3CCSW

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2482a
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 46
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3ccsW02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 3ccsW01
3PIOW 4IO9W 3CPWV 1VQNW 4WCEW 1YJWW 4U67W 1YJNW 1YHQW 1KC8X 3I56W 1Q81X 3CD6W 4UY8Z 1VQPW 4WF9W 2OTLW 2ZJPW 3G6EW 1YITW 1JJ2V 3CMAW 2QA4W 1VQ7W 1YIJW 3CCSW 3DLLW 1S72W 5DM7W 1Q7YX 5JVGW 4WFAW 3CC2W 3CCQW 1K9MX 1VQ4W 1M90X 3CCVW 3OW2V 1Q82X 2ZJRW 4WFNW 1VQ9W 5GAEa 5GADa 1Q86X 1KD1X 1M1KX 4IOCW 2QEXW 3CXCV 5DM6W 3J7ZZ 1N8RX 1W2BV 4IOAW 1KQSV 3PIPW 3CC4W 3CC7W 1VQ5W 1VQKW 5HL7W 1K73X 3CCLW 3G4SW 5GAGa 1K8AX 1YI2W 4WFBW 5GAHa 3CMEW 3CCEW 1YJ9W 2ZJQW 3I55W 3CCUW 1VQ6W 1NJIX 1QVFV 3CCJW 1QVGV 1VQMW 1VQ8W 5JVHW 1BXYA 3CCMW 3CF5W 1VQLW 3CCRW 1VQOW 3G71W 2OTJW
chains in the Genus database with same CATH superfamily
3PIOW 3O2BA 4IO9W 3CPWV 1MWUA 4DKIA 1VQNW 4WCEW 4CJNA 1YJWW 4U67W 1YJNW 1YHQW 5M18A 1KC8X 3I56W 1Q81X 5GW7A 3CD6W 3GQ0A 4UY8Z 1VQPW 4WF9W 3ZG0A 2OTLW 2ZJPW 3G6EW 1YITW 3O2HA 5M19A 1MBVB 4BL2A 1JJ2V 3CMAW 2QA4W 1VQ7W 1YIJW 3CCSW 3DLLW 1MWRA 1S72W 5DM7W 3GQ1A 1RQUA 1RQSA 1Q7YX 4BL3A 5JVGW 4WFAW 3W7TA 3CC2W 3CCQW 1K9MX 1VQ4W 1M90X 4C1NA 1MWSA 3CCVW 3ZFZA 3OW2V 3W7WA 1Q82X 2ZJRW 4WFNW 1VQ9W 3G3PA 5GAEa 5GADa 1Q86X 1KD1X 1MG9A 1M1KX 4IOCW 2QEXW 3CXCV 5DM6W 3J7ZZ 3O1FB 1N8RX 1LZWA 1W2BV 4IOAW 1DD4A 1KQSV 3D3IA 3PIPW 3CC4W 3CC7W 1VQ5W 1R6OC 1VQKW 5HL7W 5CA3A 3GW1A 4YKAA 1K73X 3CCLW 3G4SW 2WA8A 5GAGa 3G19A 1K8AX 1YI2W 1CTFA 4WFBW 5GAHa 3CMEW 1VQQA 3CCEW 3ZG5A 3O2OA 4YJXA 1YJ9W 2ZJQW 3I55W 3CCUW 3O1FA 1VQ6W 1NJIX 1QVFV 4YJMA 3CCJW 1QVGV 5M1AA 1VQMW 1VQ8W 4CPKA 2WA9A 5JVHW 1BXYA 3CCMW 3DNJA 3CF5W 1RQVA 1MBXC 1VQLW 1DD3A 3CCRW 1MWTA 1VQOW 3G71W 2W9RA 2OTJW 1R6QC 3W7XA 3W7UA 1MBUC 3G1BA 3W7SA
chains in the Genus database with same CATH topology
3PIOW 4IO9W 3CPWV 1VQNW 4WCEW 1YJWW 4U67W 1YJNW 1YHQW 1KC8X 3I56W 1Q81X 3CD6W 4UY8Z 1VQPW 4WF9W 2OTLW 2ZJPW 3G6EW 1YITW 1JJ2V 3CMAW 2QA4W 1VQ7W 1YIJW 3CCSW 3DLLW 1S72W 5DM7W 1Q7YX 5JVGW 4WFAW 3CC2W 3CCQW 1K9MX 1VQ4W 1M90X 4C1NA 3CCVW 3OW2V 1Q82X 2ZJRW 4WFNW 1VQ9W 5GAEa 5GADa 1Q86X 1KD1X 1M1KX 4IOCW 2QEXW 3CXCV 5DM6W 3J7ZZ 1N8RX 1W2BV 4IOAW 1KQSV 3PIPW 3CC4W 3CC7W 1VQ5W 1VQKW 5HL7W 1K73X 3CCLW 3G4SW 5GAGa 1K8AX 1YI2W 4WFBW 5GAHa 3CMEW 3CCEW 1YJ9W 2ZJQW 3I55W 3CCUW 1VQ6W 1NJIX 1QVFV 3CCJW 1QVGV 1VQMW 1VQ8W 5JVHW 1BXYA 3CCMW 3CF5W 1VQLW 3CCRW 1VQOW 3G71W 2OTJW
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PIO W;  4IO9 W;  3CPW V;  1VQN W;  4WCE W;  1YJW W;  4U67 W;  1YJN W;  1YHQ W;  1KC8 X;  3I56 W;  1Q81 X;  3CD6 W;  4UY8 Z;  1VQP W;  4WF9 W;  2OTL W;  2ZJP W;  3G6E W;  1YIT W;  1JJ2 V;  3CMA W;  2QA4 W;  1VQ7 W;  1YIJ W;  3CCS W;  3DLL W;  1S72 W;  5DM7 W;  1Q7Y X;  5JVG W;  4WFA W;  3CC2 W;  3CCQ W;  1K9M X;  1VQ4 W;  1M90 X;  3CCV W;  3OW2 V;  1Q82 X;  2ZJR W;  4WFN W;  1VQ9 W;  5GAE a;  5GAD a;  1Q86 X;  1KD1 X;  1M1K X;  4IOC W;  2QEX W;  3CXC V;  5DM6 W;  3J7Z Z;  1N8R X;  1W2B V;  4IOA W;  1KQS V;  3PIP W;  3CC4 W;  3CC7 W;  1VQ5 W;  1VQK W;  5HL7 W;  1K73 X;  3CCL W;  3G4S W;  5GAG a;  1K8A X;  1YI2 W;  4WFB W;  5GAH a;  3CME W;  3CCE W;  1YJ9 W;  2ZJQ W;  3I55 W;  3CCU W;  1VQ6 W;  1NJI X;  1QVF V;  3CCJ W;  1QVG V;  1VQM W;  1VQ8 W;  5JVH W;  1BXY A;  3CCM W;  3CF5 W;  1VQL W;  3CCR W;  1VQO W;  3G71 W;  2OTJ W; 
#chains in the Genus database with same CATH topology
 3PIO W;  3O2B A;  4IO9 W;  3CPW V;  1MWU A;  4DKI A;  1VQN W;  4WCE W;  4CJN A;  1YJW W;  4U67 W;  1YJN W;  1YHQ W;  5M18 A;  1KC8 X;  3I56 W;  1Q81 X;  5GW7 A;  3CD6 W;  3GQ0 A;  4UY8 Z;  1VQP W;  4WF9 W;  3ZG0 A;  2OTL W;  2ZJP W;  3G6E W;  1YIT W;  3O2H A;  5M19 A;  1MBV B;  4BL2 A;  1JJ2 V;  3CMA W;  2QA4 W;  1VQ7 W;  1YIJ W;  3CCS W;  3DLL W;  1MWR A;  1S72 W;  5DM7 W;  3GQ1 A;  1RQU A;  1RQS A;  1Q7Y X;  4BL3 A;  5JVG W;  4WFA W;  3W7T A;  3CC2 W;  