5LU1A

Human 14-3-3 sigma clu3 mutant complexed with short hspb6 phosphopeptide
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
230
structure length
225
Chain Sequence
ERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEAGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for the Interaction of a Human Small Heat Shock Protein with the 14-3-3 Universal Signaling Regulator.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords 14-3-3 protein sigma
total genus 95
structure length 225
sequence length 230
chains with identical sequence B, E, F
ec nomenclature
pdb deposition date 2016-09-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 5lu1A00
4F7RA 3AXYC 3P1RA 3U9XA 2NPMA 4ZDRA 1YZ5A 3P1QA 2C23A 5LU2A 3E6YA 4DNKA 3SP5A 3UALA 4DHOA 4DHUA 4DAUA 3M50A 4HKCA 3SPRA 4J6SA 1A38A 4N84A 5LX2A 4QLIA 5J31A 1O9DA 1O9EA 5BTVA 2BQ0A 4WRQA 3T0MA 5IQPA 4JDDA 3SMNA 3RDHA 4N7GA 4DHNA 2O02A 4DHMA 3IQUA 4FJ3A 4DHQA 1O9FA 4DHPA 2V7DA 4IHLA 4DHTA 4BG6A 3CU8A 5LHOA 2C63A 4DHSA 3O8IA 5HF3A 4DATA 4N7YA 2WH0A 1A4OA 2BR9A 4DX0A 3M51A 3NKXA 5EWZA 4GNTA 3P1OA 5LU1A 5D3EA 4Y5IA 3UZDA 3P1PA 2C1NA 3MHRA 3SMLA 3UX0A 3T0LA 3P1NA 4ZQ0A 3UBWA 2O8PA 2C74A 4Y3BA 4FL5A 3SMOA 5BY9A 4IEAA 1IB1A 3SMMA 4JC3A 4Y32A 2B05A 3SMKA 5EXAA 4FR3A 5D3FA 5LVZA 1QJBA 2O98A 3IQJA 5D2DA 3LW1A 1A37A 5F74A 1YWTA 3EFZA 4E2EA 4O46A 4DHRA 1O9CA 2BTPA 3P1SA 1QJAA 2C1JA 3IQVA
chains in the Genus database with same CATH superfamily
4F7RA 3AXYC 3P1RA 3U9XA 2NPMA 4ZDRA 1YZ5A 2C9KA 3P1QA 2C23A 5LU2A 3E6YA 4DNKA 3SP5A 3UALA 4D8MA 4DHOA 4DHUA 4DAUA 3M50A 4HKCA 3SPRA 4J6SA 1A38A 4N84A 5LX2A 1I5PA 4QLIA 5J31A 1O9DA 1S2XA 1O9EA 5BTVA 2BQ0A 4WRQA 3T0MA 5IQPA 4JDDA 3SMNA 3RDHA 4N7GA 4DHNA 2O02A 4DHMA 3CQGA 3X0UA 1CIYA 3IQUA 4FJ3A 4DHQA 1O9FA 4DHPA 2V7DA 4IHLA 4DHTA 4BG6A 3CU8A 5LHOA 2C63A 4DHSA 3O8IA 5HF3A 4DATA 4N7YA 2WH0A 1A4OA 3I4RA 2BR9A 4DX0A 3M51A 1URJA 3NKXA 5EWZA 4GNTA 3P1OA 5LU1A 4MOAA 5D3EA 4Y5IA 4QX3A 3UZDA 3P1PA 2C1NA 3MHRA 3SMLA 3UX0A 3T0LA 3P1NA 4ZQ0A 3UBWA 2O8PA 4QX0A 2C74A 4Y3BA 4FL5A 3SMOA 3CQCA 5BY9A 4IEAA 1IB1A 3SMMA 4JC3A 4Y32A 4QX2A 2B05A 4W8JA 3SMKA 5EXAA 4FR3A 5D3FA 5LVZA 1QJBA 2O98A 3IQJA 5D2DA 3LW1A 1A37A 5F74A 1YWTA 3EFZA 4QX1A 4ARXA 4E2EA 1JI6A 4ARYA 1DLCA 4O46A 1W99A 4DHRA 1O9CA 2BTPA 3P1SA 3EB7A 3ZHEB 1QJAA 2C1JA 3IQVA
