3CCLW

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535c. density for anisomycin is visible but not included in model.
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 49
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3cclW02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 3cclW01
1N8RX 1YITW 4IO9W 1W2BV 3CCEW 3CCSW 1M1KX 2ZJQW 4U67W 3CCJW 3CC7W 3I55W 4IOAW 2ZJPW 3CC4W 4UY8Z 3G71W 1Q82X 1VQOW 3DLLW 3J7ZZ 1YHQW 4WFNW 1KD1X 1YJNW 1YI2W 1BXYA 1VQ4W 1VQ6W 1VQNW 5GADa 3CCQW 1S72W 2OTJW 1Q81X 1NJIX 4WCEW 2ZJRW 1Q86X 1QVGV 3CCMW 3CC2W 1Q7YX 1VQKW 5JVGW 1M90X 3G6EW 3PIOW 1QVFV 1VQ9W 1YJWW 3OW2V 5GAGa 1YIJW 3G4SW 1K9MX 3PIPW 1VQ8W 3CMAW 1KC8X 2OTLW 4WFAW 2QEXW 1VQLW 3CF5W 1VQ5W 3CMEW 5DM6W 4IOCW 2QA4W 3I56W 4WF9W 1VQPW 5HL7W 3CPWV 3CCUW 3CCLW 1JJ2V 1K73X 5JVHW 5GAHa 5DM7W 1KQSV 4WFBW 1VQ7W 1YJ9W 5GAEa 1K8AX 3CD6W 1VQMW 3CCRW 3CXCV 3CCVW
chains in the Genus database with same CATH superfamily
1N8RX 1YITW 4IO9W 1W2BV 3CCEW 3CCSW 1M1KX 1MWTA 4CJNA 4BL3A 2ZJQW 4U67W 3CCJW 3CC7W 3I55W 3W7WA 4IOAW 2ZJPW 3CC4W 3O2OA 5M19A 4YKAA 4UY8Z 3G71W 3O1FA 1DD4A 1Q82X 1VQOW 3DLLW 1VQQA 1R6QC 3J7ZZ 1YHQW 4WFNW 3W7XA 1KD1X 1YJNW 1YI2W 3O1FB 3ZG5A 1BXYA 1VQ4W 1VQ6W 1R6OC 1VQNW 5GADa 3CCQW 1S72W 5M18A 3W7UA 2OTJW 1Q81X 1NJIX 1MWSA 1RQVA 5M1AA 4WCEW 2ZJRW 4YJMA 1Q86X 1RQSA 1QVGV 3CCMW 3CC2W 3GQ0A 2W9RA 1Q7YX 3O2BA 5CA3A 2WA9A 1VQKW 5JVGW 1M90X 3G6EW 1RQUA 1MBXC 1MG9A 1MWRA 3D3IA 4YJXA 3PIOW 1MBUC 1QVFV 1DD3A 3G1BA 1VQ9W 1YJWW 4BL2A 4DKIA 3OW2V 5GAGa 1YIJW 3G4SW 3GW1A 1K9MX 3PIPW 1VQ8W 3CMAW 1KC8X 2OTLW 1MBVB 3DNJA 4WFAW 3W7TA 3ZFZA 2QEXW 1VQLW 3CF5W 1VQ5W 3CMEW 5DM6W 4IOCW 2QA4W 3I56W 4WF9W 1VQPW 5HL7W 3CPWV 3W7SA 3CCUW 3CCLW 1JJ2V 3ZG0A 3GQ1A 4CPKA 1K73X 5JVHW 5GAHa 1MWUA 1CTFA 5DM7W 5GW7A 1KQSV 4WFBW 1VQ7W 2WA8A 1LZWA 1YJ9W 3O2HA 5GAEa 1K8AX 4C1NA 3CD6W 3G3PA 1VQMW 3G19A 3CCRW 3CXCV 3CCVW
chains in the Genus database with same CATH topology
1N8RX 1YITW 4IO9W 1W2BV 3CCEW 3CCSW 1M1KX 2ZJQW 4U67W 3CCJW 3CC7W 3I55W 4IOAW 2ZJPW 3CC4W 4UY8Z 3G71W 1Q82X 1VQOW 3DLLW 3J7ZZ 1YHQW 4WFNW 1KD1X 1YJNW 1YI2W 1BXYA 1VQ4W 1VQ6W 1VQNW 5GADa 3CCQW 1S72W 2OTJW 1Q81X 1NJIX 4WCEW 2ZJRW 1Q86X 1QVGV 3CCMW 3CC2W 1Q7YX 1VQKW 5JVGW 1M90X 3G6EW 3PIOW 1QVFV 1VQ9W 1YJWW 3OW2V 5GAGa 1YIJW 3G4SW 1K9MX 3PIPW 1VQ8W 3CMAW 1KC8X 2OTLW 4WFAW 2QEXW 1VQLW 3CF5W 1VQ5W 3CMEW 5DM6W 4IOCW 2QA4W 3I56W 4WF9W 1VQPW 5HL7W 3CPWV 3CCUW 3CCLW 1JJ2V 1K73X 5JVHW 5GAHa 5DM7W 1KQSV 4WFBW 1VQ7W 1YJ9W 5GAEa 1K8AX 4C1NA 3CD6W 1VQMW 3CCRW 3CXCV 3CCVW
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1N8R X;  1YIT W;  4IO9 W;  1W2B V;  3CCE W;  3CCS W;  1M1K X;  2ZJQ W;  4U67 W;  3CCJ W;  3CC7 W;  3I55 W;  4IOA W;  2ZJP W;  3CC4 W;  4UY8 Z;  3G71 W;  1Q82 X;  1VQO W;  3DLL W;  3J7Z Z;  1YHQ W;  4WFN W;  1KD1 X;  1YJN W;  1YI2 W;  1BXY A;  1VQ4 W;  1VQ6 W;  1VQN W;  5GAD a;  3CCQ W;  1S72 W;  2OTJ W;  1Q81 X;  1NJI X;  4WCE W;  2ZJR W;  1Q86 X;  1QVG V;  3CCM W;  3CC2 W;  1Q7Y X;  1VQK W;  5JVG W;  1M90 X;  3G6E W;  3PIO W;  1QVF V;  1VQ9 W;  1YJW W;  3OW2 V;  5GAG a;  1YIJ W;  3G4S W;  1K9M X;  3PIP W;  1VQ8 W;  3CMA W;  1KC8 X;  2OTL W;  4WFA W;  2QEX W;  1VQL W;  3CF5 W;  1VQ5 W;  3CME W;  5DM6 W;  4IOC W;  2QA4 W;  3I56 W;  4WF9 W;  1VQP W;  5HL7 W;  3CPW V;  3CCU W;  3CCL W;  1JJ2 V;  1K73 X;  5JVH W;  5GAH a;  5DM7 W;  1KQS V;  4WFB W;  1VQ7 W;  1YJ9 W;  5GAE a;  1K8A X;  3CD6 W;  1VQM W;  3CCR W;  3CXC V;  3CCV W; 
#chains in the Genus database with same CATH topology
 1N8R X;  1YIT W;  4IO9 W;  1W2B V;  3CCE W;  3CCS W;  1M1K X;  1MWT A;  4CJN A;  4BL3 A;  2ZJQ W;  4U67 W;  3CCJ W;  3CC7 W;  3I55 W;  3W7W A;  4IOA W;  2ZJP W;  3CC4 W;  3O2O A;  5M19 A;  4YKA A;  4UY8 Z;  3G71 W;  3O1F A;  1DD4 A;  1Q82 X;  1VQO W;  3DLL W;  1VQQ A;  1R6Q C;  3J7Z Z;  1YHQ W;  4WFN W;  3W7X A;  1KD1 X;  1YJN W;  1YI2 W;  3O1F B;  3ZG5 A;  1BXY A;  1VQ4 W;  1VQ6 W;  1R6O C;  1VQN W;  5GAD a;  3CCQ W;  1S72 W;  5M18 A;  3W7U A;  2OTJ W;  1Q81 X;  1NJI X;  1MWS A;  1RQV A;  5M1A A;  4WCE W;  2ZJR W;  4YJM A;  1Q86 X;  1RQS A;  1QVG V;  3CCM W;  3CC2 W;  3GQ0 A;  2W9R A;  1Q7Y X;  3O2B A;  5CA3 A;  2WA9 A;  1VQK W;  5JVG W;  1M90 X;  3G6E W;  1RQU A;  1MBX C;  1MG9 A;  1MWR A;  3D3I A;  4YJX A;  3PIO W;  1MBU C;  1QVF V;  1DD3 A;  3G1B A;  1VQ9 W;  1YJW W;  4BL2 A;  4DKI A;  3OW2 V;  5GAG a;  1YIJ W;  3G4S W;  3GW1 A;  1K9M X;  3PIP W;  1VQ8 W;  3CMA W;  1KC8 X;  2OTL W;  1MBV B;  3DNJ A;  4WFA W;  3W7T A;  3ZFZ A;  2QEX W;  1VQL W;  3CF5 W;  1VQ5 W;  3CME W;  5DM6 W;  4IOC W;  2QA4 W;  3I56 W;  4WF9 W;  1VQP W;  5HL7 W;  3CPW V;  3W7S A;  3CCU W;  3CCL W;  1JJ2 V;  3ZG0 A;  3GQ1 A;  4CPK A;  1K73 X;  5JVH W;  5GAH a;  1MWU A;  1CTF A;  5DM7 W;  5GW7 A;  1KQS V;  4WFB W;  1VQ7 W;  2WA8 A;  1LZW A;  1YJ9 W;  3O2H A;  5GAE a;  1K8A X;  4C1N A;  3CD6 W;  3G3P A;  1VQM W;  3G19 A;  3CCR W;  3CXC V;  3CCV W; 
#chains in the Genus database with same CATH homology
 1N8R X;  1YIT W;  4IO9 W;  1W2B V;  3CCE W;  3CCS W;  1M1K X;  2ZJQ W;  4U67 W;  3CCJ W;  3CC7 W;  3I55 W;  4IOA W;  2ZJP W;  3CC4 W;  4UY8 Z;  3G71 W;  1Q82 X;  1VQO W;  3DLL W;  3J7Z Z;  1YHQ W;  4WFN W;  1KD1 X;  1YJN W;  1YI2 W;  1BXY A;  1VQ4 W;  1VQ6 W;  1VQN W;  5GAD a;  3CCQ W;  1S72 W;  2OTJ W;  1Q81 X;  1NJI X;  4WCE W;  2ZJR W;  1Q86 X;  1QVG V;  3CCM W;  3CC2 W;  1Q7Y X;  1VQK W;  5JVG W;  1M90 X;  3G6E W;  3PIO W;  1QVF V;  1VQ9 W;  1YJW W;  3OW2 V;  5GAG a;  1YIJ W;  3G4S W;  1K9M X;  3PIP W;  1VQ8 W;  3CMA W;  1KC8 X;  2OTL W;  4WFA W;  2QEX W;  1VQL W;  3CF5 W;  1VQ5 W;  3CME W;  5DM6 W;  4IOC W;  2QA4 W;  3I56 W;  4WF9 W;  1VQP W;  5HL7 W;  3CPW V;  3CCU W;  3CCL W;  1JJ2 V;  1K73 X;  5JVH W;  5GAH a;  5DM7 W;  1KQS V;  4WFB W;  1VQ7 W;  1YJ9 W;  5GAE a;  1K8A X;  4C1N A;  3CD6 W;  1VQM W;  3CCR W;  3CXC V;  3CCV W; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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