3CCQ W;  1K9M X;  1VQ4 W;  1M90 X;  4C1N A;  1MWS A;  3CCV W;  3ZFZ A;  3OW2 V;  3W7W A;  1Q82 X;  2ZJR W;  4WFN W;  1VQ9 W;  3G3P A;  5GAE a;  5GAD a;  1Q86 X;  1KD1 X;  1MG9 A;  1M1K X;  4IOC W;  2QEX W;  3CXC V;  5DM6 W;  3J7Z Z;  3O1F B;  1N8R X;  1LZW A;  1W2B V;  4IOA W;  1DD4 A;  1KQS V;  3D3I A;  3PIP W;  3CC4 W;  3CC7 W;  1VQ5 W;  1R6O C;  1VQK W;  5HL7 W;  5CA3 A;  3GW1 A;  4YKA A;  1K73 X;  3CCL W;  3G4S W;  2WA8 A;  5GAG a;  3G19 A;  1K8A X;  1YI2 W;  1CTF A;  4WFB W;  5GAH a;  3CME W;  1VQQ A;  3CCE W;  3ZG5 A;  3O2O A;  4YJX A;  1YJ9 W;  2ZJQ W;  3I55 W;  3CCU W;  3O1F A;  1VQ6 W;  1NJI X;  1QVF V;  4YJM A;  3CCJ W;  1QVG V;  5M1A A;  1VQM W;  1VQ8 W;  4CPK A;  2WA9 A;  5JVH W;  1BXY A;  3CCM W;  3DNJ A;  3CF5 W;  1RQV A;  1MBX C;  1VQL W;  1DD3 A;  3CCR W;  1MWT A;  1VQO W;  3G71 W;  2W9R A;  2OTJ W;  1R6Q C;  3W7X A;  3W7U A;  1MBU C;  3G1B A;  3W7S A; 
#chains in the Genus database with same CATH homology
 3PIO W;  4IO9 W;  3CPW V;  1VQN W;  4WCE W;  1YJW W;  4U67 W;  1YJN W;  1YHQ W;  1KC8 X;  3I56 W;  1Q81 X;  3CD6 W;  4UY8 Z;  1VQP W;  4WF9 W;  2OTL W;  2ZJP W;  3G6E W;  1YIT W;  1JJ2 V;  3CMA W;  2QA4 W;  1VQ7 W;  1YIJ W;  3CCS W;  3DLL W;  1S72 W;  5DM7 W;  1Q7Y X;  5JVG W;  4WFA W;  3CC2 W;  3CCQ W;  1K9M X;  1VQ4 W;  1M90 X;  4C1N A;  3CCV W;  3OW2 V;  1Q82 X;  2ZJR W;  4WFN W;  1VQ9 W;  5GAE a;  5GAD a;  1Q86 X;  1KD1 X;  1M1K X;  4IOC W;  2QEX W;  3CXC V;  5DM6 W;  3J7Z Z;  1N8R X;  1W2B V;  4IOA W;  1KQS V;  3PIP W;  3CC4 W;  3CC7 W;  1VQ5 W;  1VQK W;  5HL7 W;  1K73 X;  3CCL W;  3G4S W;  5GAG a;  1K8A X;  1YI2 W;  4WFB W;  5GAH a;  3CME W;  3CCE W;  1YJ9 W;  2ZJQ W;  3I55 W;  3CCU W;  1VQ6 W;  1NJI X;  1QVF V;  3CCJ W;  1QVG V;  1VQM W;  1VQ8 W;  5JVH W;  1BXY A;  3CCM W;  3CF5 W;  1VQL W;  3CCR W;  1VQO W;  3G71 W;  2OTJ W; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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