4FJ3 | Genus

Total Genus 97

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	97
sequence length	229
structure length	220
Chain Sequence	DKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELSYKDSTLIMQLLRDNLTLWTS

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Protein binding/transferase
source organism	Homo sapiens
publication title	Synergistic binding of the phosphorylated S233- and S259-binding sites of C-RAF to one 14-3-3zeta dimer pubmed doi rcsb
molecule keywords	14-3-3 protein zeta/delta
total genus	97
structure length	220
sequence length	229
chains with identical sequence	B
ec nomenclature
pdb deposition date	2012-06-11

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00244	14-3-3	14-3-3 protein

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.190.20	Mainly Alpha	Up-down Bundle	Delta-Endotoxin; domain 1	14-3-3 domain	4fj3A00

1A4OA 4DHMA 4HKCA 4N7GA 4QLIA 1O9DA 4JC3A 2C23A 4DHTA 3SMNA 2BQ0A 4FL5A 1A37A 1QJBA 3CU8A 4Y32A 2C63A 2BTPA 5D3EA 4ZQ0A 4O46A 3IQVA 3P1RA 2O8PA 3SP5A 2C1NA 2O02A 4GNTA 5F74A 4E2EA 3M51A 4N7YA 5EWZA 4DHRA 3SMKA 3O8IA 4JDDA 3SPRA 2C1JA 3RDHA 4DHOA 3IQUA 3P1OA 3P1QA 4BG6A 1O9FA 4J6SA 5LU2A 4DHPA 3E6YA 5LHOA 4FJ3A 3SMLA 4IHLA 3SMOA 3IQJA 3NKXA 4DAUA 1IB1A 5HF3A 3UX0A 1O9EA 3LW1A 5IQPA 4DNKA 3M50A 2BR9A 4DHSA 4Y3BA 2C74A 1O9CA 1A38A 5EXAA 4DHQA 4DHNA 3UBWA 4Y5IA 3P1NA 5LVZA 5J31A 3UALA 3P1PA 2B05A 5BTVA 4WRQA 3EFZA 4DX0A 4DATA 4F7RA 1YWTA 3T0MA 5D2DA 3AXYC 3T0LA 5LX2A 5LU1A 3MHRA 4DHUA 2NPMA 3SMMA 5D3FA 2V7DA 4FR3A 3UZDA 2WH0A 3P1SA 1QJAA 3U9XA 4ZDRA 4IEAA 4N84A 1YZ5A 5BY9A 2O98A
chains in the Genus database with same CATH superfamily

1A4OA 4DHMA 4HKCA 4N7GA 3ZHEB 4QLIA 1O9DA 4ARYA 4JC3A 2C23A 4W8JA 3SMNA 4DHTA 2BQ0A 4FL5A 1A37A 1QJBA 3CU8A 4Y32A 2C63A 2BTPA 5D3EA 4ZQ0A 4MOAA 4O46A 3IQVA 1I5PA 2O8PA 3P1RA 3SP5A 1JI6A 2C1NA 2O02A 4GNTA 1CIYA 5F74A 4E2EA 3M51A 3EB7A 3CQGA 4N7YA 5EWZA 4DHRA 3SMKA 3O8IA 4QX3A 4JDDA 3SPRA 2C1JA 3RDHA 4QX2A 4DHOA 3IQUA 3P1OA 3P1QA 4BG6A 1O9FA 4J6SA 5LU2A 4DHPA 3E6YA 5LHOA 4FJ3A 3SMLA 4IHLA 3SMOA 3IQJA 1URJA 3NKXA 4DAUA 1IB1A 1S2XA 5HF3A 3UX0A 1W99A 1O9EA 3LW1A 5IQPA 4DNKA 3X0UA 3M50A 4QX1A 2BR9A 4DHSA 4Y3BA 2C74A 1O9CA 1A38A 5EXAA 4DHQA 4DHNA 3UBWA 4Y5IA 3P1NA 5LVZA 5J31A 3UALA 3P1PA 2B05A 5BTVA 3EFZA 4WRQA 3I4RA 4DX0A 4DATA 4F7RA 1DLCA 1YWTA 3T0MA 5D2DA 3AXYC 3T0LA 5LX2A 5LU1A 3MHRA 4DHUA 2NPMA 3SMMA 5D3FA 2V7DA 4FR3A 3CQCA 3UZDA 4ARXA 2C9KA 4D8MA 2WH0A 3P1SA 1QJAA 3U9XA 4ZDRA 4N84A 4IEAA 1YZ5A 5BY9A 2O98A 4QX0A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1A4O A;  4DHM A;  4HKC A;  4N7G A;  4QLI A;  1O9D A;  4JC3 A;  2C23 A;  4DHT A;  3SMN A;  2BQ0 A;  4FL5 A;  1A37 A;  1QJB A;  3CU8 A;  4Y32 A;  2C63 A;  2BTP A;  5D3E A;  4ZQ0 A;  4O46 A;  3IQV A;  3P1R A;  2O8P A;  3SP5 A;  2C1N A;  2O02 A;  4GNT A;  5F74 A;  4E2E A;  3M51 A;  4N7Y A;  5EWZ A;  4DHR A;  3SMK A;  3O8I A;  4JDD A;  3SPR A;  2C1J A;  3RDH A;  4DHO A;  3IQU A;  3P1O A;  3P1Q A;  4BG6 A;  1O9F A;  4J6S A;  5LU2 A;  4DHP A;  3E6Y A;  5LHO A;  4FJ3 A;  3SML A;  4IHL A;  3SMO A;  3IQJ A;  3NKX A;  4DAU A;  1IB1 A;  5HF3 A;  3UX0 A;  1O9E A;  3LW1 A;  5IQP A;  4DNK A;  3M50 A;  2BR9 A;  4DHS A;  4Y3B A;  2C74 A;  1O9C A;  1A38 A;  5EXA A;  4DHQ A;  4DHN A;  3UBW A;  4Y5I A;  3P1N A;  5LVZ A;  5J31 A;  3UAL A;  3P1P A;  2B05 A;  5BTV A;  4WRQ A;  3EFZ A;  4DX0 A;  4DAT A;  4F7R A;  1YWT A;  3T0M A;  5D2D A;  3AXY C;  3T0L A;  5LX2 A;  5LU1 A;  3MHR A;  4DHU A;  2NPM A;  3SMM A;  5D3F A;  2V7D A;  4FR3 A;  3UZD A;  2WH0 A;  3P1S A;  1QJA A;  3U9X A;  4ZDR A;  4IEA A;  4N84 A;  1YZ5 A;  5BY9 A;  2O98 A; 
#chains in the Genus database with same CATH topology
 1A4O A;  4DHM A;  4HKC A;  4N7G A;  3ZHE B;  4QLI A;  1O9D A;  4ARY A;  4JC3 A;  2C23 A;  4W8J A;  3SMN A;  4DHT A;  2BQ0 A;  4FL5 A;  1A37 A;  1QJB A;  3CU8 A;  4Y32 A;  2C63 A;  2BTP A;  5D3E A;  4ZQ0 A;  4MOA A;  4O46 A;  3IQV A;  1I5P A;  2O8P A;  3P1R A;  3SP5 A;  1JI6 A;  2C1N A;  2O02 A;  4GNT A;  1CIY A;  5F74 A;  4E2E A;  3M51 A;  3EB7 A;  3CQG A;  4N7Y A;  5EWZ A;  4DHR A;  3SMK A;  3O8I A;  4QX3 A;  4JDD A;  3SPR A;  2C1J A;  3RDH A;  4QX2 A;  4DHO A;  3IQU A;  3P1O A;  3P1Q A;  4BG6 A;  1O9F A;  4J6S A;  5LU2 A;  4DHP A;  3E6Y A;  5LHO A;  4FJ3 A;  3SML A;  4IHL A;  3SMO A;  3IQJ A;  1URJ A;  3NKX A;  4DAU A;  1IB1 A;  1S2X A;  5HF3 A;  3UX0 A;  1W99 A;  1O9E A;  3LW1 A;  5IQP A;  4DNK A;  3X0U A;  3M50 A;  4QX1 A;  2BR9 A;  4DHS A;  4Y3B A;  2C74 A;  1O9C A;  1A38 A;  5EXA A;  4DHQ A;  4DHN A;  3UBW A;  4Y5I A;  3P1N A;  5LVZ A;  5J31 A;  3UAL A;  3P1P A;  2B05 A;  5BTV A;  3EFZ A;  4WRQ A;  3I4R A;  4DX0 A;  4DAT A;  4F7R A;  1DLC A;  1YWT A;  3T0M A;  5D2D A;  3AXY C;  3T0L A;  5LX2 A;  5LU1 A;  3MHR A;  4DHU A;  2NPM A;  3SMM A;  5D3F A;  2V7D A;  4FR3 A;  3CQC A;  3UZD A;  4ARX A;  2C9K A;  4D8M A;  2WH0 A;  3P1S A;  1QJA A;  3U9X A;  4ZDR A;  4N84 A;  4IEA A;  1YZ5 A;  5BY9 A;  2O98 A;  4QX0 A; 
#chains in the Genus database with same CATH homology
 1A4O A;  4DHM A;  4HKC A;  4N7G A;  4QLI A;  1O9D A;  4JC3 A;  2C23 A;  4DHT A;  3SMN A;  2BQ0 A;  4FL5 A;  1A37 A;  1QJB A;  3CU8 A;  4Y32 A;  2C63 A;  2BTP A;  5D3E A;  4ZQ0 A;  4O46 A;  3IQV A;  3P1R A;  2O8P A;  3SP5 A;  2C1N A;  2O02 A;  4GNT A;  5F74 A;  4E2E A;  3M51 A;  4N7Y A;  5EWZ A;  4DHR A;  3SMK A;  3O8I A;  4JDD A;  3SPR A;  2C1J A;  3RDH A;  4DHO A;  3IQU A;  3P1O A;  3P1Q A;  4BG6 A;  1O9F A;  4J6S A;  5LU2 A;  4DHP A;  3E6Y A;  5LHO A;  4FJ3 A;  3SML A;  4IHL A;  3SMO A;  3IQJ A;  3NKX A;  4DAU A;  1IB1 A;  5HF3 A;  3UX0 A;  1O9E A;  3LW1 A;  5IQP A;  4DNK A;  3M50 A;  2BR9 A;  4DHS A;  4Y3B A;  2C74 A;  1O9C A;  1A38 A;  5EXA A;  4DHQ A;  4DHN A;  3UBW A;  4Y5I A;  3P1N A;  5LVZ A;  5J31 A;  3UAL A;  3P1P A;  2B05 A;  5BTV A;  4WRQ A;  3EFZ A;  4DX0 A;  4DAT A;  4F7R A;  1YWT A;  3T0M A;  5D2D A;  3AXY C;  3T0L A;  5LX2 A;  5LU1 A;  3MHR A;  4DHU A;  2NPM A;  3SMM A;  5D3F A;  2V7D A;  4FR3 A;  3UZD A;  2WH0 A;  3P1S A;  1QJA A;  3U9X A;  4ZDR A;  4IEA A;  4N84 A;  1YZ5 A;  5BY9 A;  2O98 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4FJ3A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations