3CC4W

Co-crystal structure of anisomycin bound to the 50s ribosomal subunit
Total Genus 46
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 46
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3cc4W02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 3cc4W01
1W2BV 3G6EW 1VQNW 1K9MX 3CCQW 3CC2W 1VQ5W 3PIPW 5JVHW 3CD6W 4WFNW 5GAHa 2ZJPW 3CMEW 4UY8Z 1YJNW 3CCLW 3J7ZZ 3PIOW 5HL7W 3CC7W 5JVGW 1Q82X 5GADa 3CCUW 2OTLW 3CCSW 5DM6W 3OW2V 2OTJW 1NJIX 1KQSV 4IO9W 3I56W 2QA4W 3CPWV 5DM7W 1VQ4W 1Q7YX 3I55W 1QVGV 3G71W 1KD1X 4U67W 1S72W 1VQKW 3CC4W 1Q86X 2ZJRW 4IOCW 1VQ8W 1YITW 1N8RX 1VQOW 4IOAW 2QEXW 1K8AX 2ZJQW 1BXYA 4WFAW 3G4SW 1KC8X 4WF9W 3CMAW 3CXCV 4WCEW 3CCMW 1JJ2V 1YI2W 1VQ7W 3CCEW 1YJ9W 1M90X 3CCJW 3CCRW 1YHQW 4WFBW 1VQLW 1YJWW 1YIJW 1M1KX 5GAGa 1VQMW 1VQPW 1VQ6W 1K73X 3CF5W 3DLLW 3CCVW 1Q81X 5GAEa 1QVFV 1VQ9W
chains in the Genus database with same CATH superfamily
1W2BV 3O2HA 4BL3A 3ZG0A 3ZFZA 3G6EW 1VQNW 3GQ0A 3W7UA 1K9MX 3CCQW 3CC2W 3D3IA 1VQ5W 4YJXA 3PIPW 1CTFA 4CPKA 5JVHW 3CD6W 3O2BA 4WFNW 1MBVB 5GAHa 3W7SA 4YKAA 3DNJA 2ZJPW 3CMEW 4YJMA 5CA3A 4UY8Z 1MWRA 1YJNW 3GQ1A 3CCLW 3J7ZZ 1DD3A 3PIOW 5HL7W 3CC7W 3ZG5A 5JVGW 1Q82X 5GADa 3CCUW 2OTLW 3CCSW 5DM6W 3OW2V 2WA9A 2OTJW 1NJIX 5GW7A 1KQSV 1RQSA 4IO9W 3I56W 5M18A 2QA4W 3CPWV 5DM7W 1VQ4W 1Q7YX 1DD4A 3I55W 1QVGV 3G71W 3W7WA 1KD1X 1LZWA 4CJNA 4U67W 1S72W 1MWTA 1R6QC 1VQKW 3W7TA 3CC4W 1Q86X 2ZJRW 3G3PA 4IOCW 1VQ8W 1YITW 1N8RX 1VQOW 4IOAW 1MG9A 2QEXW 1K8AX 2ZJQW 3O1FA 1BXYA 4WFAW 3G4SW 1KC8X 4WF9W 1MBXC 1R6OC 3CMAW 3CXCV 1MWUA 4WCEW 3CCMW 1JJ2V 1YI2W 1VQ7W 3CCEW 1RQUA 1YJ9W 1M90X 2WA8A 1MBUC 3CCJW 3CCRW 1YHQW 4WFBW 3W7XA 1VQLW 4BL2A 1YJWW 4C1NA 2W9RA 1YIJW 3O2OA 1M1KX 5GAGa 1MWSA 1VQMW 4DKIA 1VQQA 1VQPW 3GW1A 1VQ6W 1K73X 3G19A 3CF5W 3DLLW 3CCVW 1Q81X 5GAEa 3G1BA 1QVFV 3O1FB 1VQ9W 1RQVA 5M19A 5M1AA
chains in the Genus database with same CATH topology
1W2BV 3G6EW 1VQNW 1K9MX 3CCQW 3CC2W 1VQ5W 3PIPW 5JVHW 3CD6W 4WFNW 5GAHa 2ZJPW 3CMEW 4UY8Z 1YJNW 3CCLW 3J7ZZ 3PIOW 5HL7W 3CC7W 5JVGW 1Q82X 5GADa 3CCUW 2OTLW 3CCSW 5DM6W 3OW2V 2OTJW 1NJIX 1KQSV 4IO9W 3I56W 2QA4W 3CPWV 5DM7W 1VQ4W 1Q7YX 3I55W 1QVGV 3G71W 1KD1X 4U67W 1S72W 1VQKW 3CC4W 1Q86X 2ZJRW 4IOCW 1VQ8W 1YITW 1N8RX 1VQOW 4IOAW 2QEXW 1K8AX 2ZJQW 1BXYA 4WFAW 3G4SW 1KC8X 4WF9W 3CMAW 3CXCV 4WCEW 3CCMW 1JJ2V 1YI2W 1VQ7W 3CCEW 1YJ9W 1M90X 3CCJW 3CCRW 1YHQW 4WFBW 1VQLW 1YJWW 4C1NA 1YIJW 1M1KX 5GAGa 1VQMW 1VQPW 1VQ6W 1K73X 3CF5W 3DLLW 3CCVW 1Q81X 5GAEa 1QVFV 1VQ9W
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1W2B V;  3G6E W;  1VQN W;  1K9M X;  3CCQ W;  3CC2 W;  1VQ5 W;  3PIP W;  5JVH W;  3CD6 W;  4WFN W;  5GAH a;  2ZJP W;  3CME W;  4UY8 Z;  1YJN W;  3CCL W;  3J7Z Z;  3PIO W;  5HL7 W;  3CC7 W;  5JVG W;  1Q82 X;  5GAD a;  3CCU W;  2OTL W;  3CCS W;  5DM6 W;  3OW2 V;  2OTJ W;  1NJI X;  1KQS V;  4IO9 W;  3I56 W;  2QA4 W;  3CPW V;  5DM7 W;  1VQ4 W;  1Q7Y X;  3I55 W;  1QVG V;  3G71 W;  1KD1 X;  4U67 W;  1S72 W;  1VQK W;  3CC4 W;  1Q86 X;  2ZJR W;  4IOC W;  1VQ8 W;  1YIT W;  1N8R X;  1VQO W;  4IOA W;  2QEX W;  1K8A X;  2ZJQ W;  1BXY A;  4WFA W;  3G4S W;  1KC8 X;  4WF9 W;  3CMA W;  3CXC V;  4WCE W;  3CCM W;  1JJ2 V;  1YI2 W;  1VQ7 W;  3CCE W;  1YJ9 W;  1M90 X;  3CCJ W;  3CCR W;  1YHQ W;  4WFB W;  1VQL W;  1YJW W;  1YIJ W;  1M1K X;  5GAG a;  1VQM W;  1VQP W;  1VQ6 W;  1K73 X;  3CF5 W;  3DLL W;  3CCV W;  1Q81 X;  5GAE a;  1QVF V;  1VQ9 W; 
#chains in the Genus database with same CATH topology
 1W2B V;  3O2H A;  4BL3 A;  3ZG0 A;  3ZFZ A;  3G6E W;  1VQN W;  3GQ0 A;  3W7U A;  1K9M X;  3CCQ W;  3CC2 W;  3D3I A;  1VQ5 W;  4YJX A;  3PIP W;  1CTF A;  4CPK A;  5JVH W;  3CD6 W;  3O2B A;  4WFN W;  1MBV B;  5GAH a;  3W7S A;  4YKA A;  3DNJ A;  2ZJP W;  3CME W;  4YJM A;  5CA3 A;  4UY8 Z;  1MWR A;  1YJN W;  3GQ1 A;  3CCL W;  3J7Z Z;  1DD3 A;  3PIO W;  5HL7 W;  3CC7 W;  3ZG5 A;  5JVG W;  1Q82 X;  5GAD a;  3CCU W;  2OTL