3P1SA

Crystal structure of human 14-3-3 sigma c38n/n166h in complex with task-3 peptide and stabilizer fusicoccin a
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
236
structure length
236
Chain Sequence
GAMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSVEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTHPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface
pubmed doi rcsb
molecule tags Peptide binding protein
source organism Homo sapiens
molecule keywords 14-3-3 protein sigma
total genus 101
structure length 236
sequence length 236
ec nomenclature
pdb deposition date 2010-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 3p1sA00
5J31A 2C1NA 1A4OA 2B05A 3P1OA 3P1PA 4DHRA 3SMOA 4DHTA 3IQJA 5BY9A 4DHNA 5EWZA 5D3EA 4F7RA 4FL5A 4J6SA 3CU8A 2O8PA 1IB1A 5EXAA 3O8IA 3P1NA 4DAUA 5LU1A 3P1SA 3M50A 3UX0A 4FJ3A 5LX2A 3SMLA 4IHLA 3U9XA 5BTVA 4N84A 2BTPA 4DNKA 3SMMA 5HF3A 4DHPA 3P1QA 3AXYC 4DATA 1YWTA 1A37A 4DHSA 3T0LA 3SMKA 5LHOA 3SMNA 3SPRA 3LW1A 4BG6A 4N7GA 3UBWA 3IQVA 4O46A 2V7DA 2BQ0A 3UZDA 4ZQ0A 2WH0A 5LU2A 2C63A 1O9EA 5LVZA 4DHUA 4DHOA 4E2EA 4JDDA 3MHRA 3EFZA 5IQPA 1A38A 2C74A 3IQUA 3T0MA 4DHMA 4WRQA 2BR9A 2C23A 4N7YA 4DHQA 2NPMA 4Y5IA 4Y3BA 1QJBA 3SP5A 4QLIA 3M51A 3E6YA 3NKXA 3UALA 5D2DA 2C1JA 4IEAA 4FR3A 1YZ5A 4JC3A 4ZDRA 3P1RA 1O9DA 4Y32A 1QJAA 4GNTA 5D3FA 2O98A 4DX0A 3RDHA 1O9CA 2O02A 1O9FA 5F74A 4HKCA
chains in the Genus database with same CATH superfamily
5J31A 2C1NA 1A4OA 2B05A 3P1OA 3P1PA 4DHRA 3SMOA 3CQGA 4DHTA 3IQJA 5BY9A 4DHNA 5EWZA 1S2XA 5D3EA 4F7RA 4FL5A 4J6SA 3CU8A 2O8PA 1IB1A 5EXAA 3O8IA 3P1NA 4DAUA 5LU1A 3P1SA 3M50A 3UX0A 4FJ3A 5LX2A 4QX1A 3SMLA 4IHLA 3U9XA 5BTVA 4ARYA 4N84A 2BTPA 4DNKA 3SMMA 4QX2A 1W99A 3X0UA 5HF3A 4DHPA 3P1QA 3AXYC 4DATA 1YWTA 1DLCA 1JI6A 1A37A 4DHSA 3T0LA 3SMKA 5LHOA 3SMNA 3SPRA 3LW1A 4BG6A 4N7GA 3UBWA 3IQVA 4O46A 1I5PA 2V7DA 3ZHEB 4ARXA 2C9KA 2BQ0A 3UZDA 4ZQ0A 1CIYA 2WH0A 3I4RA 5LU2A 2C63A 1O9EA 4MOAA 5LVZA 4DHUA 4DHOA 4E2EA 4JDDA 3MHRA 3EFZA 4QX0A 5IQPA 1A38A 2C74A 3IQUA 3T0MA 4DHMA 4WRQA 2BR9A 2C23A 4N7YA 4DHQA 2NPMA 4Y5IA 4D8MA 3EB7A 4Y3BA 1QJBA 3SP5A 4QLIA 3M51A 3E6YA 3NKXA 4W8JA 3UALA 5D2DA 2C1JA 4IEAA 4FR3A 1YZ5A 4JC3A 4ZDRA 3P1RA 1O9DA 4Y32A 1QJAA 1URJA 4GNTA 5D3FA 2O98A 3CQCA 4QX3A 3RDHA 4DX0A 1O9CA 2O02A 1O9FA 5F74A 4HKCA
chains in the Genus database with same CATH topology
5J31A 2C1NA 1A4OA 2B05A 3P1OA 3P1PA 4DHRA 3SMOA 4DHTA 3IQJA 5BY9A 4DHNA 5EWZA 5D3EA 4F7RA 4FL5A 4J6SA 3CU8A 2O8PA 1IB1A 5EXAA 3O8IA 3P1NA 4DAUA 5LU1A 3P1SA 3M50A 3UX0A 4FJ3A 5LX2A 3SMLA 4IHLA 3U9XA 5BTVA 4N84A 2BTPA 4DNKA 3SMMA 5HF3A 4DHPA 3P1QA 3AXYC 4DATA 1YWTA 1A37A 4DHSA 3T0LA 3SMKA 5LHOA 3SMNA 3SPRA 3LW1A 4BG6A 4N7GA 3UBWA 3IQVA 4O46A 2V7DA 2BQ0A 3UZDA 4ZQ0A 2WH0A 5LU2A 2C63A 1O9EA 5LVZA 4DHUA 4DHOA 4E2EA 4JDDA 3MHRA 3EFZA 5IQPA 1A38A 2C74A 3IQUA 3T0MA 4DHMA 4WRQA 2BR9A 2C23A 4N7YA 4DHQA 2NPMA 4Y5IA 4Y3BA 1QJBA 3SP5A 4QLIA 3M51A 3E6YA 3NKXA 3UALA 5D2DA 2C1JA 4IEAA 4FR3A 1YZ5A 4JC3A 4ZDRA 3P1RA 1O9DA 4Y32A 1QJAA 4GNTA 5D3FA 2O98A 4DX0A 3RDHA 1O9CA 2O02A 1O9FA 5F74A 4HKCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5J31 A;  2C1N A;  1A4O A;  2B05 A;  3P1O A;  3P1P A;  4DHR A;  3SMO A;  4DHT A;  3IQJ A;  5BY9 A;  4DHN A;  5EWZ A;  5D3E A;  4F7R A;  4FL5 A;  4J6S A;  3CU8 A;  2O8P A;  1IB1 A;  5EXA A;  3O8I A;  3P1N A;  4DAU A;  5LU1 A;  3P1S A;  3M50 A;  3UX0 A;  4FJ3 A;  5LX2 A;  3SML A;  4IHL A;  3U9X A;  5BTV A;  4N84 A;  2BTP A;  4DNK A;  3SMM A;  5HF3 A;  4DHP A;  3P1Q A;  3AXY C;  4DAT A;  1YWT A;  1A37 A;  4DHS A;  3T0L A;  3SMK A;  5LHO A;  3SMN A;  3SPR A;  3LW1 A;  4BG6 A;  4N7G A;  3UBW A;  3IQV A;  4O46 A;  2V7D A;  2BQ0 A;  3UZD A;  4ZQ0 A;  2WH0 A;  5LU2 A;  2C63 A;  1O9E A;  5LVZ A;  4DHU A;  4DHO A;  4E2E A;  4JDD A;  3MHR A;  3EFZ A;  5IQP A;  1A38 A;  2C74 A;  3IQU A;  3T0M A;  4DHM A;  4WRQ A;  2BR9 A;  2C23 A;  4N7Y A;  4DHQ A;  2NPM A;  4Y5I A;  4Y3B A;  1QJB A;  3SP5 A;  4QLI A;  3M51 A;  3E6Y A;  3NKX A;  3UAL A;  5D2D A;  2C1J A;  4IEA A;  4FR3 A;  1YZ5 A;  4JC3 A;  4ZDR A;  3P1R A;  1O9D A;  4Y32 A;  1QJA A;  4GNT A;  5D3F A;  2O98 A;  4DX0 A;  3RDH A;  1O9C A;  2O02 A;  1O9F A;  5F74 A;  4HKC A; 
#chains in the Genus database with same CATH topology
 5J31 A;  2C1N A;  1A4O A;  2B05 A;  3P1O A;  3P1P A;  4DHR A;  3SMO A;  3CQG A;  4DHT A;  3IQJ A;  5BY9 A;  4DHN A;  5EWZ A;  1S2X A;  5D3E A;  4F7R A;  4FL5 A;  4J6S A;  3CU8 A;  2O8P A;  1IB1 A;  5EXA A;  3O8I A;  3P1N A;  4DAU A;  5LU1 A;  3P1S A;  3M50 A;  3UX0 A;  4FJ3 A;  5LX2 A;  4QX1 A;  3SML A;  4IHL A;  3U9X A;  5BTV A;  4ARY A;  4N84 A;  2BTP A;  4DNK A;  3SMM A;  4QX2 A;  1W99 A;  3X0U A;  5HF3 A;  4DHP A;  3P1Q A;  3AXY C;  4DAT A;  1YWT A;  1DLC A;  1JI6 A;  1A37 A;  4DHS A;  3T0L A;  3SMK A;  5LHO A;  3SMN A;  3SPR A;  3LW1 A;  4BG6 A;  4N7G A;  3UBW A;  3IQV A;  4O46 A;  1I5P A;  2V7D A;  3ZHE B;  4ARX A;  2C9K A;  2BQ0 A;  3UZD A;  4ZQ0 A;  1CIY A;  2WH0 A;  3I4R A;  5LU2 A;  2C63 A;  1O9E A;  4MOA A;  5LVZ A;  4DHU A;  4DHO A;  4E2E A;  4JDD A;  3MHR A;  3EFZ A;  4QX0 A;  5IQP A;  1A38 A;  2C74 A;  3IQU A;  3T0M A;  4DHM A;  4WRQ A;  2BR9 A;  2C23 A;  4N7Y A;  4DHQ A;  2NPM A;  4Y5I A;  4D8M A;  3EB7 A;  4Y3B A;  1QJB A;  3SP5 A;  4QLI A;  3M51 A;  3E6Y A;  3NKX A;  4W8J A;  3UAL A;  5D2D A;  2C1J A;  4IEA A;  4FR3 A;  1YZ5 A;  4JC3 A;  4ZDR A;  3P1R A;  1O9D A;  4Y32 A;  1QJA A;  1URJ A;  4GNT A;  5D3F A;  2O98 A;  3CQC A;  4QX3 A;  3RDH A;  4DX0 A;  1O9C A;  2O02 A;  1O9F A;  5F74 A;  4HKC A; 
#chains in the Genus database with same CATH homology
 5J31 A;  2C1N A;  1A4O A;  2B05 A;  3P1O A;  3P1P A;  4DHR A;  3SMO A;  4DHT A;  3IQJ A;  5BY9 A;  4DHN A;  5EWZ A;  5D3E A;  4F7R A;  4FL5 A;  4J6S A;  3CU8 A;  2O8P A;  1IB1 A;  5EXA A;  3O8I A;  3P1N A;  4DAU A;  5LU1 A;  3P1S A;  3M50 A;  3UX0 A;  4FJ3 A;  5LX2 A;  3SML A;  4IHL A;  3U9X A;  5BTV A;  4N84 A;  2BTP A;  4DNK A;  3SMM A;  5HF3 A;  4DHP A;  3P1Q A;  3AXY C;  4DAT A;  1YWT A;  1A37 A;  4DHS A;  3T0L A;  3SMK A;  5LHO A;  3SMN A;  3SPR A;  3LW1 A;  4BG6 A;  4N7G A;  3UBW A;  3IQV A;  4O46 A;  2V7D A;  2BQ0 A;  3UZD A;  4ZQ0 A;  2WH0 A;  5LU2 A;  2C63 A;  1O9E A;  5LVZ A;  4DHU A;  4DHO A;  4E2E A;  4JDD A;  3MHR A;  3EFZ A;  5IQP A;  1A38 A;  2C74 A;  3IQU A;  3T0M A;  4DHM A;  4WRQ A;  2BR9 A;  2C23 A;  4N7Y A;  4DHQ A;  2NPM A;  4Y5I A;  4Y3B A;  1QJB A;  3SP5 A;  4QLI A;  3M51 A;  3E6Y A;  3NKX A;  3UAL A;  5D2D A;  2C1J A;  4IEA A;  4FR3 A;  1YZ5 A;  4JC3 A;  4ZDR A;  3P1R A;  1O9D A;  4Y32 A;  1QJA A;  4GNT A;  5D3F A;  2O98 A;  4DX0 A;  3RDH A;  1O9C A;  2O02 A;  1O9F A;  5F74 A;  4HKC A; 
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