|
169
|
608
|
3um8A |
Wild-type plasmodium falciparum dhfr-ts complexed with cycloguanil and nadph |
|
95
|
289
|
5hs3A |
Human thymidylate synthase complexed with dump and 3-amino-2-benzoyl-4-methylthieno[2,3-b]pyridin-6-ol |
|
90
|
281
|
5h3aA |
Structural analysis of kshv thymidylate synthase |
|
72
|
261
|
4f2vA |
Crystal structure of de novo designed serine hydrolase, northeast structural genomics consortium (nesg) target or165 |
|
95
|
287
|
4ez8A |
Crystal structure of mouse thymidylate sythase in ternary complex with n(4)-hydroxy-2'-deoxycytidine-5'-monophosphate and the cofactor product, dihydrofolate |
|
80
|
263
|
4knzA |
Thymidylate synthase ternary complex with dump and cb3717 |
|
100
|
312
|
4dq1A |
Thymidylate synthase from staphylococcus aureus. |
|
108
|
608
|
4eckA |
Crystal structure of the toxoplasma gondii ts-dhfr |
|
99
|
307
|
4eb4A |
Crystal structure of mouse thymidylate synthase in ternary complex with dump and tomudex |
|
182
|
606
|
4dp3A |
Quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with p218 and nadph |
|
93
|
285
|
4einA |
Crystal structure of mouse thymidylate synthase in binary complex with a substrate analogue and strong inhibitor, n(4)-hydroxy-2'-deoxycytidine-5'-monophosphate |
|
174
|
605
|
4dpdA |
Wild type plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts), dhf complex, nadp+, dump |
|
94
|
287
|
4e5oA |
Crystal structure of mouse thymidylate synthase in complex with dump |
|
173
|
606
|
4dphA |
Quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with p65 and nadph |
|
171
|
563
|
4eilA |
Crystal structure of the loop truncated toxoplasma gondii ts-dhfr |
|
67
|
286
|
4e28A |
Structure of human thymidylate synthase in inactive conformation with a novel non-peptidic inhibitor |
|
98
|
314
|
3v8hA |
Crystal structure of thymidylate synthase from burkholderia thailandensis |
|
104
|
315
|
3uwlB |
Crystal structure of enteroccocus faecalis thymidylate synthase (efts) in complex with 5-formyl tetrahydrofolate |
|
168
|
608
|
3um6A |
Double mutant (a16v+s108t) plasmodium falciparum dhfr-ts (t9/94) complexed with cycloguanil, nadph and dump |
|
92
|
313
|
3uwlA |
Crystal structure of enteroccocus faecalis thymidylate synthase (efts) in complex with 5-formyl tetrahydrofolate |
|
177
|
608
|
3um5A |
Double mutant (a16v+s108t) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts-t9/94) complexed with pyrimethamine, nadph, and dump |
|
78
|
264
|
3tmsA |
Plastic adaptation toward mutations in proteins: structural comparison of thymidylate synthases |
|
97
|
284
|
5wrnA |
Human thymidylate synthase complexed with dcmp |
|
98
|
284
|
5by6A |
Crystal structure of trichinella spiralis thymidylate synthase complexed with dump |
|
77
|
313
|
5j7wA |
Enterococcus faecalis thymidylate synthase complex with methotrexate |
|
89
|
283
|
5h38A |
Structural analysis of kshv thymidylate synthase |
|
94
|
285
|
5h39A |
Structural analysis of kshv thymidylate synthase |
|
96
|
287
|
5fctA |
Mouse thymidylate synthase in ternary complex with fdump and methylenetetrahydrofolate. |
|
77
|
279
|
4xseA |
Complex structure of thymidylate synthase from varicella zoster virus |
|
64
|
281
|
4xsdA |
Complex structure of thymidylate synthase from varicella zoster virus with a dump |
|
81
|
280
|
4xscA |
Complex structure of thymidylate synthase from varicella zoster virus with a phosphorylated bvdu |
|
87
|
283
|
4up1A |
Crystal structure of native human thymidylate synthase in active form |
|
103
|
316
|
4tmsA |
Plastic adaptation toward mutations in proteins: structural comparison of thymidylate synthases |
|
91
|
289
|
4psgA |
Crystal structure of c.elegans thymidylate synthase in complex with an inhibitor n(4)ohdcmp |
|
162
|
519
|
4q0dA |
Crystal structure of ts-dhfr from cryptosporidium hominis in complex with nadph, fdump, methotrexate and 2-amino-4-oxo-4,7-dihydro-pyrrolo[2,3-d]pyrimidine-methyl-phenyl-l-glutamic acid. |
|
157
|
519
|
4q0eA |
Crystal structure of ts-dhfr from cryptosporidium hominis in complex with nadph, fdump and 2-amino-4-oxo-4,7-dihydro-pyrrolo[2,3-d]pyrimidine-methyl-phenyl-l-glutamic acid. |
|
72
|
284
|
4o1uA |
Crystal structure of human thymidylate synthase mutant y202c |
|
87
|
288
|
4o1xA |
Crystal structure of human thymidylate synthase double mutant c195s-y202c |
|
84
|
313
|
4o7uA |
Etherocomplex of enteroccocus faecalis thymidylate synthase with 5-hydroxymethilene-6-hydrofolic acid and the phtalimidic inhibitor ss7 |
|
92
|
282
|
4o1xD |
Crystal structure of human thymidylate synthase double mutant c195s-y202c |
|
83
|
264
|
4lrrA |
Ternary complex between e. coli thymidylate synthase, dump, and f9 |
|
79
|
286
|
4kpwA |
Crystal structure of his-tagged human thymidylate synthase r175a mutant |
|
143
|
608
|
4ky4A |
Crystal structure of non-classical ts inhibitor 2 in complex with toxoplasma gondii ts-dhfr |
|
158
|
563
|
4kyaA |
Crystal structure of non-classical ts inhibitor 3 in complex with toxoplasma gondii ts-dhfr |
|
158
|
519
|
4ky8A |
Crystal structure of ts-dhfr from cryptosporidium hominis in complex with nadph, methotrexate, fdump and 4-((2-amino-6-methyl-4-oxo-4,7-dihydro-3h-pyrrolo[2,3-d]pyrimidin-5-yl)thio)-2-chlorophenyl)-l-glutamic acid |
|
80
|
263
|
4iskA |
Crystal structure of e.coli thymidylate synthase with dump and the bgc 945 inhibitor |
|
67
|
286
|
4jefA |
Crystal structure of human thymidylate synthase y202a in inactive conformation. |
|
86
|
289
|
4iqqA |
Crystal structure of c.elegans thymidylate synthase in complex with dump and tomudex |
|
96
|
290
|
4irrA |
Crystal structure of c.elegans thymidylate synthase in complex with dump |
|
89
|
290
|
4iswA |
Crystal structure of phosphorylated c.elegans thymidylate synthase in complex with dump |
