3CCRW

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488c. density for anisomycin is visible but not included in the model.
Total Genus 47
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 47
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3ccrW02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 3ccrW01
1KD1X 4WFAW 3CCQW 1YHQW 5GAEa 5DM7W 1S72W 1VQMW 3CCLW 1VQ4W 1VQ8W 3CPWV 1M90X 2OTJW 4IOAW 1VQOW 3CCMW 1W2BV 1YI2W 3CCSW 1Q7YX 1YIJW 1K9MX 2OTLW 4U67W 4IOCW 1JJ2V 3CC4W 4UY8Z 4WF9W 5DM6W 3CMAW 1YJNW 1VQ6W 5HL7W 2ZJRW 2QA4W 1VQNW 3I56W 1KQSV 1VQ5W 2QEXW 4WFBW 1VQ9W 3CC7W 3CD6W 5GAHa 3PIOW 1BXYA 3CCVW 3G6EW 1YJ9W 3CC2W 3CCRW 1QVFV 3G71W 1YJWW 3I55W 1KC8X 1VQLW 5JVHW 1Q86X 3G4SW 3J7ZZ 1Q82X 1M1KX 3CF5W 3CCUW 2ZJPW 5GADa 4IO9W 3CMEW 3CCJW 1K73X 4WCEW 4WFNW 3DLLW 1VQPW 1QVGV 5JVGW 5GAGa 3CXCV 3PIPW 1NJIX 1YITW 3OW2V 1VQ7W 1N8RX 1Q81X 1K8AX 1VQKW 2ZJQW 3CCEW
chains in the Genus database with same CATH superfamily
5M1AA 3GW1A 3O2BA 3W7WA 1KD1X 4WFAW 3CCQW 5M19A 1YHQW 5GAEa 5DM7W 3W7UA 5M18A 1S72W 1VQMW 3CCLW 1VQ4W 1VQ8W 3CPWV 1M90X 2OTJW 4IOAW 1VQOW 3CCMW 1W2BV 1RQVA 3G1BA 1DD3A 1YI2W 3CCSW 1Q7YX 3W7XA 2W9RA 1YIJW 1R6QC 2WA9A 4BL2A 1K9MX 2OTLW 4U67W 4IOCW 1JJ2V 3CC4W 4UY8Z 4WF9W 5DM6W 3CMAW 1YJNW 3O2HA 4BL3A 1MWTA 1CTFA 2WA8A 1VQ6W 5HL7W 3ZFZA 2QA4W 1VQNW 3GQ1A 2ZJRW 3I56W 5GW7A 1KQSV 3GQ0A 1LZWA 4CJNA 1VQ5W 2QEXW 4WFBW 1VQ9W 3CC7W 3CD6W 5GAHa 1MG9A 3PIOW 1BXYA 3O2OA 3CCVW 3G6EW 1YJ9W 1MBXC 3CCRW 3CC2W 1QVFV 3O1FA 4YJMA 3G71W 1YJWW 1MBVB 1MWUA 1MBUC 4CPKA 1DD4A 3I55W 1KC8X 1VQLW 5JVHW 1Q86X 4DKIA 3G4SW 1RQUA 3W7SA 3J7ZZ 1Q82X 1M1KX 3CF5W 3CCUW 4C1NA 2ZJPW 5GADa 4IO9W 3CMEW 1R6OC 3CCJW 3ZG0A 1K73X 4WCEW 4WFNW 3DLLW 1RQSA 3G19A 1VQPW 1QVGV 3D3IA 5CA3A 5JVGW 5GAGa 1MWSA 3G3PA 3CXCV 3PIPW 1VQQA 1MWRA 3ZG5A 1NJIX 3DNJA 1YITW 3OW2V 1VQ7W 3O1FB 1N8RX 4YKAA 4YJXA 3W7TA 1Q81X 1K8AX 1VQKW 2ZJQW 3CCEW
chains in the Genus database with same CATH topology
