3CXCV

The structure of an enhanced oxazolidinone inhibitor bound to the 50s ribosomal subunit of h. marismortui
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design at the atomic level: design of biaryloxazolidinones as potent orally active antibiotics.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S RIBOSOMAL RNA
total genus 49
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-04-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
V PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3cxcV02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 3cxcV01
1QVGV 3CCRW 1VQNW 2OTJW 2QEXW 3CC4W 1KD1X 1KC8X 1S72W 4WFBW 3PIPW 1YJNW 3I55W 4IO9W 1YJWW 3I56W 1YHQW 5GAHa 4WCEW 1N8RX 1NJIX 3CCUW 3DLLW 3CPWV 5DM6W 1YJ9W 3CMEW 3CD6W 1VQ6W 3CCMW 3CF5W 1VQ4W 3OW2V 1VQKW 5GADa 3CCVW 3CCJW 1W2BV 1VQPW 3J7ZZ 2ZJRW 1VQOW 1K9MX 5JVHW 3CCQW 3CC7W 4WF9W 1QVFV 3G71W 3CCEW 3CCLW 4WFNW 3CCSW 3CMAW 2ZJQW 1KQSV 1Q81X 1Q86X 1K73X 4UY8Z 2OTLW 4U67W 1VQ5W 3G6EW 1BXYA 1VQLW 1VQ7W 1VQMW 1M1KX 3CXCV 1YI2W 4IOAW 2QA4W 1K8AX 5JVGW 2ZJPW 5HL7W 5DM7W 5GAEa 5GAGa 1M90X 3G4SW 1YITW 4IOCW 1VQ9W 4WFAW 1Q82X 1YIJW 3CC2W 1Q7YX 1JJ2V 1VQ8W 3PIOW
chains in the Genus database with same CATH superfamily
1QVGV 3CCRW 1VQNW 2OTJW 5M19A 2QEXW 3CC4W 1DD4A 1CTFA 1RQSA 3ZFZA 1KD1X 1KC8X 1S72W 4BL2A 4WFBW 3PIPW 1DD3A 4YKAA 1YJNW 3G3PA 3I55W 1MBXC 1MWSA 1VQQA 4IO9W 1YJWW 3O2HA 3I56W 1YHQW 5GAHa 4WCEW 1N8RX 5M18A 1NJIX 1R6QC 3CCUW 5GW7A 5CA3A 3DLLW 3CPWV 3O1FA 5DM6W 1YJ9W 4C1NA 1LZWA 1MWTA 5M1AA 3CMEW 3CD6W 1VQ6W 3CCMW 3CF5W 1VQ4W 1RQVA 1MBUC 1R6OC 3OW2V 2WA9A 3G19A 1VQKW 3G1BA 5GADa 4YJXA 3O2BA 3D3IA 3CCVW 3CCJW 3ZG5A 1W2BV 3W7UA 4CJNA 1VQPW 3J7ZZ 1MG9A 4BL3A 2ZJRW 1VQOW 1K9MX 5JVHW 3CCQW 3CC7W 3O2OA 3W7WA 4WF9W 1QVFV 2W9RA 3G71W 3CCEW 1MWRA 3CCLW 4WFNW 3CCSW 3CMAW 2ZJQW 1KQSV 3W7TA 1Q81X 1Q86X 1K73X 4UY8Z 2OTLW 4U67W 1VQ5W 3G6EW 2WA8A 1MWUA 1BXYA 3GW1A 1VQLW 1VQ7W 1VQMW 1M1KX 4YJMA 3CXCV 3W7SA 3GQ1A 1YI2W 4IOAW 2QA4W 1K8AX 5JVGW 1MBVB 3O1FB 2ZJPW 5HL7W 5DM7W 5GAEa 3DNJA 5GAGa 1M90X 3G4SW 1RQUA 1YITW 4IOCW 1VQ9W 4WFAW 3W7XA 1Q82X 3ZG0A 1YIJW 3CC2W 1Q7YX 1JJ2V 1VQ8W 4CPKA 3PIOW 3GQ0A 4DKIA
chains in the Genus database with same CATH topology
1QVGV 3CCRW 1VQNW 2OTJW 2QEXW 3CC4W 1KD1X 1KC8X 1S72W 4WFBW 3PIPW 1YJNW 3I55W 4IO9W 1YJWW 3I56W 1YHQW 5GAHa 4WCEW 1N8RX 1NJIX 3CCUW 3DLLW 3CPWV 5DM6W 1YJ9W 4C1NA 3CMEW 3CD6W 1VQ6W 3CCMW 3CF5W 1VQ4W 3OW2V 1VQKW 5GADa 3CCVW 3CCJW 1W2BV 1VQPW 3J7ZZ 2ZJRW 1VQOW 1K9MX 5JVHW 3CCQW 3CC7W 4WF9W 1QVFV 3G71W 3CCEW 3CCLW 4WFNW 3CCSW 3CMAW 2ZJQW 1KQSV 1Q81X 1Q86X 1K73X 4UY8Z 2OTLW 4U67W 1VQ5W 3G6EW 1BXYA 1VQLW 1VQ7W 1VQMW 1M1KX 3CXCV 1YI2W 4IOAW 2QA4W 1K8AX 5JVGW 2ZJPW 5HL7W 5DM7W 5GAEa 5GAGa 1M90X 3G4SW 1YITW 4IOCW 1VQ9W 4WFAW 1Q82X 1YIJW 3CC2W 1Q7YX 1JJ2V 1VQ8W 3PIOW
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QVG V;  3CCR W;  1VQN W;  2OTJ W;  2QEX W;  3CC4 W;  1KD1 X;  1KC8 X;  1S72 W;  4WFB W;  3PIP W;  1YJN W;  3I55 W;  4IO9 W;  1YJW W;  3I56 W;  1YHQ W;  5GAH a;  4WCE W;  1N8R X;  1NJI X;  3CCU W;  3DLL W;  3CPW V;  5DM6 W;  1YJ9 W;  3CME W;  3CD6 W;  1VQ6 W;  3CCM W;  3CF5 W;  1VQ4 W;  3OW2 V;  1VQK W;  5GAD a;  3CCV W;  3CCJ W;  1W2B V;  1VQP W;  3J7Z Z;  2ZJR W;  1VQO W;  1K9M X;  5JVH W;  3CCQ W;  3CC7 W;  4WF9 W;  1QVF V;  3G71 W;  3CCE W;  3CCL W;  4WFN W;  3CCS W;  3CMA W;  2ZJQ W;  1KQS V;  1Q81 X;  1Q86 X;  1K73 X;  4UY8 Z;  2OTL W;  4U67 W;  1VQ5 W;  3G6E W;  1BXY A;  1VQL W;  1VQ7 W;  1VQM W;  1M1K X;  3CXC V;  1YI2 W;  4IOA W;  2QA4 W;  1K8A X;  5JVG W;  2ZJP W;  5HL7 W;  5DM7 W;  5GAE a;  5GAG a;  1M90 X;  3G4S W;  1YIT W;  4IOC W;  1VQ9 W;  4WFA W;  1Q82 X;  1YIJ W;  3CC2 W;  1Q7Y X;  1JJ2 V;  1VQ8 W;  3PIO W; 
#chains in the Genus database with same CATH topology
 1QVG V;  3CCR W;  1VQN W;  2OTJ W;  5M19 A;  2QEX W;  3CC4 W;  1DD4 A;  1CTF A;  1RQS A;  3ZFZ A;  1KD1 X;  1KC8 X;  1S72 W;  4BL2 A;  4WFB W;  3PIP W;  1DD3 A;  4YKA A;  1YJN W;  3G3P A;  3I55 W;  1MBX C;  1MWS A;  1VQQ A;  4IO9 W;  1YJW W;  3O2H A;  3I56 W;  1YHQ W;  5GAH a;  4WCE W;  1N8R X;  5M18 A;  1NJI X;  1R6Q C;  3CCU W;  5GW7 A;  5CA3 A;  3DLL W;  3CPW V;  3O1F A;  5DM6 W;  1YJ9 W;  4C1N A;  1LZW A;  1MWT A;  5M1A A;  3CME W;  3CD6 W;  1VQ6 W;  3CCM W;  3CF5 W;  1VQ4 W;  1RQV A;  1MBU C;  1R6O C;  3OW2 V;  2WA9 A;  3G19 A;  1VQK W;  3G1B A;  5GAD a;  4YJX A;  3O2B A;  3D3I A;  3CCV W;  3CCJ W;  3ZG5 A;  1W2B V;  3W7U A;  4CJN A;  1VQP W;  3J7Z Z;  1MG9 A;  4BL3 A;  2ZJR W;  1VQO W;  1K9M X;  5JVH W;  3CCQ W;  3CC7 W;  3O2O A;  3W7W A;  4WF9 W;  1QVF V;  2W9R A;  3G71 W;  3CCE W;  1MWR A;  3CCL W;  4WFN W;  3CCS W;  3CMA W;  2ZJQ W;  1KQS V;  3W7T A;  1Q81 X;  1Q86 X;  1K73 X;  4UY8 Z;  2OTL W;  4U67 W;  1VQ5 W;  3G6E W;  2WA8 A;  1MWU A;  1BXY A;  3GW1 A;  1VQL W;  1VQ7 W;  1VQM W;  1M1K X;  4YJM A;  3CXC V;  3W7S A;  3GQ1 A;  1YI2 W;  4IOA W;  2QA4 W;  1K8A X;  5JVG W;  1MBV B;  3O1F B;  2ZJP W;  5HL7 W;  5DM7 W;  5GAE a;  3DNJ A;  5GAG a;  1M90 X;  3G4S W;  1RQU A;  1YIT W;  4IOC W;  1VQ9 W;  4WFA W;  3W7X A;  1Q82 X;  3ZG0 A;  1YIJ W;  3CC2 W;  1Q7Y X;  1JJ2 V;  1VQ8 W;  4CPK A;  3PIO W;  3GQ0 A;  4DKI A; 
#chains in the Genus database with same CATH homology
 1QVG V;  3CCR W;  1VQN W;  2OTJ W;  2QEX W;  3CC4 W;  1KD1 X;  1KC8 X;  1S72 W;  4WFB W;  3PIP W;  1YJN W;  3I55 W;  4IO9 W;  1YJW W;  3I56 W;  1YHQ W;  5GAH a;  4WCE W;  1N8R X;  1NJI X;  3CCU W;  3DLL W;  3CPW V;  5DM6 W;  1YJ9 W;  4C1N A;  3CME W;  3CD6 W;  1VQ6 W;  3CCM W;  3CF5 W;  1VQ4 W;  3OW2 V;  1VQK W;  5GAD a;  3CCV W;  3CCJ W;  1W2B V;  1VQP W;  3J7Z Z;  2ZJR W;  1VQO W;  1K9M X;  5JVH W;  3CCQ W;  3CC7 W;  4WF9 W;  1QVF V;  3G71 W;  3CCE W;  3CCL W;  4WFN W;  3CCS W;  3CMA W;  2ZJQ W;  1KQS V;  1Q81 X;  1Q86 X;  1K73 X;  4UY8 Z;  2OTL W;  4U67 W;  1VQ5 W;  3G6E W;  1BXY A;  1VQL W;  1VQ7 W;  1VQM W;  1M1K X;  3CXC V;  1YI2 W;  4IOA W;  2QA4 W;  1K8A X;  5JVG W;  2ZJP W;  5HL7 W;  5DM7 W;  5GAE a;  5GAG a;  1M90 X;  3G4S W;  1YIT W;  4IOC W;  1VQ9 W;  4WFA W;  1Q82 X;  1YIJ W;  3CC2 W;  1Q7Y X;  1JJ2 V;  1VQ8 W;  3PIO W; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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