQ6 W;  1BXY A;  5M19 A;  5JVH W;  4YJM A;  1RQV A;  3GQ0 A;  3ZG0 A;  3G19 A;  3ZG5 A;  3J7Z Z;  3I56 W;  4CPK A;  1R6Q C;  5HL7 W;  5M1A A; 
#chains in the Genus database with same CATH homology
 1YHQ W;  1K73 X;  4IOA W;  1Q81 X;  3CCJ W;  2ZJQ W;  1VQP W;  1KC8 X;  5GAE a;  2QA4 W;  3CF5 W;  4UY8 Z;  1VQK W;  1M90 X;  2QEX W;  1KQS V;  3CXC V;  1Q82 X;  3CCU W;  1M1K X;  3CC2 W;  5DM6 W;  3G6E W;  3CMA W;  1YI2 W;  1Q86 X;  1VQN W;  4C1N A;  1VQO W;  3CME W;  5GAH a;  3CCV W;  1VQL W;  1YJW W;  4WF9 W;  3CCL W;  4WFA W;  4WFN W;  3G4S W;  4IO9 W;  3CC7 W;  1VQ7 W;  1YIJ W;  1K8A X;  3OW2 V;  3CCM W;  1YJ9 W;  3CD6 W;  5GAD a;  1N8R X;  3I55 W;  1VQ5 W;  1QVF V;  2ZJR W;  1KD1 X;  3CCE W;  1K9M X;  2OTL W;  1Q7Y X;  4U67 W;  1VQ9 W;  5GAG a;  3CC4 W;  3DLL W;  1YIT W;  1VQ4 W;  3CCS W;  4WFB W;  4WCE W;  1S72 W;  1NJI X;  3G71 W;  3PIP W;  3CPW V;  4IOC W;  1YJN W;  3PIO W;  1QVG V;  5DM7 W;  3CCR W;  2ZJP W;  1JJ2 V;  1VQ8 W;  5JVG W;  3CCQ W;  1VQM W;  2OTJ W;  1W2B V;  1VQ6 W;  1BXY A;  5JVH W;  3J7Z Z;  3I56 W;  5HL7 W; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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