4E2EA

Crystal structure of a tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide (ywhag) from homo sapiens at 2.25 a resolution
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
235
structure length
235
Chain Sequence
MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of a tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activa tion protein, gamma polypeptide (YWHAG) from Homo sapiens at 2.25 A resolution
rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords 14-3-3 protein gamma
total genus 96
structure length 235
sequence length 235
ec nomenclature
pdb deposition date 2012-03-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 4e2eA00
3IQVA 4ZQ0A 1YZ5A 5D3FA 2O8PA 4N7YA 2C23A 4DHMA 4IEAA 2C1NA 5BY9A 5J31A 2BR9A 4DX0A 3MHRA 4DHNA 5LHOA 2BTPA 1YWTA 3U9XA 1O9CA 4DNKA 2O02A 3RDHA 3IQJA 1A37A 3P1PA 5F74A 3P1RA 3P1QA 2C74A 4O46A 1A4OA 4DHPA 4JDDA 3SP5A 4QLIA 3P1OA 2B05A 1QJAA 1O9DA 4Y5IA 4Y3BA 4GNTA 1O9FA 1A38A 4N84A 4FJ3A 3NKXA 3UALA 3P1SA 4DHTA 5LU2A 3E6YA 3M51A 3AXYC 4DHUA 4F7RA 4DHSA 4FR3A 4DAUA 4WRQA 4N7GA 3SMOA 3LW1A 1QJBA 4DHQA 4IHLA 3T0MA 4DATA 4Y32A 4DHOA 2C63A 3SMNA 2BQ0A 5D2DA 5EWZA 4ZDRA 3SMLA 3UBWA 5IQPA 4JC3A 5D3EA 4BG6A 5LU1A 3SMKA 3M50A 2NPMA 3UZDA 3EFZA 2V7DA 2WH0A 3IQUA 4E2EA 5HF3A 5BTVA 3SMMA 4DHRA 3O8IA 4FL5A 4J6SA 3CU8A 3UX0A 1IB1A 3P1NA 3SPRA 4HKCA 2O98A 1O9EA 5EXAA 5LVZA 5LX2A 3T0LA 2C1JA
chains in the Genus database with same CATH superfamily
3IQVA 4ZQ0A 1YZ5A 5D3FA 2O8PA 1URJA 4N7YA 2C23A 4DHMA 4IEAA 2C1NA 5BY9A 5J31A 2BR9A 4DX0A 3MHRA 4DHNA 5LHOA 4ARYA 3EB7A 1JI6A 3X0UA 2BTPA 1YWTA 3U9XA 1O9CA 4DNKA 2O02A 3ZHEB 3RDHA 3IQJA 1A37A 3CQGA 3P1PA 5F74A 4QX1A 3I4RA 3P1QA 3P1RA 2C74A 4O46A 1A4OA 4DHPA 4JDDA 3SP5A 2C9KA 4QLIA 3P1OA 2B05A 1QJAA 1O9DA 4Y5IA 4Y3BA 4GNTA 4QX0A 1O9FA 1A38A 4N84A 4ARXA 4FJ3A 3NKXA 3UALA 3P1SA 4DHTA 4D8MA 5LU2A 3E6YA 3M51A 3AXYC 1S2XA 4DHUA 4F7RA 4DHSA 4FR3A 4DAUA 4WRQA 4N7GA 4QX2A 3CQCA 3SMOA 3LW1A 1QJBA 4DHQA 4IHLA 3T0MA 4W8JA 4DATA 4Y32A 4DHOA 2C63A 3SMNA 1DLCA 2BQ0A 5D2DA 5EWZA 4ZDRA 3SMLA 3UBWA 5IQPA 1CIYA 4JC3A 5D3EA 4BG6A 5LU1A 3SMKA 3M50A 4QX3A 2NPMA 4MOAA 3UZDA 3EFZA 2V7DA 2WH0A 3IQUA 4E2EA 5HF3A 5BTVA 3SMMA 4DHRA 1W99A 3O8IA 4FL5A 4J6SA 3CU8A 1I5PA 1IB1A 3UX0A 3P1NA 3SPRA 4HKCA 2O98A 1O9EA 5EXAA 5LVZA 5LX2A 3T0LA 2C1JA
chains in the Genus database with same CATH topology
3IQVA 4ZQ0A 1YZ5A 5D3FA 2O8PA 4N7YA 2C23A 4DHMA 4IEAA 2C1NA 5BY9A 5J31A 2BR9A 4DX0A 3MHRA 4DHNA 5LHOA 2BTPA 1YWTA 3U9XA 1O9CA 4DNKA 2O02A 3RDHA 3IQJA 1A37A 3P1PA 5F74A 3P1RA 3P1QA 2C74A 4O46A 1A4OA 4DHPA 4JDDA 3SP5A 4QLIA 3P1OA 2B05A 1QJAA 1O9DA 4Y5IA 4Y3BA 4GNTA 1O9FA 1A38A 4N84A 4FJ3A 3NKXA 3UALA 3P1SA 4DHTA 5LU2A 3E6YA 3M51A 3AXYC 4DHUA 4F7RA 4DHSA 4FR3A 4DAUA 4WRQA 4N7GA 3SMOA 3LW1A 1QJBA 4DHQA 4IHLA 3T0MA 4DATA 4Y32A 4DHOA 2C63A 3SMNA 2BQ0A 5D2DA 5EWZA 4ZDRA 3SMLA 3UBWA 5IQPA 4JC3A 5D3EA 4BG6A 5LU1A 3SMKA 3M50A 2NPMA 3UZDA 3EFZA 2V7DA 2WH0A 3IQUA 4E2EA 5HF3A 5BTVA 3SMMA 4DHRA 3O8IA 4FL5A 4J6SA 3CU8A 3UX0A 1IB1A 3P1NA 3SPRA 4HKCA 2O98A 1O9EA 5EXAA 5LVZA 5LX2A 3T0LA 2C1JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IQV A;  4ZQ0 A;  1YZ5 A;  5D3F A;  2O8P A;  4N7Y A;  2C23 A;  4DHM A;  4IEA A;  2C1N A;  5BY9 A;  5J31 A;  2BR9 A;  4DX0 A;  3MHR A;  4DHN A;  5LHO A;  2BTP A;  1YWT A;  3U9X A;  1O9C A;  4DNK A;  2O02 A;  3RDH A;  3IQJ A;  1A37 A;  3P1P A;  5F74 A;  3P1R A;  3P1Q A;  2C74 A;  4O46 A;  1A4O A;  4DHP A;  4JDD A;  3SP5 A;  4QLI A;  3P1O A;  2B05 A;  1QJA A;  1O9D A;  4Y5I A;  4Y3B A;  4GNT A;  1O9F A;  1A38 A;  4N84 A;  4FJ3 A;  3NKX A;  3UAL A;  3P1S A;  4DHT A;  5LU2 A;  3E6Y A;  3M51 A;  3AXY C;  4DHU A;  4F7R A;  4DHS A;  4FR3 A;  4DAU A;  4WRQ A;  4N7G A;  3SMO A;  3LW1 A;  1QJB A;  4DHQ A;  4IHL A;  3T0M A;  4DAT A;  4Y32 A;  4DHO A;  2C63 A;  3SMN A;  2BQ0 A;  5D2D A;  5EWZ A;  4ZDR A;  3SML A;  3UBW A;  5IQP A;  4JC3 A;  5D3E A;  4BG6 A;  5LU1 A;  3SMK A;  3M50 A;  2NPM A;  3UZD A;  3EFZ A;  2V7D A;  2WH0 A;  3IQU A;  4E2E A;  5HF3 A;  5BTV A;  3SMM A;  4DHR A;  3O8I A;  4FL5 A;  4J6S A;  3CU8 A;  3UX0 A;  1IB1 A;  3P1N A;  3SPR A;  4HKC A;  2O98 A;  1O9E A;  5EXA A;  5LVZ A;  5LX2 A;  3T0L A;  2C1J A; 
#chains in the Genus database with same CATH topology
