3CCJW

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation c2534u
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 43
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3ccjW02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 3ccjW01
3G6EW 1K8AX 1N8RX 4IOAW 1YJWW 1VQ4W 2ZJPW 5DM6W 3PIPW 1Q86X 4IO9W 5GAEa 1QVFV 1YITW 3DLLW 3I55W 3G71W 3CCEW 3CXCV 5HL7W 1K73X 1VQPW 1VQMW 3CCJW 3CF5W 3PIOW 4U67W 3CCQW 2OTLW 1VQLW 2QA4W 1M1KX 3CC4W 1VQ9W 2OTJW 1Q7YX 5GADa 1KQSV 3CMAW 1VQ6W 4WFAW 1VQKW 1K9MX 5DM7W 5JVHW 1S72W 1YJ9W 3J7ZZ 3CCUW 3CMEW 1KD1X 3CD6W 1NJIX 4WFNW 1QVGV 1KC8X 1W2BV 1JJ2V 1M90X 1BXYA 3G4SW 2ZJQW 3CCSW 2QEXW 3CC7W 1VQ5W 1VQNW 3CCVW 1YI2W 1YJNW 1VQ8W 5JVGW 5GAGa 3CCMW 3OW2V 4IOCW 1Q81X 4WCEW 3CC2W 1VQ7W 1YHQW 3I56W 4UY8Z 3CPWV 1VQOW 1Q82X 4WF9W 4WFBW 2ZJRW 1YIJW 3CCLW 3CCRW 5GAHa
chains in the Genus database with same CATH superfamily
4YJXA 3GQ1A 3G6EW 1K8AX 4YJMA 3G3PA 1N8RX 4IOAW 3ZG5A 4CJNA 1YJWW 1VQ4W 3O1FA 4C1NA 1MG9A 2ZJPW 1MWRA 5DM6W 3O2OA 1MBUC 3GQ0A 1Q86X 3PIPW 4IO9W 5GAEa 1QVFV 1DD3A 1YITW 3DLLW 3I55W 1CTFA 3G71W 3CCEW 3CXCV 5HL7W 1K73X 1VQPW 1VQMW 3CCJW 3ZG0A 3CF5W 4YKAA 3PIOW 1MBXC 3W7WA 4U67W 2WA9A 3CCQW 2OTLW 1VQLW 2QA4W 1M1KX 3CC4W 1RQSA 1VQ9W 2OTJW 2W9RA 1Q7YX 3O1FB 5GADa 3W7XA 4BL3A 1KQSV 3CMAW 1VQ6W 1VQKW 4WFAW 5M18A 1K9MX 5DM7W 5JVHW 2WA8A 1R6QC 1S72W 1YJ9W 3J7ZZ 1MWUA 3CCUW 3W7SA 5GW7A 4DKIA 3CMEW 1KD1X 3CD6W 1DD4A 1NJIX 4WFNW 1LZWA 1QVGV 1RQVA 1KC8X 1W2BV 1JJ2V 1M90X 4BL2A 3G19A 3W7TA 1BXYA 3G4SW 2ZJQW 3CCSW 2QEXW 3CC7W 1VQ5W 1VQNW 3CCVW 1YI2W 1YJNW 1R6OC 1MWTA 1VQ8W 5JVGW 5CA3A 1MBVB 5GAGa 3CCMW 3OW2V 3D3IA 4IOCW 1Q81X 4WCEW 3CC2W 1VQ7W 4CPKA 1YHQW 5M1AA 3W7UA 3I56W 4UY8Z 3GW1A 3O2BA 1RQUA 3CPWV 1VQOW 1Q82X 3O2HA 4WF9W 4WFBW 2ZJRW 1MWSA 3ZFZA 1YIJW 5M19A 3DNJA 3CCLW 1VQQA 3CCRW 5GAHa 3G1BA
chains in the Genus database with same CATH topology
3G6EW 1K8AX 1N8RX 4IOAW 1YJWW 1VQ4W 4C1NA 2ZJPW 5DM6W 3PIPW 1Q86X 4IO9W 5GAEa 1QVFV 1YITW 3DLLW 3I55W 3G71W 3CCEW 3CXCV 5HL7W 1K73X 1VQPW 1VQMW 3CCJW 3CF5W 3PIOW 4U67W 3CCQW 2OTLW 1VQLW 2QA4W 1M1KX 3CC4W 1VQ9W 2OTJW 1Q7YX 5GADa 1KQSV 3CMAW 1VQ6W 4WFAW 1VQKW 1K9MX 5DM7W 5JVHW 1S72W 1YJ9W 3J7ZZ 3CCUW 3CMEW 1KD1X 3CD6W 1NJIX 4WFNW 1QVGV 1KC8X 1W2BV 1JJ2V 1M90X 1BXYA 3G4SW 2ZJQW 3CCSW 2QEXW 3CC7W 1VQ5W 1VQNW 3CCVW 1YI2W 1YJNW 1VQ8W 5JVGW 5GAGa 3CCMW 3OW2V 4IOCW 1Q81X 4WCEW 3CC2W 1VQ7W 1YHQW 3I56W 4UY8Z 3CPWV 1VQOW 1Q82X 4WF9W 4WFBW 2ZJRW 1YIJW 3CCLW 3CCRW 5GAHa
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G6E W;  1K8A X;  1N8R X;  4IOA W;  1YJW W;  1VQ4 W;  2ZJP W;  5DM6 W;  3PIP W;  1Q86 X;  4IO9 W;  5GAE a;  1QVF V;  1YIT W;  3DLL W;  3I55 W;  3G71 W;  3CCE W;  3CXC V;  5HL7 W;  1K73 X;  1VQP W;  1VQM W;  3CCJ W;  3CF5 W;  3PIO W;  4U67 W;  3CCQ W;  2OTL W;  1VQL W;  2QA4 W;  1M1K X;  3CC4 W;  1VQ9 W;  2OTJ W;  1Q7Y X;  5GAD a;  1KQS V;  3CMA W;  1VQ6 W;  4WFA W;  1VQK W;  1K9M X;  5DM7 W;  5JVH W;  1S72 W;  1YJ9 W;  3J7Z Z;  3CCU W;  3CME W;  1KD1 X;  3CD6 W;  1NJI X;  4WFN W;  1QVG V;  1KC8 X;  1W2B V;  1JJ2 V;  1M90 X;  1BXY A;  3G4S W;  2ZJQ W;  3CCS W;  2QEX W;  3CC7 W;  1VQ5 W;  1VQN W;  3CCV W;  1YI2 W;  1YJN W;  1VQ8 W;  5JVG W;  5GAG a;  3CCM W;  3OW2 V;  4IOC W;  1Q81 X;  4WCE W;  3CC2 W;  1VQ7 W;  1YHQ W;  3I56 W;  4UY8 Z;  3CPW V;  1VQO W;  1Q82 X;  4WF9 W;  4WFB W;  2ZJR W;  1YIJ W;  3CCL W;  3CCR W;  5GAH a; 
#chains in the Genus database with same CATH topology
 4YJX A;  3GQ1 A;  3G6E W;  1K8A X;  4YJM A;  3G3P A;  1N8R X;  4IOA W;  3ZG5 A;  4CJN A;  1YJW W;  1VQ4 W;  3O1F A;  4C1N A;  1MG9 A;  2ZJP W;  1MWR A;  5DM6 W;  3O2O A;  1MBU C;  3GQ0 A;  1Q86 X;  3PIP W;  4IO9 W;  5GAE a;  1QVF V;  1DD3 A;  1YIT W;  3DLL W;  3I55 W;  1CTF A;  3G71 W;  3CCE W;  3CXC V;  5HL7 W;  1K73 X;  1VQP W;  1VQM W;  3CCJ W;  3ZG0 A;  3CF5 W;  4YKA A;  3PIO W;  1MBX C;  3W7W A;  4U67 W;  2WA9 A;  3CCQ W;  2OTL W;  1VQL W;  2QA4 W;  1M1K X;  3CC4 W;  1RQS A;  1VQ9 W;  2OTJ W;  2W9R A;  1Q7Y X;  3O1F B;  5GAD a;  3W7X A;  4BL3 A;  1KQS V;  3CMA W;  1VQ6 W;  1VQK W;  4WFA W;  5M18 A;  1K9M X;  5DM7 W;  5JVH W;  2WA8 A;  1R6Q C;  1S72 W;  1YJ9 W;  3J7Z Z;  1MWU A;  3CCU W;  3W7S A;  5GW7 A;  4DKI A;  3CME W;  1KD1 X;  3CD6 W;  1DD4 A;  1NJI X;  4WFN W;  1LZW A;  1QVG V;  1RQV A;  1KC8 X;  1W2B V;  1JJ2 V;  1M90 X;  4BL2 A;  3G19 A;  3W7T A;  1BXY A;  3G4S W;  2ZJQ W;  3CCS W;  2QEX W;  3CC7 W;  1VQ5 W;  1VQN W;  3CCV W;  1YI2 W;  1YJN W;  1R6O C;  1MWT A;  1VQ8 W;  5JVG W;  5CA3 A;  1MBV B;  5GAG a;  3CCM W;  3OW2 V;  3D3I A;  4IOC W;  1Q81 X;  4WCE W;  3CC2 W;  1VQ7 W;  4CPK A;  1YHQ W;  5M1A A;  3W7U A;  3I56 W;  4UY8 Z;  3GW1 A;  3O2B A;  1RQU A;  3CPW V;  1VQO W;  1Q82 X;  3O2H A;  4WF9 W;  4WFB W;  2ZJR W;  1MWS A;  3ZFZ A;  1YIJ W;  5M19 A;  3DNJ A;  3CCL W;  1VQQ A;  3CCR W;  5GAH a;  3G1B A; 
#chains in the Genus database with same CATH homology
 3G6E W;  1K8A X;  1N8R X;  4IOA W;  1YJW W;  1VQ4 W;  4C1N A;  2ZJP W;  5DM6 W;  3PIP W;  1Q86 X;  4IO9 W;  5GAE a;  1QVF V;  1YIT W;  3DLL W;  3I55 W;  3G71 W;  3CCE W;  3CXC V;  5HL7 W;  1K73 X;  1VQP W;  1VQM W;  3CCJ W;  3CF5 W;  3PIO W;  4U67 W;  3CCQ W;  2OTL W;  1VQL W;  2QA4 W;  1M1K X;  3CC4 W;  1VQ9 W;  2OTJ W;  1Q7Y X;  5GAD a;  1KQS V;  3CMA W;  1VQ6 W;  4WFA W;  1VQK W;  1K9M X;  5DM7 W;  5JVH W;  1S72 W;  1YJ9 W;  3J7Z Z;  3CCU W;  3CME W;  1KD1 X;  3CD6 W;  1NJI X;  4WFN W;  1QVG V;  1KC8 X;  1W2B V;  1JJ2 V;  1M90 X;  1BXY A;  3G4S W;  2ZJQ W;  3CCS W;  2QEX W;  3CC7 W;  1VQ5 W;  1VQN W;  3CCV W;  1YI2 W;  1YJN W;  1VQ8 W;  5JVG W;  5GAG a;  3CCM W;  3OW2 V;  4IOC W;  1Q81 X;  4WCE W;  3CC2 W;  1VQ7 W;  1YHQ W;  3I56 W;  4UY8 Z;  3CPW V;  1VQO W;  1Q82 X;  4WF9 W;  4WFB W;  2ZJR W;  1YIJ W;  3CCL W;  3CCR W;  5GAH a; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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