chains in the Genus database with same CATH topology
4F7RA 3AXYC 3P1RA 3U9XA 2NPMA 4ZDRA 1YZ5A 3P1QA 2C23A 5LU2A 3E6YA 4DNKA 3SP5A 3UALA 4DHOA 4DHUA 4DAUA 3M50A 4HKCA 3SPRA 4J6SA 1A38A 4N84A 5LX2A 4QLIA 5J31A 1O9DA 1O9EA 5BTVA 2BQ0A 4WRQA 3T0MA 5IQPA 4JDDA 3SMNA 3RDHA 4N7GA 4DHNA 2O02A 4DHMA 3IQUA 4FJ3A 4DHQA 1O9FA 4DHPA 2V7DA 4IHLA 4DHTA 4BG6A 3CU8A 5LHOA 2C63A 4DHSA 3O8IA 5HF3A 4DATA 4N7YA 2WH0A 1A4OA 2BR9A 4DX0A 3M51A 3NKXA 5EWZA 4GNTA 3P1OA 5LU1A 5D3EA 4Y5IA 3UZDA 3P1PA 2C1NA 3MHRA 3SMLA 3UX0A 3T0LA 3P1NA 4ZQ0A 3UBWA 2O8PA 2C74A 4Y3BA 4FL5A 3SMOA 5BY9A 4IEAA 1IB1A 3SMMA 4JC3A 4Y32A 2B05A 3SMKA 5EXAA 4FR3A 5D3FA 5LVZA 1QJBA 2O98A 3IQJA 5D2DA 3LW1A 1A37A 5F74A 1YWTA 3EFZA 4E2EA 4O46A 4DHRA 1O9CA 2BTPA 3P1SA 1QJAA 2C1JA 3IQVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4F7R A;  3AXY C;  3P1R A;  3U9X A;  2NPM A;  4ZDR A;  1YZ5 A;  3P1Q A;  2C23 A;  5LU2 A;  3E6Y A;  4DNK A;  3SP5 A;  3UAL A;  4DHO A;  4DHU A;  4DAU A;  3M50 A;  4HKC A;  3SPR A;  4J6S A;  1A38 A;  4N84 A;  5LX2 A;  4QLI A;  5J31 A;  1O9D A;  1O9E A;  5BTV A;  2BQ0 A;  4WRQ A;  3T0M A;  5IQP A;  4JDD A;  3SMN A;  3RDH A;  4N7G A;  4DHN A;  2O02 A;  4DHM A;  3IQU A;  4FJ3 A;  4DHQ A;  1O9F A;  4DHP A;  2V7D A;  4IHL A;  4DHT A;  4BG6 A;  3CU8 A;  5LHO A;  2C63 A;  4DHS A;  3O8I A;  5HF3 A;  4DAT A;  4N7Y A;  2WH0 A;  1A4O A;  2BR9 A;  4DX0 A;  3M51 A;  3NKX A;  5EWZ A;  4GNT A;  3P1O A;  5LU1 A;  5D3E A;  4Y5I A;  3UZD A;  3P1P A;  2C1N A;  3MHR A;  3SML A;  3UX0 A;  3T0L A;  3P1N A;  4ZQ0 A;  3UBW A;  2O8P A;  2C74 A;  4Y3B A;  4FL5 A;  3SMO A;  5BY9 A;  4IEA A;  1IB1 A;  3SMM A;  4JC3 A;  4Y32 A;  2B05 A;  3SMK A;  5EXA A;  4FR3 A;  5D3F A;  5LVZ A;  1QJB A;  2O98 A;  3IQJ A;  5D2D A;  3LW1 A;  1A37 A;  5F74 A;  1YWT A;  3EFZ A;  4E2E A;  4O46 A;  4DHR A;  1O9C A;  2BTP A;  3P1S A;  1QJA A;  2C1J A;  3IQV A; 
#chains in the Genus database with same CATH topology
 4F7R A;  3AXY C;  3P1R A;  3U9X A;  2NPM A;  4ZDR A;  1YZ5 A;  2C9K A;  3P1Q A;  2C23 A;  5LU2 A;  3E6Y A;  4DNK A;  3SP5 A;  3UAL A;  4D8M A;  4DHO A;  4DHU A;  4DAU A;  3M50 A;  4HKC A;  3SPR A;  4J6S A;  1A38 A;  4N84 A;  5LX2 A;  1I5P A;  4QLI A;  5J31 A;  1O9D A;  1S2X A;  1O9E A;  5BTV A;  2BQ0 A;  4WRQ A;  3T0M A;  5IQP A;  4JDD A;  3SMN A;  3RDH A;  4N7G A;  4DHN A;  2O02 A;  4DHM A;  3CQG A;  3X0U A;  1CIY A;  3IQU A;  4FJ3 A;  4DHQ A;  1O9F A;  4DHP A;  2V7D A;  4IHL A;  4DHT A;  4BG6 A;  3CU8 A;  5LHO A;  2C63 A;  4DHS A;  3O8I A;  5HF3 A;  4DAT A;  4N7Y A;  2WH0 A;  1A4O A;  3I4R A;  2BR9 A;  4DX0 A;  3M51 A;  1URJ A;  3NKX A;  5EWZ A;  4GNT A;  3P1O A;  5LU1 A;  4MOA A;  5D3E A;  4Y5I A;  4QX3 A;  3UZD A;  3P1P A;  2C1N A;  3MHR A;  3SML A;  3UX0 A;  3T0L A;  3P1N A;  4ZQ0 A;  3UBW A;  2O8P A;  4QX0 A;  2C74 A;  4Y3B A;  4FL5 A;  3SMO A;  3CQC A;  5BY9 A;  4IEA A;  1IB1 A;  3SMM A;  4JC3 A;  4Y32 A;  4QX2 A;  2B05 A;  4W8J A;  3SMK A;  5EXA A;  4FR3 A;  5D3F A;  5LVZ A;  1QJB A;  2O98 A;  3IQJ A;  5D2D A;  3LW1 A;  1A37 A;  5F74 A;  1YWT A;  3EFZ A;  4QX1 A;  4ARX A;  4E2E A;  1JI6 A;  4ARY A;  1DLC A;  4O46 A;  1W99 A;  4DHR A;  1O9C A;  2BTP A;  3P1S A;  3EB7 A;  3ZHE B;  1QJA A;  2C1J A;  3IQV A; 
#chains in the Genus database with same CATH homology
 4F7R A;  3AXY C;  3P1R A;  3U9X A;  2NPM A;  4ZDR A;  1YZ5 A;  3P1Q A;  2C23 A;  5LU2 A;  3E6Y A;  4DNK A;  3SP5 A;  3UAL A;  4DHO A;  4DHU A;  4DAU A;  3M50 A;  4HKC A;  3SPR A;  4J6S A;  1A38 A;  4N84 A;  5LX2 A;  4QLI A;  5J31 A;  1O9D A;  1O9E A;  5BTV A;  2BQ0 A;  4WRQ A;  3T0M A;  5IQP A;  4JDD A;  3SMN A;  3RDH A;  4N7G A;  4DHN A;  2O02 A;  4DHM A;  3IQU A;  4FJ3 A;  4DHQ A;  1O9F A;  4DHP A;  2V7D A;  4IHL A;  4DHT A;  4BG6 A;  3CU8 A;  5LHO A;  2C63 A;  4DHS A;  3O8I A;  5HF3 A;  4DAT A;  4N7Y A;  2WH0 A;  1A4O A;  2BR9 A;  4DX0 A;  3M51 A;  3NKX A;  5EWZ A;  4GNT A;  3P1O A;  5LU1 A;  5D3E A;  4Y5I A;  3UZD A;  3P1P A;  2C1N A;  3MHR A;  3SML A;  3UX0 A;  3T0L A;  3P1N A;  4ZQ0 A;  3UBW A;  2O8P A;  2C74 A;  4Y3B A;  4FL5 A;  3SMO A;  5BY9 A;  4IEA A;  1IB1 A;  3SMM A;  4JC3 A;  4Y32 A;  2B05 A;  3SMK A;  5EXA A;  4FR3 A;  5D3F A;  5LVZ A;  1QJB A;  2O98 A;  3IQJ A;  5D2D A;  3LW1 A;  1A37 A;  5F74 A;  1YWT A;  3EFZ A;  4E2E A;  4O46 A;  4DHR A;  1O9C A;  2BTP A;  3P1S A;  1QJA A;  2C1J A;  3IQV A; 
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