5LU1 | Genus

Total Genus 95

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	95
sequence length	230
structure length	225
Chain Sequence	ERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEAGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Signaling protein
source organism	Homo sapiens
publication title	Structural Basis for the Interaction of a Human Small Heat Shock Protein with the 14-3-3 Universal Signaling Regulator. pubmed doi rcsb
molecule keywords	14-3-3 protein sigma
total genus	95
structure length	225
sequence length	230
chains with identical sequence	B, E, F
ec nomenclature
pdb deposition date	2016-09-07

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00244	14-3-3	14-3-3 protein

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.190.20	Mainly Alpha	Up-down Bundle	Delta-Endotoxin; domain 1	14-3-3 domain	5lu1A00

2O8PA 3IQVA 4DNKA 3IQUA 3P1QA 2C1JA 4ZDRA 1YWTA 1A38A 3M51A 4DHPA 4F7RA 3CU8A 4JDDA 3AXYC 3SMMA 3MHRA 1QJAA 2NPMA 3E6YA 5LX2A 2C63A 1YZ5A 5LHOA 1A37A 4JC3A 5IQPA 4DHOA 4BG6A 4Y32A 1IB1A 1O9EA 4DHNA 3U9XA 5LU2A 5J31A 4DHUA 2O98A 5LU1A 5D3FA 3SP5A 4E2EA 4FR3A 2BQ0A 4DHTA 4IEAA 3UALA 4DAUA 5HF3A 4DHRA 3O8IA 4O46A 3P1RA 1O9CA 2BTPA 4QLIA 1O9FA 3P1PA 4WRQA 3SMOA 4Y3BA 4FL5A 2O02A 4IHLA 5F74A 3UZDA 3M50A 4DATA 5LVZA 3SPRA 2C23A 3SMNA 3T0MA 3P1NA 4N7GA 3IQJA 4DHSA 5BTVA 3NKXA 3RDHA 5D2DA 2V7DA 4J6SA 5EXAA 3P1SA 4GNTA 4ZQ0A 4FJ3A 3UBWA 4DHMA 2BR9A 4HKCA 2WH0A 3UX0A 4Y5IA 3EFZA 4N84A 3SMLA 3P1OA 4N7YA 5D3EA 1O9DA 2C1NA 3LW1A 5EWZA 1QJBA 2C74A 4DHQA 2B05A 5BY9A 1A4OA 3SMKA 3T0LA 4DX0A
chains in the Genus database with same CATH superfamily

