3CCEW

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535a
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 47
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3cceW02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 3cceW01
3PIOW 1YJWW 3CF5W 3CCEW 1BXYA 1YJNW 3CC4W 1K9MX 1Q81X 3CCRW 1JJ2V 3CCVW 1M1KX 1VQMW 4IO9W 4IOCW 1VQOW 1YHQW 5GADa 1S72W 4WF9W 1KC8X 1VQ5W 5GAEa 1YI2W 2ZJQW 3CCQW 2QA4W 3CCUW 3CCJW 4WFAW 1Q82X 3CC2W 3CCMW 3I56W 3OW2V 3CCSW 3CD6W 5HL7W 4WFNW 1YITW 3CC7W 2ZJRW 4IOAW 1NJIX 1VQNW 3PIPW 5DM6W 2QEXW 1QVFV 3J7ZZ 1W2BV 4UY8Z 1VQ8W 5JVHW 1YJ9W 3CPWV 3G4SW 1VQ4W 1K8AX 1Q86X 5JVGW 5GAHa 3CXCV 3CMAW 3CCLW 3CMEW 2OTLW 1VQ7W 1VQ9W 3DLLW 1N8RX 2OTJW 3I55W 4U67W 5DM7W 3G6EW 1VQPW 1QVGV 4WFBW 1KD1X 1KQSV 3G71W 1YIJW 5GAGa 4WCEW 1VQ6W 1K73X 2ZJPW 1M90X 1Q7YX 1VQKW 1VQLW
chains in the Genus database with same CATH superfamily
3PIOW 1YJWW 3CF5W 3O1FA 3W7SA 4CPKA 3CCEW 1BXYA 1YJNW 3CC4W 3W7WA 1K9MX 1Q81X 3CCRW 3GQ0A 4CJNA 3G19A 3W7UA 1JJ2V 3CCVW 1M1KX 1VQMW 4IO9W 3D3IA 1MWUA 3W7TA 4IOCW 1VQOW 1YHQW 2WA9A 5GADa 1S72W 4WF9W 1KC8X 3GW1A 1VQ5W 5GAEa 1YI2W 1MWTA 3O1FB 2ZJQW 3ZG0A 3CCQW 2QA4W 3CCUW 4DKIA 3CCJW 3DNJA 4WFAW 1DD3A 1MWSA 4YJMA 5M18A 1Q82X 3CC2W 3CCMW 3I56W 3OW2V 3ZG5A 3CCSW 3GQ1A 3CD6W 5HL7W 4WFNW 1YITW 3CC7W 2ZJRW 5GW7A 4IOAW 1NJIX 1VQNW 3O2HA 3PIPW 3O2BA 5DM6W 2QEXW 1LZWA 1RQUA 3G1BA 1QVFV 3J7ZZ 1RQSA 5M1AA 3ZFZA 1W2BV 1R6QC 1RQVA 4UY8Z 4YKAA 1VQ8W 5M19A 5JVHW 1CTFA 4BL3A 1YJ9W 1MWRA 3CPWV 3O2OA 3G4SW 1VQ4W 1VQQA 1K8AX 1Q86X 5JVGW 5GAHa 3CXCV 3CMAW 3CCLW 3CMEW 2OTLW 1VQ7W 1VQ9W 1R6OC 1MBXC 3DLLW 1N8RX 2OTJW 3I55W 4U67W 5DM7W 3G6EW 1MBUC 1VQPW 5CA3A 1QVGV 4WFBW 2W9RA 1KD1X 1KQSV 3G71W 3G3PA 1YIJW 5GAGa 4BL2A 4WCEW 3W7XA 1MBVB 1VQ6W 2WA8A 1K73X 1MG9A 4YJXA 4C1NA 2ZJPW 1DD4A 1M90X 1Q7YX 1VQKW 1VQLW
chains in the Genus database with same CATH topology
3PIOW 1YJWW 3CF5W 3CCEW 1BXYA 1YJNW 3CC4W 1K9MX 1Q81X 3CCRW 1JJ2V 3CCVW 1M1KX 1VQMW 4IO9W 4IOCW 1VQOW 1YHQW 5GADa 1S72W 4WF9W 1KC8X 1VQ5W 5GAEa 1YI2W 2ZJQW 3CCQW 2QA4W 3CCUW 3CCJW 4WFAW 1Q82X 3CC2W 3CCMW 3I56W 3OW2V 3CCSW 4WFNW 3CD6W 5HL7W 1YITW 3CC7W 2ZJRW 4IOAW 1NJIX 1VQNW 3PIPW 5DM6W 2QEXW 1QVFV 3J7ZZ 1W2BV 4UY8Z 1VQ8W 5JVHW 1YJ9W 3CPWV 3G4SW 1VQ4W 1K8AX 1Q86X 5JVGW 5GAHa 3CXCV 3CMAW 3CCLW 3CMEW 2OTLW 1VQ7W 1VQ9W 3DLLW 1N8RX 2OTJW 3I55W 4U67W 5DM7W 3G6EW 1VQPW 1QVGV 4WFBW 1KD1X 1KQSV 3G71W 1YIJW 5GAGa 4WCEW 1VQ6W 1K73X 4C1NA 2ZJPW 1M90X 1Q7YX 1VQKW 1VQLW
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PIO W;  1YJW W;  3CF5 W;  3CCE W;  1BXY A;  1YJN W;  3CC4 W;  1K9M X;  1Q81 X;  3CCR W;  1JJ2 V;  3CCV W;  1M1K X;  1VQM W;  4IO9 W;  4IOC W;  1VQO W;  1YHQ W;  5GAD a;  1S72 W;  4WF9 W;  1KC8 X;  1VQ5 W;  5GAE a;  1YI2 W;  2ZJQ W;  3CCQ W;  2QA4 W;  3CCU W;  3CCJ W;  4WFA W;  1Q82 X;  3CC2 W;  3CCM W;  3I56 W;  3OW2 V;  3CCS W;  3CD6 W;  5HL7 W;  4WFN W;  1YIT W;  3CC7 W;  2ZJR W;  4IOA W;  1NJI X;  1VQN W;  3PIP W;  5DM6 W;  2QEX W;  1QVF V;  3J7Z Z;  1W2B V;  4UY8 Z;  1VQ8 W;  5JVH W;  1YJ9 W;  3CPW V;  3G4S W;  1VQ4 W;  1K8A X;  1Q86 X;  5JVG W;  5GAH a;  3CXC V;  3CMA W;  3CCL W;  3CME W;  2OTL W;  1VQ7 W;  1VQ9 W;  3DLL W;  1N8R X;  2OTJ W;  3I55 W;  4U67 W;  5DM7 W;  3G6E W;  1VQP W;  1QVG V;  4WFB W;  1KD1 X;  1KQS V;  3G71 W;  1YIJ W;  5GAG a;  4WCE W;  1VQ6 W;  1K73 X;  2ZJP W;  1M90 X;  1Q7Y X;  1VQK W;  1VQL W; 
#chains in the Genus database with same CATH topology
 3PIO W;  1YJW W;  3CF5 W;  3O1F A;  3W7S A;  4CPK A;  3CCE W;  1BXY A;  1YJN W;  3CC4 W;  3W7W A;  1K9M X;  1Q81 X;  3CCR W;  3GQ0 A;  4CJN A;  3G19 A;  3W7U A;  1JJ2 V;  3CCV W;  1M1K X;  1VQM W;  4IO9 W;  3D3I A;  1MWU A;  3W7T A;  4IOC W;  1VQO W;  1YHQ W;  2WA9 A;  5GAD a;  1S72 W;  4WF9 W;  1KC8 X;  3GW1 A;  1VQ5 W;  5GAE a;  1YI2 W;  1MWT A;  3O1F B;  2ZJQ W;  3ZG0 A;  3CCQ W;  2QA4 W;  3CCU W;  4DKI A;  3CCJ W;  3DNJ A;  4WFA W;  1DD3 A;  1MWS A;  4YJM A;  5M18 A;  1Q82 X;  3CC2 W;  3CCM W;  3I56 W;  3OW2 V;  3ZG5 A;  3CCS W;  3GQ1 A;  3CD6 W;  5HL7 W;  4WFN W;  1YIT W;  3CC7 W;  2ZJR W;  5GW7 A;  4IOA W;  1NJI X;  1VQN W;  3O2H A;  3PIP W;  3O2B A;  5DM6 W;  2QEX W;  1LZW A;  1RQU A;  3G1B A;  1QVF V;  3J7Z Z;  1RQS A;  5M1A A;  3ZFZ A;  1W2B V;  1R6Q C;  1RQV A;  4UY8 Z;  4YKA A;  1VQ8 W;  5M19 A;  5JVH W;  1CTF A;  4BL3 A;  1YJ9 W;  1MWR A;  3CPW V;  3O2O A;  3G4S W;  1VQ4 W;  1VQQ A;  1K8A X;  1Q86 X;  5JVG W;  5GAH a;  3CXC V;  3CMA W;  3CCL W;  3CME W;  2OTL W;  1VQ7 W;  1VQ9 W;  1R6O C;  1MBX C;  3DLL W;  1N8R X;  2OTJ W;  3I55 W;  4U67 W;  5DM7 W;  3G6E W;  1MBU C;  1VQP W;  5CA3 A;  1QVG V;  4WFB W;  2W9R A;  1KD1 X;  1KQS V;  3G71 W;  3G3P A;  1YIJ W;  5GAG a;  4BL2 A;  4WCE W;  3W7X A;  1MBV B;  1VQ6 W;  2WA8 A;  1K73 X;  1MG9 A;  4YJX A;  4C1N A;  2ZJP W;  1DD4 A;  1M90 X;  1Q7Y X;  1VQK W;  1VQL W; 
#chains in the Genus database with same CATH homology
 3PIO W;  1YJW W;  3CF5 W;  3CCE W;  1BXY A;  1YJN W;  3CC4 W;  1K9M X;  1Q81 X;  3CCR W;  1JJ2 V;  3CCV W;  1M1K X;  1VQM W;  4IO9 W;  4IOC W;  1VQO W;  1YHQ W;  5GAD a;  1S72 W;  4WF9 W;  1KC8 X;  1VQ5 W;  5GAE a;  1YI2 W;  2ZJQ W;  3CCQ W;  2QA4 W;  3CCU W;  3CCJ W;  4WFA W;  1Q82 X;  3CC2 W;  3CCM W;  3I56 W;  3OW2 V;  3CCS W;  4WFN W;  3CD6 W;  5HL7 W;  1YIT W;  3CC7 W;  2ZJR W;  4IOA W;  1NJI X;  1VQN W;  3PIP W;  5DM6 W;  2QEX W;  1QVF V;  3J7Z Z;  1W2B V;  4UY8 Z;  1VQ8 W;  5JVH W;  1YJ9 W;  3CPW V;  3G4S W;  1VQ4 W;  1K8A X;  1Q86 X;  5JVG W;  5GAH a;  3CXC V;  3CMA W;  3CCL W;  3CME W;  2OTL W;  1VQ7 W;  1VQ9 W;  3DLL W;  1N8R X;  2OTJ W;  3I55 W;  4U67 W;  5DM7 W;  3G6E W;  1VQP W;  1QVG V;  4WFB W;  1KD1 X;  1KQS V;  3G71 W;  1YIJ W;  5GAG a;  4WCE W;  1VQ6 W;  1K73 X;  4C1N A;  2ZJP W;  1M90 X;  1Q7Y X;  1VQK W;  1VQL W; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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