1KD1X 4WFAW 3CCQW 1YHQW 5GAEa 5DM7W 1S72W 1VQMW 3CCLW 1VQ4W 1VQ8W 3CPWV 1M90X 2OTJW 4IOAW 1VQOW 3CCMW 1W2BV 1YI2W 3CCSW 1Q7YX 1YIJW 1K9MX 2OTLW 4U67W 4IOCW 1JJ2V 3CC4W 4UY8Z 4WF9W 5DM6W 3CMAW 1YJNW 1VQ6W 5HL7W 2ZJRW 2QA4W 1VQNW 3I56W 1KQSV 1VQ5W 2QEXW 4WFBW 1VQ9W 3CC7W 3CD6W 5GAHa 3PIOW 1BXYA 3CCVW 3G6EW 1YJ9W 3CC2W 3CCRW 1QVFV 3G71W 1YJWW 3I55W 1KC8X 1VQLW 5JVHW 1Q86X 3G4SW 3J7ZZ 1Q82X 1M1KX 3CF5W 3CCUW 4C1NA 2ZJPW 5GADa 4IO9W 3CMEW 3CCJW 1K73X 4WCEW 4WFNW 3DLLW 1VQPW 1QVGV 5JVGW 5GAGa 3CXCV 3PIPW 1NJIX 1YITW 3OW2V 1VQ7W 1N8RX 1Q81X 1K8AX 1VQKW 2ZJQW 3CCEW
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KD1 X;  4WFA W;  3CCQ W;  1YHQ W;  5GAE a;  5DM7 W;  1S72 W;  1VQM W;  3CCL W;  1VQ4 W;  1VQ8 W;  3CPW V;  1M90 X;  2OTJ W;  4IOA W;  1VQO W;  3CCM W;  1W2B V;  1YI2 W;  3CCS W;  1Q7Y X;  1YIJ W;  1K9M X;  2OTL W;  4U67 W;  4IOC W;  1JJ2 V;  3CC4 W;  4UY8 Z;  4WF9 W;  5DM6 W;  3CMA W;  1YJN W;  1VQ6 W;  5HL7 W;  2ZJR W;  2QA4 W;  1VQN W;  3I56 W;  1KQS V;  1VQ5 W;  2QEX W;  4WFB W;  1VQ9 W;  3CC7 W;  3CD6 W;  5GAH a;  3PIO W;  1BXY A;  3CCV W;  3G6E W;  1YJ9 W;  3CC2 W;  3CCR W;  1QVF V;  3G71 W;  1YJW W;  3I55 W;  1KC8 X;  1VQL W;  5JVH W;  1Q86 X;  3G4S W;  3J7Z Z;  1Q82 X;  1M1K X;  3CF5 W;  3CCU W;  2ZJP W;  5GAD a;  4IO9 W;  3CME W;  3CCJ W;  1K73 X;  4WCE W;  4WFN W;  3DLL W;  1VQP W;  1QVG V;  5JVG W;  5GAG a;  3CXC V;  3PIP W;  1NJI X;  1YIT W;  3OW2 V;  1VQ7 W;  1N8R X;  1Q81 X;  1K8A X;  1VQK W;  2ZJQ W;  3CCE W; 
#chains in the Genus database with same CATH topology
 5M1A A;  3GW1 A;  3O2B A;  3W7W A;  1KD1 X;  4WFA W;  3CCQ W;  5M19 A;  1YHQ W;  5GAE a;  5DM7 W;  3W7U A;  5M18 A;  1S72 W;  1VQM W;  3CCL W;  1VQ4 W;  1VQ8 W;  3CPW V;  1M90 X;  2OTJ W;  4IOA W;  1VQO W;  3CCM W;  1W2B V;  1RQV A;  3G1B A;  1DD3 A;  1YI2 W;  3CCS W;  1Q7Y X;  3W7X A;  2W9R A;  1YIJ W;  1R6Q C;  2WA9 A;  4BL2 A;  1K9M X;  2OTL W;  4U67 W;  4IOC W;  1JJ2 V;  3CC4 W;  4UY8 Z;  4WF9 W;  5DM6 W;  3CMA W;  1YJN W;  3O2H A;  4BL3 A;  1MWT A;  1CTF A;  2WA8 A;  1VQ6 W;  5HL7 W;  3ZFZ A;  2QA4 W;  1VQN W;  3GQ1 A;  2ZJR W;  3I56 W;  5GW7 A;  1KQS V;  3GQ0 A;  1LZW A;  4CJN A;  1VQ5 W;  2QEX W;  4WFB W;  1VQ9 W;  3CC7 W;  3CD6 W;  5GAH a;  1MG9 A;  3PIO W;  1BXY A;  3O2O A;  3CCV W;  3G6E W;  1YJ9 W;  1MBX C;  3CCR W;  3CC2 W;  1QVF V;  3O1F A;  4YJM A;  3G71 W;  1YJW W;  1MBV B;  1MWU A;  1MBU C;  4CPK A;  1DD4 A;  3I55 W;  1KC8 X;  1VQL W;  5JVH W;  1Q86 X;  4DKI A;  3G4S W;  1RQU A;  3W7S A;  3J7Z Z;  1Q82 X;  1M1K X;  3CF5 W;  3CCU W;  4C1N A;  2ZJP W;  5GAD a;  4IO9 W;  3CME W;  1R6O C;  3CCJ W;  3ZG0 A;  1K73 X;  4WCE W;  4WFN W;  3DLL W;  1RQS A;  3G19 A;  1VQP W;  1QVG V;  3D3I A;  5CA3 A;  5JVG W;  5GAG a;  1MWS A;  3G3P A;  3CXC V;  3PIP W;  1VQQ A;  1MWR A;  3ZG5 A;  1NJI X;  3DNJ A;  1YIT W;  3OW2 V;  1VQ7 W;  3O1F B;  1N8R X;  4YKA A;  4YJX A;  3W7T A;  1Q81 X;  1K8A X;  1VQK W;  2ZJQ W;  3CCE W; 
#chains in the Genus database with same CATH homology
 1KD1 X;  4WFA W;  3CCQ W;  1YHQ W;  5GAE a;  5DM7 W;  1S72 W;  1VQM W;  3CCL W;  1VQ4 W;  1VQ8 W;  3CPW V;  1M90 X;  2OTJ W;  4IOA W;  1VQO W;  3CCM W;  1W2B V;  1YI2 W;  3CCS W;  1Q7Y X;  1YIJ W;  1K9M X;  2OTL W;  4U67 W;  4IOC W;  1JJ2 V;  3CC4 W;  4UY8 Z;  4WF9 W;  5DM6 W;  3CMA W;  1YJN W;  1VQ6 W;  5HL7 W;  2ZJR W;  2QA4 W;  1VQN W;  3I56 W;  1KQS V;  1VQ5 W;  2QEX W;  4WFB W;  1VQ9 W;  3CC7 W;  3CD6 W;  5GAH a;  3PIO W;  1BXY A;  3CCV W;  3G6E W;  1YJ9 W;  3CC2 W;  3CCR W;  1QVF V;  3G71 W;  1YJW W;  3I55 W;  1KC8 X;  1VQL W;  5JVH W;  1Q86 X;  3G4S W;  3J7Z Z;  1Q82 X;  1M1K X;  3CF5 W;  3CCU W;  4C1N A;  2ZJP W;  5GAD a;  4IO9 W;  3CME W;  3CCJ W;  1K73 X;  4WCE W;  4WFN W;  3DLL W;  1VQP W;  1QVG V;  5JVG W;  5GAG a;  3CXC V;  3PIP W;  1NJI X;  1YIT W;  3OW2 V;  1VQ7 W;  1N8R X;  1Q81 X;  1K8A X;  1VQK W;  2ZJQ W;  3CCE W; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...