2O8PA 3IQVA 4DNKA 3IQUA 3P1QA 2C1JA 4ZDRA 1YWTA 1A38A 3CQGA 3M51A 4DHPA 4F7RA 1S2XA 3CU8A 4JDDA 3AXYC 1I5PA 3SMMA 3MHRA 1QJAA 2NPMA 3E6YA 5LX2A 2C63A 1YZ5A 1W99A 5LHOA 1A37A 4JC3A 5IQPA 4DHOA 4BG6A 4Y32A 1IB1A 3CQCA 1O9EA 4DHNA 3U9XA 5LU2A 4D8MA 5J31A 4DHUA 2O98A 4QX2A 5LU1A 5D3FA 3SP5A 4E2EA 4FR3A 2BQ0A 1DLCA 4DHTA 4IEAA 3UALA 4DAUA 4QX3A 5HF3A 4DHRA 4MOAA 3O8IA 4O46A 1JI6A 3P1RA 1O9CA 2BTPA 4QLIA 1O9FA 3P1PA 4ARYA 4WRQA 3SMOA 4Y3BA 4FL5A 2O02A 4IHLA 5F74A 3UZDA 3M50A 4DATA 5LVZA 3EB7A 3ZHEB 3SPRA 2C23A 3SMNA 3T0MA 3P1NA 4N7GA 3IQJA 4DHSA 5BTVA 3NKXA 3RDHA 5D2DA 2V7DA 4J6SA 5EXAA 3P1SA 1URJA 4GNTA 3X0UA 4ZQ0A 4FJ3A 3UBWA 4DHMA 2BR9A 4HKCA 2WH0A 3UX0A 4Y5IA 3EFZA 4N84A 3SMLA 2C9KA 3I4RA 3P1OA 4N7YA 5D3EA 1O9DA 2C1NA 3LW1A 4W8JA 4QX0A 1QJBA 5EWZA 2C74A 4DHQA 2B05A 4ARXA 5BY9A 1A4OA 3SMKA 4QX1A 3T0LA 4DX0A 1CIYA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2O8P A;  3IQV A;  4DNK A;  3IQU A;  3P1Q A;  2C1J A;  4ZDR A;  1YWT A;  1A38 A;  3M51 A;  4DHP A;  4F7R A;  3CU8 A;  4JDD A;  3AXY C;  3SMM A;  3MHR A;  1QJA A;  2NPM A;  3E6Y A;  5LX2 A;  2C63 A;  1YZ5 A;  5LHO A;  1A37 A;  4JC3 A;  5IQP A;  4DHO A;  4BG6 A;  4Y32 A;  1IB1 A;  1O9E A;  4DHN A;  3U9X A;  5LU2 A;  5J31 A;  4DHU A;  2O98 A;  5LU1 A;  5D3F A;  3SP5 A;  4E2E A;  4FR3 A;  2BQ0 A;  4DHT A;  4IEA A;  3UAL A;  4DAU A;  5HF3 A;  4DHR A;  3O8I A;  4O46 A;  3P1R A;  1O9C A;  2BTP A;  4QLI A;  1O9F A;  3P1P A;  4WRQ A;  3SMO A;  4Y3B A;  4FL5 A;  2O02 A;  4IHL A;  5F74 A;  3UZD A;  3M50 A;  4DAT A;  5LVZ A;  3SPR A;  2C23 A;  3SMN A;  3T0M A;  3P1N A;  4N7G A;  3IQJ A;  4DHS A;  5BTV A;  3NKX A;  3RDH A;  5D2D A;  2V7D A;  4J6S A;  5EXA A;  3P1S A;  4GNT A;  4ZQ0 A;  4FJ3 A;  3UBW A;  4DHM A;  2BR9 A;  4HKC A;  2WH0 A;  3UX0 A;  4Y5I A;  3EFZ A;  4N84 A;  3SML A;  3P1O A;  4N7Y A;  5D3E A;  1O9D A;  2C1N A;  3LW1 A;  5EWZ A;  1QJB A;  2C74 A;  4DHQ A;  2B05 A;  5BY9 A;  1A4O A;  3SMK A;  3T0L A;  4DX0 A; 
#chains in the Genus database with same CATH topology
 2O8P A;  3IQV A;  4DNK A;  3IQU A;  3P1Q A;  2C1J A;  4ZDR A;  1YWT A;  1A38 A;  3CQG A;  3M51 A;  4DHP A;  4F7R A;  1S2X A;  3CU8 A;  4JDD A;  3AXY C;  1I5P A;  3SMM A;  3MHR A;  1QJA A;  2NPM A;  3E6Y A;  5LX2 A;  2C63 A;  1YZ5 A;  1W99 A;  5LHO A;  1A37 A;  4JC3 A;  5IQP A;  4DHO A;  4BG6 A;  4Y32 A;  1IB1 A;  3CQC A;  1O9E A;  4DHN A;  3U9X A;  5LU2 A;  4D8M A;  5J31 A;  4DHU A;  2O98 A;  4QX2 A;  5LU1 A;  5D3F A;  3SP5 A;  4E2E A;  4FR3 A;  2BQ0 A;  1DLC A;  4DHT A;  4IEA A;  3UAL A;  4DAU A;  4QX3 A;  5HF3 A;  4DHR A;  4MOA A;  3O8I A;  4O46 A;  1JI6 A;  3P1R A;  1O9C A;  2BTP A;  4QLI A;  1O9F A;  3P1P A;  4ARY A;  4WRQ A;  3SMO A;  4Y3B A;  4FL5 A;  2O02 A;  4IHL A;  5F74 A;  3UZD A;  3M50 A;  4DAT A;  5LVZ A;  3EB7 A;  3ZHE B;  3SPR A;  2C23 A;  3SMN A;  3T0M A;  3P1N A;  4N7G A;  3IQJ A;  4DHS A;  5BTV A;  3NKX A;  3RDH A;  5D2D A;  2V7D A;  4J6S A;  5EXA A;  3P1S A;  1URJ A;  4GNT A;  3X0U A;  4ZQ0 A;  4FJ3 A;  3UBW A;  4DHM A;  2BR9 A;  4HKC A;  2WH0 A;  3UX0 A;  4Y5I A;  3EFZ A;  4N84 A;  3SML A;  2C9K A;  3I4R A;  3P1O A;  4N7Y A;  5D3E A;  1O9D A;  2C1N A;  3LW1 A;  4W8J A;  4QX0 A;  1QJB A;  5EWZ A;  2C74 A;  4DHQ A;  2B05 A;  4ARX A;  5BY9 A;  1A4O A;  3SMK A;  4QX1 A;  3T0L A;  4DX0 A;  1CIY A; 
#chains in the Genus database with same CATH homology
 2O8P A;  3IQV A;  4DNK A;  3IQU A;  3P1Q A;  2C1J A;  4ZDR A;  1YWT A;  1A38 A;  3M51 A;  4DHP A;  4F7R A;  3CU8 A;  4JDD A;  3AXY C;  3SMM A;  3MHR A;  1QJA A;  2NPM A;  3E6Y A;  5LX2 A;  2C63 A;  1YZ5 A;  5LHO A;  1A37 A;  4JC3 A;  5IQP A;  4DHO A;  4BG6 A;  4Y32 A;  1IB1 A;  1O9E A;  4DHN A;  3U9X A;  5LU2 A;  5J31 A;  4DHU A;  2O98 A;  5LU1 A;  5D3F A;  3SP5 A;  4E2E A;  4FR3 A;  2BQ0 A;  4DHT A;  4IEA A;  3UAL A;  4DAU A;  5HF3 A;  4DHR A;  3O8I A;  4O46 A;  3P1R A;  1O9C A;  2BTP A;  4QLI A;  1O9F A;  3P1P A;  4WRQ A;  3SMO A;  4Y3B A;  4FL5 A;  2O02 A;  4IHL A;  5F74 A;  3UZD A;  3M50 A;  4DAT A;  5LVZ A;  3SPR A;  2C23 A;  3SMN A;  3T0M A;  3P1N A;  4N7G A;  3IQJ A;  4DHS A;  5BTV A;  3NKX A;  3RDH A;  5D2D A;  2V7D A;  4J6S A;  5EXA A;  3P1S A;  4GNT A;  4ZQ0 A;  4FJ3 A;  3UBW A;  4DHM A;  2BR9 A;  4HKC A;  2WH0 A;  3UX0 A;  4Y5I A;  3EFZ A;  4N84 A;  3SML A;  3P1O A;  4N7Y A;  5D3E A;  1O9D A;  2C1N A;  3LW1 A;  5EWZ A;  1QJB A;  2C74 A;  4DHQ A;  2B05 A;  5BY9 A;  1A4O A;  3SMK A;  3T0L A;  4DX0 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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5LU1A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations