3M50 | Genus

Total Genus 100

Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	100
sequence length	232
structure length	218
Chain Sequence	EENVYMAKLAEQAERYEEMVEFMEKVSNSLEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEEHVNSIREYRSKIENELSKICDGILKLLDAKLIPSAASGDSKVFYLKMKGDYHRYLAEFKTGAERKEAAESTLTAYKAAQDIATTELAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFDEAIAELDYKDSTLIMQLLRDNLTLWTSD

Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

loadScript /static/js/j2s/core/package.js

loadScript /static/js/j2s/core/corejmol.z.js

loadScript /static/js/j2s/core/corescript.z.js

JSmol exec jmolApplet0 start applet null

Jmol JavaScript applet jmolApplet0__646179642207064__ initializing

Jmol getValue debug null

Jmol getValue logLevel null

Jmol getValue allowjavascript null

AppletRegistry.checkIn(jmolApplet0__646179642207064__)

vwrOptions:

{ "name":"jmolApplet0","applet":true,"documentBase":"https://genus.fuw.edu.pl/view/3M50/A/","platform":"J.awtjs2d.Platform","fullName":"jmolApplet0__646179642207064__","codePath":"https:/static/js/j2s/","display":"jmolApplet0_canvas2d","signedApplet":"true","appletReadyCallback":"Jmol._readyCallback","statusListener":"[J.appletjs.Jmol object]","syncId":"646179642207064","bgcolor":"white" }

setting document base to "https://genus.fuw.edu.pl/view/3M50/A/"

Jmol Version: 14.29.13 2018-04-17 17:17

java.vendor: Java2Script (HTML5)

java.version: 2018-01-28 23:38:52 (JSmol/j2s)

os.name: Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)

Access: ALL

memory: 0.0/0.0

processors available: 1

useCommandThread: false

appletId:jmolApplet0 (signed)

Jmol getValue emulate null

defaults = "Jmol"

Jmol getValue boxbgcolor null

Jmol getValue bgcolor white

backgroundColor = "white"

Jmol getValue ANIMFRAMECallback null

Jmol getValue APPLETREADYCallback Jmol._readyCallback

APPLETREADYCallback = "Jmol._readyCallback"

callback set for APPLETREADYCallback Jmol._readyCallback APPLETREADY

Jmol getValue ATOMMOVEDCallback null

Jmol getValue AUDIOCallback null

Jmol getValue CLICKCallback null

Jmol getValue DRAGDROPCallback null

Jmol getValue ECHOCallback null

Jmol getValue ERRORCallback null

Jmol getValue EVALCallback null

Jmol getValue HOVERCallback null

Jmol getValue IMAGECallback null

Jmol getValue LOADSTRUCTCallback null

Jmol getValue MEASURECallback null

Jmol getValue MESSAGECallback null

Jmol getValue MINIMIZATIONCallback null

Jmol getValue SERVICECallback null

Jmol getValue PICKCallback null

Jmol getValue RESIZECallback null

Jmol getValue SCRIPTCallback null

Jmol getValue SYNCCallback null

Jmol getValue STRUCTUREMODIFIEDCallback null

Jmol getValue doTranslate null

language=en_US

Jmol getValue popupMenu null

Jmol getValue script null

Jmol getValue loadInline null

Jmol getValue load null

Jmol applet jmolApplet0__646179642207064__ ready

script 1 started

platformSpeed = 8

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Identification and structure of small-molecule stabilizers of 14-3-3 protein-protein interactions pubmed doi rcsb
molecule keywords	14-3-3-like protein C
molecule tags	Protein binding
source organism	Nicotiana tabacum
total genus	100
structure length	218
sequence length	232
ec nomenclature
pdb deposition date	2010-03-12

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00244	14-3-3	14-3-3 protein

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.190.20	Mainly Alpha	Up-down Bundle	Delta-Endotoxin; domain 1	14-3-3 domain	3m50A00

3EFZA 3O8IA 3P1SA 4DNKA 1A37A 3U9XA 3E6YA 3NKXA 4N7YA 4DHSA 3UBWA 3SMLA 4WRQA 4DHTA 3M50A 4FR3A 4HKCA 5LHOA 4N7GA 3P1PA 2BQ0A 3CU8A 4DX0A 4DHMA 2B05A 5F74A 4FL5A 4DHUA 4E2EA 5EXAA 4Y3BA 3MHRA 4DATA 4DAUA 4FJ3A 1YWTA 4IHLA 4F7RA 2C23A 4DHQA 1O9DA 2BR9A 2NPMA 5LVZA 3SMKA 5J31A 1O9EA 2O02A 4JC3A 4J6SA 2BTPA 2WH0A 4DHPA 3P1RA 2C74A 3SP5A 5D3FA 3UZDA 1A38A 4JDDA 4N84A 4GNTA 5BY9A 2C63A 5LU1A 3AXYC 4DHRA 4Y5IA 2C1JA 5D2DA 4DHOA 1QJBA 3IQVA 5LX2A 3IQJA 3SMNA 3T0LA 4O46A 5EWZA 4QLIA 2C1NA 3IQUA 3SMMA 1O9FA 4Y32A 5IQPA 5LU2A 3LW1A 3P1OA 1O9CA 4ZDRA 3UALA 2V7DA 3RDHA 1A4OA 3P1NA 3M51A 4DHNA 1IB1A 1YZ5A 1QJAA 5HF3A 3P1QA 2O8PA 5D3EA 3SPRA 3SMOA 4IEAA 3UX0A 4BG6A 3T0MA 2O98A 5BTVA 4ZQ0A
chains in the Genus database with same CATH superfamily

3EFZA 3O8IA 3P1SA 4DNKA 1A37A 3U9XA 3E6YA 3NKXA 4N7YA 4MOAA 4DHSA 3UBWA 3SMLA 4WRQA 4DHTA 3M50A 4FR3A 4HKCA 4D8MA 5LHOA 4N7GA 3P1PA 2BQ0A 3CU8A 4DX0A 4DHMA 2B05A 5F74A 4FL5A 1DLCA 4DHUA 4E2EA 5EXAA 4Y3BA 4QX0A 3MHRA 4DATA 4DAUA 3I4RA 4FJ3A 1YWTA 4IHLA 4F7RA 2C23A 4DHQA 1O9DA 1URJA 2BR9A 2NPMA 5LVZA 3SMKA 5J31A 1O9EA 2O02A 1S2XA 4ARXA 4JC3A 4J6SA 2BTPA 2WH0A 4DHPA 3P1RA 2C74A 3SP5A 5D3FA 3UZDA 1I5PA 3X0UA 1A38A 1CIYA 4JDDA 4N84A 4GNTA 5BY9A 4ARYA 2C63A 5LU1A 3AXYC 4DHRA 4QX2A 2C1JA 4Y5IA 5D2DA 4DHOA 1QJBA 3IQVA 1W99A 5LX2A 3IQJA 3SMNA 3T0LA 4O46A 5EWZA 4QLIA 2C1NA 3IQUA 3SMMA 3ZHEB 1O9FA 4Y32A 5IQPA 5LU2A 3LW1A 3P1OA 1O9CA 1JI6A 4ZDRA 3UALA 2V7DA 3RDHA 1A4OA 4W8JA 3P1NA 3M51A 2C9KA 4DHNA 1IB1A 1YZ5A 3CQGA 1QJAA 5HF3A 3P1QA 2O8PA 5D3EA 3EB7A 3SPRA 3CQCA 4IEAA 3SMOA 3UX0A 4QX1A 4BG6A 3T0MA 2O98A 5BTVA 4ZQ0A 4QX3A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3EFZ A;  3O8I A;  3P1S A;  4DNK A;  1A37 A;  3U9X A;  3E6Y A;  3NKX A;  4N7Y A;  4DHS A;  3UBW A;  3SML A;  4WRQ A;  4DHT A;  3M50 A;  4FR3 A;  4HKC A;  5LHO A;  4N7G A;  3P1P A;  2BQ0 A;  3CU8 A;  4DX0 A;  4DHM A;  2B05 A;  5F74 A;  4FL5 A;  4DHU A;  4E2E A;  5EXA A;  4Y3B A;  3MHR A;  4DAT A;  4DAU A;  4FJ3 A;  1YWT A;  4IHL A;  4F7R A;  2C23 A;  4DHQ A;  1O9D A;  2BR9 A;  2NPM A;  5LVZ A;  3SMK A;  5J31 A;  1O9E A;  2O02 A;  4JC3 A;  4J6S A;  2BTP A;  2WH0 A;  4DHP A;  3P1R A;  2C74 A;  3SP5 A;  5D3F A;  3UZD A;  1A38 A;  4JDD A;  4N84 A;  4GNT A;  5BY9 A;  2C63 A;  5LU1 A;  3AXY C;  4DHR A;  4Y5I A;  2C1J A;  5D2D A;  4DHO A;  1QJB A;  3IQV A;  5LX2 A;  3IQJ A;  3SMN A;  3T0L A;  4O46 A;  5EWZ A;  4QLI A;  2C1N A;  3IQU A;  3SMM A;  1O9F A;  4Y32 A;  5IQP A;  5LU2 A;  3LW1 A;  3P1O A;  1O9C A;  4ZDR A;  3UAL A;  2V7D A;  3RDH A;  1A4O A;  3P1N A;  3M51 A;  4DHN A;  1IB1 A;  1YZ5 A;  1QJA A;  5HF3 A;  3P1Q A;  2O8P A;  5D3E A;  3SPR A;  3SMO A;  4IEA A;  3UX0 A;  4BG6 A;  3T0M A;  2O98 A;  5BTV A;  4ZQ0 A; 
#chains in the Genus database with same CATH topology
 3EFZ A;  3O8I A;  3P1S A;  4DNK A;  1A37 A;  3U9X A;  3E6Y A;  3NKX A;  4N7Y A;  4MOA A;  4DHS A;  3UBW A;  3SML A;  4WRQ A;  4DHT A;  3M50 A;  4FR3 A;  4HKC A;  4D8M A;  5LHO A;  4N7G A;  3P1P A;  2BQ0 A;  3CU8 A;  4DX0 A;  4DHM A;  2B05 A;  5F74 A;  4FL5 A;  1DLC A;  4DHU A;  4E2E A;  5EXA A;  4Y3B A;  4QX0 A;  3MHR A;  4DAT A;  4DAU A;  3I4R A;  4FJ3 A;  1YWT A;  4IHL A;  4F7R A;  2C23 A;  4DHQ A;  1O9D A;  1URJ A;  2BR9 A;  2NPM A;  5LVZ A;  3SMK A;  5J31 A;  1O9E A;  2O02 A;  1S2X A;  4ARX A;  4JC3 A;  4J6S A;  2BTP A;  2WH0 A;  4DHP A;  3P1R A;  2C74 A;  3SP5 A;  5D3F A;  3UZD A;  1I5P A;  3X0U A;  1A38 A;  1CIY A;  4JDD A;  4N84 A;  4GNT A;  5BY9 A;  4ARY A;  2C63 A;  5LU1 A;  3AXY C;  4DHR A;  4QX2 A;  2C1J A;  4Y5I A;  5D2D A;  4DHO A;  1QJB A;  3IQV A;  1W99 A;  5LX2 A;  3IQJ A;  3SMN A;  3T0L A;  4O46 A;  5EWZ A;  4QLI A;  2C1N A;  3IQU A;  3SMM A;  3ZHE B;  1O9F A;  4Y32 A;  5IQP A;  5LU2 A;  3LW1 A;  3P1O A;  1O9C A;  1JI6 A;  4ZDR A;  3UAL A;  2V7D A;  3RDH A;  1A4O A;  4W8J A;  3P1N A;  3M51 A;  2C9K A;  4DHN A;  1IB1 A;  1YZ5 A;  3CQG A;  1QJA A;  5HF3 A;  3P1Q A;  2O8P A;  5D3E A;  3EB7 A;  3SPR A;  3CQC A;  4IEA A;  3SMO A;  3UX0 A;  4QX1 A;  4BG6 A;  3T0M A;  2O98 A;  5BTV A;  4ZQ0 A;  4QX3 A; 
#chains in the Genus database with same CATH homology
 3EFZ A;  3O8I A;  3P1S A;  4DNK A;  1A37 A;  3U9X A;  3E6Y A;  3NKX A;  4N7Y A;  4DHS A;  3UBW A;  3SML A;  4WRQ A;  4DHT A;  3M50 A;  4FR3 A;  4HKC A;  5LHO A;  4N7G A;  3P1P A;  2BQ0 A;  3CU8 A;  4DX0 A;  4DHM A;  2B05 A;  5F74 A;  4FL5 A;  4DHU A;  4E2E A;  5EXA A;  4Y3B A;  3MHR A;  4DAT A;  4DAU A;  4FJ3 A;  1YWT A;  4IHL A;  4F7R A;  2C23 A;  4DHQ A;  1O9D A;  2BR9 A;  2NPM A;  5LVZ A;  3SMK A;  5J31 A;  1O9E A;  2O02 A;  4JC3 A;  4J6S A;  2BTP A;  2WH0 A;  4DHP A;  3P1R A;  2C74 A;  3SP5 A;  5D3F A;  3UZD A;  1A38 A;  4JDD A;  4N84 A;  4GNT A;  5BY9 A;  2C63 A;  5LU1 A;  3AXY C;  4DHR A;  4Y5I A;  2C1J A;  5D2D A;  4DHO A;  1QJB A;  3IQV A;  5LX2 A;  3IQJ A;  3SMN A;  3T0L A;  4O46 A;  5EWZ A;  4QLI A;  2C1N A;  3IQU A;  3SMM A;  1O9F A;  4Y32 A;  5IQP A;  5LU2 A;  3LW1 A;  3P1O A;  1O9C A;  4ZDR A;  3UAL A;  2V7D A;  3RDH A;  1A4O A;  3P1N A;  3M51 A;  4DHN A;  1IB1 A;  1YZ5 A;  1QJA A;  5HF3 A;  3P1Q A;  2O8P A;  5D3E A;  3SPR A;  3SMO A;  4IEA A;  3UX0 A;  4BG6 A;  3T0M A;  2O98 A;  5BTV A;  4ZQ0 A;

...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)

...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

3M50A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations