3E6Y | Genus

Total Genus 101

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	101
sequence length	234
structure length	234
Chain Sequence	PTAREENVYMAKLAEQAERYEEMVEFMEKVSNSLGSEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRGNEEHVNSIREYRSKIENELSKICDGILKLLDAKLIPSAASGDSKVFYLKMKGDYHRYLAEFKTGAERKEAAESTLTAYKAAQDIATTELAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFDEAIAELDTLGEESYKDSTLIMQLLRDNLTLWT

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	A structural rationale for selective stabilization of anti-tumor interactions of 14-3-3 proteins by cotylenin A pubmed rcsb
molecule keywords	14-3-3-like protein C
molecule tags	Signaling protein
source organism	Nicotiana tabacum
total genus	101
structure length	234
sequence length	234
chains with identical sequence	B
ec nomenclature
pdb deposition date	2008-08-17

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00244	14-3-3	14-3-3 protein

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.190.20	Mainly Alpha	Up-down Bundle	Delta-Endotoxin; domain 1	14-3-3 domain	3e6yA00

3O8IA 4Y3BA 1O9FA 4DX0A 3T0LA 4DHMA 4IEAA 4O46A 4JC3A 3P1PA 4FL5A 3UX0A 3IQVA 4J6SA 1O9DA 3SMKA 4DHPA 3NKXA 3P1QA 4IHLA 4HKCA 3RDHA 1YZ5A 3UALA 4F7RA 1A37A 3SMOA 2V7DA 5LU1A 2WH0A 4WRQA 3UBWA 4ZQ0A 3UZDA 2B05A 5LU2A 4N7YA 5HF3A 2BTPA 3M50A 4QLIA 4N84A 4Y32A 3EFZA 1A4OA 2C74A 5BTVA 2C23A 4Y5IA 3LW1A 3U9XA 3AXYC 4FJ3A 4ZDRA 4JDDA 5IQPA 3IQUA 3T0MA 4DHQA 5D3EA 4BG6A 3M51A 5LVZA 3P1NA 4DHRA 4DHTA 2NPMA 1YWTA 1IB1A 2C63A 2BR9A 3SP5A 4FR3A 4DHNA 4GNTA 3IQJA 5LHOA 3MHRA 4N7GA 2O02A 3CU8A 5D3FA 5EXAA 4DATA 2C1NA 2O98A 4DHOA 5EWZA 5D2DA 3SMMA 1QJAA 1O9EA 4DNKA 5LX2A 1A38A 4DAUA 4E2EA 5BY9A 1O9CA 2O8PA 4DHUA 5J31A 4DHSA 3SMNA 3SMLA 2C1JA 3E6YA 3P1SA 2BQ0A 1QJBA 3P1OA 3P1RA 5F74A 3SPRA
chains in the Genus database with same CATH superfamily

1URJA 3O8IA 4QX1A 4QX3A 4Y3BA 1O9FA 4DX0A 3T0LA 4DHMA 4IEAA 4O46A 4JC3A 3P1PA 4QX2A 4FL5A 3UX0A 3IQVA 4J6SA 1JI6A 4D8MA 1O9DA 3SMKA 4DHPA 3NKXA 1DLCA 3P1QA 4IHLA 4HKCA 1YZ5A 3RDHA 3UALA 4F7RA 1A37A 4W8JA 3SMOA 2V7DA 5LU1A 2WH0A 4WRQA 3UBWA 4ZQ0A 3UZDA 2B05A 5LU2A 4N7YA 5HF3A 2BTPA 3M50A 4QLIA 4N84A 4Y32A 3X0UA 3EFZA 1A4OA 2C74A 5BTVA 3CQCA 2C23A 4Y5IA 3LW1A 3U9XA 3AXYC 4FJ3A 4ZDRA 4JDDA 5IQPA 3IQUA 3T0MA 4DHQA 5D3EA 4BG6A 3M51A 5LVZA 3P1NA 4DHRA 4DHTA 2NPMA 1YWTA 1IB1A 2C63A 3CQGA 3I4RA 2C9KA 2BR9A 3SP5A 4FR3A 4DHNA 4GNTA 3IQJA 5LHOA 3MHRA 4N7GA 2O02A 3CU8A 5D3FA 5EXAA 4DATA 2C1NA 2O98A 4DHOA 1W99A 5EWZA 3ZHEB 4ARXA 5D2DA 3SMMA 1QJAA 1O9EA 4DNKA 1I5PA 5LX2A 1A38A 4QX0A 4DAUA 4E2EA 5BY9A 1CIYA 1O9CA 2O8PA 4ARYA 4DHUA 5J31A 4DHSA 3SMNA 3SMLA 2C1JA 1S2XA 3E6YA 3P1SA 2BQ0A 1QJBA 3P1OA 3P1RA 5F74A 3EB7A 3SPRA 4MOAA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3O8I A;  4Y3B A;  1O9F A;  4DX0 A;  3T0L A;  4DHM A;  4IEA A;  4O46 A;  4JC3 A;  3P1P A;  4FL5 A;  3UX0 A;  3IQV A;  4J6S A;  1O9D A;  3SMK A;  4DHP A;  3NKX A;  3P1Q A;  4IHL A;  4HKC A;  3RDH A;  1YZ5 A;  3UAL A;  4F7R A;  1A37 A;  3SMO A;  2V7D A;  5LU1 A;  2WH0 A;  4WRQ A;  3UBW A;  4ZQ0 A;  3UZD A;  2B05 A;  5LU2 A;  4N7Y A;  5HF3 A;  2BTP A;  3M50 A;  4QLI A;  4N84 A;  4Y32 A;  3EFZ A;  1A4O A;  2C74 A;  5BTV A;  2C23 A;  4Y5I A;  3LW1 A;  3U9X A;  3AXY C;  4FJ3 A;  4ZDR A;  4JDD A;  5IQP A;  3IQU A;  3T0M A;  4DHQ A;  5D3E A;  4BG6 A;  3M51 A;  5LVZ A;  3P1N A;  4DHR A;  4DHT A;  2NPM A;  1YWT A;  1IB1 A;  2C63 A;  2BR9 A;  3SP5 A;  4FR3 A;  4DHN A;  4GNT A;  3IQJ A;  5LHO A;  3MHR A;  4N7G A;  2O02 A;  3CU8 A;  5D3F A;  5EXA A;  4DAT A;  2C1N A;  2O98 A;  4DHO A;  5EWZ A;  5D2D A;  3SMM A;  1QJA A;  1O9E A;  4DNK A;  5LX2 A;  1A38 A;  4DAU A;  4E2E A;  5BY9 A;  1O9C A;  2O8P A;  4DHU A;  5J31 A;  4DHS A;  3SMN A;  3SML A;  2C1J A;  3E6Y A;  3P1S A;  2BQ0 A;  1QJB A;  3P1O A;  3P1R A;  5F74 A;  3SPR A; 
#chains in the Genus database with same CATH topology
 1URJ A;  3O8I A;  4QX1 A;  4QX3 A;  4Y3B A;  1O9F A;  4DX0 A;  3T0L A;  4DHM A;  4IEA A;  4O46 A;  4JC3 A;  3P1P A;  4QX2 A;  4FL5 A;  3UX0 A;  3IQV A;  4J6S A;  1JI6 A;  4D8M A;  1O9D A;  3SMK A;  4DHP A;  3NKX A;  1DLC A;  3P1Q A;  4IHL A;  4HKC A;  1YZ5 A;  3RDH A;  3UAL A;  4F7R A;  1A37 A;  4W8J A;  3SMO A;  2V7D A;  5LU1 A;  2WH0 A;  4WRQ A;  3UBW A;  4ZQ0 A;  3UZD A;  2B05 A;  5LU2 A;  4N7Y A;  5HF3 A;  2BTP A;  3M50 A;  4QLI A;  4N84 A;  4Y32 A;  3X0U A;  3EFZ A;  1A4O A;  2C74 A;  5BTV A;  3CQC A;  2C23 A;  4Y5I A;  3LW1 A;  3U9X A;  3AXY C;  4FJ3 A;  4ZDR A;  4JDD A;  5IQP A;  3IQU A;  3T0M A;  4DHQ A;  5D3E A;  4BG6 A;  3M51 A;  5LVZ A;  3P1N A;  4DHR A;  4DHT A;  2NPM A;  1YWT A;  1IB1 A;  2C63 A;  3CQG A;  3I4R A;  2C9K A;  2BR9 A;  3SP5 A;  4FR3 A;  4DHN A;  4GNT A;  3IQJ A;  5LHO A;  3MHR A;  4N7G A;  2O02 A;  3CU8 A;  5D3F A;  5EXA A;  4DAT A;  2C1N A;  2O98 A;  4DHO A;  1W99 A;  5EWZ A;  3ZHE B;  4ARX A;  5D2D A;  3SMM A;  1QJA A;  1O9E A;  4DNK A;  1I5P A;  5LX2 A;  1A38 A;  4QX0 A;  4DAU A;  4E2E A;  5BY9 A;  1CIY A;  1O9C A;  2O8P A;  4ARY A;  4DHU A;  5J31 A;  4DHS A;  3SMN A;  3SML A;  2C1J A;  1S2X A;  3E6Y A;  3P1S A;  2BQ0 A;  1QJB A;  3P1O A;  3P1R A;  5F74 A;  3EB7 A;  3SPR A;  4MOA A; 
#chains in the Genus database with same CATH homology
 3O8I A;  4Y3B A;  1O9F A;  4DX0 A;  3T0L A;  4DHM A;  4IEA A;  4O46 A;  4JC3 A;  3P1P A;  4FL5 A;  3UX0 A;  3IQV A;  4J6S A;  1O9D A;  3SMK A;  4DHP A;  3NKX A;  3P1Q A;  4IHL A;  4HKC A;  3RDH A;  1YZ5 A;  3UAL A;  4F7R A;  1A37 A;  3SMO A;  2V7D A;  5LU1 A;  2WH0 A;  4WRQ A;  3UBW A;  4ZQ0 A;  3UZD A;  2B05 A;  5LU2 A;  4N7Y A;  5HF3 A;  2BTP A;  3M50 A;  4QLI A;  4N84 A;  4Y32 A;  3EFZ A;  1A4O A;  2C74 A;  5BTV A;  2C23 A;  4Y5I A;  3LW1 A;  3U9X A;  3AXY C;  4FJ3 A;  4ZDR A;  4JDD A;  5IQP A;  3IQU A;  3T0M A;  4DHQ A;  5D3E A;  4BG6 A;  3M51 A;  5LVZ A;  3P1N A;  4DHR A;  4DHT A;  2NPM A;  1YWT A;  1IB1 A;  2C63 A;  2BR9 A;  3SP5 A;  4FR3 A;  4DHN A;  4GNT A;  3IQJ A;  5LHO A;  3MHR A;  4N7G A;  2O02 A;  3CU8 A;  5D3F A;  5EXA A;  4DAT A;  2C1N A;  2O98 A;  4DHO A;  5EWZ A;  5D2D A;  3SMM A;  1QJA A;  1O9E A;  4DNK A;  5LX2 A;  1A38 A;  4DAU A;  4E2E A;  5BY9 A;  1O9C A;  2O8P A;  4DHU A;  5J31 A;  4DHS A;  3SMN A;  3SML A;  2C1J A;  3E6Y A;  3P1S A;  2BQ0 A;  1QJB A;  3P1O A;  3P1R A;  5F74 A;  3SPR A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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3E6YA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations