3SML | Genus

Total Genus 98

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	98
sequence length	236
structure length	236
Chain Sequence	GAMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSNEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTHPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Peptide binding protein
source organism	Homo sapiens
publication title	A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface. pubmed doi rcsb
molecule keywords	14-3-3 protein sigma
total genus	98
structure length	236
sequence length	236
ec nomenclature
pdb deposition date	2011-06-28

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00244	14-3-3	14-3-3 protein

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.190.20	Mainly Alpha	Up-down Bundle	Delta-Endotoxin; domain 1	14-3-3 domain	3smlA00

4WRQA 3SMNA 4DHSA 3P1NA 4N7YA 4DHQA 2BR9A 3LW1A 4JC3A 3SPRA 1O9EA 1O9DA 5EXAA 3O8IA 4DATA 2C23A 5LU1A 5IQPA 4DHMA 4IHLA 2O98A 4GNTA 4DHNA 2O02A 4DHOA 4DHPA 4ZQ0A 3IQUA 1IB1A 2C74A 1A37A 3IQVA 3CU8A 4DAUA 3T0MA 4J6SA 5BY9A 4FR3A 2WH0A 2C63A 3E6YA 4O46A 4DHTA 2B05A 3P1OA 5EWZA 3SMMA 5HF3A 5F74A 3RDHA 3P1PA 4FJ3A 1A38A 3AXYC 3NKXA 5LU2A 2BQ0A 3UZDA 4BG6A 1YWTA 2NPMA 3T0LA 5D3EA 3P1RA 4N84A 3UX0A 3U9XA 4QLIA 2V7DA 3P1SA 3SMLA 2BTPA 2C1JA 4Y32A 1QJAA 4JDDA 5LVZA 3SMKA 4Y3BA 1O9CA 3MHRA 5D3FA 3UALA 2O8PA 4FL5A 5D2DA 5LHOA 1QJBA 4DHUA 5LX2A 4ZDRA 3P1QA 3UBWA 4DX0A 3EFZA 3M50A 4N7GA 1O9FA 2C1NA 1YZ5A 3M51A 5J31A 4IEAA 4HKCA 4DHRA 4Y5IA 4F7RA 1A4OA 4DNKA 5BTVA 3SMOA 3IQJA 3SP5A 4E2EA
chains in the Genus database with same CATH superfamily

2C9KA 4WRQA 3SMNA 4DHSA 4MOAA 3P1NA 4ARYA 4N7YA 4DHQA 2BR9A 3LW1A 4JC3A 3SPRA 1O9EA 1O9DA 5EXAA 3O8IA 4DATA 2C23A 5LU1A 5IQPA 4DHMA 1CIYA 4IHLA 2O98A 4QX0A 4GNTA 4DHNA 2O02A 4DHOA 1S2XA 4QX3A 4DHPA 4ZQ0A 3IQUA 1IB1A 2C74A 1A37A 3IQVA 3CU8A 4DAUA 3T0MA 4J6SA 1DLCA 4QX2A 5BY9A 4FR3A 2WH0A 2C63A 3E6YA 4O46A 4DHTA 2B05A 3P1OA 5EWZA 3SMMA 5HF3A 5F74A 3RDHA 3P1PA 4FJ3A 1A38A 3AXYC 3NKXA 5LU2A 2BQ0A 3UZDA 4BG6A 4D8MA 1YWTA 1I5PA 2NPMA 3T0LA 5D3EA 3P1RA 4N84A 3UX0A 4QX1A 3U9XA 4QLIA 2V7DA 3ZHEB 3P1SA 3SMLA 2BTPA 2C1JA 4Y32A 1QJAA 4JDDA 5LVZA 3SMKA 4Y3BA 1O9CA 3MHRA 4W8JA 5D3FA 2O8PA 3UALA 4FL5A 3CQCA 5D2DA 5LHOA 1QJBA 4DHUA 3CQGA 5LX2A 3EB7A 1JI6A 3P1QA 1W99A 4ZDRA 3UBWA 4DX0A 3EFZA 3X0UA 3M50A 4N7GA 1O9FA 2C1NA 1YZ5A 3M51A 5J31A 4IEAA 1URJA 3I4RA 4HKCA 4DHRA 4Y5IA 4F7RA 4ARXA 1A4OA 4DNKA 5BTVA 3SMOA 3IQJA 3SP5A 4E2EA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4WRQ A;  3SMN A;  4DHS A;  3P1N A;  4N7Y A;  4DHQ A;  2BR9 A;  3LW1 A;  4JC3 A;  3SPR A;  1O9E A;  1O9D A;  5EXA A;  3O8I A;  4DAT A;  2C23 A;  5LU1 A;  5IQP A;  4DHM A;  4IHL A;  2O98 A;  4GNT A;  4DHN A;  2O02 A;  4DHO A;  4DHP A;  4ZQ0 A;  3IQU A;  1IB1 A;  2C74 A;  1A37 A;  3IQV A;  3CU8 A;  4DAU A;  3T0M A;  4J6S A;  5BY9 A;  4FR3 A;  2WH0 A;  2C63 A;  3E6Y A;  4O46 A;  4DHT A;  2B05 A;  3P1O A;  5EWZ A;  3SMM A;  5HF3 A;  5F74 A;  3RDH A;  3P1P A;  4FJ3 A;  1A38 A;  3AXY C;  3NKX A;  5LU2 A;  2BQ0 A;  3UZD A;  4BG6 A;  1YWT A;  2NPM A;  3T0L A;  5D3E A;  3P1R A;  4N84 A;  3UX0 A;  3U9X A;  4QLI A;  2V7D A;  3P1S A;  3SML A;  2BTP A;  2C1J A;  4Y32 A;  1QJA A;  4JDD A;  5LVZ A;  3SMK A;  4Y3B A;  1O9C A;  3MHR A;  5D3F A;  3UAL A;  2O8P A;  4FL5 A;  5D2D A;  5LHO A;  1QJB A;  4DHU A;  5LX2 A;  4ZDR A;  3P1Q A;  3UBW A;  4DX0 A;  3EFZ A;  3M50 A;  4N7G A;  1O9F A;  2C1N A;  1YZ5 A;  3M51 A;  5J31 A;  4IEA A;  4HKC A;  4DHR A;  4Y5I A;  4F7R A;  1A4O A;  4DNK A;  5BTV A;  3SMO A;  3IQJ A;  3SP5 A;  4E2E A; 
#chains in the Genus database with same CATH topology
 2C9K A;  4WRQ A;  3SMN A;  4DHS A;  4MOA A;  3P1N A;  4ARY A;  4N7Y A;  4DHQ A;  2BR9 A;  3LW1 A;  4JC3 A;  3SPR A;  1O9E A;  1O9D A;  5EXA A;  3O8I A;  4DAT A;  2C23 A;  5LU1 A;  5IQP A;  4DHM A;  1CIY A;  4IHL A;  2O98 A;  4QX0 A;  4GNT A;  4DHN A;  2O02 A;  4DHO A;  1S2X A;  4QX3 A;  4DHP A;  4ZQ0 A;  3IQU A;  1IB1 A;  2C74 A;  1A37 A;  3IQV A;  3CU8 A;  4DAU A;  3T0M A;  4J6S A;  1DLC A;  4QX2 A;  5BY9 A;  4FR3 A;  2WH0 A;  2C63 A;  3E6Y A;  4O46 A;  4DHT A;  2B05 A;  3P1O A;  5EWZ A;  3SMM A;  5HF3 A;  5F74 A;  3RDH A;  3P1P A;  4FJ3 A;  1A38 A;  3AXY C;  3NKX A;  5LU2 A;  2BQ0 A;  3UZD A;  4BG6 A;  4D8M A;  1YWT A;  1I5P A;  2NPM A;  3T0L A;  5D3E A;  3P1R A;  4N84 A;  3UX0 A;  4QX1 A;  3U9X A;  4QLI A;  2V7D A;  3ZHE B;  3P1S A;  3SML A;  2BTP A;  2C1J A;  4Y32 A;  1QJA A;  4JDD A;  5LVZ A;  3SMK A;  4Y3B A;  1O9C A;  3MHR A;  4W8J A;  5D3F A;  2O8P A;  3UAL A;  4FL5 A;  3CQC A;  5D2D A;  5LHO A;  1QJB A;  4DHU A;  3CQG A;  5LX2 A;  3EB7 A;  1JI6 A;  3P1Q A;  1W99 A;  4ZDR A;  3UBW A;  4DX0 A;  3EFZ A;  3X0U A;  3M50 A;  4N7G A;  1O9F A;  2C1N A;  1YZ5 A;  3M51 A;  5J31 A;  4IEA A;  1URJ A;  3I4R A;  4HKC A;  4DHR A;  4Y5I A;  4F7R A;  4ARX A;  1A4O A;  4DNK A;  5BTV A;  3SMO A;  3IQJ A;  3SP5 A;  4E2E A; 
#chains in the Genus database with same CATH homology
 4WRQ A;  3SMN A;  4DHS A;  3P1N A;  4N7Y A;  4DHQ A;  2BR9 A;  3LW1 A;  4JC3 A;  3SPR A;  1O9E A;  1O9D A;  5EXA A;  3O8I A;  4DAT A;  2C23 A;  5LU1 A;  5IQP A;  4DHM A;  4IHL A;  2O98 A;  4GNT A;  4DHN A;  2O02 A;  4DHO A;  4DHP A;  4ZQ0 A;  3IQU A;  1IB1 A;  2C74 A;  1A37 A;  3IQV A;  3CU8 A;  4DAU A;  3T0M A;  4J6S A;  5BY9 A;  4FR3 A;  2WH0 A;  2C63 A;  3E6Y A;  4O46 A;  4DHT A;  2B05 A;  3P1O A;  5EWZ A;  3SMM A;  5HF3 A;  5F74 A;  3RDH A;  3P1P A;  4FJ3 A;  1A38 A;  3AXY C;  3NKX A;  5LU2 A;  2BQ0 A;  3UZD A;  4BG6 A;  1YWT A;  2NPM A;  3T0L A;  5D3E A;  3P1R A;  4N84 A;  3UX0 A;  3U9X A;  4QLI A;  2V7D A;  3P1S A;  3SML A;  2BTP A;  2C1J A;  4Y32 A;  1QJA A;  4JDD A;  5LVZ A;  3SMK A;  4Y3B A;  1O9C A;  3MHR A;  5D3F A;  3UAL A;  2O8P A;  4FL5 A;  5D2D A;  5LHO A;  1QJB A;  4DHU A;  5LX2 A;  4ZDR A;  3P1Q A;  3UBW A;  4DX0 A;  3EFZ A;  3M50 A;  4N7G A;  1O9F A;  2C1N A;  1YZ5 A;  3M51 A;  5J31 A;  4IEA A;  4HKC A;  4DHR A;  4Y5I A;  4F7R A;  1A4O A;  4DNK A;  5BTV A;  3SMO A;  3IQJ A;  3SP5 A;  4E2E A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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3SMLA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations