4N7Y | Genus

Total Genus 95

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	95
sequence length	230
structure length	230
Chain Sequence	MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTS

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Signaling protein
source organism	Homo sapiens
publication title	Constrained peptides with target-adapted cross-links as inhibitors of a pathogenic protein-protein interaction. pubmed doi rcsb
molecule keywords	14-3-3 protein zeta/delta
total genus	95
structure length	230
sequence length	230
chains with identical sequence	B
ec nomenclature
pdb deposition date	2013-10-16

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00244	14-3-3	14-3-3 protein

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.190.20	Mainly Alpha	Up-down Bundle	Delta-Endotoxin; domain 1	14-3-3 domain	4n7yA00

5EXAA 3P1NA 3SP5A 4F7RA 4ZQ0A 3SMLA 1O9CA 5EWZA 4DHTA 1YWTA 1O9FA 2V7DA 4IEAA 3UALA 3UX0A 3P1QA 2C74A 3SMKA 2WH0A 2B05A 4QLIA 3M50A 4E2EA 2O8PA 4BG6A 5D2DA 5IQPA 5BTVA 4WRQA 1IB1A 3O8IA 3RDHA 2BTPA 2O98A 4GNTA 3CU8A 4DHSA 4JC3A 3MHRA 3P1OA 2NPMA 4DHOA 5D3FA 2C63A 4DHNA 3SPRA 2O02A 4N7GA 2C1JA 4Y3BA 5LU2A 5LX2A 4Y32A 2BR9A 1A4OA 4FR3A 3SMMA 4N7YA 4DAUA 1QJAA 3IQJA 4FL5A 3SMNA 3NKXA 5LHOA 4J6SA 4HKCA 5LU1A 1A37A 4JDDA 3AXYC 5BY9A 4O46A 4ZDRA 2C23A 2C1NA 4N84A 4DNKA 3IQUA 3P1PA 1A38A 3SMOA 4FJ3A 5LVZA 1O9DA 4DHRA 3T0MA 3UZDA 2BQ0A 3E6YA 3P1RA 4IHLA 4DHQA 5HF3A 5J31A 4DHPA 4DATA 3T0LA 1YZ5A 5F74A 5D3EA 4DX0A 4DHUA 1QJBA 3M51A 3LW1A 3P1SA 1O9EA 4Y5IA 3EFZA 3IQVA 3UBWA 3U9XA 4DHMA
chains in the Genus database with same CATH superfamily

5EXAA 3P1NA 3SP5A 4F7RA 4ZQ0A 2C9KA 3SMLA 1O9CA 5EWZA 4DHTA 1YWTA 1O9FA 2V7DA 4IEAA 3UALA 3UX0A 1CIYA 3P1QA 2C74A 3SMKA 2WH0A 4ARYA 2B05A 4QLIA 3M50A 4E2EA 2O8PA 4BG6A 5D2DA 5IQPA 4ARXA 5BTVA 4WRQA 3O8IA 1IB1A 1S2XA 3RDHA 2BTPA 2O98A 4GNTA 4W8JA 4D8MA 3CU8A 4DHSA 4JC3A 3MHRA 3P1OA 2NPMA 4DHOA 5D3FA 4QX2A 2C63A 4DHNA 3SPRA 2O02A 4N7GA 2C1JA 3CQGA 4Y3BA 5LU2A 1I5PA 5LX2A 4Y32A 2BR9A 1A4OA 4FR3A 3I4RA 3SMMA 4N7YA 4DAUA 1QJAA 3IQJA 4FL5A 3SMNA 3NKXA 5LHOA 4J6SA 4HKCA 4QX3A 5LU1A 1A37A 4JDDA 3CQCA 3AXYC 3EB7A 5BY9A 1URJA 3X0UA 4O46A 4ZDRA 2C23A 2C1NA 4N84A 4DNKA 3IQUA 3P1PA 1A38A 3SMOA 4FJ3A 1JI6A 5LVZA 1W99A 1O9DA 4DHRA 3T0MA 3UZDA 1DLCA 2BQ0A 3E6YA 3P1RA 4IHLA 3ZHEB 4DHQA 5HF3A 5J31A 4DHPA 4DATA 3T0LA 1YZ5A 4QX1A 5F74A 5D3EA 4DX0A 4DHUA 1QJBA 3M51A 3LW1A 3P1SA 1O9EA 4Y5IA 3EFZA 3IQVA 3UBWA 3U9XA 4QX0A 4DHMA 4MOAA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 5EXA A;  3P1N A;  3SP5 A;  4F7R A;  4ZQ0 A;  3SML A;  1O9C A;  5EWZ A;  4DHT A;  1YWT A;  1O9F A;  2V7D A;  4IEA A;  3UAL A;  3UX0 A;  3P1Q A;  2C74 A;  3SMK A;  2WH0 A;  2B05 A;  4QLI A;  3M50 A;  4E2E A;  2O8P A;  4BG6 A;  5D2D A;  5IQP A;  5BTV A;  4WRQ A;  1IB1 A;  3O8I A;  3RDH A;  2BTP A;  2O98 A;  4GNT A;  3CU8 A;  4DHS A;  4JC3 A;  3MHR A;  3P1O A;  2NPM A;  4DHO A;  5D3F A;  2C63 A;  4DHN A;  3SPR A;  2O02 A;  4N7G A;  2C1J A;  4Y3B A;  5LU2 A;  5LX2 A;  4Y32 A;  2BR9 A;  1A4O A;  4FR3 A;  3SMM A;  4N7Y A;  4DAU A;  1QJA A;  3IQJ A;  4FL5 A;  3SMN A;  3NKX A;  5LHO A;  4J6S A;  4HKC A;  5LU1 A;  1A37 A;  4JDD A;  3AXY C;  5BY9 A;  4O46 A;  4ZDR A;  2C23 A;  2C1N A;  4N84 A;  4DNK A;  3IQU A;  3P1P A;  1A38 A;  3SMO A;  4FJ3 A;  5LVZ A;  1O9D A;  4DHR A;  3T0M A;  3UZD A;  2BQ0 A;  3E6Y A;  3P1R A;  4IHL A;  4DHQ A;  5HF3 A;  5J31 A;  4DHP A;  4DAT A;  3T0L A;  1YZ5 A;  5F74 A;  5D3E A;  4DX0 A;  4DHU A;  1QJB A;  3M51 A;  3LW1 A;  3P1S A;  1O9E A;  4Y5I A;  3EFZ A;  3IQV A;  3UBW A;  3U9X A;  4DHM A; 
#chains in the Genus database with same CATH topology
 5EXA A;  3P1N A;  3SP5 A;  4F7R A;  4ZQ0 A;  2C9K A;  3SML A;  1O9C A;  5EWZ A;  4DHT A;  1YWT A;  1O9F A;  2V7D A;  4IEA A;  3UAL A;  3UX0 A;  1CIY A;  3P1Q A;  2C74 A;  3SMK A;  2WH0 A;  4ARY A;  2B05 A;  4QLI A;  3M50 A;  4E2E A;  2O8P A;  4BG6 A;  5D2D A;  5IQP A;  4ARX A;  5BTV A;  4WRQ A;  3O8I A;  1IB1 A;  1S2X A;  3RDH A;  2BTP A;  2O98 A;  4GNT A;  4W8J A;  4D8M A;  3CU8 A;  4DHS A;  4JC3 A;  3MHR A;  3P1O A;  2NPM A;  4DHO A;  5D3F A;  4QX2 A;  2C63 A;  4DHN A;  3SPR A;  2O02 A;  4N7G A;  2C1J A;  3CQG A;  4Y3B A;  5LU2 A;  1I5P A;  5LX2 A;  4Y32 A;  2BR9 A;  1A4O A;  4FR3 A;  3I4R A;  3SMM A;  4N7Y A;  4DAU A;  1QJA A;  3IQJ A;  4FL5 A;  3SMN A;  3NKX A;  5LHO A;  4J6S A;  4HKC A;  4QX3 A;  5LU1 A;  1A37 A;  4JDD A;  3CQC A;  3AXY C;  3EB7 A;  5BY9 A;  1URJ A;  3X0U A;  4O46 A;  4ZDR A;  2C23 A;  2C1N A;  4N84 A;  4DNK A;  3IQU A;  3P1P A;  1A38 A;  3SMO A;  4FJ3 A;  1JI6 A;  5LVZ A;  1W99 A;  1O9D A;  4DHR A;  3T0M A;  3UZD A;  1DLC A;  2BQ0 A;  3E6Y A;  3P1R A;  4IHL A;  3ZHE B;  4DHQ A;  5HF3 A;  5J31 A;  4DHP A;  4DAT A;  3T0L A;  1YZ5 A;  4QX1 A;  5F74 A;  5D3E A;  4DX0 A;  4DHU A;  1QJB A;  3M51 A;  3LW1 A;  3P1S A;  1O9E A;  4Y5I A;  3EFZ A;  3IQV A;  3UBW A;  3U9X A;  4QX0 A;  4DHM A;  4MOA A; 
#chains in the Genus database with same CATH homology
 5EXA A;  3P1N A;  3SP5 A;  4F7R A;  4ZQ0 A;  3SML A;  1O9C A;  5EWZ A;  4DHT A;  1YWT A;  1O9F A;  2V7D A;  4IEA A;  3UAL A;  3UX0 A;  3P1Q A;  2C74 A;  3SMK A;  2WH0 A;  2B05 A;  4QLI A;  3M50 A;  4E2E A;  2O8P A;  4BG6 A;  5D2D A;  5IQP A;  5BTV A;  4WRQ A;  1IB1 A;  3O8I A;  3RDH A;  2BTP A;  2O98 A;  4GNT A;  3CU8 A;  4DHS A;  4JC3 A;  3MHR A;  3P1O A;  2NPM A;  4DHO A;  5D3F A;  2C63 A;  4DHN A;  3SPR A;  2O02 A;  4N7G A;  2C1J A;  4Y3B A;  5LU2 A;  5LX2 A;  4Y32 A;  2BR9 A;  1A4O A;  4FR3 A;  3SMM A;  4N7Y A;  4DAU A;  1QJA A;  3IQJ A;  4FL5 A;  3SMN A;  3NKX A;  5LHO A;  4J6S A;  4HKC A;  5LU1 A;  1A37 A;  4JDD A;  3AXY C;  5BY9 A;  4O46 A;  4ZDR A;  2C23 A;  2C1N A;  4N84 A;  4DNK A;  3IQU A;  3P1P A;  1A38 A;  3SMO A;  4FJ3 A;  5LVZ A;  1O9D A;  4DHR A;  3T0M A;  3UZD A;  2BQ0 A;  3E6Y A;  3P1R A;  4IHL A;  4DHQ A;  5HF3 A;  5J31 A;  4DHP A;  4DAT A;  3T0L A;  1YZ5 A;  5F74 A;  5D3E A;  4DX0 A;  4DHU A;  1QJB A;  3M51 A;  3LW1 A;  3P1S A;  1O9E A;  4Y5I A;  3EFZ A;  3IQV A;  3UBW A;  3U9X A;  4DHM A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4N7YA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations