3CXCV

The structure of an enhanced oxazolidinone inhibitor bound to the 50s ribosomal subunit of h. marismortui
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ribosome
publication title Design at the atomic level: design of biaryloxazolidinones as potent orally active antibiotics.
pubmed doi rcsb
molecule keywords 23S RIBOSOMAL RNA
total genus 49
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-04-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
V PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3cxcV02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 3cxcV01
1YJWW 4WF9W 2OTJW 4WFNW 1YJNW 5DM7W 1QVFV 3CC4W 3CCQW 3I55W 3CC2W 3CCMW 1VQ8W 3PIOW 1Q86X 3CMEW 3CMAW 5HL7W 1S72W 1YJ9W 2ZJPW 1W2BV 3G6EW 5GAHa 1KD1X 1VQ7W 1Q7YX 3CCSW 3CCLW 3I56W 1VQMW 3CXCV 1KQSV 1QVGV 4WFAW 5DM6W 2ZJQW 4IOAW 3CCEW 3J7ZZ 1VQ5W 3CCUW 1YI2W 1M1KX 3G4SW 4UY8Z 3CC7W 3CD6W 2OTLW 5GADa 1VQKW 1YIJW 4U67W 3CCVW 1VQ4W 1N8RX 1YITW 1K8AX 1Q81X 4WCEW 3DLLW 1KC8X 3CCJW 1NJIX 2QA4W 5JVHW 1M90X 1VQOW 3PIPW 4IOCW 1BXYA 5JVGW 1JJ2V 1VQLW 1VQ6W 3CPWV 5GAEa 5GAGa 1Q82X 4IO9W 3OW2V 1K73X 2QEXW 1YHQW 3CCRW 1VQ9W 3G71W 3CF5W 1K9MX 4WFBW 1VQPW 1VQNW 2ZJRW
chains in the Genus database with same CATH superfamily
1YJWW 5CA3A 3W7XA 4WF9W 3G3PA 2OTJW 1CTFA 4WFNW 1YJNW 3W7SA 5DM7W 1QVFV 1DD3A 2WA8A 3CC4W 3CCQW 3DNJA 3I55W 3CC2W 3CCMW 1VQ8W 3ZG0A 4CJNA 5M19A 1RQUA 3PIOW 3ZG5A 5M18A 1Q86X 3CMEW 3G1BA 3CMAW 1DD4A 5HL7W 1S72W 4CPKA 1YJ9W 2ZJPW 1W2BV 3G6EW 5GAHa 1KD1X 1VQ7W 4YJXA 1Q7YX 1R6OC 1RQSA 3CCSW 3CCLW 3I56W 3O2BA 1VQMW 4YKAA 1VQQA 3CXCV 1KQSV 1QVGV 3G19A 4WFAW 5DM6W 2ZJQW 4IOAW 3O2OA 4C1NA 3CCEW 3GW1A 3O1FA 3J7ZZ 1VQ5W 3CCUW 1MWSA 1YI2W 4BL3A 1M1KX 3G4SW 4UY8Z 3CC7W 3CD6W 4DKIA 2OTLW 2W9RA 5GADa 1VQKW 1MBVB 4YJMA 1YIJW 4U67W 3CCVW 4BL2A 1VQ4W 1N8RX 1MBXC 1MWRA 1YITW 5M1AA 3W7UA 1K8AX 1MWUA 1Q81X 1LZWA 1MG9A 4WCEW 1MBUC 3DLLW 1KC8X 3CCJW 5GW7A 1NJIX 3O1FB 2QA4W 5JVHW 1M90X 3GQ1A 1VQOW 1R6QC 3PIPW 4IOCW 1BXYA 5JVGW 3D3IA 1JJ2V 1MWTA 3ZFZA 3W7TA 2WA9A 1VQLW 1VQ6W 3W7WA 3CPWV 5GAEa 5GAGa 3GQ0A 1RQVA 1Q82X 4IO9W 3OW2V 1K73X 2QEXW 1YHQW 3CCRW 1VQ9W 3G71W 3CF5W 1K9MX 4WFBW 1VQPW 3O2HA 1VQNW 2ZJRW
chains in the Genus database with same CATH topology
1YJWW 4WF9W 2OTJW 4WFNW 1YJNW 5DM7W 1QVFV 3CC4W 3CCQW 3I55W 3CC2W 3CCMW 1VQ8W 3PIOW 1Q86X 3CMEW 3CMAW 5HL7W 1S72W 1YJ9W 2ZJPW 1W2BV 3G6EW 5GAHa 1KD1X 1VQ7W 1Q7YX 3CCSW 3CCLW 3I56W 1VQMW 3CXCV 1KQSV 1QVGV 4WFAW 5DM6W 2ZJQW 4IOAW 4C1NA 3CCEW 3J7ZZ 1VQ5W 3CCUW 1YI2W 1M1KX 3G4SW 4UY8Z 3CC7W 3CD6W 2OTLW 5GADa 1VQKW 1YIJW 4U67W 3CCVW 1VQ4W 1N8RX 1YITW 1K8AX 1Q81X 4WCEW 3DLLW 1KC8X 3CCJW 1NJIX 2QA4W 5JVHW 1M90X 1VQOW 3PIPW 4IOCW 1BXYA 5JVGW 1JJ2V 1VQLW 1VQ6W 3CPWV 5GAEa 5GAGa 1Q82X 4IO9W 3OW2V 1K73X 2QEXW 1YHQW 3CCRW 1VQ9W 3G71W 3CF5W 1K9MX 4WFBW 1VQPW 1VQNW 2ZJRW
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YJW W;  4WF9 W;  2OTJ W;  4WFN W;  1YJN W;  5DM7 W;  1QVF V;  3CC4 W;  3CCQ W;  3I55 W;  3CC2 W;  3CCM W;  1VQ8 W;  3PIO W;  1Q86 X;  3CME W;  3CMA W;  5HL7 W;  1S72 W;  1YJ9 W;  2ZJP W;  1W2B V;  3G6E W;  5GAH a;  1KD1 X;  1VQ7 W;  1Q7Y X;  3CCS W;  3CCL W;  3I56 W;  1VQM W;  3CXC V;  1KQS V;  1QVG V;  4WFA W;  5DM6 W;  2ZJQ W;  4IOA W;  3CCE W;  3J7Z Z;  1VQ5 W;  3CCU W;  1YI2 W;  1M1K X;  3G4S W;  4UY8 Z;  3CC7 W;  3CD6 W;  2OTL W;  5GAD a;  1VQK W;  1YIJ W;  4U67 W;  3CCV W;  1VQ4 W;  1N8R X;  1YIT W;  1K8A X;  1Q81 X;  4WCE W;  3DLL W;  1KC8 X;  3CCJ W;  1NJI X;  2QA4 W;  5JVH W;  1M90 X;  1VQO W;  3PIP W;  4IOC W;  1BXY A;  5JVG W;  1JJ2 V;  1VQL W;  1VQ6 W;  3CPW V;  5GAE a;  5GAG a;  1Q82 X;  4IO9 W;  3OW2 V;  1K73 X;  2QEX W;  1YHQ W;  3CCR W;  1VQ9 W;  3G71 W;  3CF5 W;  1K9M X;  4WFB W;  1VQP W;  1VQN W;  2ZJR W; 
#chains in the Genus database with same CATH topology
 1YJW W;  5CA3 A;  3W7X A;  4WF9 W;  3G3P A;  2OTJ W;  1CTF A;  4WFN W;  1YJN W;  3W7S A;  5DM7 W;  1QVF V;  1DD3 A;  2WA8 A;  3CC4 W;  3CCQ W;  3DNJ A;  3I55 W;  3CC2 W;  3CCM W;  1VQ8 W;  3ZG0 A;  4CJN A;  5M19 A;  1RQU A;  3PIO W;  3ZG5 A;  5M18 A;  1Q86 X;  3CME W;  3G1B A;  3CMA W;  1DD4 A;  5HL7 W;  1S72 W;  4CPK A;  1YJ9 W;  2ZJP W;  1W2B V;  3G6E W;  5GAH a;  1KD1 X;  1VQ7 W;  4YJX A;  1Q7Y X;  1R6O C;  1RQS A;  3CCS W;  3CCL W;  3I56 W;  3O2B A;  1VQM W;  4YKA A;  1VQQ A;  3CXC V;  1KQS V;  1QVG V;  3G19 A;  4WFA W;  5DM6 W;  2ZJQ W;  4IOA W;  3O2O A;  4C1N A;  3CCE W;  3GW1 A;  3O1F A;  3J7Z Z;  1VQ5 W;  3CCU W;  1MWS A;  1YI2 W;  4BL3 A;  1M1K X;  3G4S W;  4UY8 Z;  3CC7 W;  3CD6 W;  4DKI A;  2OTL W;  2W9R A;  5GAD a;  1VQK W;  1MBV B;  4YJM A;  1YIJ W;  4U67 W;  3CCV W;  4BL2 A;  1VQ4 W;  1N8R X;  1MBX C;  1MWR A;  1YIT W;  5M1A A;  3W7U A;  1K8A X;  1MWU A;  1Q81 X;  1LZW A;  1MG9 A;  4WCE W;  1MBU C;  3DLL W;  1KC8 X;  3CCJ W;  5GW7 A;  1NJI X;  3O1F B;  2QA4 W;  5JVH W;  1M90 X;  3GQ1 A;  1VQO W;  1R6Q C;  3PIP W;  4IOC W;  1BXY A;  5JVG W;  3D3I A;  1JJ2 V;  1MWT A;  3ZFZ A;  3W7T A;  2WA9 A;  1VQL W;  1VQ6 W;  3W7W A;  3CPW V;  5GAE a;  5GAG a;  3GQ0 A;  1RQV A;  1Q82 X;  4IO9 W;  3OW2 V;  1K73 X;  2QEX W;  1YHQ W;  3CCR W;  1VQ9 W;  3G71 W;  3CF5 W;  1K9M X;  4WFB W;  1VQP W;  3O2H A;  1VQN W;  2ZJR W; 
#chains in the Genus database with same CATH homology
 1YJW W;  4WF9 W;  2OTJ W;  4WFN W;  1YJN W;  5DM7 W;  1QVF V;  3CC4 W;  3CCQ W;  3I55 W;  3CC2 W;  3CCM W;  1VQ8 W;  3PIO W;  1Q86 X;  3CME W;  3CMA W;  5HL7 W;  1S72 W;  1YJ9 W;  2ZJP W;  1W2B V;  3G6E W;  5GAH a;  1KD1 X;  1VQ7 W;  1Q7Y X;  3CCS W;  3CCL W;  3I56 W;  1VQM W;  3CXC V;  1KQS V;  1QVG V;  4WFA W;  5DM6 W;  2ZJQ W;  4IOA W;  4C1N A;  3CCE W;  3J7Z Z;  1VQ5 W;  3CCU W;  1YI2 W;  1M1K X;  3G4S W;  4UY8 Z;  3CC7 W;  3CD6 W;  2OTL W;  5GAD a;  1VQK W;  1YIJ W;  4U67 W;  3CCV W;  1VQ4 W;  1N8R X;  1YIT W;  1K8A X;  1Q81 X;  4WCE W;  3DLL W;  1KC8 X;  3CCJ W;  1NJI X;  2QA4 W;  5JVH W;  1M90 X;  1VQO W;  3PIP W;  4IOC W;  1BXY A;  5JVG W;  1JJ2 V;  1VQL W;  1VQ6 W;  3CPW V;  5GAE a;  5GAG a;  1Q82 X;  4IO9 W;  3OW2 V;  1K73 X;  2QEX W;  1YHQ W;  3CCR W;  1VQ9 W;  3G71 W;  3CF5 W;  1K9M X;  4WFB W;  1VQP W;  1VQN W;  2ZJR W; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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