W;  3CCS W;  5DM6 W;  3OW2 V;  2WA9 A;  2OTJ W;  1NJI X;  5GW7 A;  1KQS V;  1RQS A;  4IO9 W;  3I56 W;  5M18 A;  2QA4 W;  3CPW V;  5DM7 W;  1VQ4 W;  1Q7Y X;  1DD4 A;  3I55 W;  1QVG V;  3G71 W;  3W7W A;  1KD1 X;  1LZW A;  4CJN A;  4U67 W;  1S72 W;  1MWT A;  1R6Q C;  1VQK W;  3W7T A;  3CC4 W;  1Q86 X;  2ZJR W;  3G3P A;  4IOC W;  1VQ8 W;  1YIT W;  1N8R X;  1VQO W;  4IOA W;  1MG9 A;  2QEX W;  1K8A X;  2ZJQ W;  3O1F A;  1BXY A;  4WFA W;  3G4S W;  1KC8 X;  4WF9 W;  1MBX C;  1R6O C;  3CMA W;  3CXC V;  1MWU A;  4WCE W;  3CCM W;  1JJ2 V;  1YI2 W;  1VQ7 W;  3CCE W;  1RQU A;  1YJ9 W;  1M90 X;  2WA8 A;  1MBU C;  3CCJ W;  3CCR W;  1YHQ W;  4WFB W;  3W7X A;  1VQL W;  4BL2 A;  1YJW W;  4C1N A;  2W9R A;  1YIJ W;  3O2O A;  1M1K X;  5GAG a;  1MWS A;  1VQM W;  4DKI A;  1VQQ A;  1VQP W;  3GW1 A;  1VQ6 W;  1K73 X;  3G19 A;  3CF5 W;  3DLL W;  3CCV W;  1Q81 X;  5GAE a;  3G1B A;  1QVF V;  3O1F B;  1VQ9 W;  1RQV A;  5M19 A;  5M1A A; 
#chains in the Genus database with same CATH homology
 1W2B V;  3G6E W;  1VQN W;  1K9M X;  3CCQ W;  3CC2 W;  1VQ5 W;  3PIP W;  5JVH W;  3CD6 W;  4WFN W;  5GAH a;  2ZJP W;  3CME W;  4UY8 Z;  1YJN W;  3CCL W;  3J7Z Z;  3PIO W;  5HL7 W;  3CC7 W;  5JVG W;  1Q82 X;  5GAD a;  3CCU W;  2OTL W;  3CCS W;  5DM6 W;  3OW2 V;  2OTJ W;  1NJI X;  1KQS V;  4IO9 W;  3I56 W;  2QA4 W;  3CPW V;  5DM7 W;  1VQ4 W;  1Q7Y X;  3I55 W;  1QVG V;  3G71 W;  1KD1 X;  4U67 W;  1S72 W;  1VQK W;  3CC4 W;  1Q86 X;  2ZJR W;  4IOC W;  1VQ8 W;  1YIT W;  1N8R X;  1VQO W;  4IOA W;  2QEX W;  1K8A X;  2ZJQ W;  1BXY A;  4WFA W;  3G4S W;  1KC8 X;  4WF9 W;  3CMA W;  3CXC V;  4WCE W;  3CCM W;  1JJ2 V;  1YI2 W;  1VQ7 W;  3CCE W;  1YJ9 W;  1M90 X;  3CCJ W;  3CCR W;  1YHQ W;  4WFB W;  1VQL W;  1YJW W;  4C1N A;  1YIJ W;  1M1K X;  5GAG a;  1VQM W;  1VQP W;  1VQ6 W;  1K73 X;  3CF5 W;  3DLL W;  3CCV W;  1Q81 X;  5GAE a;  1QVF V;  1VQ9 W; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...