3CCSW

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2482a
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 46
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3ccsW02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 3ccsW01
4UY8Z 1Q82X 1VQ6W 5JVGW 1YHQW 3CMAW 1K9MX 1YI2W 1K8AX 1QVGV 3PIPW 4IOAW 1VQKW 1VQMW 3CC7W 2QEXW 3OW2V 3CCVW 3G4SW 3CMEW 3G71W 3CCLW 1S72W 1K73X 3CCQW 5HL7W 1QVFV 3DLLW 5DM6W 3CF5W 1VQ7W 2QA4W 2ZJPW 3G6EW 3CCJW 1KQSV 1YJ9W 1YIJW 3CCEW 1YJWW 5GAGa 1VQOW 1VQPW 5GAEa 1NJIX 3I56W 1Q81X 1KC8X 1KD1X 3CD6W 4WFAW 5GAHa 4IOCW 3CCUW 3CCRW 1M1KX 3CC4W 4IO9W 1N8RX 4WF9W 1VQ5W 4U67W 5GADa 3I55W 2ZJQW 1VQ4W 1VQNW 3CXCV 4WFBW 1VQLW 4WCEW 1M90X 2OTLW 3CPWV 2OTJW 1Q7YX 4WFNW 1JJ2V 3CC2W 5DM7W 1BXYA 1W2BV 5JVHW 1YITW 1YJNW 3J7ZZ 3CCMW 2ZJRW 1VQ8W 1Q86X 1VQ9W 3PIOW 3CCSW
chains in the Genus database with same CATH superfamily
4UY8Z 4C1NA 1MBUC 3ZG0A 3GW1A 3D3IA 1DD3A 1Q82X 3W7SA 4BL2A 1VQ6W 1MWRA 4YKAA 5JVGW 1YHQW 2WA9A 1RQSA 1R6OC 3CMAW 1K9MX 1YI2W 1K8AX 3O2OA 1QVGV 3PIPW 4IOAW 1VQKW 1VQMW 3CC7W 3ZFZA 2QEXW 1MG9A 3G3PA 3OW2V 3CCVW 3G19A 3G4SW 3CMEW 1MWTA 3GQ0A 3G71W 3W7XA 3CCLW 1S72W 1K73X 5M1AA 5CA3A 1LZWA 3CCQW 5GW7A 1QVFV 1RQVA 5HL7W 1RQUA 3DLLW 5DM6W 3CF5W 1VQ7W 2QA4W 1MWSA 2ZJPW 3W7TA 3G6EW 3CCJW 1KQSV 3GQ1A 1MBXC 1YJ9W 1YIJW 3CCEW 3ZG5A 1YJWW 5GAGa 3DNJA 3O1FB 3W7WA 1VQOW 1VQPW 5GAEa 1NJIX 3I56W 1Q81X 1CTFA 1KC8X 1KD1X 3CD6W 4WFAW 1VQQA 5GAHa 4IOCW 3CCUW 3CCRW 1M1KX 3CC4W 1MWUA 3G1BA 4IO9W 1N8RX 4WF9W 1VQ5W 4U67W 5GADa 3I55W 2WA8A 2ZJQW 1VQ4W 3O2HA 1VQNW 1MBVB 3CXCV 4WFBW 1VQLW 4WCEW 4YJMA 3O1FA 1M90X 2W9RA 2OTLW 3CPWV 2OTJW 1Q7YX 4CJNA 4WFNW 1JJ2V 3CC2W 3W7UA 5DM7W 4YJXA 4BL3A 1BXYA 5M18A 4DKIA 1W2BV 5JVHW 1YITW 1DD4A 1YJNW 3J7ZZ 3CCMW 5M19A 2ZJRW 1VQ8W 1Q86X 3O2BA 1VQ9W 3PIOW 4CPKA 3CCSW 1R6QC
chains in the Genus database with same CATH topology
4UY8Z 4C1NA 1Q82X 1VQ6W 5JVGW 1YHQW 3CMAW 1K9MX 1YI2W 1K8AX 1QVGV 3PIPW 4IOAW 1VQKW 1VQMW 3CC7W 2QEXW 3OW2V 3CCVW 3G4SW 3CMEW 3G71W 3CCLW 1S72W 1K73X 3CCQW 5HL7W 1QVFV 3DLLW 5DM6W 3CF5W 1VQ7W 2QA4W 2ZJPW 3G6EW 3CCJW 1KQSV 1YJ9W 1YIJW 3CCEW 1YJWW 5GAGa 1VQOW 1VQPW 5GAEa 1NJIX 3I56W 1Q81X 1KC8X 1KD1X 3CD6W 4WFAW 5GAHa 4IOCW 3CCUW 3CCRW 1M1KX 3CC4W 4IO9W 1N8RX 4WF9W 1VQ5W 4U67W 5GADa 3I55W 2ZJQW 1VQ4W 1VQNW 3CXCV 4WFBW 1VQLW 4WCEW 1M90X 2OTLW 3CPWV 2OTJW 1Q7YX 4WFNW 1JJ2V 3CC2W 5DM7W 1BXYA 1W2BV 5JVHW 1YITW 1YJNW 3J7ZZ 3CCMW 2ZJRW 1VQ8W 1Q86X 1VQ9W 3PIOW 3CCSW
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UY8 Z;  1Q82 X;  1VQ6 W;  5JVG W;  1YHQ W;  3CMA W;  1K9M X;  1YI2 W;  1K8A X;  1QVG V;  3PIP W;  4IOA W;  1VQK W;  1VQM W;  3CC7 W;  2QEX W;  3OW2 V;  3CCV W;  3G4S W;  3CME W;  3G71 W;  3CCL W;  1S72 W;  1K73 X;  3CCQ W;  5HL7 W;  1QVF V;  3DLL W;  5DM6 W;  3CF5 W;  1VQ7 W;  2QA4 W;  2ZJP W;  3G6E W;  3CCJ W;  1KQS V;  1YJ9 W;  1YIJ W;  3CCE W;  1YJW W;  5GAG a;  1VQO W;  1VQP W;  5GAE a;  1NJI X;  3I56 W;  1Q81 X;  1KC8 X;  1KD1 X;  3CD6 W;  4WFA W;  5GAH a;  4IOC W;  3CCU W;  3CCR W;  1M1K X;  3CC4 W;  4IO9 W;  1N8R X;  4WF9 W;  1VQ5 W;  4U67 W;  5GAD a;  3I55 W;  2ZJQ W;  1VQ4 W;  1VQN W;  3CXC V;  4WFB W;  1VQL W;  4WCE W;  1M90 X;  2OTL W;  3CPW V;  2OTJ W;  1Q7Y X;  4WFN W;  1JJ2 V;  3CC2 W;  5DM7 W;  1BXY A;  1W2B V;  5JVH W;  1YIT W;  1YJN W;  3J7Z Z;  3CCM W;  2ZJR W;  1VQ8 W;  1Q86 X;  1VQ9 W;  3PIO W;  3CCS W; 
#chains in the Genus database with same CATH topology
 4UY8 Z;  4C1N A;  1MBU C;  3ZG0 A;  3GW1 A;  3D3I A;  1DD3 A;  1Q82 X;  3W7S A;  4BL2 A;  1VQ6 W;  1MWR A;  4YKA A;  5JVG W;  1YHQ W;  2WA9 A;  1RQS A;  1R6O C;  3CMA W;  1K9M X;  1YI2 W;  1K8A X;  3O2O A;  1QVG V;  3PIP W;  4IOA W;  1VQK W;  1VQM W;  3CC7 W;  3ZFZ A;  2QEX W;  1MG9 A;  3G3P A;  3OW2 V;  3CCV W;  3G19 A;  3G4S W;  3CME W;  1MWT A;  3GQ0 A;  3G71 W;  3W7X A;  3CCL W;  1S72 W;  1K73 X;  5M1A A;  5CA3 A;  1LZW A;  3CCQ W;  5GW7 A;  1QVF V;  1RQV A;  5HL7 W;  1RQU A;  3DLL W;  5DM6 W;  3CF5 W;  1VQ7 W;  2QA4 W;  1MWS A;  2ZJP W;  3W7T A;  3G6E W;  3CCJ W;  1KQS V;  3GQ1 A;  1MBX C;  1YJ9 W;  1YIJ W;  3CCE W;  3ZG5 A;  1YJW W;  5GAG a;  3DNJ A;  3O1F B;  3W7W A;  1VQO W;  1VQP W;  5GAE a;  1NJI X;  3I56 W;  1Q81 X;  1CTF A;  1KC8 X;  1KD1 X;  3CD6 W;  4WFA W;  1VQQ A;  5GAH a;  4IOC W;  3CCU W;  3CCR W;  1M1K X;  3CC4 W;  1MWU A;  3G1B A;  4IO9 W;  1N8R X;  4WF9 W;  1VQ5 W;  4U67 W;  5GAD a;  3I55 W;  2WA8 A;  2ZJQ W;  1VQ4 W;  3O2H A;  1VQN W;  1MBV B;  3CXC V;  4WFB W;  1VQL W;  4WCE W;  4YJM A;  3O1F A;  1M90 X;  2W9R A;  2OTL W;  3CPW V;  2OTJ W;  1Q7Y X;  4CJN A;  4WFN W;  1JJ2 V;  3CC2 W;  3W7U A;  5DM7 W;  4YJX A;  4BL3 A;  1BXY A;  5M18 A;  4DKI A;  1W2B V;  5JVH W;  1YIT W;  1DD4 A;  1YJN W;  3J7Z Z;  3CCM W;  5M19 A;  2ZJR W;  1VQ8 W;  1Q86 X;  3O2B A;  1VQ9 W;  3PIO W;  4CPK A;  3CCS W;  1R6Q C; 
#chains in the Genus database with same CATH homology
 4UY8 Z;  4C1N A;  1Q82 X;  1VQ6 W;  5JVG W;  1YHQ W;  3CMA W;  1K9M X;  1YI2 W;  1K8A X;  1QVG V;  3PIP W;  4IOA W;  1VQK W;  1VQM W;  3CC7 W;  2QEX W;  3OW2 V;  3CCV W;  3G4S W;  3CME W;  3G71 W;  3CCL W;  1S72 W;  1K73 X;  3CCQ W;  5HL7 W;  1QVF V;  3DLL W;  5DM6 W;  3CF5 W;  1VQ7 W;  2QA4 W;  2ZJP W;  3G6E W;  3CCJ W;  1KQS V;  1YJ9 W;  1YIJ W;  3CCE W;  1YJW W;  5GAG a;  1VQO W;  1VQP W;  5GAE a;  1NJI X;  3I56 W;  1Q81 X;  1KC8 X;  1KD1 X;  3CD6 W;  4WFA W;  5GAH a;  4IOC W;  3CCU W;  3CCR W;  1M1K X;  3CC4 W;  4IO9 W;  1N8R X;  4WF9 W;  1VQ5 W;  4U67 W;  5GAD a;  3I55 W;  2ZJQ W;  1VQ4 W;  1VQN W;  3CXC V;  4WFB W;  1VQL W;  4WCE W;  1M90 X;  2OTL W;  3CPW V;  2OTJ W;  1Q7Y X;  4WFN W;  1JJ2 V;  3CC2 W;  5DM7 W;  1BXY A;  1W2B V;  5JVH W;  1YIT W;  1YJN W;  3J7Z Z;  3CCM W;  2ZJR W;  1VQ8 W;  1Q86 X;  1VQ9 W;  3PIO W;  3CCS W; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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