3LW1 | Genus

Total Genus 103

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	103
sequence length	236
structure length	234
Chain Sequence	GAMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Peptide binding protein
source organism	Homo sapiens
publication title	Structure of the p53 C-terminus bound to 14-3-3: Implications for stabilization of the p53 tetramer pubmed doi rcsb
molecule keywords	14-3-3 protein sigma
total genus	103
structure length	234
sequence length	236
ec nomenclature
pdb deposition date	2010-02-23

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00244	14-3-3	14-3-3 protein

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.190.20	Mainly Alpha	Up-down Bundle	Delta-Endotoxin; domain 1	14-3-3 domain	3lw1A00

4DHSA 1IB1A 5HF3A 3U9XA 3P1OA 3E6YA 1O9DA 5IQPA 3P1NA 3AXYC 2B05A 5D3FA 3P1QA 4N7GA 3MHRA 1YWTA 3P1SA 3UBWA 5LU2A 5BY9A 5LU1A 4GNTA 4O46A 3LW1A 3P1PA 1A4OA 3SMLA 4IHLA 5EWZA 4DHQA 5LVZA 4N7YA 2C74A 4FJ3A 3SMKA 4FL5A 3T0MA 5LHOA 4E2EA 1QJAA 2C63A 4DAUA 4DNKA 4IEAA 3SMMA 3UX0A 3M50A 3SPRA 5F74A 2C1NA 4F7RA 4BG6A 1O9EA 5LX2A 2O02A 1O9CA 4HKCA 2BQ0A 3SMNA 3SMOA 4DHOA 4DHUA 3IQVA 4QLIA 4Y32A 5D3EA 4Y3BA 4DHNA 3CU8A 4FR3A 1A37A 2BR9A 4DHPA 3NKXA 5EXAA 4DHRA 4DHTA 1YZ5A 2C1JA 3EFZA 4J6SA 2C23A 4N84A 2BTPA 2WH0A 2NPMA 3O8IA 2O8PA 2V7DA 3IQUA 2O98A 3UZDA 3P1RA 4DX0A 4JDDA 4WRQA 4JC3A 4Y5IA 4DATA 3RDHA 5BTVA 3T0LA 1QJBA 5D2DA 4ZDRA 5J31A 1A38A 3IQJA 1O9FA 3M51A 3UALA 4ZQ0A 4DHMA 3SP5A
chains in the Genus database with same CATH superfamily

4DHSA 1IB1A 5HF3A 3U9XA 3P1OA 3E6YA 1O9DA 1I5PA 5IQPA 1S2XA 3P1NA 3AXYC 2B05A 5D3FA 3P1QA 4N7GA 3MHRA 1YWTA 3P1SA 4W8JA 3UBWA 1W99A 5LU2A 5BY9A 5LU1A 4GNTA 4O46A 3LW1A 3P1PA 1A4OA 3SMLA 4IHLA 5EWZA 3X0UA 4DHQA 4N7YA 5LVZA 2C74A 4FJ3A 3SMKA 4FL5A 3T0MA 5LHOA 4E2EA 1QJAA 2C63A 4DAUA 1CIYA 3EB7A 4DNKA 4IEAA 4ZQ0A 3SMMA 3I4RA 3UX0A 3M50A 3SPRA 5F74A 2C1NA 2C9KA 4F7RA 3ZHEB 4BG6A 4ARYA 1O9EA 5LX2A 2O02A 1O9CA 4QX0A 4HKCA 2BQ0A 3SMNA 3SMOA 4DHOA 4DHUA 3IQVA 4QX2A 4QLIA 4Y32A 5D3EA 4Y3BA 4DHNA 3CU8A 4FR3A 1A37A 2BR9A 4DHPA 3NKXA 5EXAA 4D8MA 3CQGA 4DHRA 3CQCA 4DHTA 1YZ5A 2C1JA 3EFZA 1JI6A 4J6SA 2C23A 4N84A 2BTPA 2WH0A 2NPMA 4QX1A 3O8IA 2V7DA 3IQUA 2O98A 3UZDA 3P1RA 4DX0A 4JDDA 4MOAA 4WRQA 4JC3A 4Y5IA 4DATA 3RDHA 5BTVA 4ARXA 3T0LA 4QX3A 1QJBA 1DLCA 5D2DA 4ZDRA 5J31A 1A38A 3IQJA 1O9FA 3M51A 3UALA 1URJA 2O8PA 4DHMA 3SP5A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4DHS A;  1IB1 A;  5HF3 A;  3U9X A;  3P1O A;  3E6Y A;  1O9D A;  5IQP A;  3P1N A;  3AXY C;  2B05 A;  5D3F A;  3P1Q A;  4N7G A;  3MHR A;  1YWT A;  3P1S A;  3UBW A;  5LU2 A;  5BY9 A;  5LU1 A;  4GNT A;  4O46 A;  3LW1 A;  3P1P A;  1A4O A;  3SML A;  4IHL A;  5EWZ A;  4DHQ A;  5LVZ A;  4N7Y A;  2C74 A;  4FJ3 A;  3SMK A;  4FL5 A;  3T0M A;  5LHO A;  4E2E A;  1QJA A;  2C63 A;  4DAU A;  4DNK A;  4IEA A;  3SMM A;  3UX0 A;  3M50 A;  3SPR A;  5F74 A;  2C1N A;  4F7R A;  4BG6 A;  1O9E A;  5LX2 A;  2O02 A;  1O9C A;  4HKC A;  2BQ0 A;  3SMN A;  3SMO A;  4DHO A;  4DHU A;  3IQV A;  4QLI A;  4Y32 A;  5D3E A;  4Y3B A;  4DHN A;  3CU8 A;  4FR3 A;  1A37 A;  2BR9 A;  4DHP A;  3NKX A;  5EXA A;  4DHR A;  4DHT A;  1YZ5 A;  2C1J A;  3EFZ A;  4J6S A;  2C23 A;  4N84 A;  2BTP A;  2WH0 A;  2NPM A;  3O8I A;  2O8P A;  2V7D A;  3IQU A;  2O98 A;  3UZD A;  3P1R A;  4DX0 A;  4JDD A;  4WRQ A;  4JC3 A;  4Y5I A;  4DAT A;  3RDH A;  5BTV A;  3T0L A;  1QJB A;  5D2D A;  4ZDR A;  5J31 A;  1A38 A;  3IQJ A;  1O9F A;  3M51 A;  3UAL A;  4ZQ0 A;  4DHM A;  3SP5 A; 
#chains in the Genus database with same CATH topology
 4DHS A;  1IB1 A;  5HF3 A;  3U9X A;  3P1O A;  3E6Y A;  1O9D A;  1I5P A;  5IQP A;  1S2X A;  3P1N A;  3AXY C;  2B05 A;  5D3F A;  3P1Q A;  4N7G A;  3MHR A;  1YWT A;  3P1S A;  4W8J A;  3UBW A;  1W99 A;  5LU2 A;  5BY9 A;  5LU1 A;  4GNT A;  4O46 A;  3LW1 A;  3P1P A;  1A4O A;  3SML A;  4IHL A;  5EWZ A;  3X0U A;  4DHQ A;  4N7Y A;  5LVZ A;  2C74 A;  4FJ3 A;  3SMK A;  4FL5 A;  3T0M A;  5LHO A;  4E2E A;  1QJA A;  2C63 A;  4DAU A;  1CIY A;  3EB7 A;  4DNK A;  4IEA A;  4ZQ0 A;  3SMM A;  3I4R A;  3UX0 A;  3M50 A;  3SPR A;  5F74 A;  2C1N A;  2C9K A;  4F7R A;  3ZHE B;  4BG6 A;  4ARY A;  1O9E A;  5LX2 A;  2O02 A;  1O9C A;  4QX0 A;  4HKC A;  2BQ0 A;  3SMN A;  3SMO A;  4DHO A;  4DHU A;  3IQV A;  4QX2 A;  4QLI A;  4Y32 A;  5D3E A;  4Y3B A;  4DHN A;  3CU8 A;  4FR3 A;  1A37 A;  2BR9 A;  4DHP A;  3NKX A;  5EXA A;  4D8M A;  3CQG A;  4DHR A;  3CQC A;  4DHT A;  1YZ5 A;  2C1J A;  3EFZ A;  1JI6 A;  4J6S A;  2C23 A;  4N84 A;  2BTP A;  2WH0 A;  2NPM A;  4QX1 A;  3O8I A;  2V7D A;  3IQU A;  2O98 A;  3UZD A;  3P1R A;  4DX0 A;  4JDD A;  4MOA A;  4WRQ A;  4JC3 A;  4Y5I A;  4DAT A;  3RDH A;  5BTV A;  4ARX A;  3T0L A;  4QX3 A;  1QJB A;  1DLC A;  5D2D A;  4ZDR A;  5J31 A;  1A38 A;  3IQJ A;  1O9F A;  3M51 A;  3UAL A;  1URJ A;  2O8P A;  4DHM A;  3SP5 A; 
#chains in the Genus database with same CATH homology
 4DHS A;  1IB1 A;  5HF3 A;  3U9X A;  3P1O A;  3E6Y A;  1O9D A;  5IQP A;  3P1N A;  3AXY C;  2B05 A;  5D3F A;  3P1Q A;  4N7G A;  3MHR A;  1YWT A;  3P1S A;  3UBW A;  5LU2 A;  5BY9 A;  5LU1 A;  4GNT A;  4O46 A;  3LW1 A;  3P1P A;  1A4O A;  3SML A;  4IHL A;  5EWZ A;  4DHQ A;  5LVZ A;  4N7Y A;  2C74 A;  4FJ3 A;  3SMK A;  4FL5 A;  3T0M A;  5LHO A;  4E2E A;  1QJA A;  2C63 A;  4DAU A;  4DNK A;  4IEA A;  3SMM A;  3UX0 A;  3M50 A;  3SPR A;  5F74 A;  2C1N A;  4F7R A;  4BG6 A;  1O9E A;  5LX2 A;  2O02 A;  1O9C A;  4HKC A;  2BQ0 A;  3SMN A;  3SMO A;  4DHO A;  4DHU A;  3IQV A;  4QLI A;  4Y32 A;  5D3E A;  4Y3B A;  4DHN A;  3CU8 A;  4FR3 A;  1A37 A;  2BR9 A;  4DHP A;  3NKX A;  5EXA A;  4DHR A;  4DHT A;  1YZ5 A;  2C1J A;  3EFZ A;  4J6S A;  2C23 A;  4N84 A;  2BTP A;  2WH0 A;  2NPM A;  3O8I A;  2O8P A;  2V7D A;  3IQU A;  2O98 A;  3UZD A;  3P1R A;  4DX0 A;  4JDD A;  4WRQ A;  4JC3 A;  4Y5I A;  4DAT A;  3RDH A;  5BTV A;  3T0L A;  1QJB A;  5D2D A;  4ZDR A;  5J31 A;  1A38 A;  3IQJ A;  1O9F A;  3M51 A;  3UAL A;  4ZQ0 A;  4DHM A;  3SP5 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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3LW1A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations