4JDD | Genus

Total Genus 99

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	99
sequence length	236
structure length	236
Chain Sequence	GAMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Signaling protein/peptide
source organism	Homo sapiens
publication title	Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface. pubmed doi rcsb
molecule keywords	14-3-3 protein sigma
total genus	99
structure length	236
sequence length	236
ec nomenclature
pdb deposition date	2013-02-25

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00244	14-3-3	14-3-3 protein

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.190.20	Mainly Alpha	Up-down Bundle	Delta-Endotoxin; domain 1	14-3-3 domain	4jddA00

3SMLA 4Y5IA 4DHSA 2BTPA 1O9FA 4E2EA 4IEAA 4HKCA 3CU8A 3E6YA 1A4OA 3P1PA 3T0MA 2C63A 4FL5A 3M50A 3T0LA 3NKXA 4F7RA 3SPRA 4DHMA 5D3FA 4Y3BA 1QJBA 5LU2A 4IHLA 5LX2A 5LVZA 5D2DA 4DHRA 3SMNA 4DHNA 2B05A 3P1SA 4DHQA 4QLIA 4WRQA 2NPMA 1YWTA 3U9XA 3SP5A 4ZDRA 5BTVA 4DHOA 1QJAA 5EXAA 3M51A 4DHUA 3UZDA 2O8PA 4GNTA 5EWZA 4J6SA 3SMKA 3LW1A 1O9EA 1IB1A 3P1QA 4JDDA 3IQVA 5D3EA 2C74A 4DX0A 3UBWA 4FR3A 4N7GA 3SMOA 3P1NA 1YZ5A 5IQPA 2O98A 1A38A 5LHOA 3EFZA 2C23A 2WH0A 3AXYC 2O02A 5HF3A 1O9CA 4N7YA 3IQUA 5F74A 4DNKA 4DAUA 3UX0A 1O9DA 3IQJA 1A37A 5BY9A 5J31A 2C1JA 3MHRA 3RDHA 3O8IA 4JC3A 2V7DA 2BR9A 3SMMA 2BQ0A 3P1OA 3UALA 4N84A 4DATA 4O46A 2C1NA 5LU1A 4DHPA 4Y32A 4DHTA 4ZQ0A 4BG6A 3P1RA 4FJ3A
chains in the Genus database with same CATH superfamily

3SMLA 4Y5IA 4DHSA 2BTPA 1O9FA 4E2EA 4IEAA 4HKCA 3X0UA 4D8MA 3CU8A 3E6YA 1A4OA 3P1PA 3T0MA 2C63A 4FL5A 3M50A 2C9KA 3T0LA 3NKXA 1URJA 4QX3A 4F7RA 4ARYA 4MOAA 3SPRA 4DHMA 5D3FA 4Y3BA 1QJBA 5LU2A 4IHLA 5LX2A 5LVZA 5D2DA 4DHRA 3SMNA 4DHNA 2B05A 3P1SA 4DHQA 4QLIA 4WRQA 2NPMA 1W99A 1YWTA 3U9XA 3SP5A 4QX2A 4ZDRA 5BTVA 4DHOA 1QJAA 5EXAA 3ZHEB 3M51A 4DHUA 1JI6A 3UZDA 2O8PA 4GNTA 5EWZA 4J6SA 1CIYA 3LW1A 3IQVA 1O9EA 1IB1A 3P1QA 4JDDA 3SMKA 4ARXA 5D3EA 2C74A 4DX0A 3UBWA 4FR3A 4N7GA 3SMOA 3P1NA 4W8JA 1YZ5A 1S2XA 1I5PA 5IQPA 2O98A 1A38A 5LHOA 3EFZA 3EB7A 2C23A 2WH0A 3AXYC 3CQGA 2O02A 5HF3A 1O9CA 4N7YA 3IQUA 5F74A 4DNKA 4DAUA 3UX0A 1O9DA 3IQJA 3I4RA 1A37A 5BY9A 5J31A 2C1JA 1DLCA 3MHRA 3O8IA 3RDHA 4JC3A 2V7DA 2BR9A 3SMMA 2BQ0A 3P1OA 3UALA 4N84A 4QX0A 4DATA 4QX1A 4O46A 2C1NA 3CQCA 5LU1A 4DHPA 4Y32A 4DHTA 4ZQ0A 4BG6A 3P1RA 4FJ3A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3SML A;  4Y5I A;  4DHS A;  2BTP A;  1O9F A;  4E2E A;  4IEA A;  4HKC A;  3CU8 A;  3E6Y A;  1A4O A;  3P1P A;  3T0M A;  2C63 A;  4FL5 A;  3M50 A;  3T0L A;  3NKX A;  4F7R A;  3SPR A;  4DHM A;  5D3F A;  4Y3B A;  1QJB A;  5LU2 A;  4IHL A;  5LX2 A;  5LVZ A;  5D2D A;  4DHR A;  3SMN A;  4DHN A;  2B05 A;  3P1S A;  4DHQ A;  4QLI A;  4WRQ A;  2NPM A;  1YWT A;  3U9X A;  3SP5 A;  4ZDR A;  5BTV A;  4DHO A;  1QJA A;  5EXA A;  3M51 A;  4DHU A;  3UZD A;  2O8P A;  4GNT A;  5EWZ A;  4J6S A;  3SMK A;  3LW1 A;  1O9E A;  1IB1 A;  3P1Q A;  4JDD A;  3IQV A;  5D3E A;  2C74 A;  4DX0 A;  3UBW A;  4FR3 A;  4N7G A;  3SMO A;  3P1N A;  1YZ5 A;  5IQP A;  2O98 A;  1A38 A;  5LHO A;  3EFZ A;  2C23 A;  2WH0 A;  3AXY C;  2O02 A;  5HF3 A;  1O9C A;  4N7Y A;  3IQU A;  5F74 A;  4DNK A;  4DAU A;  3UX0 A;  1O9D A;  3IQJ A;  1A37 A;  5BY9 A;  5J31 A;  2C1J A;  3MHR A;  3RDH A;  3O8I A;  4JC3 A;  2V7D A;  2BR9 A;  3SMM A;  2BQ0 A;  3P1O A;  3UAL A;  4N84 A;  4DAT A;  4O46 A;  2C1N A;  5LU1 A;  4DHP A;  4Y32 A;  4DHT A;  4ZQ0 A;  4BG6 A;  3P1R A;  4FJ3 A; 
#chains in the Genus database with same CATH topology
 3SML A;  4Y5I A;  4DHS A;  2BTP A;  1O9F A;  4E2E A;  4IEA A;  4HKC A;  3X0U A;  4D8M A;  3CU8 A;  3E6Y A;  1A4O A;  3P1P A;  3T0M A;  2C63 A;  4FL5 A;  3M50 A;  2C9K A;  3T0L A;  3NKX A;  1URJ A;  4QX3 A;  4F7R A;  4ARY A;  4MOA A;  3SPR A;  4DHM A;  5D3F A;  4Y3B A;  1QJB A;  5LU2 A;  4IHL A;  5LX2 A;  5LVZ A;  5D2D A;  4DHR A;  3SMN A;  4DHN A;  2B05 A;  3P1S A;  4DHQ A;  4QLI A;  4WRQ A;  2NPM A;  1W99 A;  1YWT A;  3U9X A;  3SP5 A;  4QX2 A;  4ZDR A;  5BTV A;  4DHO A;  1QJA A;  5EXA A;  3ZHE B;  3M51 A;  4DHU A;  1JI6 A;  3UZD A;  2O8P A;  4GNT A;  5EWZ A;  4J6S A;  1CIY A;  3LW1 A;  3IQV A;  1O9E A;  1IB1 A;  3P1Q A;  4JDD A;  3SMK A;  4ARX A;  5D3E A;  2C74 A;  4DX0 A;  3UBW A;  4FR3 A;  4N7G A;  3SMO A;  3P1N A;  4W8J A;  1YZ5 A;  1S2X A;  1I5P A;  5IQP A;  2O98 A;  1A38 A;  5LHO A;  3EFZ A;  3EB7 A;  2C23 A;  2WH0 A;  3AXY C;  3CQG A;  2O02 A;  5HF3 A;  1O9C A;  4N7Y A;  3IQU A;  5F74 A;  4DNK A;  4DAU A;  3UX0 A;  1O9D A;  3IQJ A;  3I4R A;  1A37 A;  5BY9 A;  5J31 A;  2C1J A;  1DLC A;  3MHR A;  3O8I A;  3RDH A;  4JC3 A;  2V7D A;  2BR9 A;  3SMM A;  2BQ0 A;  3P1O A;  3UAL A;  4N84 A;  4QX0 A;  4DAT A;  4QX1 A;  4O46 A;  2C1N A;  3CQC A;  5LU1 A;  4DHP A;  4Y32 A;  4DHT A;  4ZQ0 A;  4BG6 A;  3P1R A;  4FJ3 A; 
#chains in the Genus database with same CATH homology
 3SML A;  4Y5I A;  4DHS A;  2BTP A;  1O9F A;  4E2E A;  4IEA A;  4HKC A;  3CU8 A;  3E6Y A;  1A4O A;  3P1P A;  3T0M A;  2C63 A;  4FL5 A;  3M50 A;  3T0L A;  3NKX A;  4F7R A;  3SPR A;  4DHM A;  5D3F A;  4Y3B A;  1QJB A;  5LU2 A;  4IHL A;  5LX2 A;  5LVZ A;  5D2D A;  4DHR A;  3SMN A;  4DHN A;  2B05 A;  3P1S A;  4DHQ A;  4QLI A;  4WRQ A;  2NPM A;  1YWT A;  3U9X A;  3SP5 A;  4ZDR A;  5BTV A;  4DHO A;  1QJA A;  5EXA A;  3M51 A;  4DHU A;  3UZD A;  2O8P A;  4GNT A;  5EWZ A;  4J6S A;  3SMK A;  3LW1 A;  1O9E A;  1IB1 A;  3P1Q A;  4JDD A;  3IQV A;  5D3E A;  2C74 A;  4DX0 A;  3UBW A;  4FR3 A;  4N7G A;  3SMO A;  3P1N A;  1YZ5 A;  5IQP A;  2O98 A;  1A38 A;  5LHO A;  3EFZ A;  2C23 A;  2WH0 A;  3AXY C;  2O02 A;  5HF3 A;  1O9C A;  4N7Y A;  3IQU A;  5F74 A;  4DNK A;  4DAU A;  3UX0 A;  1O9D A;  3IQJ A;  1A37 A;  5BY9 A;  5J31 A;  2C1J A;  3MHR A;  3RDH A;  3O8I A;  4JC3 A;  2V7D A;  2BR9 A;  3SMM A;  2BQ0 A;  3P1O A;  3UAL A;  4N84 A;  4DAT A;  4O46 A;  2C1N A;  5LU1 A;  4DHP A;  4Y32 A;  4DHT A;  4ZQ0 A;  4BG6 A;  3P1R A;  4FJ3 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4JDDA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations