3P1O | Genus

Total Genus 98

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	98
sequence length	235
structure length	233
Chain Sequence	AMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVREYREVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Peptide binding protein
source organism	Homo sapiens
publication title	A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface pubmed doi rcsb
molecule keywords	14-3-3 protein sigma
total genus	98
structure length	233
sequence length	235
ec nomenclature
pdb deposition date	2010-09-30

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00244	14-3-3	14-3-3 protein

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.190.20	Mainly Alpha	Up-down Bundle	Delta-Endotoxin; domain 1	14-3-3 domain	3p1oA00

3CU8A 2BQ0A 2BTPA 4DX0A 4ZDRA 4DHPA 1YZ5A 4E2EA 5D3FA 4DHNA 5BY9A 3RDHA 4DATA 4DHRA 2O98A 2V7DA 3E6YA 3UALA 3LW1A 5HF3A 5LVZA 4BG6A 4HKCA 4N7GA 1YWTA 3AXYC 3UZDA 2O8PA 1O9DA 5LX2A 4DNKA 4DAUA 4DHMA 4F7RA 4J6SA 4DHUA 3SMNA 1A38A 5EWZA 3UBWA 3T0MA 4FR3A 2C23A 2B05A 3SPRA 4Y32A 2C74A 1O9EA 1QJAA 3P1QA 3P1OA 3SMLA 3M51A 3T0LA 4DHOA 4DHTA 4IEAA 2C63A 3NKXA 4ZQ0A 1A4OA 3IQJA 3SP5A 3IQUA 4QLIA 3SMOA 5D2DA 4WRQA 4Y3BA 4N7YA 3U9XA 1O9FA 2O02A 3P1RA 3IQVA 5IQPA 3O8IA 1QJBA 3MHRA 4DHSA 4JC3A 5LU2A 3SMMA 4DHQA 5F74A 3P1NA 4JDDA 3SMKA 4O46A 2C1JA 4IHLA 5BTVA 4N84A 2WH0A 4GNTA 5D3EA 4FL5A 4FJ3A 2BR9A 5EXAA 4Y5IA 3P1PA 1IB1A 3UX0A 2NPMA 2C1NA 3M50A 1A37A 3EFZA 5LHOA 5LU1A 3P1SA 5J31A 1O9CA
chains in the Genus database with same CATH superfamily

3CU8A 2BQ0A 2BTPA 4DX0A 1DLCA 4ZDRA 4DHPA 1YZ5A 4E2EA 5D3FA 4DHNA 1I5PA 5BY9A 3ZHEB 3RDHA 4DATA 4DHRA 2O98A 2V7DA 3E6YA 1URJA 3UALA 3LW1A 5HF3A 3CQGA 5LVZA 1S2XA 4BG6A 4HKCA 4N7GA 1YWTA 3AXYC 3UZDA 2O8PA 1O9DA 5LX2A 4DNKA 4DAUA 4DHMA 4F7RA 1JI6A 4J6SA 4DHUA 3SMNA 1A38A 5EWZA 3UBWA 3T0MA 4W8JA 4FR3A 2C23A 2B05A 3SPRA 4Y32A 3I4RA 2C74A 1O9EA 1QJAA 3P1QA 3P1OA 3SMLA 3M51A 3T0LA 4DHOA 4DHTA 4IEAA 2C9KA 2C63A 3NKXA 4ZQ0A 1A4OA 3IQJA 3SP5A 3IQUA 4QLIA 3SMOA 5D2DA 4WRQA 4ARYA 4Y3BA 4QX3A 3X0UA 4N7YA 3U9XA 1O9FA 2O02A 3P1RA 3IQVA 5IQPA 3O8IA 1QJBA 3MHRA 3EB7A 4DHSA 4JC3A 5LU2A 3SMMA 4DHQA 3P1NA 5F74A 4JDDA 3SMKA 4O46A 2C1JA 3CQCA 4IHLA 5BTVA 4N84A 2WH0A 1CIYA 4GNTA 5D3EA 4FL5A 4QX1A 4FJ3A 4QX2A 4ARXA 2BR9A 5EXAA 4Y5IA 3P1PA 1IB1A 3UX0A 4D8MA 2NPMA 2C1NA 3M50A 1A37A 3EFZA 5LHOA 5LU1A 4MOAA 4QX0A 3P1SA 1W99A 5J31A 1O9CA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3CU8 A;  2BQ0 A;  2BTP A;  4DX0 A;  4ZDR A;  4DHP A;  1YZ5 A;  4E2E A;  5D3F A;  4DHN A;  5BY9 A;  3RDH A;  4DAT A;  4DHR A;  2O98 A;  2V7D A;  3E6Y A;  3UAL A;  3LW1 A;  5HF3 A;  5LVZ A;  4BG6 A;  4HKC A;  4N7G A;  1YWT A;  3AXY C;  3UZD A;  2O8P A;  1O9D A;  5LX2 A;  4DNK A;  4DAU A;  4DHM A;  4F7R A;  4J6S A;  4DHU A;  3SMN A;  1A38 A;  5EWZ A;  3UBW A;  3T0M A;  4FR3 A;  2C23 A;  2B05 A;  3SPR A;  4Y32 A;  2C74 A;  1O9E A;  1QJA A;  3P1Q A;  3P1O A;  3SML A;  3M51 A;  3T0L A;  4DHO A;  4DHT A;  4IEA A;  2C63 A;  3NKX A;  4ZQ0 A;  1A4O A;  3IQJ A;  3SP5 A;  3IQU A;  4QLI A;  3SMO A;  5D2D A;  4WRQ A;  4Y3B A;  4N7Y A;  3U9X A;  1O9F A;  2O02 A;  3P1R A;  3IQV A;  5IQP A;  3O8I A;  1QJB A;  3MHR A;  4DHS A;  4JC3 A;  5LU2 A;  3SMM A;  4DHQ A;  5F74 A;  3P1N A;  4JDD A;  3SMK A;  4O46 A;  2C1J A;  4IHL A;  5BTV A;  4N84 A;  2WH0 A;  4GNT A;  5D3E A;  4FL5 A;  4FJ3 A;  2BR9 A;  5EXA A;  4Y5I A;  3P1P A;  1IB1 A;  3UX0 A;  2NPM A;  2C1N A;  3M50 A;  1A37 A;  3EFZ A;  5LHO A;  5LU1 A;  3P1S A;  5J31 A;  1O9C A; 
#chains in the Genus database with same CATH topology
 3CU8 A;  2BQ0 A;  2BTP A;  4DX0 A;  1DLC A;  4ZDR A;  4DHP A;  1YZ5 A;  4E2E A;  5D3F A;  4DHN A;  1I5P A;  5BY9 A;  3ZHE B;  3RDH A;  4DAT A;  4DHR A;  2O98 A;  2V7D A;  3E6Y A;  1URJ A;  3UAL A;  3LW1 A;  5HF3 A;  3CQG A;  5LVZ A;  1S2X A;  4BG6 A;  4HKC A;  4N7G A;  1YWT A;  3AXY C;  3UZD A;  2O8P A;  1O9D A;  5LX2 A;  4DNK A;  4DAU A;  4DHM A;  4F7R A;  1JI6 A;  4J6S A;  4DHU A;  3SMN A;  1A38 A;  5EWZ A;  3UBW A;  3T0M A;  4W8J A;  4FR3 A;  2C23 A;  2B05 A;  3SPR A;  4Y32 A;  3I4R A;  2C74 A;  1O9E A;  1QJA A;  3P1Q A;  3P1O A;  3SML A;  3M51 A;  3T0L A;  4DHO A;  4DHT A;  4IEA A;  2C9K A;  2C63 A;  3NKX A;  4ZQ0 A;  1A4O A;  3IQJ A;  3SP5 A;  3IQU A;  4QLI A;  3SMO A;  5D2D A;  4WRQ A;  4ARY A;  4Y3B A;  4QX3 A;  3X0U A;  4N7Y A;  3U9X A;  1O9F A;  2O02 A;  3P1R A;  3IQV A;  5IQP A;  3O8I A;  1QJB A;  3MHR A;  3EB7 A;  4DHS A;  4JC3 A;  5LU2 A;  3SMM A;  4DHQ A;  3P1N A;  5F74 A;  4JDD A;  3SMK A;  4O46 A;  2C1J A;  3CQC A;  4IHL A;  5BTV A;  4N84 A;  2WH0 A;  1CIY A;  4GNT A;  5D3E A;  4FL5 A;  4QX1 A;  4FJ3 A;  4QX2 A;  4ARX A;  2BR9 A;  5EXA A;  4Y5I A;  3P1P A;  1IB1 A;  3UX0 A;  4D8M A;  2NPM A;  2C1N A;  3M50 A;  1A37 A;  3EFZ A;  5LHO A;  5LU1 A;  4MOA A;  4QX0 A;  3P1S A;  1W99 A;  5J31 A;  1O9C A; 
#chains in the Genus database with same CATH homology
 3CU8 A;  2BQ0 A;  2BTP A;  4DX0 A;  4ZDR A;  4DHP A;  1YZ5 A;  4E2E A;  5D3F A;  4DHN A;  5BY9 A;  3RDH A;  4DAT A;  4DHR A;  2O98 A;  2V7D A;  3E6Y A;  3UAL A;  3LW1 A;  5HF3 A;  5LVZ A;  4BG6 A;  4HKC A;  4N7G A;  1YWT A;  3AXY C;  3UZD A;  2O8P A;  1O9D A;  5LX2 A;  4DNK A;  4DAU A;  4DHM A;  4F7R A;  4J6S A;  4DHU A;  3SMN A;  1A38 A;  5EWZ A;  3UBW A;  3T0M A;  4FR3 A;  2C23 A;  2B05 A;  3SPR A;  4Y32 A;  2C74 A;  1O9E A;  1QJA A;  3P1Q A;  3P1O A;  3SML A;  3M51 A;  3T0L A;  4DHO A;  4DHT A;  4IEA A;  2C63 A;  3NKX A;  4ZQ0 A;  1A4O A;  3IQJ A;  3SP5 A;  3IQU A;  4QLI A;  3SMO A;  5D2D A;  4WRQ A;  4Y3B A;  4N7Y A;  3U9X A;  1O9F A;  2O02 A;  3P1R A;  3IQV A;  5IQP A;  3O8I A;  1QJB A;  3MHR A;  4DHS A;  4JC3 A;  5LU2 A;  3SMM A;  4DHQ A;  5F74 A;  3P1N A;  4JDD A;  3SMK A;  4O46 A;  2C1J A;  4IHL A;  5BTV A;  4N84 A;  2WH0 A;  4GNT A;  5D3E A;  4FL5 A;  4FJ3 A;  2BR9 A;  5EXA A;  4Y5I A;  3P1P A;  1IB1 A;  3UX0 A;  2NPM A;  2C1N A;  3M50 A;  1A37 A;  3EFZ A;  5LHO A;  5LU1 A;  3P1S A;  5J31 A;  1O9C A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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3P1OA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations