3SMNA

Crystal structure of human 14-3-3 sigma c38n/n166h in complex with task-3 peptide and stabilizer fusicoccin a-thf
Total Genus 102
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
236
structure length
236
Chain Sequence
GAMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSNEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTHPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface.
pubmed doi rcsb
molecule tags Peptide binding protein
source organism Homo sapiens
molecule keywords 14-3-3 protein sigma
total genus 102
structure length 236
sequence length 236
ec nomenclature
pdb deposition date 2011-06-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 3smnA00
4BG6A 5LHOA 3IQJA 4Y3BA 3P1PA 4DHRA 3LW1A 3RDHA 3SMKA 2WH0A 4DHSA 1A37A 2O02A 5D3FA 4J6SA 1O9FA 4DHNA 3EFZA 3SPRA 1O9EA 4DHMA 3P1NA 5HF3A 4DATA 5BTVA 4FL5A 3P1OA 3P1QA 2C74A 3MHRA 2V7DA 3SMLA 5EXAA 3E6YA 4ZQ0A 5BY9A 1YZ5A 3U9XA 4DAUA 4Y5IA 4F7RA 5EWZA 5LX2A 1O9DA 2B05A 3T0MA 5J31A 2O8PA 3UALA 3M51A 4N7GA 5LU1A 2BTPA 3IQVA 5D3EA 4FR3A 2C1NA 4DX0A 4IHLA 4DHOA 5LVZA 4IEAA 3P1RA 1A38A 3UZDA 2NPMA 4HKCA 3IQUA 4WRQA 3SP5A 3CU8A 4DHQA 3M50A 4JDDA 1QJAA 4DHUA 3NKXA 4N84A 4DHPA 4DHTA 3AXYC 4ZDRA 3UBWA 2BQ0A 3SMMA 4JC3A 4FJ3A 3SMOA 3T0LA 4N7YA 2O98A 1A4OA 5F74A 2C1JA 4QLIA 2BR9A 3UX0A 5D2DA 1QJBA 5LU2A 5IQPA 3P1SA 2C63A 1IB1A 4DNKA 1YWTA 4Y32A 4O46A 3SMNA 4GNTA 2C23A 4E2EA 1O9CA 3O8IA
chains in the Genus database with same CATH superfamily
3X0UA 4QX2A 4BG6A 5LHOA 3IQJA 4Y3BA 3P1PA 4DHRA 3LW1A 3RDHA 3SMKA 2WH0A 4DHSA 1A37A 2O02A 5D3FA 4J6SA 1O9FA 4DHNA 3EFZA 3SPRA 1O9EA 4DHMA 3P1NA 4QX1A 1URJA 5HF3A 4DATA 5BTVA 4FL5A 3P1OA 4ARYA 3P1QA 2C74A 3MHRA 2V7DA 3ZHEB 3SMLA 5EXAA 3E6YA 4ZQ0A 5BY9A 3CQCA 1YZ5A 3U9XA 4DAUA 4Y5IA 4F7RA 2C9KA 5EWZA 5LX2A 1O9DA 2B05A 3T0MA 5J31A 2O8PA 3UALA 3M51A 4N7GA 5LU1A 2BTPA 3IQVA 5D3EA 3I4RA 4FR3A 2C1NA 4DX0A 1CIYA 4IHLA 4DHOA 5LVZA 4IEAA 3P1RA 1A38A 1I5PA 1W99A 3UZDA 2NPMA 4QX3A 4HKCA 4MOAA 3IQUA 4WRQA 3SP5A 3CU8A 4DHQA 3M50A 4JDDA 1QJAA 4DHUA 3NKXA 1DLCA 4N84A 4DHPA 4DHTA 3AXYC 4ZDRA 3UBWA 4W8JA 2BQ0A 3SMMA 4D8MA 4JC3A 4FJ3A 3SMOA 4ARXA 1JI6A 3T0LA 4N7YA 2O98A 1A4OA 5F74A 2C1JA 4QLIA 2BR9A 3UX0A 5D2DA 1QJBA 5LU2A 5IQPA 3P1SA 2C63A 1IB1A 4DNKA 1YWTA 4Y32A 4O46A 3SMNA 4GNTA 2C23A 4E2EA 3EB7A 1O9CA 1S2XA 3O8IA 4QX0A 3CQGA
chains in the Genus database with same CATH topology
4BG6A 5LHOA 3IQJA 4Y3BA 3P1PA 4DHRA 3LW1A 3RDHA 3SMKA 2WH0A 4DHSA 1A37A 2O02A 5D3FA 4J6SA 1O9FA 4DHNA 3EFZA 3SPRA 1O9EA 4DHMA 3P1NA 5HF3A 4DATA 5BTVA 4FL5A 3P1OA 3P1QA 2C74A 3MHRA 2V7DA 3SMLA 5EXAA 3E6YA 4ZQ0A 5BY9A 1YZ5A 3U9XA 4DAUA 4Y5IA 4F7RA 5EWZA 5LX2A 1O9DA 2B05A 3T0MA 5J31A 2O8PA 3UALA 3M51A 4N7GA 5LU1A 2BTPA 3IQVA 5D3EA 4FR3A 2C1NA 4DX0A 4IHLA 4DHOA 5LVZA 4IEAA 3P1RA 1A38A 3UZDA 2NPMA 4HKCA 3IQUA 4WRQA 3SP5A 3CU8A 4DHQA 3M50A 4JDDA 1QJAA 4DHUA 3NKXA 4N84A 4DHPA 4DHTA 3AXYC 4ZDRA 3UBWA 2BQ0A 3SMMA 4JC3A 4FJ3A 3SMOA 3T0LA 4N7YA 2O98A 1A4OA 5F74A 2C1JA 4QLIA 2BR9A 3UX0A 5D2DA 1QJBA 5LU2A 5IQPA 3P1SA 2C63A 1IB1A 4DNKA 1YWTA 4Y32A 4O46A 3SMNA 4GNTA 2C23A 4E2EA 1O9CA 3O8IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BG6 A;  5LHO A;  3IQJ A;  4Y3B A;  3P1P A;  4DHR A;  3LW1 A;  3RDH A;  3SMK A;  2WH0 A;  4DHS A;  1A37 A;  2O02 A;  5D3F A;  4J6S A;  1O9F A;  4DHN A;  3EFZ A;  3SPR A;  1O9E A;  4DHM A;  3P1N A;  5HF3 A;  4DAT A;  5BTV A;  4FL5 A;  3P1O A;  3P1Q A;  2C74 A;  3MHR A;  2V7D A;  3SML A;  5EXA A;  3E6Y A;  4ZQ0 A;  5BY9 A;  1YZ5 A;  3U9X A;  4DAU A;  4Y5I A;  4F7R A;  5EWZ A;  5LX2 A;  1O9D A;  2B05 A;  3T0M A;  5J31 A;  2O8P A;  3UAL A;  3M51 A;  4N7G A;  5LU1 A;  2BTP A;  3IQV A;  5D3E A;  4FR3 A;  2C1N A;  4DX0 A;  4IHL A;  4DHO A;  5LVZ A;  4IEA A;  3P1R A;  1A38 A;  3UZD A;  2NPM A;  4HKC A;  3IQU A;  4WRQ A;  3SP5 A;  3CU8 A;  4DHQ A;  3M50 A;  4JDD A;  1QJA A;  4DHU A;  3NKX A;  4N84 A;  4DHP A;  4DHT A;  3AXY C;  4ZDR A;  3UBW A;  2BQ0 A;  3SMM A;  4JC3 A;  4FJ3 A;  3SMO A;  3T0L A;  4N7Y A;  2O98 A;  1A4O A;  5F74 A;  2C1J A;  4QLI A;  2BR9 A;  3UX0 A;  5D2D A;  1QJB A;  5LU2 A;  5IQP A;  3P1S A;  2C63 A;  1IB1 A;  4DNK A;  1YWT A;  4Y32 A;  4O46 A;  3SMN A;  4GNT A;  2C23 A;  4E2E A;  1O9C A;  3O8I A; 
#chains in the Genus database with same CATH topology
 3X0U A;  4QX2 A;  4BG6 A;  5LHO A;  3IQJ A;  4Y3B A;  3P1P A;  4DHR A;  3LW1 A;  3RDH A;  3SMK A;  2WH0 A;  4DHS A;  1A37 A;  2O02 A;  5D3F A;  4J6S A;  1O9F A;  4DHN A;  3EFZ A;  3SPR A;  1O9E A;  4DHM A;  3P1N A;  4QX1 A;  1URJ A;  5HF3 A;  4DAT A;  5BTV A;  4FL5 A;  3P1O A;  4ARY A;  3P1Q A;  2C74 A;  3MHR A;  2V7D A;  3ZHE B;  3SML A;  5EXA A;  3E6Y A;  4ZQ0 A;  5BY9 A;  3CQC A;  1YZ5 A;  3U9X A;  4DAU A;  4Y5I A;  4F7R A;  2C9K A;  5EWZ A;  5LX2 A;  1O9D A;  2B05 A;  3T0M A;  5J31 A;  2O8P A;  3UAL A;  3M51 A;  4N7G A;  5LU1 A;  2BTP A;  3IQV A;  5D3E A;  3I4R A;  4FR3 A;  2C1N A;  4DX0 A;  1CIY A;  4IHL A;  4DHO A;  5LVZ A;  4IEA A;  3P1R A;  1A38 A;  1I5P A;  1W99 A;  3UZD A;  2NPM A;  4QX3 A;  4HKC A;  4MOA A;  3IQU A;  4WRQ A;  3SP5 A;  3CU8 A;  4DHQ A;  3M50 A;  4JDD A;  1QJA A;  4DHU A;  3NKX A;  1DLC A;  4N84 A;  4DHP A;  4DHT A;  3AXY C;  4ZDR A;  3UBW A;  4W8J A;  2BQ0 A;  3SMM A;  4D8M A;  4JC3 A;  4FJ3 A;  3SMO A;  4ARX A;  1JI6 A;  3T0L A;  4N7Y A;  2O98 A;  1A4O A;  5F74 A;  2C1J A;  4QLI A;  2BR9 A;  3UX0 A;  5D2D A;  1QJB A;  5LU2 A;  5IQP A;  3P1S A;  2C63 A;  1IB1 A;  4DNK A;  1YWT A;  4Y32 A;  4O46 A;  3SMN A;  4GNT A;  2C23 A;  4E2E A;  3EB7 A;  1O9C A;  1S2X A;  3O8I A;  4QX0 A;  3CQG A; 
#chains in the Genus database with same CATH homology
 4BG6 A;  5LHO A;  3IQJ A;  4Y3B A;  3P1P A;  4DHR A;  3LW1 A;  3RDH A;  3SMK A;  2WH0 A;  4DHS A;  1A37 A;  2O02 A;  5D3F A;  4J6S A;  1O9F A;  4DHN A;  3EFZ A;  3SPR A;  1O9E A;  4DHM A;  3P1N A;  5HF3 A;  4DAT A;  5BTV A;  4FL5 A;  3P1O A;  3P1Q A;  2C74 A;  3MHR A;  2V7D A;  3SML A;  5EXA A;  3E6Y A;  4ZQ0 A;  5BY9 A;  1YZ5 A;  3U9X A;  4DAU A;  4Y5I A;  4F7R A;  5EWZ A;  5LX2 A;  1O9D A;  2B05 A;  3T0M A;  5J31 A;  2O8P A;  3UAL A;  3M51 A;  4N7G A;  5LU1 A;  2BTP A;  3IQV A;  5D3E A;  4FR3 A;  2C1N A;  4DX0 A;  4IHL A;  4DHO A;  5LVZ A;  4IEA A;  3P1R A;  1A38 A;  3UZD A;  2NPM A;  4HKC A;  3IQU A;  4WRQ A;  3SP5 A;  3CU8 A;  4DHQ A;  3M50 A;  4JDD A;  1QJA A;  4DHU A;  3NKX A;  4N84 A;  4DHP A;  4DHT A;  3AXY C;  4ZDR A;  3UBW A;  2BQ0 A;  3SMM A;  4JC3 A;  4FJ3 A;  3SMO A;  3T0L A;  4N7Y A;  2O98 A;  1A4O A;  5F74 A;  2C1J A;  4QLI A;  2BR9 A;  3UX0 A;  5D2D A;  1QJB A;  5LU2 A;  5IQP A;  3P1S A;  2C63 A;  1IB1 A;  4DNK A;  1YWT A;  4Y32 A;  4O46 A;  3SMN A;  4GNT A;  2C23 A;  4E2E A;  1O9C A;  3O8I A; 
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