 3IQV A;  4ZQ0 A;  1YZ5 A;  5D3F A;  2O8P A;  1URJ A;  4N7Y A;  2C23 A;  4DHM A;  4IEA A;  2C1N A;  5BY9 A;  5J31 A;  2BR9 A;  4DX0 A;  3MHR A;  4DHN A;  5LHO A;  4ARY A;  3EB7 A;  1JI6 A;  3X0U A;  2BTP A;  1YWT A;  3U9X A;  1O9C A;  4DNK A;  2O02 A;  3ZHE B;  3RDH A;  3IQJ A;  1A37 A;  3CQG A;  3P1P A;  5F74 A;  4QX1 A;  3I4R A;  3P1Q A;  3P1R A;  2C74 A;  4O46 A;  1A4O A;  4DHP A;  4JDD A;  3SP5 A;  2C9K A;  4QLI A;  3P1O A;  2B05 A;  1QJA A;  1O9D A;  4Y5I A;  4Y3B A;  4GNT A;  4QX0 A;  1O9F A;  1A38 A;  4N84 A;  4ARX A;  4FJ3 A;  3NKX A;  3UAL A;  3P1S A;  4DHT A;  4D8M A;  5LU2 A;  3E6Y A;  3M51 A;  3AXY C;  1S2X A;  4DHU A;  4F7R A;  4DHS A;  4FR3 A;  4DAU A;  4WRQ A;  4N7G A;  4QX2 A;  3CQC A;  3SMO A;  3LW1 A;  1QJB A;  4DHQ A;  4IHL A;  3T0M A;  4W8J A;  4DAT A;  4Y32 A;  4DHO A;  2C63 A;  3SMN A;  1DLC A;  2BQ0 A;  5D2D A;  5EWZ A;  4ZDR A;  3SML A;  3UBW A;  5IQP A;  1CIY A;  4JC3 A;  5D3E A;  4BG6 A;  5LU1 A;  3SMK A;  3M50 A;  4QX3 A;  2NPM A;  4MOA A;  3UZD A;  3EFZ A;  2V7D A;  2WH0 A;  3IQU A;  4E2E A;  5HF3 A;  5BTV A;  3SMM A;  4DHR A;  1W99 A;  3O8I A;  4FL5 A;  4J6S A;  3CU8 A;  1I5P A;  1IB1 A;  3UX0 A;  3P1N A;  3SPR A;  4HKC A;  2O98 A;  1O9E A;  5EXA A;  5LVZ A;  5LX2 A;  3T0L A;  2C1J A; 
#chains in the Genus database with same CATH homology
 3IQV A;  4ZQ0 A;  1YZ5 A;  5D3F A;  2O8P A;  4N7Y A;  2C23 A;  4DHM A;  4IEA A;  2C1N A;  5BY9 A;  5J31 A;  2BR9 A;  4DX0 A;  3MHR A;  4DHN A;  5LHO A;  2BTP A;  1YWT A;  3U9X A;  1O9C A;  4DNK A;  2O02 A;  3RDH A;  3IQJ A;  1A37 A;  3P1P A;  5F74 A;  3P1R A;  3P1Q A;  2C74 A;  4O46 A;  1A4O A;  4DHP A;  4JDD A;  3SP5 A;  4QLI A;  3P1O A;  2B05 A;  1QJA A;  1O9D A;  4Y5I A;  4Y3B A;  4GNT A;  1O9F A;  1A38 A;  4N84 A;  4FJ3 A;  3NKX A;  3UAL A;  3P1S A;  4DHT A;  5LU2 A;  3E6Y A;  3M51 A;  3AXY C;  4DHU A;  4F7R A;  4DHS A;  4FR3 A;  4DAU A;  4WRQ A;  4N7G A;  3SMO A;  3LW1 A;  1QJB A;  4DHQ A;  4IHL A;  3T0M A;  4DAT A;  4Y32 A;  4DHO A;  2C63 A;  3SMN A;  2BQ0 A;  5D2D A;  5EWZ A;  4ZDR A;  3SML A;  3UBW A;  5IQP A;  4JC3 A;  5D3E A;  4BG6 A;  5LU1 A;  3SMK A;  3M50 A;  2NPM A;  3UZD A;  3EFZ A;  2V7D A;  2WH0 A;  3IQU A;  4E2E A;  5HF3 A;  5BTV A;  3SMM A;  4DHR A;  3O8I A;  4FL5 A;  4J6S A;  3CU8 A;  3UX0 A;  1IB1 A;  3P1N A;  3SPR A;  4HKC A;  2O98 A;  1O9E A;  5EXA A;  5LVZ A;  5LX2 A;  3T0L A;  2C1J A; 
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