5LU2A

Human 14-3-3 sigma complexed with long hspb6 phosphopeptide
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
230
structure length
230
Chain Sequence
ERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for the Interaction of a Human Small Heat Shock Protein with the 14-3-3 Universal Signaling Regulator.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords 14-3-3 protein sigma
total genus 96
structure length 230
sequence length 230
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-09-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 5lu2A00
2C74A 4ZQ0A 3SMKA 4DHPA 5LVZA 3MHRA 5LU2A 4DHQA 2C63A 4DAUA 3UBWA 5F74A 2NPMA 1QJAA 1QJBA 3SP5A 4FL5A 2B05A 3P1SA 4IHLA 4DHRA 3EFZA 4Y32A 1O9CA 3O8IA 4Y3BA 4E2EA 3RDHA 2O02A 5D3FA 3T0LA 3P1QA 2BR9A 4N7GA 2WH0A 4F7RA 3SMMA 1O9DA 3M51A 3M50A 4DNKA 2BTPA 5LU1A 3UX0A 4IEAA 4J6SA 5HF3A 3T0MA 1A37A 2O98A 2BQ0A 3IQVA 4FR3A 1A4OA 3UZDA 4QLIA 4O46A 3SMLA 5D2DA 2C23A 4FJ3A 4DHMA 3P1NA 5EXAA 5IQPA 4DHTA 4Y5IA 4ZDRA 3LW1A 4DHUA 4BG6A 4WRQA 4N7YA 3UALA 4DHOA 1O9EA 3CU8A 4DX0A 3NKXA 5LHOA 4DHSA 4JDDA 4DATA 3IQJA 1YZ5A 5J31A 4DHNA 5EWZA 2O8PA 3IQUA 1YWTA 3P1RA 3SMNA 5LX2A 3U9XA 5BY9A 3P1OA 5BTVA 1IB1A 3P1PA 2C1NA 3E6YA 3SPRA 5D3EA 2C1JA 1O9FA 4N84A 4HKCA 2V7DA 3SMOA 3AXYC 4JC3A 4GNTA 1A38A
chains in the Genus database with same CATH superfamily
2C74A 4ZQ0A 3SMKA 4DHPA 5LVZA 3CQCA 3MHRA 5LU2A 4DHQA 2C63A 4DAUA 3UBWA 5F74A 2NPMA 1I5PA 1QJAA 1QJBA 3SP5A 4FL5A 2B05A 3P1SA 4IHLA 4DHRA 3EFZA 1URJA 4Y32A 1O9CA 3O8IA 4D8MA 4Y3BA 4QX1A 4E2EA 3RDHA 2O02A 5D3FA 1CIYA 3T0LA 3P1QA 2BR9A 4N7GA 1DLCA 2WH0A 4F7RA 4ARYA 4QX0A 3SMMA 1O9DA 3M51A 3M50A 4DNKA 2BTPA 5LU1A 3UX0A 4IEAA 4J6SA 5HF3A 3T0MA 1A37A 2O98A 2BQ0A 3IQVA 4FR3A 1A4OA 3UZDA 4QLIA 4O46A 3SMLA 5D2DA 2C23A 4FJ3A 4DHMA 3P1NA 5EXAA 1JI6A 3EB7A 4DHTA 5IQPA 2C9KA 4Y5IA 4ZDRA 3LW1A 4DHUA 4BG6A 4WRQA 4N7YA 3UALA 4DHOA 1O9EA 3CU8A 4DX0A 3NKXA 5LHOA 4DHSA 4JDDA 4DATA 3IQJA 1YZ5A 3I4RA 4W8JA 4MOAA 3X0UA 4ARXA 4DHNA 5J31A 5EWZA 4QX2A 2O8PA 3IQUA 1YWTA 3P1RA 3SMNA 5LX2A 3U9XA 5BY9A 3P1OA 5BTVA 1IB1A 3P1PA 2C1NA 1S2XA 3E6YA 3SPRA 5D3EA 2C1JA 1O9FA 4N84A 3ZHEB 4HKCA 2V7DA 3SMOA 3AXYC 3CQGA 4JC3A 4GNTA 1W99A 1A38A 4QX3A
chains in the Genus database with same CATH topology
2C74A 4ZQ0A 3SMKA 4DHPA 5LVZA 3MHRA 5LU2A 4DHQA 2C63A 4DAUA 3UBWA 5F74A 2NPMA 1QJAA 1QJBA 3SP5A 4FL5A 2B05A 3P1SA 4IHLA 4DHRA 3EFZA 4Y32A 1O9CA 3O8IA 4Y3BA 4E2EA 3RDHA 2O02A 5D3FA 3T0LA 3P1QA 2BR9A 4N7GA 2WH0A 4F7RA 3SMMA 1O9DA 3M51A 3M50A 4DNKA 2BTPA 5LU1A 3UX0A 4IEAA 4J6SA 5HF3A 3T0MA 1A37A 2O98A 2BQ0A 3IQVA 4FR3A 1A4OA 3UZDA 4QLIA 4O46A 3SMLA 5D2DA 2C23A 4FJ3A 4DHMA 3P1NA 5EXAA 5IQPA 4DHTA 4Y5IA 4ZDRA 3LW1A 4DHUA 4BG6A 4WRQA 4N7YA 3UALA 4DHOA 1O9EA 3CU8A 4DX0A 3NKXA 5LHOA 4DHSA 4JDDA 4DATA 3IQJA 1YZ5A 5J31A 4DHNA 5EWZA 2O8PA 3IQUA 1YWTA 3P1RA 3SMNA 5LX2A 3U9XA 5BY9A 3P1OA 5BTVA 1IB1A 3P1PA 2C1NA 3E6YA 3SPRA 5D3EA 2C1JA 1O9FA 4N84A 4HKCA 2V7DA 3SMOA 3AXYC 4JC3A 4GNTA 1A38A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2C74 A;  4ZQ0 A;  3SMK A;  4DHP A;  5LVZ A;  3MHR A;  5LU2 A;  4DHQ A;  2C63 A;  4DAU A;  3UBW A;  5F74 A;  2NPM A;  1QJA A;  1QJB A;  3SP5 A;  4FL5 A;  2B05 A;  3P1S A;  4IHL A;  4DHR A;  3EFZ A;  4Y32 A;  1O9C A;  3O8I A;  4Y3B A;  4E2E A;  3RDH A;  2O02 A;  5D3F A;  3T0L A;  3P1Q A;  2BR9 A;  4N7G A;  2WH0 A;  4F7R A;  3SMM A;  1O9D A;  3M51 A;  3M50 A;  4DNK A;  2BTP A;  5LU1 A;  3UX0 A;  4IEA A;  4J6S A;  5HF3 A;  3T0M A;  1A37 A;  2O98 A;  2BQ0 A;  3IQV A;  4FR3 A;  1A4O A;  3UZD A;  4QLI A;  4O46 A;  3SML A;  5D2D A;  2C23 A;  4FJ3 A;  4DHM A;  3P1N A;  5EXA A;  5IQP A;  4DHT A;  4Y5I A;  4ZDR A;  3LW1 A;  4DHU A;  4BG6 A;  4WRQ A;  4N7Y A;  3UAL A;  4DHO A;  1O9E A;  3CU8 A;  4DX0 A;  3NKX A;  5LHO A;  4DHS A;  4JDD A;  4DAT A;  3IQJ A;  1YZ5 A;  5J31 A;  4DHN A;  5EWZ A;  2O8P A;  3IQU A;  1YWT A;  3P1R A;  3SMN A;  5LX2 A;  3U9X A;  5BY9 A;  3P1O A;  5BTV A;  1IB1 A;  3P1P A;  2C1N A;  3E6Y A;  3SPR A;  5D3E A;  2C1J A;  1O9F A;  4N84 A;  4HKC A;  2V7D A;  3SMO A;  3AXY C;  4JC3 A;  4GNT A;  1A38 A; 
#chains in the Genus database with same CATH topology
 2C74 A;  4ZQ0 A;  3SMK A;  4DHP A;  5LVZ A;  3CQC A;  3MHR A;  5LU2 A;  4DHQ A;  2C63 A;  4DAU A;  3UBW A;  5F74 A;  2NPM A;  1I5P A;  1QJA A;  1QJB A;  3SP5 A;  4FL5 A;  2B05 A;  3P1S A;  4IHL A;  4DHR A;  3EFZ A;  1URJ A;  4Y32 A;  1O9C A;  3O8I A;  4D8M A;  4Y3B A;  4QX1 A;  4E2E A;  3RDH A;  2O02 A;  5D3F A;  1CIY A;  3T0L A;  3P1Q A;  2BR9 A;  4N7G A;  1DLC A;  2WH0 A;  4F7R A;  4ARY A;  4QX0 A;  3SMM A;  1O9D A;  3M51 A;  3M50 A;  4DNK A;  2BTP A;  5LU1 A;  3UX0 A;  4IEA A;  4J6S A;  5HF3 A;  3T0M A;  1A37 A;  2O98 A;  2BQ0 A;  3IQV A;  4FR3 A;  1A4O A;  3UZD A;  4QLI A;  4O46 A;  3SML A;  5D2D A;  2C23 A;  4FJ3 A;  4DHM A;  3P1N A;  5EXA A;  1JI6 A;  3EB7 A;  4DHT A;  5IQP A;  2C9K A;  4Y5I A;  4ZDR A;  3LW1 A;  4DHU A;  4BG6 A;  4WRQ A;  4N7Y A;  3UAL A;  4DHO A;  1O9E A;  3CU8 A;  4DX0 A;  3NKX A;  5LHO A;  4DHS A;  4JDD A;  4DAT A;  3IQJ A;  1YZ5 A;  3I4R A;  4W8J A;  4MOA A;  3X0U A;  4ARX A;  4DHN A;  5J31 A;  5EWZ A;  4QX2 A;  2O8P A;  3IQU A;  1YWT A;  3P1R A;  3SMN A;  5LX2 A;  3U9X A;  5BY9 A;  3P1O A;  5BTV A;  1IB1 A;  3P1P A;  2C1N A;  1S2X A;  3E6Y A;  3SPR A;  5D3E A;  2C1J A;  1O9F A;  4N84 A;  3ZHE B;  4HKC A;  2V7D A;  3SMO A;  3AXY C;  3CQG A;  4JC3 A;  4GNT A;  1W99 A;  1A38 A;  4QX3 A; 
#chains in the Genus database with same CATH homology
 2C74 A;  4ZQ0 A;  3SMK A;  4DHP A;  5LVZ A;  3MHR A;  5LU2 A;  4DHQ A;  2C63 A;  4DAU A;  3UBW A;  5F74 A;  2NPM A;  1QJA A;  1QJB A;  3SP5 A;  4FL5 A;  2B05 A;  3P1S A;  4IHL A;  4DHR A;  3EFZ A;  4Y32 A;  1O9C A;  3O8I A;  4Y3B A;  4E2E A;  3RDH A;  2O02 A;  5D3F A;  3T0L A;  3P1Q A;  2BR9 A;  4N7G A;  2WH0 A;  4F7R A;  3SMM A;  1O9D A;  3M51 A;  3M50 A;  4DNK A;  2BTP A;  5LU1 A;  3UX0 A;  4IEA A;  4J6S A;  5HF3 A;  3T0M A;  1A37 A;  2O98 A;  2BQ0 A;  3IQV A;  4FR3 A;  1A4O A;  3UZD A;  4QLI A;  4O46 A;  3SML A;  5D2D A;  2C23 A;  4FJ3 A;  4DHM A;  3P1N A;  5EXA A;  5IQP A;  4DHT A;  4Y5I A;  4ZDR A;  3LW1 A;  4DHU A;  4BG6 A;  4WRQ A;  4N7Y A;  3UAL A;  4DHO A;  1O9E A;  3CU8 A;  4DX0 A;  3NKX A;  5LHO A;  4DHS A;  4JDD A;  4DAT A;  3IQJ A;  1YZ5 A;  5J31 A;  4DHN A;  5EWZ A;  2O8P A;  3IQU A;  1YWT A;  3P1R A;  3SMN A;  5LX2 A;  3U9X A;  5BY9 A;  3P1O A;  5BTV A;  1IB1 A;  3P1P A;  2C1N A;  3E6Y A;  3SPR A;  5D3E A;  2C1J A;  1O9F A;  4N84 A;  4HKC A;  2V7D A;  3SMO A;  3AXY C;  4JC3 A;  4GNT A;  1A38 A; 
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