3CCQW

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488u
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 50
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3ccqW02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 3ccqW01
1YI2W 1Q82X 3OW2V 1S72W 1Q7YX 3PIPW 3J7ZZ 5GAEa 2QA4W 2OTLW 1VQ8W 5GADa 3CMAW 5JVGW 3CCQW 1KD1X 1N8RX 1VQLW 3G6EW 3CXCV 1K9MX 1VQNW 5DM7W 3CD6W 2QEXW 3I56W 3PIOW 3CCRW 4WF9W 4WFAW 3CC4W 2ZJRW 1BXYA 5DM6W 1VQ6W 1VQ4W 1M90X 1JJ2V 3CCLW 5GAGa 1VQ7W 3CCJW 3CMEW 1VQPW 3CPWV 2OTJW 3CCSW 1VQ9W 1M1KX 3G71W 1YITW 1KQSV 1Q81X 1KC8X 1VQKW 1QVGV 3CF5W 1YJWW 1YHQW 1VQOW 1YJ9W 5GAHa 4U67W 1W2BV 1K73X 3I55W 5HL7W 3CCMW 1YIJW 4IOCW 4WFNW 4WFBW 3CCVW 1VQ5W 1Q86X 3DLLW 2ZJPW 3CCEW 4UY8Z 3G4SW 3CCUW 3CC2W 1QVFV 5JVHW 4IOAW 1NJIX 4IO9W 1VQMW 1K8AX 3CC7W 2ZJQW 1YJNW 4WCEW
chains in the Genus database with same CATH superfamily
1R6OC 4C1NA 3GW1A 4BL2A 1RQVA 1YI2W 1Q82X 1MWUA 3OW2V 1MG9A 3W7TA 5GW7A 4YJXA 2W9RA 1VQQA 1S72W 1Q7YX 3PIPW 3J7ZZ 5GAEa 2QA4W 2OTLW 1MWTA 5CA3A 1VQ8W 5GADa 3CMAW 5JVGW 3CCQW 3G1BA 3W7XA 1KD1X 1N8RX 1DD3A 1MBVB 1VQLW 4BL3A 3G6EW 3CXCV 1K9MX 1VQNW 5DM7W 3CD6W 2QEXW 3I56W 3PIOW 3CCRW 3W7WA 4WF9W 4WFAW 3GQ1A 3O2HA 3CC4W 2ZJRW 1LZWA 1BXYA 5DM6W 1VQ6W 1VQ4W 1M90X 1RQUA 1JJ2V 3CCLW 5GAGa 5M19A 1VQ7W 3CCJW 3CMEW 1VQPW 2WA9A 3CPWV 2OTJW 3ZG0A 3CCSW 1VQ9W 1M1KX 3D3IA 3W7UA 3G71W 1YITW 1KQSV 1Q81X 1KC8X 3ZG5A 1VQKW 1QVGV 1MBUC 3CF5W 1DD4A 1YJWW 3ZFZA 1YHQW 1VQOW 1YJ9W 4CPKA 5GAHa 4U67W 5M1AA 3G3PA 1W2BV 1K73X 3I55W 1MBXC 3DNJA 5HL7W 4CJNA 4YKAA 5M18A 3GQ0A 3O1FB 3CCMW 1YIJW 3G19A 4IOCW 4DKIA 4WFNW 4WFBW 3CCVW 1VQ5W 3O1FA 3W7SA 1Q86X 3O2BA 1MWRA 3DLLW 1CTFA 2ZJPW 3CCEW 4UY8Z 3G4SW 3CCUW 3CC2W 4YJMA 1QVFV 1R6QC 2WA8A 5JVHW 4IOAW 1NJIX 4IO9W 1VQMW 1K8AX 3CC7W 3O2OA 2ZJQW 1YJNW 1MWSA 1RQSA 4WCEW
chains in the Genus database with same CATH topology
4C1NA 1YI2W 1Q82X 3OW2V 1S72W 1Q7YX 3PIPW 3J7ZZ 5GAEa 2QA4W 2OTLW 1VQ8W 5GADa 3CMAW 5JVGW 3CCQW 1KD1X 1N8RX 1VQLW 3G6EW 3CXCV 1K9MX 1VQNW 5DM7W 3CD6W 2QEXW 3I56W 3PIOW 3CCRW 4WF9W 4WFAW 3CC4W 2ZJRW 1BXYA 5DM6W 1VQ6W 1VQ4W 1M90X 1JJ2V 3CCLW 5GAGa 1VQ7W 3CCJW 3CMEW 1VQPW 3CPWV 2OTJW 3CCSW 1VQ9W 1M1KX 3G71W 1YITW 1KQSV 1Q81X 1KC8X 1VQKW 1QVGV 3CF5W 1YJWW 1YHQW 1VQOW 1YJ9W 5GAHa 4U67W 1W2BV 1K73X 3I55W 5HL7W 3CCMW 1YIJW 4IOCW 4WFNW 4WFBW 3CCVW 1VQ5W 1Q86X 3DLLW 2ZJPW 3CCEW 4UY8Z 3G4SW 3CCUW 3CC2W 1QVFV 5JVHW 4IOAW 1NJIX 4IO9W 1VQMW 1K8AX 3CC7W 2ZJQW 1YJNW 4WCEW
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YI2 W;  1Q82 X;  3OW2 V;  1S72 W;  1Q7Y X;  3PIP W;  3J7Z Z;  5GAE a;  2QA4 W;  2OTL W;  1VQ8 W;  5GAD a;  3CMA W;  5JVG W;  3CCQ W;  1KD1 X;  1N8R X;  1VQL W;  3G6E W;  3CXC V;  1K9M X;  1VQN W;  5DM7 W;  3CD6 W;  2QEX W;  3I56 W;  3PIO W;  3CCR W;  4WF9 W;  4WFA W;  3CC4 W;  2ZJR W;  1BXY A;  5DM6 W;  1VQ6 W;  1VQ4 W;  1M90 X;  1JJ2 V;  3CCL W;  5GAG a;  1VQ7 W;  3CCJ W;  3CME W;  1VQP W;  3CPW V;  2OTJ W;  3CCS W;  1VQ9 W;  1M1K X;  3G71 W;  1YIT W;  1KQS V;  1Q81 X;  1KC8 X;  1VQK W;  1QVG V;  3CF5 W;  1YJW W;  1YHQ W;  1VQO W;  1YJ9 W;  5GAH a;  4U67 W;  1W2B V;  1K73 X;  3I55 W;  5HL7 W;  3CCM W;  1YIJ W;  4IOC W;  4WFN W;  4WFB W;  3CCV W;  1VQ5 W;  1Q86 X;  3DLL W;  2ZJP W;  3CCE W;  4UY8 Z;  3G4S W;  3CCU W;  3CC2 W;  1QVF V;  5JVH W;  4IOA W;  1NJI X;  4IO9 W;  1VQM W;  1K8A X;  3CC7 W;  2ZJQ W;  1YJN W;  4WCE W; 
#chains in the Genus database with same CATH topology
 1R6O C;  4C1N A;  3GW1 A;  4BL2 A;  1RQV A;  1YI2 W;  1Q82 X;  1MWU A;  3OW2 V;  1MG9 A;  3W7T A;  5GW7 A;  4YJX A;  2W9R A;  1VQQ A;  1S72 W;  1Q7Y X;  3PIP W;  3J7Z Z;  5GAE a;  2QA4 W;  2OTL W;  1MWT A;  5CA3 A;  1VQ8 W;  5GAD a;  3CMA W;  5JVG W;  3CCQ W;  3G1B A;  3W7X A;  1KD1 X;  1N8R X;  1DD3 A;  1MBV B;  1VQL W;  4BL3 A;  3G6E W;  3CXC V;  1K9M X;  1VQN W;  5DM7 W;  3CD6 W;  2QEX W;  3I56 W;  3PIO W;  3CCR W;  3W7W A;  4WF9 W;  4WFA W;  3GQ1 A;  3O2H A;  3CC4 W;  2ZJR W;  1LZW A;  1BXY A;  5DM6 W;  1VQ6 W;  1VQ4 W;  1M90 X;  1RQU A;  1JJ2 V;  3CCL W;  5GAG a;  5M19 A;  1VQ7 W;  3CCJ W;  3CME W;  1VQP W;  2WA9 A;  3CPW V;  2OTJ W;  3ZG0 A;  3CCS W;  1VQ9 W;  1M1K X;  3D3I A;  3W7U A;  3G71 W;  1YIT W;  1KQS V;  1Q81 X;  1KC8 X;  3ZG5 A;  1VQK W;  1QVG V;  1MBU C;  3CF5 W;  1DD4 A;  1YJW W;  3ZFZ A;  1YHQ W;  1VQO W;  1YJ9 W;  4CPK A;  5GAH a;  4U67 W;  5M1A A;  3G3P A;  1W2B V;  1K73 X;  3I55 W;  1MBX C;  3DNJ A;  5HL7 W;  4CJN A;  4YKA A;  5M18 A;  3GQ0 A;  3O1F B;  3CCM W;  1YIJ W;  3G19 A;  4IOC W;  4DKI A;  4WFN W;  4WFB W;  3CCV W;  1VQ5 W;  3O1F A;  3W7S A;  1Q86 X;  3O2B A;  1MWR A;  3DLL W;  1CTF A;  2ZJP W;  3CCE W;  4UY8 Z;  3G4S W;  3CCU W;  3CC2 W;  4YJM A;  1QVF V;  1R6Q C;  2WA8 A;  5JVH W;  4IOA W;  1NJI X;  4IO9 W;  1VQM W;  1K8A X;  3CC7 W;  3O2O A;  2ZJQ W;  1YJN W;  1MWS A;  1RQS A;  4WCE W; 
#chains in the Genus database with same CATH homology
 4C1N A;  1YI2 W;  1Q82 X;  3OW2 V;  1S72 W;  1Q7Y X;  3PIP W;  3J7Z Z;  5GAE a;  2QA4 W;  2OTL W;  1VQ8 W;  5GAD a;  3CMA W;  5JVG W;  3CCQ W;  1KD1 X;  1N8R X;  1VQL W;  3G6E W;  3CXC V;  1K9M X;  1VQN W;  5DM7 W;  3CD6 W;  2QEX W;  3I56 W;  3PIO W;  3CCR W;  4WF9 W;  4WFA W;  3CC4 W;  2ZJR W;  1BXY A;  5DM6 W;  1VQ6 W;  1VQ4 W;  1M90 X;  1JJ2 V;  3CCL W;  5GAG a;  1VQ7 W;  3CCJ W;  3CME W;  1VQP W;  3CPW V;  2OTJ W;  3CCS W;  1VQ9 W;  1M1K X;  3G71 W;  1YIT W;  1KQS V;  1Q81 X;  1KC8 X;  1VQK W;  1QVG V;  3CF5 W;  1YJW W;  1YHQ W;  1VQO W;  1YJ9 W;  5GAH a;  4U67 W;  1W2B V;  1K73 X;  3I55 W;  5HL7 W;  3CCM W;  1YIJ W;  4IOC W;  4WFN W;  4WFB W;  3CCV W;  1VQ5 W;  1Q86 X;  3DLL W;  2ZJP W;  3CCE W;  4UY8 Z;  3G4S W;  3CCU W;  3CC2 W;  1QVF V;  5JVH W;  4IOA W;  1NJI X;  4IO9 W;  1VQM W;  1K8A X;  3CC7 W;  2ZJQ W;  1YJN W;  4WCE W; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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